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成果及论文

1. Zhang X, Cui H, Zhang W, *Li Z, *Gao J. Engineered tumor cell-derived vaccines against cancer: the art of combating poison with poison. Bioactive Materials. 2022;22:491-517 (IF: 16.9)

2. Zhang S, Xie F, Li K, Zhang H, Yin Y, Yu Y, Lu G, Zhang S, Wei Y, Xu K, Wu Y, Jin H, Xiao L, Bao L, *Xu C, *Li Y, *Lu Y, *Gao J. Gold Nanoparticle-Directed Autophagy Intervention for Antitumor Immunotherapy via Inhibiting Tumor Associated Macrophage M2 Polarization. Acta Pharmaceutica Sinica B. 2022;12(7):3124-3138  (IF: 14.9)

3. Xu X, Liu H, Wang S, Hua Y, Huang B, Li M, *Gao J, Wang X*, Su J*. Neutrophil-Erythrocyte Hybrid Membrane-coated Hollow Copper Sulfide Nanoparticles for Targeted and Photothermal/Anti-inflammatory Therapy of Osteoarthritis. Composites Part B. 2022;237,109855 (IF:11.3)

4. Lai Y, Wei W, Du Y, *Gao J, Li Z. Biomaterials for Helicobacter pylori therapy: therapeutic potential and future perspectives. Gut Microbes. 2022;14(1):2120747. (IF:10.2)

5. Zhang S, Li Y, Qiu X, Jiao A, Luo W, Lin X, Zhang X, Zhang Z, Hong Ji, Cai P,  Zhang Y, *Wu Y, *Gao J, *Liu C, *Li Y. Incorporating Redox-sensitive Nanogels into Bioabsorbable Nanofibrous Membrane to Acquire ROS-balance Capacity for Skin Regeneration. Bioactive Materials. 2021;6(10):3461-72. (IF: 16.9)

6. Zheng K, Tong Y, Zhang S, He R, Xiao L, Iqbal Z, Zhang Y, *Gao J, *Jiang L, *Zhang L, *Li Y. Flexible Bicolorimetric Polyacrylamide/Chitosan Hydrogels for Smart Real-Time Monitoring and Promotion of Wound Healing. Advanced Functional Materials. 2021;31(34):2102599 (IF: 19.9)

7. Zheng K,# Zhou D,# Wu L, # Li J#, Zhao B, Zhang S, He R, Xiao L, Iqbal Z, Yu L, Zhang Y, He P, Han L, *Li Y, *Gao J, *Li K. Gold-nanoparticle-based Multistage Drug Delivery System for Antitumor Therapy. Drug Deliv 2022. (Accepted, IF: 6.8)

8. Li K, Zhou D, Cui H, Mo G, Liu Y, Zheng K, Zhou Z, Li J, Dai P, Sun J, Zhang Y, *Gao J. Size-transformable gelatin/nanochitosan/doxorubicin nanoparticles with sequentially triggered drug release for anticancer therapy. Colloids and Surfaces B: Biointerfaces. 2022. (Accepted, IF: 5.2) (* corresponding author)

9. Cui H, Su Y, Wei W, *Gao J, * Zhang W. How microalgae is effective in oxygen deficiency aggravated diseases? A comprehensive review of literature. Int J Nanomedicine 2022;17:3101-3122.  (IF: 7.0)

10. Chu J, Ji W, *Gao J, * Zhang W. Nanoparticle-Based Anti-Aging Treatment of Alzheimer’s Disease. Drug Deliv. 2022;29(1):2100-2116. (IF: 6.8)

11. Zheng H, Li M, Wu L, *Gao J, * Lu Z. Progress in the application of hydrogels in immunotherapy of gastrointestinal tumors. Drug Deliv. 2022. Accepted. (IF: 6.8)

12. Zhang Y, Zhang X, Li H, Liu J, *Wei W, *Gao J. Membrane-coated biomimetic nanoparticles: a state-of-the-art multifunc-tional weapon for tumor immunotherapy. Membranes 2022, 12(8), 738 (IF: 4.5)

13. Gong B, Zhuang J,  Ji W, Chen X, Li P, Cheng W, Chu J, Liang W,  He B, *Gao J, Yin Y. The long and the short of current nanomedicines for treating Alzheimer's disease. Journal of Translational Internal Medicine. 2022. doi: 10.2478/jtim-2021-0054 (IF: 3.4)

14. Su Y, Cui He, Yang C, Li L, Xu F*, Gao J*, Zhang W * Hydrogels for the Treatment of Radiation-induced Skin and Mucosa Damages: An Up-To-Date Overview. Frontiers in Materials. 2022. (IF: 3.9)

15. Gong B, Cheng W, Ji W, Chen X, Chu J, Liang W, He B, Zhuang J, Yin Y, *Gao J,  Hydrogel: a Promising New Technique for Treating Alzheimer's Disease. Journal of Translational Internal Medicine. 2022;10(1):15-17. (IF: 3.4)

16. Zhang X, Guo X, Wu Y, Gao J. Locally injectable hydrogels for tumor immunotherapy. Gels. 2021, 7, 224. (IF: 4.7)

17. Ji W, Gong B, Jin Hong, Chen Xiaohan, Li Peng, ChengWenbin, Zhao Y, He B, Zhuang J, *Gao J, Yin Y. Recent progress towards vaccines and antibody-based therapies against Alzheimer's disease. Mini Rev Med Chem. 2021;21(19):3062-3072 (IF: 3.86).

18. Gong B, Ji W, Chen X, Li P, Cheng W, Zhao Y, He B, Zhuang J, *Gao J, Yin Y. Recent advancement in Strategies for Abnormal Protein Clearance in Alzheimer’s Disease. Mini Rev Med Chem. 2021;21(19):3062-3072 (IF: 3.86)

19. Dai D,  Yin Y, Hu Y, Lu Y, Zou H, Lu G, Wang Q, Lian Jie, *Gao J, *Shen X. Tumor RNA-Loaded Nanoliposomes Increases the Anti-tumor Immune Response in Colorectal Cancer. Drug Deliv 2021;28(1):1548-1561. (IF: 6.4) (* corresponding author)

20. Li K, Pang L, Pan X, Wang X, Wang Q, Lu Y, Dai , Gao W, *Gao J. GE11 Modified PLGA/TPGS Nanoparticles Targeting Delivery of Salinomycin to Breast Cancer Cells. Technology in Cancer Research and Treatment. 2021;20:15330338211004954. (IF: 2.0)

21. Wu Y, Zhang C, Guo R, Wu D, Shi J, Li L, Chu Y, Yuan X, *Gao J. Mesenchymal Stem Cells as a Prospective Therapy for the diabetic nephropathy. Stem Cells Int. 2021 Mar 16;2021:6620811. (IF: 5.4)

22. Zhang Y, Xie F, Yin Y, Zhang Q, Jin H, Wu Yan, Pang L,  Li J, *Gao J. Immunotherapy of tumor RNA loaded lipid nanoparticles against hepatocellular carcinoma. In J Nanomedicine  2021:16:1553-1564. (IF: 6.4)

23. Gao J, Chen X, Ma Ti,  He B, Li P, Zhao Y, Ma Y, Zhuang J, Yin Y. PEG-ceramide nanomicelles induce autophagy and degrade tau proteins in N2a cells. In J Nanomedicine  2020;15:6779-6789.  (IF: 6.4)

24. Gao J, Liu J, Xie F, Lu Y, Yin C, Shen X. Co-Delivery of Docetaxel and Salinomycin to Target Both Breast Cancer Cells and Stem Cells by PLGA/TPGS Nanoparticles. In J Nanomedicine 2019;14:9199-9216. (IF: 6.4) (* corresponding author) 

25. Li J, Xue J, Zhang H, Xie F, *Zhai L, *Gao J. Effects of TPGS emulsified PLGA nanoparticles on the absorption, pharmacokinetics, and pharmacodynamics of salinomycin sodium. Anti-Cancer Drugs 2019 Jan;30(1):72-80. (IF: 2.2)

26. Chen D, Pan X, Xie F, Lu Y, Zou H, Yin C, * Zhang Y, * Gao J. Codelivery of doxorubicin and elacridar to target both liver cancer cells and stem cells by polylactide-co-glycolide/d-alpha-tocopherol polyethylene glycol 1000 succinate nanoparticles. In J Nanomedicine 2018,13:6855-6870.  (IF: 6.4) (* corresponding author)

27. Wang J, Wu Z, Pan G, Ni J, Xie F, * Jiang B, * Wei L, * Gao J, *Zhou W. Enhanced doxorubicin delivery to hepatocellular carcinoma cells via CD147 antibody-conjugated immunoliposomes. Nanomedicine 2018;14(6):1949-1961. (IF: 6.5) (* corresponding author)

28. Wang M, Xie F, Wen X, Chen H, Zhang H, Liu J, Zhang H, Zou H, Yu Y, Chen Y, Sun Z, Wang X, Zhang G, Yin C, Sun D, *Gao J, Jiang B, Zhong Y, Lu Y. Therapeutic PEG-ceramide nanomicelles synergize with salinomycin to target both liver cancer cells and cancer stem cells. Nanomedicine (Lond) 2017;12(9):1025-1042. (IF: 5.4) (* corresponding author)

29. *Gao J, Ochyl LJ, Yang E, *Moon JJ. Cationic liposomes promote antigen cross-presentation in dendritic cells by alkalizing the lysosomal pH and limiting degradation of antigens. In J Nanomedicine 2017;12:1251-1264. (IF:  6.4) (* corresponding author)

30. Chen D, Xie F, Sun D, Yin C, *Gao J, Zhong Y. Nanomedicine-mediated combination drug therapy in tumor. Open Pharmaceutical Sciences Journal 2017;4:1-10. (* corresponding author)

31. *Gao J, Li W, Guo Y, Feng SS. Nanomedicine strategies for sustained, controlled and targeted treatment of cancer stem cells. Nanomedicine (Lond) 2016 Dec;11(24):3261-3282. (IF: 5.4) (* corresponding author)

32. Yang K, Lu Y, Xie F, Zou H, Fan X, Li B, Li W, Zhang W, Mei L, Feng SS, Yin Y, Liu Y, Zhang H, *Yin C, *Zhong Y, *Gao J. Cationic liposomes induce cell necrosis through lysosomal dysfunction and late stage autophagic flux inhibition. Nanomedicine (Lond) 2016;11(23):3117-3137. (IF: 5.4) (* corresponding author)

33. Xie F, Xu W, Yin C, Zhang G, *Zhong Y, *Gao J. Nanomedicine strategies for sustained, controlled, and targeted treatment of cancer stem cells of the digestive system. World J Gastrointest Oncol 2016;8(10):735-744. (IF: 3.4) (* corresponding author)

34. Gong Z, Chen D, Xie F, Liu J, Zhang H, Zou H, Yu Y, Chen Y, Sun Z, Wang X, Zhang H, Zhang G, Yin C, *Gao J, *Zhong Y, *Lu Y. Co-delivery of salinomycin and doxorubicin using nanoliposomes for targeting both liver cancer cells and cancer stem cells. Nanomedicine (Lond) 2016;11(19):2565-2579. (IF: 5.4) (* corresponding author)

35. Xie F, Zhang S, Liu J, Gong Z, Yang K, Zhang H, Lu Y, Zou H, Yu Y, Chen Y, Sun Z, Wang X, Zhang H, Zhang G, Li W, Li B, *Gao J, Zhong Y. Codelivery of salinomycin and chloroquine by liposomes enables synergistic antitumor activity in vitro. Nanomedicine (Lond) 2016;11(14):1831-46. (IF: 5.4) (* corresponding author)

36. Mao X, Liu J, Gong Z, Zhang H, Lu Y, Zou H, Yu Y, Chen Y, Sun Z, Li W, Li B, *Gao J, Zhong Y. iRGD-conjugated DSPE-PEG2000 nanomicelles for targeted delivery of salinomycin for treatment of both liver cancer cells and cancer stem cells. Nanomedicine (Lond) 2015;10(17):2677-95. (IF: 5.4) (* corresponding author)

37. Su X, Song H, Niu F, Yang K, Kou G, Wang X, Chen H, Li W, Guo S, Li J, Li B, Feng SS, Jiang J, Yin C, *Gao J. Co-delivery of doxorubicin and PEGylated C16-ceramide by nanoliposomes for enhanced therapy against multi-drug resistance. Nanomedicine (Lond) 2015;10(13):2033-50. (IF: 5.4) (* corresponding author)

38. Song H, Su X, Yang K, Niu F, Li J, Song J, Chen H, Li B, Li W, Qian W, Cao X, Guo S, Dai J, Feng SS, Yin C, Guo Y, *Gao J. CD20 antibody-conjugated immunoliposomes for targeted chemotherapy of melanoma cancer initiating cells. J Biomed Nanotech 2015;11(11):1927-1946. (IF: 5.3) (* corresponding author)

39. Gao J, Feng SS, Guo Y. Nanomedicine for treatment of cancer stem cells. Nanomedicine (Lond) 2014; 9(2):181-184. (IF: 5.4)

40. Gao J, Xia Y, Chen H, Yu Y, Song J, Li W, Qian W, Wang H, Dai J, Guo Y. Polymer-lipid hybrid nanoparticles conjugated anti-EGFR antibody for targeted drug delivery to hepatocellular carcinoma. Nanomedicine (Lond) 2014;9(2):279-293. (IF: 5.4)

41. Gao J *, Chen H, Yu Y, Song J, Song H, Su X, Li W, Tong X, Qian W, Wang H, Dai J, Guo Y. Inhibition of hepatocellular carcinoma growth using immunoliposomes for co-delivery of adriamycin and ribonucleotide reductase M2 siRNA. Biomaterials 2013;34(38):10084-98. (IF: 10.3) (* corresponding author)

42. Gao J *, Chen H, Song H, Su X, Niu F, Li W, Li B, Dai J, Wang H, Guo Y. Antibody-targeted immunoliposomes for cancer treatment. Mini-Rev Med Chem 2013;13(14):2026-35. (IF: 3.1) (* corresponding author)

43. Gao J, Feng SS, Guo Y. Nanomedicine against multidrug resistance in cancer treatment. Nanomedicine (Lond) 2012;7:465-468. (IF: 5.4)

44. Gao J, Yu Y, Zhang Y, Song J, Chen H, Li W, Qian W, Deng L, Kou G, Chen J, Guo Y. EGFR-specific PEGylated immunoliposomes for active siRNA delivery in hepatocellular carcinoma. Biomaterials 2012;33(1):270-282. (IF: 10.3)

45. Gao J, Liu W, Xia Y, Li W, Sun J, Chen H, Li B, Zhang D, Qian W, Meng Y, Deng L, Wang H, Chen J, Guo Y. The promotion of siRNA delivery to breast cancer overexpressing epidermal growth factor receptor through anti-EGFR antibody conjugation by immunoliposomes. Biomaterials 2011;32(13):3459-3470. (IF: 10.3)

46. Gao J, Sun J, Li H, Liu W, Zhang Y, Li B, Qian W, Wang H, Chen J, Guo Y. Lyophilized HER2-specific PEGylated immunoliposomes for active siRNA gene silencing. Biomaterials 2010;31(9):2655-2664. (IF: 10.3)

47. Gao J, Feng SS, Guo Y. Antibody engineering promotes nanomedicine for cancer treatment. Nanomedicine (Lond) 2010;5:1141-1145. (IF: 5.4)

48. Gao J, Kou G, Wang H, Chen H, Li B, Lu Y, Zhang D, Wang S, Hou S, Qian W, Dai J, Zhao J, Zhong Y, Guo Y. PE38KDEL-loaded anti-HER2 nanoparticles inhibit breast tumor progression with reduced toxicity and immunogenicity. Breast Cancer Res Treat 2009;115(1):29-41. (IF: 5.6)

49. Gao J, Zhong W, He J, Li H, Zhang H, Zhou G, Li B, Lu Y, Zou H, Kou G, Zhang D, Wang H, Guo Y, Zhong Y. Tumor-targeted PE38KDEL delivery via PEGylated anti-HER2 immunoliposomes. In J Pharm 2009;374 (1-2):145-52. (IF: 5.9)

50. Gao J, Li B, Li H, Zhang X, Zhang D, Zhao L, Wang C, Fang C, Qian W, Hou S, Kou G, Wei H, Shi S, Wang H, Guo Y. Development and characterization of a fully functional small anti-HER2 antibody. BMB rep 2009;42(10):636-641. (IF: 4.8)

51. Gao J, Kou G, Chen H, Wang H, Li B, Lu Y, Zhang D, Wang S, Hou S, Qian W, Dai J, Zhao J, Zhong Y, Guo Y. Treatment of hepatocellular carcinoma in mice with PE38KDEL type I mutant-loaded poly(lactic-co-glycolic acid) nanoparticles conjugated with humanized SM5-1 F(ab’) fragments. Mol Cancer Ther 2008;7:3399-3407. (IF: 6.3)

52. Chen H, *Gao J, Lu Y, Kou G, Zhang H, Fan L, Sun Z, Guo Y, Zhong Y. Preparation and characterization of PE38KDEL-loaded anti-HER2 nanoparticles for targeted cancer therapy. J Control Release 2008;128:209-216. (*Co-first author). (IF: 9.8)

53. Gao J, Li B. Progress on targeted anticancer nanomedicines. Chin Med Biotechnol 2008;3:143-145.

54. Kou G, *Gao J, Wang H, Chen H, Li B, Zhang D, Wang S, Hou S, Qian W, Dai J, Zhong Y, Guo Y. Preparation and characterization of paclitaxel-loaded PLGA nanoparticles coated with cationic SM5-1 single-chain antibody. BMB rep 2007;40:731-739. (*Co-first author). (IF: 4.8)