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成果及论文

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Zach H. Gray#, Damayanti Chakraborty#, Reuben R. Duttweiler#, Gulnaz D. Alekbaeva, Sedona E. Murphy, Kashish Chetal, Fei Ji, Benjamin I. Ferman, Madison A. Honer, Zhentian Wang, Cynthia Myers, Renhong Sun, H. ümit Kaniskan, Monika Maria Toma, Elena A. Bondarenko, John N. Santoro, Christopher Miranda, Megan E. Dillingham, Ran Tang, Or Gozani, Jian Jin, Tomasz Skorski, Cihangir Duy, Hayan Lee, Ruslan I. Sadreyev, and Johnathan R. Whetstine, Epigenetic balance ensures mechanistic control of MLL amplification and rearrangement, Cell 186, 1–18, October 12, 2023.


Yanran Chen#, Haomiao Su#, Jianing Zhao, Zhenkun Na, Kevin Jiang, Antonella Bacchiocchi, Ken H. Loh, Ruth Halaban, Zhentian Wang, Xiongwen Cao* and Sarah A. Slavoff* , Unannotated microprotein EMBOW regulates the interactome and chromatin and mitotic functions of WDR5, Cell Reports, Online 42, 113145, September 26, 2023.


Cefan Zhou#, Xiaoting Zhu#, Nanxi Liu#, Xueying Dong, Xuewen Zhang, Huili Huang, Yu Tang, Shicheng Liu, Mengyu Hu, Ming Wang, Xiaoling Deng, Shi Li, Rui Zhang, Yuan Huang, Hao Lyu, Shuai Xiao, Sang Luo, Declan William Ali, Marek Michalak, Xing-Zhen Chen, Zhentian Wangand Jingfeng Tang* , B-lymphoid tyrosine kinase mediated FAM83A phosphorylation elevates pancreatic tumorigenesis through interacting with β-catenin, Signal Transduction and Targeted Therapy,Publised online 17 Feb, 2023,(Impact factor 38.104, Co-Corresponding Author)


Peng Xu#, Lan Zhang#, Yao Xiao#, Wei Li#, Zhiqiang Hu#, Rukui Zhang, Jin Li, Feizhen Wu, Yanping Xi, Qingping Zou, Zhentian Wang, Rui Guo, Honghui Ma, Shihua Dong, Min Xiao, Zhicong Yang, Xiaoguang Ren, Chaochun Wei*and Wenqiang Yu*, UHRF1 regulates alternative splicing by interacting with splicing factors and U snRNAs in a H3R2me involved manner, Hum Mol Genet. 2021 Nov 1;30 (22):2110-2122


Wang Z#, Hausmann S#, Lyu R, Li TM, Lofgren SM, Flores NM, Fuentes ME, Caporicci M, Yang Z, Meiners MJ, Cheek MA, Howard SA, Zhang L, Elias JE, Kim MP, Maitra A, Wang H, Bassik MC, Keogh MC, Sage J, Gozani O*, Mazur PK*. SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy, Cancer Cell. 2020 Jun 8;37(6):834-849. (Impact factor 50.3)

Biggar KKWang ZLi SS. SnapShot: Lysine Methylation beyond Histones. Molecular Cell. 2017 Dec 7;68(5):1016-1016. 


Shen H#, Xu W#, Guo R, Rong B, Gu L, Wang Z, He C, Zheng L, Hu X, Hu Z, Shao ZM, Yang P, Wu F, Shi YG, Shi Y*, Lan F*. Suppression of Enhancer Overactivation by a RACK7-Histone Demethylase Complex. Cell. 2016 Apr 7;165(2):331-342. 

 

Ma C, Karwacki-Neisius V, Tang H, Li W, Shi ZHu HXu WWang ZKong LLv RFan Z, Zhou W, Yang PWu F, Diao J, Tan L, Shi YGLan F*Shi Y*. Nono, a Bivalent Domain Factor, Regulates Erk Signaling and Mouse Embryonic Stem Cell Pluripotency. 

Cell Reports. 2016 Oct 18;17(4):997-1007.

 

Guo R#, Zheng L#, Park JW, Lv R, Chen H, Jiao F, Xu W, Mu S, Wen H, Qiu J, Wang Z, Yang P, Wu F, Hui J, Fu X, Shi X, Shi YG, Xing Y*, Lan F*, Shi Y*. BS69/ZMYND11 reads and connects histone H3.3 lysine 36 trimethylation-decorated chromatin to regulated pre-mRNA processing. Molecular Cell. 2014 Oct 23;56(2):298-310. 

 

Ma H#, Chen H#, Guo X#, Wang Z, Sowa ME, Zheng L, Hu S, Zeng P, Guo R, Diao J, Lan F, Harper JW, Shi YG, Xu Y*, Shi Y*. M phase phosphorylation of the epigenetic regulator UHRF1 regulates its physical association with the deubiquitylase USP7 and stability. 

Proc Natl Acad Sci U S A. 2012 Mar 12;109(13):4828-4833.

 

Rajakumara E#, Wang Z#,  Ma H, Hu L, Chen H, Lin Y, Guo R, Wu F, Li H, Lan F, Shi YG, Xu Y, Patel DJ*, Shi Y*. PHD finger recognition of unmodified histone H3R2 links UHRF1 to regulation of euchromatic gene expression. Molecular Cell. 2011 Jul 22;43(2):275-284. (#Co-first author).

 

Han S, Zhang HT, Wang Z, Xie Y, Tang R, Mao Y, Li Y.DNA repair gene XRCC3 polymorphisms and cancer risk: a meta-analysis of 48 case-control studies. Eur J Hum Genet. 2006 Oct;14(10):1136-1144. 

 

Han S, Zhang S, Zhang W, Li R, Li Y, Wang Z, Xie Y, Mao Y.CTLA4 polymorphisms and ophthalmopathy in Graves' disease patients: association study and meta-analysis.Hum Immunol. 2006 Aug;67(8):618-626.