主持科研项目：
1. 道地药材品质保障与资源持续利用全国重点实验室开放课题（2023）
2. 国家自然科学基金面上项目 （2019）
3. 温州市重大科技创新攻关医疗卫生项目 （2019）
4. 浙江省自然科学基金面上项目 （2018）
5. 温州市科技计划项目 （2018）
6. 中国博士后科学基金第61批面上资助一等 （2017）
7. 国家自然科学基金青年项目 （2014）
8. 吉林省科技厅重点科技攻关项目 （2014）
9. 吉林省科技厅青年基金 （2012）
10. 吉林省教育厅“吉林省高校科研春苗人才”项目 （2012）
获奖情况：
1. 吉林省青年科技奖，2016
2. 中国商业联合会科学技术奖，三等奖，2020 （第一完成人）
3. 吉林市科技进步奖，三等奖，2017 （第一完成人）
4. 浙江省药学会科学技术奖，二等奖，2020（第一完成人）
5. 吉林省自然科学奖，二等奖，2019（第二完成人）
6. 吉林省自然科学奖，二等奖，2015（第二完成人）
7. 吉林省科技进步奖，二等奖，2013（第二完成人）
近五年发表论文（#同等贡献；*通讯作者）：
1. Zhang, Y.#, Cheng, Y.#, Liu, J.#, Zuo, JH., Yan, L.P., Thring, W.R., Ba, X.Q., Qi, D.K., Wu, M.J., Gao, Y.T.*, Tong, H.B.* Tauroursodeoxycholic acid functions as a critical effector mediating insulin sensitization of metformin in obese mice. Redox Biology, 2022, 57, 102481（IF：10.787，1区 Top）
2. Zuo, J.H.#, Zhang, Y.#, Wu, Y.#, Liu, J., Wu, Q.F., Shen, Y.Z., Jin, L., Wu, M.J.*, Ma, Z.L.*, Tong, H.B.* Sargassum fusiforme fucoidan ameliorates diet-induced obesity through enhancing thermogenesis of adipose tissues and modulating gut microbiota. International Journal of Biological Macromolecules, 2022, 216, 728–740（IF：8.025，1区Top）
3. Zhang, Y.#, Wu, Q.F.#, Liu, J., Zhang, Z.S., Ma, X.J., Zhang, Y.Y., Zhu, J.W., Thring, W.R., Wu, M.J., Gao, Y.T.*, Tong, H.B.* Sulforaphane alleviates high fat diet-induced insulin resistance via AMPK/Nrf2/GPx4 axis. Biomedicine & Pharmacotherapy, 2022, 152, 113273（IF：7.419，2区 Top）
4. Wu, S.Y.#, Liu, J.#, Zhang, Y.#, Song, J.X., Zhang, Z.S., Yang, Y., Wu, M.J.*, Tong, H.B.* Structural characterization and antagonistic effect against P-selectin-mediated function of SFF-32, a fucoidan fraction from Sargassum fusiforme. Journal of Ethnopharmacology, 2022, 295, 115408（IF：5.195，2区 Top）
5. He, D.#, Wu, Q.F.#, Lu, C.Y., Wu, J.L., Chen, P.C., Wu, M.J.*, Choi, J.I.*, Tong, H.B.* Pyropia yezoensis porphyran alleviates metabolic disorders via modulating gut microbiota in high sucrose-fed Drosophila melanogaster. Journal of The Science of Food and Agriculture, 2022, 102, 4802-4812（IF：4.125，2区 Top）
6. Qin, Z.Y., Yuan, X.Y., Liu, J., Shi, Z.Q., Cao, L.P., Yang, L.X., Wu, K., Lou, Y.L, Tong, H.B.*, Jiang, L.*, Du, J.M.* Albuca Bracteata polysaccharides attenuate AOM/DSS induced colon tumorigenesis via regulating oxidative stress, inflammation and gut microbiota in mice. Frontiers in Pharmacology, 2022, 13:833077（IF：5.988，2区Top）
7. Yang, Y., Mao, R., Yang, L.C. Liu, J., Wu, S.Y., Wu, M.J.*, Zhang, X., Tong, H.B.*, Ji, X.L.* Rapid and comprehensive quality assessment of Bupleuri Radix through near-infrared spectroscopy combined with chemometrics. Infrared Physics & Technology, 2022, 104051（IF：2.997，2区）
8. Wei, S.W., Zhao, Y.J., Zhou, R.M., Lin, J.W., Su, T.T., Tong, H.B.*, Wang, Z.Y. Biodegradation of polybutylene adipate-co-terephthalate by Priestia megaterium, Pseudomonas mendocina, and Pseudomonas pseudoalcaligenes following incubation in the soil. Chemosphere, 2022, 307, 135700（IF：8.943，2区Top）
9. Yang, Y., She, X.T., Cao, X.Q., Yang, L.C. Huang, J.M., Zhang, X., Su, L.J., Wu, M.J.*, Tong, H.B.*, Ji, X.L.* Comprehensive evaluation of Dendrobium officinale from different geographical origins using near-infrared spectroscopy and chemometrics. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 277:121249（IF：4.831，2区）
10. Zhang, Y.#, Liu, J.#, Mao, G.X.#, Zuo, J.H. Li, S.J., Yang, Y., Thring, R., Wu, M.J.*, Tong, H.B.* Sargassum fusiforme fucoidan alleviates diet-induced insulin resistance by inhibiting colon-derived ceramide biosynthesis. Food & Function, 2021, 12, 8440–8453.（IF：5.396，1区Top）
11. Liu, J.#, Wu, S.Y.#, Cheng, Y.#, Liu, Q., Su, L.J., Yang, Y., Zhang, X., Wu, M.J., Choi, J.-i.*, Tong, H.B.* Sargassum fusiforme alginate relieves hyperglycemia and modulates intestinal microbiota and metabolites in type 2 diabetic mice. Nutrients, 2021, 13, 2887.（IF：5.717，2区Top）
12. Gao, S.B., Gao, H.X., Dai, L.P., Han, Y.J., Lei, Z., Wang, X.Z., Chang, H.B., Liu, S.S., Wang, Z.T., Tong, H.B.*, Wu, H.* miR-126 regulates angiogenesis in myocardial ischemia by targeting HIF-1α. Experimental Cell Research, 2021, 409, 112925（IF：3.905，3区）
13. He, D., Yan L.P., Zhang, J.Q., Li, F., Wu, Y., Su, L.J., Chen, P.C., Wu, Q.F., Wu, M.J.*, Choi, J.I.*, Tong, H.B.* Sargassum fusiforme polysaccharide attenuates high-sugar-induced lipid accumulation in HepG2 cells and Drosophila melanogaster larvae. Food Science & Nutrition, 2021, 9:5590–5599.（IF：2.863，3区）
14. Wu, Q.F., Du, X.T., Feng, X.C., Cheng, H.M., Chen, Y.J., Lu, C.Y., Wu, M.J., Tong, H.B.* Chlordane exposure causes developmental delay and metabolic disorders in Drosophila melanogaster. Ecotoxicology and Environmental Safety, 2021, 225, 112739.（IF：6.291，2区Top）
15. Wu, S.Y.#, Zuo, J.H.#, Cheng, Y.#, Zhang, Y., Zhang, Z.S., Wu, M.J.*, Yang, Y.*, Tong, H.B.* Ethanol extract of Sargarsum fusiforme alleviates HFD/STZ-induced hyperglycemia in association with modulation of gut microbiota and intestinal metabolites in type 2 diabetic mice. Food Research International, 2021, 147, 110550.（IF：6.475，1区Top）
16. Wu, Q.F. #, Wu, S.Y. #, Cheng, Y. #, Zhang, Z.S., Mao, G.X., Li, S.J., Yang, Y., Zhang, X., Wu, M.J.*, Tong, H.B.* Sargassum fusiforme fucoidan modifies gut microbiota and intestinal metabolites during alleviation of hyperglycemia in type 2 diabetic mice. Food & Function, 2021, 12, 3572–3585.（IF：5.396，1区Top）
17. He, D., Yan L.P., Hu, Y.X., Wu, Q.F., Wu, M.J.*, Choi, J.I.*, Tong, H.B.* Optimization of Pyropia yezoensis porphyran by response surface methodology and its lipid-lowering effect. Marine Drugs, 2021, 19, E53.（IF：5.118，2区）
18. Zhang, Y.#, Zuo, J.H.#, Yan, L.P.#, Cheng, Y., Li, Q.J., Wu, S.Y., Chen, L., Thring, R., Yang, Y., Gao, Y.T.*, Wu, M.J.*, Tong, H.B.* Sargassum fusiforme fucoidan alleviates high-fat diet-induced obesity and insulin resistance associated with the improvement of hepatic oxidative stress and gut microbiota profile. Journal of Agricultural and Food Chemistry, 2020, 68, 10626–10638.（IF：4.192，1区Top）
19. Liu, J., Luthuli, S., Wu, Q.F., Wu, M.J.*, Choi, L.I.*, Tong, H.B.* Pharmaceutical and nutraceutical potential applications of Sargassum fulvellum. BioMed Research International, 2020, e2417410.（IF：2.276，3区）
20. Liu, J., Luthuli, S., Yang, Y., Cheng, Y., Zhang, Y., Wu, M.J.*, Choi, L.I.*, Tong, H.B.* Therapeutic and nutraceutical potentials of a brown seaweed Sargassum fusiforme. Food Science & Nutrition, 2020, 8:5195-5205.（SCI，IF：1.797，3区）
21. He, D.#, Yan L.P.#, Ma, X.J., Cheng, Y., Wu, S.Y., Zuo, J.H., Park, E.J., Liu, J., Wu, M.J., Choi, J.I.*, Tong, H.B.* Gamma-irradiation degradation of sulfated polysaccharide from a new red alga strain Pyropia yezoensis Sookwawon 104 and their in vitro antitumor bioactivity. Oncology Letters, 2020, 20(4): e91.（IF：2.311，4区）
22. Song, J.X., Wu, Y., Ma, X.J., Feng, L.J., Wang, Z.G., Jiang, G.Q.*, Tong, H.B.* Structural characterization and α-glycosidase inhibitory activity of a novel polysaccharide fraction from Aconitum coreanum. Carbohydrate Polymers, 2020, 230, 115586.（IF：7.182，1区Top）
23. Liu, J.#, Wu, S.Y.#, Chen, L., Li, Q.J., Shen, Y.Z., Jin, L., Zhang, X., Chen, P.C., Wu, M.J.*, Choi, J.I*, Tong, H.B.* Different extraction methods bring about distinct physicochemical properties and antioxidant activities of Sargassum fusiforme fucoidans. International Journal of Biological Macromolecules, 2020, 155, 1385–1392.（IF：5.162，2区Top）
24. Luthuli, S.#, Wu, S.Y.#, Cheng, Y., Zheng, X.L., Wu, M.J.*, Tong, H.B.* Therapeutic effects of fucoidan: A review on recent studies. Marine Drugs, 2019, 17, E487.（IF：3.772，2区，入选高被引论文）
25. Song, J.X., Wu, Y., Jiang, G.Q., Feng, L.J., Wang, Z.G., Yuan, G.X.*, Tong, H.B.* Sulfated polysaccharides from Rhodiola sachalinensis reduce D-gal-induced oxidative stress in NIH 3T3 cells. International Journal of Biological Macromolecules, 2019, 140, 288–293.（IF：4.784，2区）
26. He, D.#, Wu, S.Y.#, Yan, L.P., Zuo, J.H., Cheng, Y., Wang, H.F., Liu, J., Zhang, X., Choi, J.I., Wu, M.J.*, Tong, H.B.* Antitumor bioactivity of porphyran extracted from Pyropia yezoensis Chonsoo2 on human cancer cell lines. Journal of the Science of Food and Agriculture, 2019, 99: 6722–6730.（IF：2.422，2区 Top）
27. Cheng, Y.#, Sibusiso, L.#, Hou, L.F., Jiang, H.J., Chen, P.C., Zhang, X., Wu, M.J.*, Tong, H.B.* Sargassum fusiforme fucoidan modifies the gut microbiota during alleviation of streptozotocin-induced hyperglycemia in mice. International Journal of Biological Macromolecules, 2019, 131: 1162-1170. （IF：4.784，2区）
28. Wu, S.Y., Zhang, X., Liu, J., Song, J.X., Yu, P., Chen, P.C., Liao, Z.Y., Wu, M.J.*, Tong, H.B.* Physicochemical characterization of Sargassum fusiforme fucoidan fractions and their antagonistic effect against P-selectin-mediated cell adhesion. International Journal of Biological Macromolecules, 2019, 133: 656-662. （IF：4.784，2区）