李玉行同学在Food Hydrocolloids期刊发表题为“Chitosan/pre-gelatinized waxy corn starch composite edible orally disintegrating film for taurine delivery”的学术论文。

本研究制备了壳聚糖/预糊化糯玉米淀粉复合可食用口腔崩解膜(ODFs)，并对其形貌、释放行为和贮存稳定性进行了研究。XRD、ATR-FTIR和显微研究结果表明，牛磺酸能均匀分散在薄膜基体中。牛磺酸的最佳添加水平为1.0% (w/w)。牛磺酸的加入改善了复合膜的表观形貌、力学性能和持水量，但只略微增加了复合膜的厚度、崩解时间和接触角。此外，牛磺酸在薄膜中表现出快速释放的行为。Ritger-Peppas模型拟合结果表明，复合膜中牛磺酸的释放机制主要为菲克扩散，骨架侵蚀较小。作为递送载体，复合膜对牛磺酸的保存有积极的影响，牛磺酸在储存过程中的保留率提高了8.34%±1.48%。该研究证实了牛磺酸ODF载体开发的可行性，为功能性膜材料的开发提供了依据。

原文链接：

https://doi.org/10.1016/j.foodhyd.2024.110710

原文摘要：

In this study, chitosan/per-gelatinized waxy corn starch composite edible orally disintegrating films (ODFs) incorporated with taurine were prepared and the morphology, release behavior and storage stability of the ODFs were investigated. The XRD, ATR-FTIR and microscopic investigation results revealed that taurine could be uniformly dispersed in the film matrix. The optimal level of taurine addition was 1.0% (w/w). The incorporation of taurine improved the apparent morphology, mechanical properties and water holding capacity while slightly increased the film thickness, disintegration time and contact angle of the composite films. In addition, taurine exhibited a rapid release behavior in the films. The fitted results of the Ritger-Peppas model indicated that the release mechanism of taurine in the composite films was mainly Fickian diffusion with minor skeleton erosion. As a delivery carrier, the composite film had a positive effect on the preservation of taurine, increasing the retention of taurine by 8.34% ± 1.48% during storage. The study confirmed the feasibility for the development of taurine ODF carriers and provided a basis for the development of functional packaging materials.