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成果及论文

“Total Synthesis of Hoiamide A Using an Evans-Tishchenko Reaction As a Key Step” Org. Lett. 2019, 21, 5471-4;

 

“Total Synthesis of Psymberin (Irciniastatin A)” Org. Lett. 2019, 21, 3670-3;

 

“Discovery of Amantamide, a Selective CXCR7 Agonist from Marine Cyanobacteria” Org. Lett. 2019, 21, 1622–6;

 

“Isolation, Structure Elucidation and Biological Evaluation of Lagunamide D: A New Cytotoxic Macrocyclic Depsipeptide from Marine Cyanobacteria” Mar. Drugs 2019, 17, 83; doi:10.3390/md17020083;

 

“Chemical and Metagenomic Studies of the Lethal Black Band 2 Disease of Corals Reveal Two Broadly Distributed, Redox-Sensitive 3 Mixed Polyketide/Peptide Macrocycles” J. Nat. Prod. 2019, 82, 111-21;

 

“Solution-Phase Total Synthesis of Teixobactin” Org. Biomol. Chem. 2019, 16, 1141-53;

 

“Total Synthesis of Asperphenins A and B” Jia-Lei Yan, Yingying Cheng, Jing Chen, Ranjala Ratnayake, Long H. Dang, Hendrik Luesch, Yian Guo, Tao Ye Org. Lett. 2018, 20, 6170-3;

 

“Total Synthesis of Anti-tuberculosis Natural Products Ilamycins E1 and F” Yingying Cheng, Shoubin Tang, Yian Guo, Tao Ye Org. Lett. 2018, 20, 6166-9;

 

“Sameuramide A, a new cyclic depsipeptide isolated from an ascidian of the family Didemnidae” Bioorg. Med. Chem. 2018, 26, 3852-7;

 

“Discovery and Characterization of Brintonamides A‒E, Novel Dual Protease and GPCR Modulators from a Marine Cyanobacterium Targeting Breast Cancer Metastasis” J. Med. Chem. 2018, 61, 6364−78;

 

“Kakeromamide A, a new cyclic pentapeptide inducing astrocyte differentiation isolated from the marine cyanobacterium Moorea bouillonii” Bioorg. Med. Chem. Lett. 2018, 28, 2206-9;

 

“Studies toward the Synthesis of Iriomoteolide-2a: Construction of the C(6)−C(28) Fragment” Org. Lett. 2018, 20, 2213-5;

 

 “Formal Synthesis of Kanamienamide”, Synlett, 2018, 29, 964-8;

           

“Total Synthesis of Luteoalbusin A and Formal Synthesis of T988 C” Synlett, 2018, 29, 613-6;

 

 “Genome Mining and Assembly-Line Biosynthesis of the UCS1025A Pyrrolizidinone Family of Fungal Alkaloids” J. Am. Chem, Soc. 2018, 140, 2067-71;

 

 “Total synthesis of amphidinins E, F and epi-amphidinin F” Org. Chem. Front. 2018, 5, 629-32;

 

“Regio- and Stereospecific Construction of 3a-(1H‑Indol-3-yl)pyrrolidinoindolines and Application to the Formal Syntheses of Gliocladins B and C” Org. Lett. 2017, 19, 5134−7;

 

“Total syntheses of smenothiazoles A and B” Org. Biomol. Chem. 2017, 15, 7196-203;

 

 “Are there limits to rational chemical synthesis?” Chinese Science Bulletin 2017, 62, 2313-22;

 

“Total Synthesis and Stereochemical Assignment of Actinoranone” Chem. Eur. J. 2017, 23, 3572–6

 

“Total Synthesis and Stereochemical Assignment of Nostosin B” Marine Drugs, 2017, 15, 59; doi:10.3390/md15030058;

 

"Concise Total Synthesis of Nannocystin A" Angew. Chem. Int. Ed. 2016, 55, 13263-6.

             

“Total Synthesis and Stereochemical Assignment of Callyspongiolide” J. Am. Chem. Soc. 2016, 138, 6948-51;

 

 “Discovery, Total Synthesis and Key Structural Elements for the Immunosuppressive Activity of Cocosolide, a Symmetrical Glycosylated Macrolide Dimer from Marine Cyanobacteria” Chem. Eur. J. 2016, 22, 8158-66

 

“Towards theory driven structure elucidation of complex natural products: mandelalides and coibamide A” Org. Biomol. Chem., 2016, 14, 5826–31;

 

"Discovery of Mandelalide E and Determinants of Cytotoxicity for the Mandelalide Series", Org. Lett. 2016, 18, 1374-7;

 

“The total synthesis and stereochemical assignment of scytonemin A” Chem. Commun., 2016, 52, 1002-5;  

 

“Synthesis of Lysine Methyltransferase Inhibitors” Front. Chem., 23 July 2015, doi.org/10.3389/fchem.2015.00044;

 

"Total synthesis of the putative structure of the proposed Banyasin A", Front. Chem., 17 March 2015; DOI:10.3389/fchem.2015.00019;

 

"Studies toward the Total Synthesis of Itralamide B and Biological Evaluation of Its Structural Analogs", Marine Drugs, 2015, 13, 2085-104;

 

"Total Synthesis of Largamide B" Chem. Commun. 2015, 51, 2510-3;

 

"Total Synthesis and Stereochemical Reassignment of Mandelalide A", Angew.Chem. Int. Ed. 2014, 53, 6533-7;

 

"Grassypeptolides as Natural Inhibitors of Dipeptidyl Peptidase 8 and T-Cell Activation", ChemBioChem, 2014, 15, 799-804;

 

"Total Synthesis of the Proposed Structure for Itralamide B", Synlett, 2014, 25, 1014-8;

 

"LSD1 Regulates Pluripotency of Embryonic Stem/Carcinoma Cells through HDAC1-mediated Deacetylation of Histone H4 at Lysine 16" Mol. Cell. Biology 2014, 34, 158-79;

 

"Cross-Metathesis Approach for Stereocontrolled Synthesis of the C1–C15 Fragment of Rhizopodin", Synlett, 2014, 25, 138-42.