Shang Li, Liangliang Ma, Xinxin Li, Yuhan Jiang, Zhongwen Luo, Fucheng Yin, Yonglei Zhang, Yifan Chen, Siyuan Wan, Han Zhou, Lingyi Kong*, Xiaobing Wang*, Discovery of Covalent MLKL PROTAC Degraders via Optimization of a Theophylline Derivative Ligand for Treating Necroptosis, Journal of Medicinal Chemistry, 2024, 67, 17, 15353–15372, DOI: 10.1021/acs.jmedchem.4c00949

共价MLKL的PROTAC降解剂