Publications:

97. Xian W, Tang Z, Zhang Q, Wang Y, Liu X*. (2024) An emerging way for bacteria to engage with host cells via protein ADP-riboxanation. Toxins, 16, 467.

96. Ge J, Wang Y, Luo ZQ, Liu X*, Qiu J*. (2024) Phosphorylation of caspases by a bacterial kinase inhibits host programmed cell death. Nat. Commun., 15, 8464.

95. Wang T, Song X, Tan J, Xian W, Zhou X, Yu M, Wang X, Xu Y, Wu T, Yuan K, Ran Y, Yang B, Fan G, Liu X*, Zhou Y*, Zhu Y*. (2024) Legionella effector LnaB is a phosphoryl-AMPylase that impairs phosphosignaling. Nature, 631, 393-401.

94. Xu J, Liang Y, Li N, Dang S, Jiang A, Liu Y, Guo Y, Yang X, Yuan Y, Zhang X, Yang Y, Du Y, Shi A, Liu X, Li D, He K*. (2024) Clathrin-associated carriers enable recycling via a kiss-and-run mechanism. Nat. Cell Biol., 26, 1652-1668.

93. Fu J, Li S, Guan H, Li C, Zhao YB, Chen TT, Xian W, Zhang Z, Liu Y, Guan Q, Wang J, Lu Q, Kang L, Zheng SR, Li J, Cao S, Das C, Liu X*, Song L*, Ouyang S*, Luo ZQ*. (2024) Legionella maintains host cell ubiquitin homeostasis by effectors with unique catalytic mechanisms. Nat. Commun., 15, 5953.

92. Bie J, Li R, Li Y, Song C, Chen Z, Zhang T, Tang Z, Su L, Zhu L, Wang J, Wan Y, Chen J*, Liu X*, Li T*, Luo J*. (2024) PKM2 aggregation drives metabolism reprogramming during aging process. Nat. Commun., 15, 5761.

91. Xian W, Fu J, Zhang Q, Li C, Zhao YB, Tang Z, Yuan Y, Wang Y, Zhou Y, Brzoic PS, Zheng N, Ouyang S, Luo ZQ*, Liu X*. (2024) The Shigella kinase effector OspG modulates host ubiquitin signaling to escape septin-cage entrapment. Nat. Commun., 15, 3890.

90. Ma K, Xian W, Liu H, Shu R, Ge J, Luo ZQ, Liu X*, Qiu J*. (2024) Bacterial ubiquitin ligases hijack the host deubiquitinase OTUB1 to inhibit mTORC1 signaling and promote autophagy. Autophagy, 20, 1968-1983.

89. Nan D, Rao C, Tang Z, Yang W, Wu P, Chen J, Xia Y, Yan J, Liu W, Zhang Z, Hu Z, Chen H, Liao Y, Mao X*, Liu X*, Zou Q*, Li Q*. (2024) Burkholderia pseudomallei BipD modulates host mitophagy to evade killing. Nat. Commun., 15, 4740.

88. Zhang Q, Xian W, Li Z, Lu Q, Chen X, Ge J, Tang Z, Liu B, Chen Z, Gao X, Hottiger MO, Zhang P*, Qiu J*, Shao F, Liu X*. (2024) Shigella induces stress granule formation by ADP-riboxanation of the eIF3 complex. Cell Rep., 43, 113789.

87. Yan Y, Xiao J, Huang F, Xian W, Yu B, Cheng R, Wu H, Lu X, Wang X, Oyejobi GK, Robinson CV, Wu H, Wu D*, Liu X*, Wang L*, Zhu B*. (2024) Phage defense system CBASS is regulated by a prokaryotic E2 enzyme imitates the ubiquitin pathway. Nat. Microbiol., 9, 1566-1578.

86. Ma K, Shu R, Liu H, Ge J, Liu J, Lu Q, Fu J, Liu X, Qiu J*. (2024) Legionella effectors SidC/SdcA ubiquitinate multiple small GTPases and SNARE proteins to promote phagosomal maturation. Cell. Mol. Life Sci., 81, 249.

85. Tan J, Xu Y, Wang X, Yan F, Xian W, Liu X, Chen Y, Zhou Y*, Zhu Y*. (2024) Molecular basis of threonine ADP-ribosylation of ubiquitin by bacterial ADP-ribosyltransferases. Nat. Chem. Biol., 20, 463-472. 

84. Yang X, Qian M, Wang Y, Qin Z, Luo M, Chen G. Yi C, Ma Y, Liu X*, Liu Z*. (2024) Thiol-based modification of MarR protein VnrR regulates resistance towards nitrofuran in Vibrio cholerae. Antioxid. Redox Signal., 40, 926-942.

83. Yuan Y, Wang X, Jin J, Tang Z, Xian W, Zhang X, Fu J*, He K*, Liu X*. (2023) The Salmonella Typhimurium effector SpvB subverts host membrane trafficking by targeting clathrin and AP-1. Mol. Cell. Proteomics, 22, 100674.

82. Ge J, Wang Y, Yu K, Luo ZQ, Liu X*, Qiu J*. (2023) Phosphoribosyl-linked serine ubiquitination of USP14 by the SidE family effectors of Legionella excludes p62 from the bacterial phagosome. Cell Rep., 42, 112817.

81. Jin J, Yuan Y, Xian W, Tang Z, Fu J, Liu X*. (2023) The ever increasing necessity of mass spectrometry in dissecting protein post-translational modifications catalyzed by bacterial effectors. Mol. Microbiol., 119, 677-686.

80. Luo M, Chen G, Yi C, Xue B, Yang X, Ma Y, Qin Z, Yan J, Liu X*, Liu Z*. (2023) Dps-dependent in vivo mutation enhances long-term host adaptation in Vibrio cholera. PLoS Pathog., 19, e1011250.

79. Shu Z, Fan M, Tu B, Tang Z, Wang H, Li H, Li H, Yuan M, Bai J, Huo S, Wang L, Zhu WG, Wang W, Liu X, Shu S, Zhao Y*. (2023) The Lin28b/Wnt5a axis drives pancreas cancer through crosstalk between the cancer associated fibroblasts and tumor epithelium. Nat. Commun., 14, 6885.

78. Yue T, Li J, Zhu J, Zuo S, Wang X, Liu Y, Liu J, Liu X, Wang P, Chen S*. (2023) Hydrogen sulfide creates a favorable immune microenvironment for colon cancer. Cancer Res., 83, 595-612.

77. Wu D, Zhang Y, Tang Z, Chen X, Ling X, Li L, Cao W, Zheng W, Wu J, Tang H, Liu X*, Luo X*, Liu T*. (2022) Creation of an organism containing a co-translationally modified nucleosome. Angew Chem. Int. Ed. Engl., 61, e202205570.

76. Wang H, Tang Z, Xue B, Lu Q, Liu X*, Zou Q*. (2022) Salmonella regulator STM0347 mediates flagellar phase variation via hin invertase. Int. J. Mol. Sci., 23, 8481.

75. Li Z, Li X, Xian W, Xie H, Sun Y, Zhang Y, Wang J, Li H, Jin C, Liu X*, Zhu Z*, Zhao M*. (2022) Construction of nano receptors for ubiquitin and ubiquitinated proteins based on the region-specific interactions between ubiquitin and polydopamine. J. Mater. Chem. B., 10, 6627-6633.

74. Torres-Sangiao E, Giddey A, Rodriguez CL, Tang Z, Liu X, Soares NC*. (2022) Proteomic approaches to unravel mechanisms of antibiotic resistance and immune evasion of bacterial pathogens. Front. Med., 9, 850347.

73. Lai X, Yu Y, Xian W, Ye F, Ju X, Luo Y, Dong H, Zhou Y, Tan W, Zhuang H, Li T, Liu X*, Ding Q*, Xiang K*. (2022) Identified human breastmilk compositions effectively inhibit SARS-CoV-2 and variants infection and replication. iScience, 25, 104136.

72. Song L, Luo J, Wang H, Huang D, Tan Y, Liu Y, Yu K, Zhang Y, Liu X, Li D*, Luo ZQ*. (2022) Legionella pneumophila regulates host cell motility by targeting Phldb2 with a 14-3-3ζ-dependent protease effector. eLife, 11, e73220. 

71. Xu Y, Cheng S, Zhou P, Ma Y, Li L, Liu X, Shao F*, Ding J*. (2022) ARF GTPases activate SopF to ADP-ribosylate the V-ATPase and inhibit endomembrane damage-induced autophagy. Nat. Struct. Mol. Biol., 29, 67-77.

70. Li Z, Liu W, Fu J, Cheng S, Xu Y, Wang Z, Liu X, Shi X, Liu Y, Qi X, Liu X*, Ding J, Shao F*. (2021) Shigella evades pyroptosis by arginine ADP-riboxanation of caspase-11. Nature, 599, 290-295.

69. Ma Y, Yang X, Wang H, Qin Z, Yi C, Shi C, Luo M, Chen G, Yan J, Liu X*, Liu Z*. (2021) CBS-derived H2S facilitates host colonization of Vibrio cholerae by promoting the iron-dependent catalase activity of KatB. PLoS Pathog., 17, e1009763.

68. Su Y, Li J, Zhang W, Ni J, Huang R, Wang Z, Cheng S, Wang Y, Tian Z, Zhou Q, Lin D, Wu W, Tang CM, Liu X*, Lu J*, Yao YF*. (2021) Methylation of PhoP by CheR regulates Salmonella virulence. mBio, 12, e02099-21.    

67. Wang C, Zhang H, Fu J, Wang M, Cai Y, Ding T, Jiang J, Koehler JE, Liu X*, Yuan C*. (2021) Bartonella type IV secretion effector BepC induces stress fiber formation through activation of GEF-H1. PLoS Pathog., 17, e1009065.

66. Niu Y, Yang L, Gao T, Dong C, Zhang B, Yin P, Hopp AK, Li D, Gan R, Wang H, Liu X, Cao X, Xie Y, Meng X, Deng H, Zhang X, Ren J, Hottiger MO, Chen Z*, Zhang Y*, Liu X*, Feng Y*. (2020) A type I-F anti-CRISPR protein inhibits the CRISPR-Cas surveillance complex by ADP-ribosylation. Mol. Cell, 80, 512-524.

65. Ai W, Yang Q, Gao Y, Liu X, Liu H, Bai Y*. (2020) In situ laser scattering electrospray ionization mass spectrometry and its application in the mechanism study of photoinduced direct C-H arylation of heteroarenes. Anal. Chem., 92, 11967-11972.

64. Zhang B, Liu B, Zhou Y, Zhang X, Zou Q, Liu X*. (2020) Contributions of mass spectrometry-based proteomics to understanding Salmonella-host interactions. Pathogens, 9, 581.

63. Cheng D, Lv H, Yao Y, Cheng S, Huang Q, Wang H, Liu X, Bae T, Li M*, Liu Q*. (2020) The roles of the site-2 protease Eep in Staphylococcus aureus. J. Bacteriol., 202, e00046-20.

62. Meng K, Zhuang X, Peng T, Hu S, Yang J, Wang Z, Fu J, Xue J, Pan X, Lv J, Liu X, Shao F, Li S*. (2020) Arginine GlcNAcylation of Rab small GTPases by the pathogen Salmonella Typhimurium. Commun. Biol., 3, 287.

61. Wu M, Feng G, Zhang B, Xu K, Wang Z, Cheng S, Chang C, Vyas A, Tang Z*, Liu X*. (2020) Phosphoproteomics reveals novel targets and phosphoprotein networks in cell cycle mediated by Dsk1 kinase. J. Proteome Res., 19, 1776-1787.

60. Huang C, Yan F, Wang X, Wan M, Tan J, Cheng S, Wang Z, Wang S, Guo X, Feng M, Liu X, Zhu Y*, Zhou Y*. (2020) Threonine ADP-ribosylation of ubiquitin by a bacterial effector family blocks host ubiquitination. Mol. Cell, 78, 641-652.

59. Ai W, Gao Y, Xue J, Liu X, Liu H, Wang J, Bai Y*. (2020) Tracing and elucidating visible-light mediated oxidation and C-H functionalization of amines using mass spectrometry. Chem. Commun., 56, 2163-2166.

58. Tian Z, Cheng S, Xia B, Jin Y, Bai F, Cheng Z, Jin S, Liu X, Wu W*. (2019) Pseudomonas aeruginosa ExsA regulates a metalloprotease ImpA that inhibits phagocytosis of macrophages. Infect. Immun., 87, e00695-19.

57. Cai R, Le S, Wu M, Cheng M, Guo Z, Ji Y, Xi H, Zhao C, Wang X, Xue Y, Wang Z, Zhang H, Fu Y, Sun C, Feng X, Lei L, Yang Y, Rahman SU, Liu X*, Han W*, Gu J*. (2019) Three capsular polysaccharide synthesis-related glucosyltransferases, GT-1, GT-2 and WcaJ, are associated with virulence and phage sensitivity of Klebsiella pneumonia. Front. Microbiol., 10, 1189.

56. Xu Y, Zhou P, Cheng S, Lu Q, Nowak K, Hopp A-K, Li L, Shi X, Zhou Z, Gao W, Li D, He H, Liu X, Ding J, Hottiger MO, Shao F*. (2019) A bacterial effector reveals the V-ATPase-ATG16L1 axis that initiates xenophagy. Cell, 178, 552-566.  

55. Gu C, Nie X, Jiang J, Chen Z, Dong Y, Zhang X, Liu J, Yu Z, Zhu Z, Liu J, Liu X, Shao Y*. (2019) Mechanistic study of oxygen reduction at liquid/liquid interfaces by hybrid ultramicroelectrodes and mass spectrometry. J. Am. Chem. Soc., 141, 13212-13221.

54. Wang Z, Sun J, Tian M, Xu Z, Liu Y, Fu J, Yan A*, Liu X*. (2019) Proteomic analysis of FNR-regulated anaerobiosis in Salmonella Typhimurium. J. Am. Soc. Mass Spectrom., 30, 1001-1012.

53. Li Z, Liu Y, Fu J, Zhang B, Cheng S, Wu M, Wang Z, Jiang J, Chang C, Liu X*. (2019) Salmonella proteomic profiling during infection distinguishes the intracellular environment of host cells. mSystems, 4, e00314-18.

52. Ren J, Sang Y, Qin R, Su Y, Cui Z, Mang Z, Li H, Lu S, Zhang J, Cheng S, Liu X, Li J, Lu J, Wu W, Zhao GP, Shao F, Yao YF*. (2019) Metabolic intermediate acetyl phosphate modulates bacterial virulence via acetylation. Emerg. Microbes Infect., 8, 55-69.

51. Wang C, Fu J, Wang M, Cai Y, Hua X, Du Y, Yang Z, Li Y, Wang Z, Sheng H, Yin N, Liu X*, Koehler JE, Yuan C*. (2019) Bartonella quintana Type IV secretion effector BepE induced selective autophagy by conjugation with K63 poly-ubiquitin chain. Cell. Microbiol., 21, e12984.

50. Wang Z, Yang X, Liu C, Li X, Zhang B, Wang B, Zhang Y, Song C, Zhang T, Liu M, Liu B, Ren M, Jiang H, Zou J, Liu X, Zhang H, Zhu WG, Yin Y, Zhang Z, Gu W, Luo J*. (2019) Acetylation of PHF5A modulates stress responses and colorectal carcinogenesis through alternative splicing-mediated up-regulation of KDM3A. Mol. Cell, 74, 1250-1263.

49. Long Y, Fu W, Li S, Ren H, Li M, Liu C, Zhang B, Xia Y, Fan Z, Xu C, Liu J, Jin Y, Bai  F, Cheng Z, Liu X, Jin S, Wu W*. (2019) Identification of novel genes that promote persister formation by repressing transcription and cell division in Pseudomonas aeruginosa. J. Antimicrob. Chemother., 74, 2575-2587.

48. Cai R, Wu M, Zhang H, Zhang Y, Cheng M, Guo Z, Ji Y, Xi H, Wang X, Xue Y, Sun C, Feng X, Lei L, Tong Y, Liu X*, Han W*, Gu J*. (2018) A smooth-type, phage-resistant Klebsiella pneumoniae mutant strain reveals OmpC is indispensable for GH-K3 infection. Appl. Environ. Microbiol., 84, e01585-18.

47. Zhang B, Ran L, Wu M, Li Z, Jiang J, Wang Z, Cheng S, Fu J, Liu X*. (2018) Shigella flexneri regulator SlyA controls bacterial acid resistance by directly activating the glutamate decarboxylation system. Front. Microbiol., 9, 2071.

46. Wang Z, McCloskey A, Cheng S, Wu M, Xue C, Fu J, Liu Y, Yu Z, Luo ZQ*, Liu X*. (2018) Regulation of the small GTPase Rab1 function by a bacterial glucosyltransferase. Cell Discov., 4, 53.

45. Wang Z, Sun J, Xia T, Liu Y, Fu J, Lo YK, Chang C, Yan A*, Liu X*. (2018) Proteomic delineation of the ArcA regulon in Salmonella Typhimurium during anaerobiosis. Mol. Cell. Proteomics, 17, 1937-1947.

44. Jiang J, Yu K, Qi L, Liu Y, Cheng S, Wu M, Wang Z, Fu J, Liu X*. (2018) A proteomic view of Salmonella Typhimurium in response to phosphate limitation. Proteomes, 6, 19.

43. Ai W, Nie H, Song S, Liu X, Bai Y*, Liu H. (2018) A versatile integrated ambient ionization source platform. J. Am. Soc. Mass Spectrom., 29, 1408-1415.

42. Fu J, Wu M, Liu X*. (2018) Proteomic approaches beyond expression profiling and PTM analysis. Anal. Bioanal. Chem., 410, 4051-4060.

41. Dong Y, Mu Y, Xie Y, Zhang Y, Han Y, Zhou Y, Wang W, Liu Z, Wu M, Wang H, Pan M, Xu N, Xu CQ, Yang M, Fan S, Deng H, Tan T, Liu X, Liu L, Li J, Wang J, Fang X, Feng Y*. (2018) Structural basis of ubiquitin modification by the Legionella effector SdeA. Nature, 557, 674-678.

40. He L, Meng H, Liu Q, Hu M, Wang Y, Chen X, Liu X, Li M*. (2018) Distinct virulent network between healthcare- and community-associated Staphylococcus aureus based on proteomic analysis. Clin. Proteomics, 15, 2.

39. Cheng S, Wang L, Liu Q, Qi L, Yu K, Wang Z, Wu M, Liu Y, Fu J, Hu M, Li M, Zhou D*, Liu X*. (2017) Identification of a novel Salmonella type III effector by quantitative secretome profiling. Mol. Cell. Proteomics, 16, 2219-2228.

38. Liu Y, Liu Q, Qi L, Ding T, Wang Z, Fu J, Hu M, Li M, Song J*, Liu X*. (2017) Temporal regulation of a Salmonella Typhimurium virulence factor by the transcriptional regulator YdcR. Mol. Cell. Proteomics, 16, 1683-1693.

37. Xu J, Xu D, Wan M, Yin L, Wang X, Wu L, Liu Y, Liu X, Zhou Y*, Zhu Y*. (2017) Structural insights into the roles of the IcmS-IcmW complex in the type IVb secretion system of Legionella pneumophila. Proc. Natl. Acad. Sci. USA, 114, 13543-13548.

36. Qi L, Hu M, Fu J, Liu Y, Wu M, Yu K, Liu X*. (2017) Quantitative proteomic analysis of host epithelial cells infected by Salmonella enterica serovar Typhimurium. Proteomics, 17, 1700092.

35. Zhou Y, Huang C, Yin L, Wan M, Wang X, Li L, Liu Y, Wang Z, Fu P, Zhang N, Chen S, Liu X, Shao F, Zhu Y*. (2017) Nε-Fatty acylation of Rho GTPases by a MARTX toxin effector. Science, 358, 528-531.

34. Sang Y, Ren J, Qin R, Liu S, Cui Z, Cheng S, Liu X, Lu J, Tao J, Yao YF*. (2017) Acetylation regulates protein stability and DNA-binding ability of HilD to modulate Salmonella Typhimurium virulence. J. Infect. Dis., 216, 1018-1026.

33. Yu K, Wang Z, Zhou F, Jiang J, Liu Y, Hu M, Liu X*. (2017) Quantitative analysis of Shigella flexneri protein expression under acid stress. Proteomics, 17, 1600381.

32. Liu Q, Hu M, Yeo WS, He L, Li T, Zhu Y, Meng H, Wang Y, Lee H, Liu X*, Li M*, Bae T*. (2017) Rewiring of the FtsH regulatory network by a single nucleotide change in saeS of Staphylococcus aureus. Sci. Rep., 7, 8456.

31. Qiu J, Yu K, Fei X, Liu Y, Nakayasu ES, Piehowski PD, Shaw JB, Puvar K, Das C, Liu X, Luo ZQ*. (2017) A unique deubiquitinase that deconjugates phosphoribosyl-linked protein ubiquitination. Cell Res., 27, 865-881.

30. Liu Q, Wang X, Qin J, Cheng S, Yeo W, He L, Ma L, Liu X, Li M*, Bae T*. (2017) The ATP-dependent protease ClpP inhibits biofilm formation by regulating Agr and cell wall hydrolase Sle1 in Staphylococcus aureus. Front. Cell. Infect. Microbiol., 7, 181.

29. Cao C, Wu M, Bing J, Tao L, Liu X*, Huang G*. (2017) Global regulatory roles of the cAMP/PKA pathway revealed by phenotypic, transcriptomic, and phosphoproteomic analyses in a null mutant of PKA catalytic subunit in Candida albicans. Mol. Microbiol., 105, 46-64.

28. Zhao Y, Hu, S, Wang H, Yu K, Guan Y, Liu X, Li N, Liu F*. (2017) DNA dendrimer–streptavidin nanocomplex: an efficient signal amplifier for construction of biosensing platforms. Anal. Chem., 89, 6907-6914.

27. Fu J, Qi L, Hu M, Liu Y, Yu K, Liu Q, Liu X*. (2017) Salmonella proteomics under oxidative stress reveals coordinated regulation of antioxidant defense with iron metabolism and bacterial virulence. J. Proteomics, 157, 52-58.

26. Liu Y, Yu K, Zhou F, Ding T, Yang Y, Hu M, Liu X*. (2017) Quantitative proteomics charts the landscape of Salmonella carbon metabolism within host epithelial cells. J. Proteome Res., 16, 788-797.

25. Qiu J, Sheedlo MJ, Yu K, Tan Y, Nakayasu ES, Das C, Liu X, Luo ZQ*. (2016) Ubiquitination independent of E1 and E2 enzymes by bacterial effectors. Nature, 533, 120-124.

24. Cai Y, Yao S, Hu M, Liu X*, Zhang J*. (2016) Manganese protoporphyrin IX reconstituted myoglobin capable of epoxidation of C=C bond with oxone. Inorg. Chem. Front., 3, 1236-1244.

23. Wang Y, Hu M, Liu Q, Qin J, Dai Y, He L, Li T, Zheng B, Zhou F, Yu K, Fang J, Liu X, Li M*, Otto M*. (2016) Role of the ESAT-6 secretion system in virulence of the emerging community-associated Staphylococcus aureus lineage ST398. Sci. Rep., 6, 25163.

22. Cao J, Yang C, Li W, Wang Q, Jiang L, Wu C, Bu Q, Wu Y, Xia G, Liu X, Luo Y*, Liu J*. (2016) Rice plasma membrane proteomics reveals Magnaporthe oryzae promotes susceptibility by sequential activation of host hormone signaling pathways. Mol. Plant Microbe Interact., 29, 902-913.

21. Yun T, Yu K, Yang S, Cui Y, Wang Z, Ren H, Chen S, Li L, Liu X*, Fang M*, Jiang X*. (2016) Acetylation of p53 at lysine 120 upregulates Apaf-1 and sensitizes mitochondrial apoptotic pathway. J. Biol. Chem., 291, 7386-7395.

20. Zhao S, Dai J, Hu M, Liu C, Meng R, Liu X, Wang C, Luo T*. (2016) Photo-induced coupling reaction of tetrazoles and carboxylic acids in the aqueous solution: applications in protein labeling. Chem. Comm., 52, 4702-4705.

19. Hu C, Yu C, Liu Y, Hou X, Liu X, Hu Y*, Jin C*. (2015) A hybrid mechanism for the Synechocystis arsenate reductase revealed by structural snapshots during arsenate reduction. J. Biol. Chem., 290, 22262-22273.

18. He W, Huang T, Tang Y, Liu Y, Wu X, Chen S, Chan W, Wang Y, Deng Z, Liu X, Chen S*, Wang L*. (2015) Regulation of DNA phosphorothioate modification in Salmonella enterica by DndB. Sci. Rep., 5, 12368.

17. Liu Y, Zhang Q, Hu M, Yu K, Fu J, Zhou F, Liu X*. (2015) Proteomic analyses of intracellular Salmonella enterica serovar Typhimurium reveal extensive bacterial adaptations to infected host epithelial cells. Infect. Immun., 83, 2897-2906.

16. Yang Y, Hu M, Yu K, Zeng X, Liu X*. (2015) Mass spectrometry-based proteomic approaches to study pathogenic bacteria-host interactions. Protein Cell, 6, 265-274.

15. Yao Q, Lu Q, Wan X, Song F, Xu Y, Hu M, Zamyatina A, Liu X, Huang N, Zhu P, Shao F*. (2014) A structural mechanism for bacterial autotransporter glycosylation by a dodecameric heptosyltransferase family. eLife, 3, e03714.

14. Lu Q, Yao Q, Xu Y, Li L, Li S, Liu Y, Gao W, Niu M, Sharon M, Ben-Nissan G, Zamyatina A, Liu X, Chen S, Shao F*. (2014) An iron-containing dodecameric heptosyltransferase family modifies bacterial autotransporters in pathogenesis. Cell Host Microbe, 16, 351-363.

13. Hu M, Liu Y, Yu K, Liu X*. (2014) Decreasing the amount of trypsin in in-gel digestion leads to diminished chemical noise and improved protein identifications. J. Proteomics, 109, 16-25.

12. Carleton H,Lara-Tejero M, Liu X, Galán JE*. (2013) Engineering the type III secretion system in non-replicating bacterial minicells for antigen delivery. Nat. Commun., 4, 1590.

11. Liu X, Gao B, Novik V, Galán JE*. (2012) Quantitative proteomics of intracellular Campylobacter jejuni reveals metabolic reprogramming. PLoS Pathog., 8, e1002562.

10. Spanò S, Liu X, Galán JE*. (2011) Proteolytic targeting of Rab29 by an effector protein distinguishes the intracellular compartment of human-adapted and broad-host Salmonella. Proc. Natl. Acad. Sci. USA, 108, 18418-18423.

9. Mukherjee S^#, Liu X^#, Arasaki K, McDonough J, Galán JE, Roy CR*. (2011) Modulation of Rab GTPase function by a protein phosphocholine transferase. Nature, 477, 103-106. (^#equal contribution)

8. Lara-Tejero M, Kato J, Wagner S, Liu X, Galán JE*. (2011) A sorting platform determines the order of protein secretion in bacterial type III systems. Science, 331, 1188-1191.

7. Liu X, Afrane M, Clemmer DE, Zhong G, Nelson DE*. (2010) Identification of Chlamydia trachomatis outer membrane proteins by differential proteomics. J. Bacteriol., 192, 2852-2860.

6. Liu X, Miller BR, Rebec GV, Clemmer DE*. (2007) Protein expression in the striatum and cortex regions of the brain for a mouse model of Huntington’s disease. J. Proteome Res., 6, 3134-3142.

5. Liu X, Valentine SJ, Plasencia MD, Trimpin S, Naylor S, Clemmer DE*. (2007) Mapping the human plasma proteome by SCX-LC-IMS-MS. J. Am. Soc. Mass Spectrom., 18, 1249-1264.

4. Valentine SJ, Plasencia MD, Liu X, Krishnan M, Naylor S, Udseth HR, Smith RD, Clemmer DE*. (2006) Toward plasma proteome profiling with ion mobility-mass spectrometry. J. Proteome Res., 5, 2977-2984.

3. Valentine SJ, Liu X, Plasencia MD, Hilderbrand AE, Kurulugama RT, Koeniger SL, Clemmer DE*. (2005) Developing liquid chromatography ion mobility mass spectrometry techniques. Expert Rev. Proteomics, 2, 553-565.

2. Liu X, Plasencia MD, Ragg S, Valentine SJ, Clemmer DE*. (2004) Development of high-throughput dispersive LC-ion mobility-TOFMS techniques for analyzing the human plasma proteome. Brief. Funct. Genomic. Proteomic., 3, 177-186.

1. Liu X, Bruening ML*. (2004) Size-selective transport of uncharged solutes through multilayer polyelectrolyte membranes. Chem. Mater., 16, 351-357.