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成果及论文

(*Co-first author;#Co-corresponding author)

  1. Fan Jibiao*Leisheng Shi*Liu Qi*Zhu ZhipengWang FanSong RunxianSu JimengZhou DeguiChen XiaoLi KailongXue Lixiang#Sun Lichao#Mao Fengbiao#;Annotation and evaluation of base editing outcomes in multiple cell types using CRISPRbase, Nucleic Acids Research (2023).
  2. Wang LuChen YifanChen RaoMao Fengbiao#Sun Zhongsheng#Liu Xiangdong#;Risk modelling of single cell transcriptomes reveals the heterogeneity of immune infiltration in hepatocellular carcinomaJournal of Biological Chemistry, 25 January 2023, 102948.
  3. Zhao Xiaolu*; Shi Leisheng*; Ruan Shasha*; Bi Wenjian; Chen Yifan; Chen Lin; Liu Yifan; Li Mingkun#; Qiao, Jie#Mao, Fengbiao#; CircleBase: an integrated resource and analysis platform for human eccDNAsNucleic Acids Research 2022, 50(D1): D72-D82.
  4. Li Shasha *; Lu Chenyang*; Zhang Yuan ; Zhao Xiaolu; Lin Kequan; Kong Xiufang; David Fox; Xue Lixiang; Sun Lichao#; Liu Yi #; Mao Fengbiao#Genetic association and single-cell transcriptome analyses reveal distinct features connecting autoimmunity with cancersiScience (2022).
  5. Shi Xiaohui*; Teng Huajing; Shi Leisheng; Bi Wenjian; Wei Wenqing; Mao Fengbiao#; Sun Zhongsheng#Comprehensive evaluation of computational methods for predicting cancer driver genesBriefings in Bioinformatics2022, 23(2), 1–14
  6. Wang Tao*; Ruan Shasha*; Zhao Xiaolu; Shi Xiaohui; Teng Huajing; Zhong Jianing; You Mingcong; Xia Kun#; Sun Zhongsheng#Mao Fengbiao#; OncoVar: an integrated database and analysis platform for oncogenic driver variants in cancersNucleic Acids Research, 2021, 49(D1): D1289-D 1301.
  7. Teng Huajing*; Wei Wenqing*; Li Qinglan; Xue Meiying; Shi Xiaohui; Li Xianfeng; Mao Fengbiao#; Sun Zhongsheng#Prevalence and architecture of posttranscriptionally impaired synonymous mutations in 8,320 genomes across 22 cancer typesNucleic Acids Research, 2020, 48(3): 1192- 1205
  8. Li Qiang*Mao Fengbiao*; Zhou Bo*; Huang Yuanhao; Zou Zhenhua; Aaron D denDekker; Xu Jing; Sean Hou; Liu Jie; Dou Yali; Rajesh C Rao#p53 Integrates Temporal WDR5 Inputs during Neuroectoderm and Mesoderm Differentiation of Mouse Embryonic Stem CellsCell Reports, 2020, 30(2): 465-480.e6.
  9. Li Guobing*; Ruan Shasha*; Zhao Xiaolu; Liu Qi; Dou Yali#Mao Fengbiao#; Transcriptomic signatures and repurposing drugs for COVID-19 patients: findings of bioinformatics analysesComputational and Structural Biotechnology Journal, 2020, 19: 1-15
  10. Wang Haoxuan*; Wang Tao*; Zhao Xiaolu; Wu Honghu; You Mingcong; Sun Zhongsheng#; Mao Fengbiao#AI-Driver: an ensemble method for identifying driver mutations in personal cancer genomesNAR Genomics and Bioinformatics, 2020, 2(4)
  11. Li Xianfeng*; Shi Leisheng*; Wang Yan*; Zhong Jianing*; Zhao Xiaolu; Teng Huajing; Shi Xiaohui; Yang Haonan; Ruan Shasha; Li MingKun; Sun Zhong Sheng#; Zhan Qimin#Mao Fengbiao#OncoBase: a platform for decoding regulatory somatic mutations in human cancersNucleic Acids Research, 2019, 47(D1): D1044-D1055
  12. Zhao Xiaolu*; Xiong Jie*Mao Fengbiao*; Sheng Yalan; Chen Xiao; Feng Lifang; Dui Wen; Yang Wentao; Kapusta Aurelie; Feschotte Cedric; Coyne Robert S; Miao Wei; Gao Shan#; Liu Yifan#RNAi-dependent Polycomb repression controls transposable elements in TetrahymenaGenes Development, 2019, 33(5-6): 348-364. 
  13. Mao Fengbiao*; Liu Qi*; Zhao Xiaolu*; Yang Haonan; Guo Sen; Xiao Luoyuan; Li Xianfeng; Teng Huajing#; Sun Zhongsheng#; Dou Yali#; EpiDenovo: a platform for linking regulatory de nov o mutations to developmental epigenetics and diseasesNucleic Acids Research, 2018, 46(D1): D92- D99. 
  14. Teng Huajing*#Mao Fengbiao*; Liang Jialong; Xue Meiying; Wei Wenqing; Li Xianfeng; Zhang Kun; Feng Dongdong; Liu Baoguo; Sun Zhongsheng#; Transcriptomic signature associated with carcinogenesis and aggressiveness of papillary thyroid carcinomaTheranostics, 2018, 8(16): 345-4358
  15. Mao Fengbiao*; Xiao Luoyuan; Li Xianfeng; Liang Jialong; Teng Huajing; Cai Wanshi#Sun ZhongSheng#RBP-Var: a database of functional variants involved in regulation mediated by RNA-binding proteinsNucleic Acids Research, 2016, 44(D1): D154-D163
  16. Cai Wanshi*Mao Fengbiao*; Teng Huajing; Cai Tao; Zhao Fangqing; Wu Jinyu#; Sun ZhongSheng#; MBRidge: an accurate and cost-effective method for profiling DNA methylome at single-base resolutionJournal of Molecular Cell Biology, 2015, 7(4): 299-313

Participated Articles:

  1. Li Y*, Fan T*, Li X*, Liu L, Mao F, Li Y, Miao Z, Zeng C, Song W, Pan J, Zhou S, Wang H, Wang Y#, Sun ZS#, Npas3 deficiency impairs cortical astrogenesis and induces autistic-like behaviors. Cell Rep. 2022 Aug 30;40(9):111289.

  2. Yang M*, Zhang ZC*, Yuan FZ*, Deng RH, Yan X, Mao F, Chen YR#, Lu H#, Yu JK#, An immunomodulatory polypeptide hydrogel for osteochondral defect repair. Bioact Mater. 2022 May 13;19:678-689.

  3. Miao Z*, Li Y*, Mao F, Zhang J, Sun ZS#, Wang Y#, Prenatal witness stress induces intergenerational anxiety-like behaviors and altered gene expression profiles in male mice. Neuropharmacology. 2022 Jan 1;202:108857.

  4. Ma K#, Baloch Z#, Mao F, Natural Products as a Source for New Leads in Depression Treatment, Evid Based Complement Alternat Med. 2022 Jan 13;2022:9791434.

  5. Li Q*, Huang Y, Xu J, Mao F, Zhou B, Sun L, Basinski BW, Aksu M, Liu J, Dou Y, Rao RC#, p53 inactivation unmasks histone methylation-independent WDR5 functions that drive self-renewal and differentiation of pluripotent stem cells. Stem Cell Reports. 2021 Nov 9;16(11):2642-2658.

  6. Yan X*, Yang B, Chen Y, Song Y, Ye J, Pan Y, Zhou B, Wang Y, Mao F, Dong Y, Liu D#, Yu J#, Anti-Friction MSCs Delivery System Improves the Therapy for Severe Osteoarthritis. Adv Mater. 2021 Dec;33(52):e2104758.

  7. Xu J*, Zhao X*, Mao F, Basrur V, Ueberheide B, Chait BT, Allis CD, Taverna SD, Gao S#, Wang W#, Liu Y#, A Polycomb repressive complex is required for RNAi-mediated heterochromatin formation and dynamic distribution of nuclear bodies. Nucleic Acids Research, 2021,8:gkaa1262.

  8. Rogawski DS*, Deng J*, Li H*, Miao H, Borkin D, Purohit T, Song J, Chase J, Li S, Ndoj J, Klossowski S, Kim E, Mao F, Zhou B, Ropa J, Krotoska MZ, Jin Z, Ernst P, Feng X, Huang G, Nishioka K, Kelly S, He M, Wen B, Sun D, Muntean A, Dou Y, Maillard I, Cierpicki T#, Grembecka J#, Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity. Nat Commun. 2021 May 14;12(1):2792.

  9. Lee YT*, Ayoub A, Park SH, Sha L, Xu J, Mao F, Zheng W, Zhang Y, Cho US, Dou Y#. Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin, Nat Commun. 2021 May 19;12(1):2953.

  10. Khoa LTP*, Tsan YC, Mao F, Kremer DM, Sajjakulnukit P, Zhang L, Zhou B, Tong X, Bhanu NV, Choudhary C, Garcia BA, Yin L, Smith GD, Saunders TL, Bielas SL, Lyssiotis CA, Dou Y#, Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid OxidationCell Stem Cell, 2020, 27(3): 441-458.e10. 

  11. Liu L*, Inoki A, Fan K, Mao F, Shi G, Jin X, Zhao M, Ney G, Jones MA, Sun S, Dou Y, Inoki K, Qi L, Li Q#, ER associated degradation preserves hematopoietic stem cell quiescence and self-renewal by restricting mTOR activityBlood, 2020,4: blood.2020007975.

  12. Zhao X*, Li Y, Duan L, Chen X, Mao F, Juma M, Liu Y, Song W, Gao S#, Functional analysis of the methyltransferase SMYD in the single-cell model organism Tetrahymena thermophile. Marine Life Science & Technology, 2020, 2:109-122.

  13. Zhang H*, Khoa LTP, Mao F, Xu H, Zhou B, Han Y, O'Leary M, Nusrat A, Wang L, Saunders TL, Dou Y#, MLL1 Inhibition and Vitamin D Signaling Cooperate to Facilitate the Expanded Pluripotency StateCell Reports, 2019, 29(9): 2659-2671.e6. 

  14. Sun Y*, Zhou B, Mao F, Xu J, Miao H, Zou Z, Khoa LTP, Cai S, Witkin M, Koche R, Ge K, Dressler G, Levine RL, Armstrong SA, Dou Y# and Hess JL#, HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis. Cancer Cell, 2018, 34 (4): 643-658. 

  15. Li X*, Shi L, Zhang K, Wei W, Liu Q, Mao F, Li J, Cai W, Chen H, Teng H#, Li J#, Sun ZS#, CirGRDB: a database for the genome-wide deciphering circadian genes and regulatorsNucleic Acids Research, 2018, 46 (D1): D64–D70. 

  16. Liang J*, Cai W*, Feng D*, Teng H, Mao F, Jiang Y, Hu S, Li X, Zhang Y, Liu B# and Sun Z#, Genetic landscape of papillary thyroid carcinoma in the Chinese populationJournal of Pathology, 2018 Feb,244(2):215-226. 

  17. Miao Z*, Mao F, Liang J, Szyf M, Wang Y#, Sun ZS#, Anxiety-related behaviors associated with microRNA-206-3p and BDNF expression in pregnant female mice following psychological social stressMolecular Neurobiology, 2018, 55:1097–1111. 

  18. Zhong J*, Li X, Cai W, Wang Y, Dong S, Yang J, Zhang J, Wu N, Li Y, Mao F, Zeng C, Wu J, Xu X, Sun ZS#, TET1 modulates H4K16 acetylation by controlling auto-acetylation of hMOF to affect gene regulation and DNA repair functionNucleic Acids Research, 2017, 45(2):672-684. 

  19. Teng H*, Zhang Y*, Shi C*, Mao F, Cai W, Lu L, Zhao F#, Sun Z#, Zhang J#, Population Genomics Reveals Speciation and Introgression between Brown Norway Rats and Their Sibling Species, Molecular Biology and Evolution, 2017, 34(9): 2214-2228. 

  20. Zhu L*, Tan X*, Liu W, Mao F, Wu C, Zhou J, Liu X, Lu S, Ma K, Yin B, Luo J, Yuan J, Qiang B, Chen R#, Peng X#, Identification and analysis of intermediate-size noncoding RNAs in the rhesus macaque fetal brainJournal of Genetics and Genomics, 2017, 44(3):171-174. 

  21. Teng H*, Zhang Y, Shi C, Mao F, Hou L, Guo H, Sun Z, Zhang J#, Whole-Genome Sequencing Reveals Genetic Variation in the Asian House RatG3-Genes Genomes Genetics, 2016, 6(7):1969-1977. 

  22. Zhang L*, Jia Z, Mao F, Shi Y, Bu RF#, Zhang B#, Whole-exome sequencing identifies a somatic missense mutation of NBN in clear cell sarcoma of the salivary gland. Oncol Rep. 2016 Jun;35(6):3349-56.

  23. Chen S*, Li M, Zhu W, Mao F, Wang J, Sun Z#, Huang X#, A novel 10-base pair insertion mutation in exon 5 of the SOD1 gene in a Chinese family with amyotrophic lateral sclerosisNeurobiol Aging. 2016 Sep;45:212.e1-212.e4.

  24. Wang K*, Li X*, Dong S, Liang J, Mao F, Zeng C, Wu H, Wu J, Cai W#, Sun ZS#, Q-RRBS: a quantitative reduced representation bisulfite sequencing method for single-cell methylome analysesEpigenetics-US, 2015, 10 (9):775-783. 

  25. Wang Y*, Wang Y*, Liu Q, Xu G, Mao F, Qin T, Teng H, Cai W, Yu P, Cai T, Zhao M#, Sun ZS#, Xie C#, Comparative RNA-seq analysis reveals potential mechanisms mediating the conversion to androgen independence in an LNCaP progression cell modelCancer Letters, 2014, 342(1):130-138. 

  26. Wang Y*, Li G, Mao F, Li X, Liu Q, Chen L, Lv L, Wang X, Wu J, Dai W, Wang G, Zhao E, Tang KF#, Sun ZS#, Ras-induced Epigenetic Inactivation of the RRAD (Ras-related Associated with Diabetes) Gene Promotes Glucose Uptake in a Human Ovarian Cancer ModelJournal of Biological Chemistry, 2014, 289(20):14225-14238. 

  27. Wang Z*, Cai W*, Cui F, Cai T, Chen Z, Mao F, Teng H, Chen L, Wang J, Sun Z#, Huang X#, Yu P#, Identification of a novel missense (C7W) mutation of SOD1 in a large familial amyotrophic lateral sclerosis pedigreeNeurobiology of Aging, 2014, 35(3):725 e711-725. 

  28. Xie Q*, Liu Q*, Mao F, Cai W, Wu H, You M, Wang Z, Chen B, Sun ZS#, Wu J#, A Bayesian framework to identify methylcytosines from high-throughput bisulfite sequencing dataPLoS Computational Biology, 2014, 10 (9): e1003853.

  29. Teng H*, Cai W*, Zeng K, Mao F, You MC, Wang T, Zhao FQ#, Sun ZS#, Genome-wide identification and divergent transcriptional expression of StAR-related lipid transfer (START) genes in teleostsGene, 2013, 519(1):18-25.