2024
1. P. Gu , S. Wang , X. Wen , J. Tian , C. Wang , L. Zong, C.-H. Tan, Asymmetric Permanganate Dihydroxylation of Enoates: Substrate Scope, Mechanistic Insights and Application in Bicalutamide Synthesis, Organic Chemistry Frontiers, 2024, 11, 836 – 842.
2. M. Y. Ng, Z. J. Song, G. Venkatesan, S. Rodriguez-Cuenca, J. A. West, S. Yang, C.-H. Tan, P. C.-L. Ho, J. L. Griffin, A. Vidal-Puig, M. Bassetto, and T. Hagen, Conjugating uncoupler compounds with hydrophobic hydrocarbon chains to achieve adipose tissue selective drug accumulation, Scientific Reports, 2024, 14, 4932 – 4932.
3. W. Chen, L. Chen, J. Chen, W. Wu, H. Wang, R. Lee, C.-H. Tan, X. Ye, Bisguanidinium-catalyzed remote enantioselective desymmetrization with 1,2-acyl shift, Chem Catalysis, 2024, 4, 100953.
4. M. Y. Ng, Z. J. Song, C.-H. Tan, M. Bassetto, T. Hagen, Structural investigations on the mitochondrial uncouplers niclosamide and FCCP, FEBS Open Bio, 2024, 14, 1057 – 1071.
5. Q. Li, Y. Dai, X. Xu, W. Wu, W. Chen, H. Wang, C.-H. Tan, and X. Ye, Enantioselective Reduction and Sulfenylation of Isoflavanone Derivatives via Bisguanidinium Hypervalent Silicate, Organic Letters, 2024, accepted.
6. Wentao Wu, Esther Cai Xia Ang, Xinru Xu, Qi Wang, Hong Wang, Choon-Hong Tan, and Xinyi Ye, Asymmetric N-oxidation Catalyzed by Bisguanidinium Dinuclear Oxodiperoxo-molybdosulfate, Nature Communications, 2024, under revision.
7. Longyi Xi, Rajakili Selvam, Xu Chen, Juan Du, Govindasamy Sekar, Junmin Zhang and Choon-Hong Tan, Bisguanidinium- catalysed enantioselective allylic amination with sulphonated phosphine-palladium complex as counterion, Organic Chemistry Frontiers, 2024, submitted
2023
1. Xin Zhang, Fucheng Wang, and Choon-Hong Tan, Asymmetric Synthesis of S(IV) and S(VI) Stereogenic Centers, JACS Au, 2023, 3, 3, 700–714
Full text: Asymmetric Synthesis of S(IV) and S(VI) Stereogenic Centers | JACS Au
2. Ziqi Yang , Chaoran Xu , Xianxian Zhou, Choon Boon Cheong , Choon Wee Kee and Choon-Hong Tan, A chiral pentanidium and pyridinyl-sulphonamide ion pair as an enantioselective organocatalyst for Steglich rearrangement, Chem. Sci., 2023, 14, 13184-13190
2022
1. X. Zhang, E. C. X. Ang, Z. Yang, C. W. Kee and C.-H. Tan, Synthesis of chiral sulfinate esters by asymmetric condensation, Nature, 2022, 604, 298-303.
Full text: Synthesis of chiral sulfinate esters by asymmetric condensation | Nature
2021
1. X. Ye and C.-H. Tan, Enantioselective transition metal catalysis directed by chiral cations, Chem. Sci., 2021, 12, 533 – 539.
2. X. Zhang and C.-H. Tan, Stereospecific and stereoconvergent nucleophilic substitution reactions at tertiary carbon centers, Chem, 2021, 7, 1–36.
3. X. Ban, Y. Fan, T.-K. Khoa, R. Lee, C. W. Kee, Z. Jiang and C.-H. Tan, Pentanidium-Catalysed Direct Assembly of Vicinal All-Carbon Quaternary Stereocenters through C(sp3)-C(sp3) Bond Formation, CCS Chem., 2021, 3, 2192-2200.
2020
1. K. F. Chin, X. Ye, Y. Li, R. Lee, A. M. Kabylda, D. Leow, X. Zhang, E. C. X. Ang and C.-H. Tan, Bisguanidinium-Catalyzed Epoxidation of Allylic and Homoallylic Amines under Phase Transfer Conditions, ACS Cat., 2020, 10, 4, 2684 – 2691.
2. J. Ren, X. Ban, X. Zhang, S. M. Tan, R. Lee and C.-H. Tan, Kinetic and Dynamic Kinetic Resolution of Racemic Tertiary Bromides by Pentanidium-Catalyzed Phase-Transfer Azidation, Angew. Chem. Int. Ed., 2020, 59, 9055-9058.
3. E. C. X. Ang, C.-H. Tan, Golden Jubilee of Singapore National Institute of Chemistry (1970-2020): Celebrating Its Partnership with Wiley-VCH. Angew. Chem. Int. Ed., 2020, 59, 19728 – 19731.
4. E. C. X. Ang, X. Ye, C.-H. Tan, Preparation of Asymmetric Phase-Transfer Catalyst, 1,4-Bis((4S,5S)-1,3-Bis(3,5-Di-Tert-Butylbenzyl)-4,5-Diphenylimidazolidin-2-Ylidene)Piperazine-1,4-Diium Chloride. Organic Syntheses, 2020, 97, 274 – 293.
Full text: Organic Syntheses Procedure (orgsyn.org)
5. W. Chen, E. C. X. Ang, S. M. Tan, Z. Chua, J. Ren, Z. Yang, B. Teng, R. Lee, H. Lu, C.-H. Tan, Enantioselective Addition-Alkylation Of Α,Β-Unsaturated Carbonyls Via Bisguanidinium Silicate Ion Pair Catalysis. J. Am. Chem. Soc., 2020, 142, 19065 – 19070.
2019
1. X. Zhang, J. Ren, S. M. Tan, D. Tan, R. Lee, C.-H. Tan, Enantioconvergent Halogenophilic Nucleophilic Substitution (SN2X) Reaction, Science, 2019, 363, 400 – 404.
Full text: An enantioconvergent halogenophilic nucleophilic substitution (SN2X) reaction | Science
2. Q. Li, X. Li, L. Ning, C.-H. Tan, Y. Mu, R. Wang, Hyperfast water transport through biomimetic nanochannels from peptide-attached (pR)-pillar[5]arene, Small., 2019, 15, 1804678.
3. Y.-C. Gordon Ge, X.-Y. Cui, H. Jiang, J.-Y. Ren, Nicholas Lee, C.-H. Tan, Guanidine–Copper Complex Catalyzed Allylic Borylation for the Enantioconvergent Synthesis of Tertiary Cyclic Allylboronates, Angew. Chem. Int. Ed., 2019, 58, 2382 – 2386.
4. Nicholas Lee, D.S. Leow, C.-H. Tan, Enantiospecific and Enantioselective Brook Rearrangements, Asian J. Org. Chem., 2019, 8, 25 – 31.
5. July Fong, K. T. Mortensen, A. Nørskov, K. Qvortrup, L. Yang, C. H. Tan, T. E. Nielsen, M. Givskov, Itaconimides as Novel Quorum Sensing Inhibitors of Pseudomonas aeruginosa, Front. Cell. Infect. Microbiol., 2019, 8, 443.
6. X.-Y. Cui, D. Leow, C.-H. Tan, Metal-Catalysed Reactions Enabled by Guanidine-Type Ligands, Org. Biomol. Chem., 2019, 17, 4689 – 4699.
7. H.-C. Chou, D. Leow and C.-H. Tan, Recent Advances in Chiral Guanidine-Catalyzed Enantioselective Reactions, Asian J. Org. Chem., 2019, 14, 3803 – 3822.
2018
1. W. Cao, D. Tan, R. Lee, C.-H. Tan, Enantioselective 1,2-Anionotropic Rearrangement of Acylsilane through Bisguanidinium Silicate Ion Pair, J. Am. Chem. Soc, 2018, 140, 1952 – 1955.
2. M.-Y. Jin, Y. R. Liao, C.-H. Tan, R. Wang, Development of high performance nanofibrous composite membranes by optimizing polydimethylsiloxane architectures for phenol transport, J. Membr. Sci, 2018, 549, 638 – 648.
3. X.-Y. Cui, Y. Ge, H. Jiang, Davin Tan, Yunpeng Lu, Richmond Lee, C.-H. Tan, (Guanidine)copper Complex-Catalysed Dynamic Kinetic Allylic Alkynylation Under Biphasic Conditions, J. Am. Chem. Soc., 2018, 140, 8448 − 8455. (Highlighted by Synfacts 2018, 5, 14(09), 0949; contributors: Mark Lautens, Andrew Whyte)
4. Y. Liang, D. Zeng, X. Huang, L. Chan, C. Mei, P. Feng, C.-H.Tan, T. Chen, Cancer-targeted Design of Bioresponsive Prodrug with Enhanced Cellular Uptake for Precise Cancer Therapy, Drug Deliv, 2018, 25, 1350 – 1361.
5. M.-Y. Jin, Y. Liao, Y. Lin, C.-H. Tan, R. Wang, Development of Highly-Efficient ZIF-8@PDMS/PVDF Nanofibrous Composite Membrane for Phenol Removal in Aqueous-Aqueous Membrane Extractive Process, J. Membr. Sci., 2018, 568, 121 – 133.
6. Repurposing the anti-cancer drug cisplatin as an effective Pseudomonas aeruginosa infection control agent, M. Yuan, S. L. Chua, Yang Liu, D. I. Drautz-Moses, J. K. H. Yam, T. T. Aung, R. W. Beuerman, M. M. S. Salido, S. C. Schuster, C.-H. Tan, M. Givskov, L. Yang, T. E. Nielsen, Beilstein J. Org. Chem., 2018, 14, 3059 – 3069.
2017
1. J. Fong, M. Yuan, T. H. Jakobsen, D. Santos, M. M. Salido, S. L. Chua, L. Yang, C.-H. Tan, T. E. Nielsen, M. Givsgov, Disulfide bond-containing ajoene analogs as novel quorum sensing inhibitors of Pseudomonas aeruginosa, J. Med. Chem., 2017, 60, 215 – 227.
2. J. W. Kee, H. Shao, C. W. Kee, Y. Lu, H. S. Soo, C.-H. Tan, Mechanistic insights for the photoredox organocatalytic fluorination of aliphatic carbons by anthraquinone using time-resolved and DFT studies, Cat. Sci. Techol., 2017, 7, 848 – 857.
3. L. Zong, C.-H. Tan, Phase transfer and ion pairing catalysis of pentanidiums and bisguanidiniums, Acc. Chem. Res., 2017, 50, 842 – 856.
4. M. Jin, Y. Liao, C. H. Loh, C.-H. Tan, W. Rong, Preparation of PDMS-PVDF composite membranes for phenol removal in extractive membrane bioreactor, Ind. Eng. Chem. Res., 2017, 56, 3436 – 3445.
5. X. Liu, L. Lin, X. Ye, C.-H. Tan, Z. Jiang, Aerobic Oxidation of Benzylic sp3 C−H Bond through Cooperative Visible Light Photoredox Catalysis of N-Hydroxyimide and Dicyanopyrazine, Asian J. Org. Chem, 2017, 6, 422 – 425.
6. B. Teng, W. C. Lim C.-H. Tan, Recent Advances in Enantioselective Brønsted Base Organocatalytic Reactions, Synlett, 2017, 28, 1272 – 1277.
7. L. Lin, X. Bai, X. Ye, X. Zhao, C.-H. Tan, Z. Jiang, Organocatalytic Enantioselective Protonation for Photoreduction of Activated Ketones and Ketimines Induced by Visible Light, Angew. Chem. Int. Ed., 2017, 56, 13842 – 13846.
2016
1. W. Feng, D. Jiang, C.-W. Kee, H. Liu, C.-H. Tan, Bicyclic Guanidine Catalyzed Asymmetric Tandem-Isomerisation Intramolecular-Diels-Alder Reaction: The First Catalytic Enantioselective Total Synthesis of (+)-alpha-Yohimbine, Chem. Asian. J., 2016, 11, 390 – 394. (Highlighted by D. F. Taber, Org. Chem. Highlights 2016, December 26. URL: http://www.organic-chemistry.org/Highlights/2016/26December.shtm)
2. G. Wei, C. Zhang, F. Bures, X. Ye, C.-H. Tan, Z. Jiang, Enantioselective Aerobic Oxidative C(sp3)−H Olefination of Amines via Cooperative Photoredox and Asymmetric Catalysis, ACS Cat., 2016, 6, 3708 − 3712.
3. X. Ye, A. M. P. Moeljadi, K. F. Chin, H. Hirao, L. Zong, C.-H. Tan, Bisguanidinium Diphosphatobisperoxotungstate Ion-pair Catalyzed Enantioselective Sulfoxidation, Angew. Chem. Int. Ed., 2016, 55, 7101 – 7105.
4. G. Wei, C. Basheer, C.-H. Tan, Z. Jiang, Visible light photocatalysis in chemoselective functionalization of C(sp3)-H bonds enabled by organic dyes, Tetrahedron Lett., 2016, 57, 3801 – 3809.
5. B. Teng, W. Chen, S. Dong, C. W. Kee, A. G. Dhika, L. Zong, C.-H. Tan, Pentanidium- and Bisguanidinium-Catalyzed Enantioselective Alkylations Using Silylamide as Brønsted Probase, J. Am. Chem. Soc., 2016, 138, 9935 − 9940.
6. S Qiu, C.-H. Tan, Z. Jiang, Highly Chemo-, Enantio-, and Diastereo-selective [4+2] Cycloaddition of 5H-thiazol-4-ones with N-Itaconimides, Beilstein J. Org. Chem., 2016, 12, 2293–2297.
7. L. Zong, C. Wang, X. Ye, C.-H. Tan, Bisguanidinium Dinuclear Oxodiperoxomolybdosulfate [(μ2-SO4)Mo2O2(μ2-O2)2(O2)2] Ion-Pair: Characterization and Application in Asymmetric Sulfoxidation, Nat. Com., 2016, 7, 13455.
8. H. Xue, C.-H. Tan, M. W. Wong, Guanidine-catalyzed Asymmetric Strecker Reaction: Modes of Activation and Origin of Stereoselectivity, Canadian. J. Chem., 2016, 94, 1099 – 1108.
2015
1. H. Xue, D. Jiang, H. Jiang, C. W. Kee, H. Hirao, T. Nishimura, M. W. Wong, C.-H. Tan, Mechanistic Insights of Chiral Bicyclic Guanidine-catalyzed Enantioselective Reactions from Microscopic and Macroscopic Perspectives, J. Org. Chem., 2015, 80, 5745 − 5752.
2. L. Zong, S. Du, K. F. Chin, C. Wang, C.-H. Tan, Enantioselective Synthesis of Quaternary Carbon Stereocenters: Addition of 3-Substituted Oxindoles to Vinyl Sulfone Catalyzed with Pentanidiums, Angew. Chem. Int. Ed., 2015, 54, 9390 – 9393.
3. S, Duan, S. Li, X. Ye, N.-N. Du, C.-H. Tan, Z. Jiang, Enantioselective Synthesis of Dialkylated α-Hydroxy Carboxylic Acids through Asymmetric Phase-Transfer Catalysis, J Org. Chem., 2015, 80, 7770 − 7778.
4. C. Wang, L. Zong, C.-H. Tan, Enantioselective Oxidation of Alkenes with Potassium Permanganate Catalyzed by Chiral Dicationic Bisguanidinium, J. Am. Chem. Soc., 2015, 137, 10677 – 10682 (Highlighted by ACS Select Virtual Issue on Organocatalysis).
5. L. Huang, J. Li, Y. Zhao, X. Ye, Y. Liu, L. Yan, C.-H. Tan, H. Liu, Z. Jiang, Chiral Bicyclic Guanidine−Catalyzed Enantioselective Sulfenylation of Oxindoles and Benzofuran-2(3H)-ones, J. Org. Chem., 2015, 80, 8933 − 8941.
2014
1. Z. Song, M. Y. Ng, Z.-W. Lee, W. Dai, T. Hagen, P. K. Moore, D. Huang, L.-W. Deng, C.-H. Tan, Hydrogen Sulfide donors in research and drug development, Med. Chem. Commun., 2014, 5, 557–570.
2. C. W. Kee, C.-H. Tan, Selective bromination of sp3 C–H bonds by organophotoredox catalysis, Asian. J. Org. Chem., 2014, 3, 536 – 544. (25 Most Accessed Articles from Asian Journal of Organic Chemistry)
3. W. Chen, Z. Jing, K. F. Chin, B. Qiao, Y. Zhao, L. Yan, C.-H.-Tan, Z. Jiang, Catalytic asymmetric conjugate addition of mercaptans to β-substituted-β-trifluoromethyl oxazolidinone enoates: Access to chiral trifluoromethylated tertiary thioethers and thiols, Adv. Synth. Cat., 2014, 356, 1292 – 1300.
4. B. Qabazard, L. Li, J. Gruber, L. F. Ng, S. D. Kumar, P. Rose, C.-H. Tan, B. W. Dymock, F. Wei, S. Swain, B. Halliwell, S. R. Sturzenbaum and P. K. Moore,, Hydrogen sulfide is an endogenous regulator of ageing in Caenorhabditis elegans, Antioxid. Redox Signal., 2014, 20, 2621 – 2630.
5. C. W. Kee, K. F. Chin, M. W. Wong, C.-H. Tan, Selective fluorination of unactivated C-H bond via organo-photocatalysis, Chem. Commun., 2014, 50, 8211 – 8214.
6. W. He, Y. Ge, C.-H. Tan, Halogen bonding induced transfer hydrogenation reactions using Hantzsch ester, Org. Let., 2014, 16, 3244 − 3247.
7. Z. Jing, J. Liu, K. F. Chin, W. Chen, C.-H. Tan, Z. Jiang, Chiral bicylic guanidine-catalyzed conjugate addition of α-fluoro-β-ketoesters to cyclic enones, Australian J. Chem., 2014, 67, 1119 – 1123.
8. Z.-W. Lee, X.-Y. Teo, Evon Y.-W. Tay, C.-H. Tan, T. Hagen, P. K. Moore, L.-W. Deng, Utilizing hydrogen sulfide as a novel anti-cancer agent by targeting cancer glycolysis and pH imbalance, 2013, British J. Pharm., 2014, 171, 4322 – 4336.
9. L. Zong, X. Ban, C.W. Kee, C.-H. Tan, Catalytic enantioselective alkylation of sulfenate anions to chiral heterocyclic sulfoxides using halogenated pentanidiums, Angew. Chem. Int. Ed., 2014, 53, 11849 – 11853. (Highlighted by Synfacts 2014, 10, 1322; contributors: Benjamin List, Mattia Riccardo Monaco; Selected by Matteo Zanda, Synform editor to be include in the Feb 2015 issue of Synform as a Synstory)
10. Q. Liu, B. Qiao, K. F. Chin, C.-H. Tan, Z. Jiang, Asymmetric Michael addition of 5 H-oxazol-4-ones to vinyl sulfones: Stereoselective synthesis of monofluorinated analogs of 2-tertiary hydroxyl-3-methyl-substituted carboxylic acid derivatives, Adv. Synth. Cat., 2014, 356, 3777 – 3783.
2013
1. Y. C. Teo, Y. Pan, C.-H. Tan, Organic dye photocatalyzed in-situ generation of acylnitroso for Ene reactions, ChemCatChem, 2013, 5, 235 – 240.
2. Z. Han, W. Yang, C.-H. Tan, Z. Jiang, Organocatalytic asymmetric Mannich reactions of 5H-oxazol-4-ones: Highly enantio- and diastereoselective synthesis of chiral α-alkyl isoserine derivatives, Adv. Synth. Cat., 2013, 355, 1505 – 1511.
3. Z. Liu, Y. Han, L. Li, H. Lu, X. Li, M. Shirhan, M. T. Peh, L. Xie, Y. Tang, S. Zhou, X. Wang, Q. Chen, W. Dai, C.-H. Tan, P. K. Moore, Y. Ji, The hydrogen sulfide donor, GYY4137, exhibits anti-atherosclerotic activity in high fat fed apolipoprotein E-/- knockout mice, British J. Pharm., 2013, 169, 1795 – 1809.
4. L. Chen, C. S. Chao, Y. Pan, S. Dong, Y. C. Teo, J. Wang, C.-H. Tan, Amphoteric methyleneamino synthon through organic dye catalyzed-decarboxylative aminoalkylation, Org. Biomol. Chem., 2013, 11, 5922 – 5925.
5. L. Yan, Z. Han, B. Zhu, C. Yang, C.-H. Tan, and Z. Jiang, Asymmetric allylic alkylation of Morita-Baylis-Hillman carbonates with α-fluoro-β-keto esters, Beilsten J. Org. Chem., 2013, 9, 1853 – 1857.
6. W. Chen, W. Yang, F. Zhao, L. Yan, C.-H. Tan, Z. Jiang, Bicyclic guanidinium-catalyzed enantioselective phase-transfer alkylation: Comprehensive access to pyrroloindolines and furoindolines, Chem. Commun., 2013, 49, 9854 – 9856.
7. C. Yang, W. Chen, W. Yang, B. Zhu, L. Yan, C.-H. Tan, and Z. Jiang, Bicyclic-guanidine-catalyzed asymmetric Michael addition of 3-substituted oxindoles to 2-cyclopentenone, Chem. Asian J., 2013, 8, 2960 – 2964.
8. C. Wang, Cindy M. T. Goh, S. Xiao, W. Ye, C.-H. Tan, Enantioselective protonation catalyzed by chiral Brønsted bases, J. Synth. Org. Chem. Japan, 2013, 71, 1145 – 1151.
2012
1. Y. Zhao, Y. Pan, S.-B. D. Sim, C.-H. Tan, Enantioselective organocatalytic fluorination organofluoro nucleophiles, Org. Biomol. Chem., 2012, 10, 479 – 485. (Invited)
2. J. Wang, J. Chen, C. W. Kee, C.-H. Tan, Bicyclic guanidine-catalyzed enantiodivergent γ-selective asymmetric allylic amination, Angew. Chem. Int. Ed., 2012, 51, 2382 – 2386.
3. W. Yang, D. Tan, R. Lee, L. Li, Y. Pan, K.-W. Huang, C.-H. Tan, Z. Jiang, Catalytic diastereoselective tandem conjugate addition-elimination reaction of Morita-Baylis-Hillman C-adducts via C–C bond cleavage, Chem. Asian J., 2012, 7, 771 – 777.
4. Y. Zhao, X. Lim, Y. Pan, L. Zong, C.-H. Tan, K.-W. Huang, Asymmetric H/D exchange reactions of fluorinated aromatic ketones, Chem. Commun., 2012, 48, 5479 – 5481.
5. L. Li, W. Chen, W. Yang, Y. Pan, H. Liu, C.-H. Tan, Z. Jiang, Bicyclic guanidine-catalyzed asymmetric Michael additions of 3-benzyl-substituted oxindoles to N-maleimides, Chem. Commun., 2012, 48, 5124 – 5126.
6. K. S. Goh, C.-H. Tan, Metal-free Pinnick-type oxidative amidation of aldehydes, RSC Adv., 2012, 2, 5536 – 5538.
7. B. Cho, C.-H. Tan, M.-W. Wah, Origin of asymmetric induction in bicyclic guanidine-catalyzed thio-Michael reaction: A bifunctional mode of Lewis acid-Brønsted acid activation, J. Org. Chem., 2012, 77, 6553 − 6562.
8. W. Yang, L. Li, Y. Pan, H. Liu, Y. Yang, L. Yan, C.-H. Tan, Z. Jiang, Direct Asymmetric allylic alkenylation of N-itaconimides with Morita-Baylis-Hillman carbonates, J. Org. Chem., 2012, 77, 6600 − 6607.
9. S. Wang, C. T. Nai, X.-F. Jiang, Y. Pan, C.-H. Tan, M. Nesladek, Q.-H. Xu, K. P. Loh, Graphene oxide-polythiophene hybrid with broadband absorption and photocatalytic properties, J. Phys. Chem. Let., 2012, 3, 2332 − 2336.
10. W. Zhang, D. Tan, R. Lee, G. Tong, W. Chen, K.-W. Huang, C.-H. Tan, Z. Jiang, Highly enantio- and diastereoselective synthesis of γ,γ-butenolide-substituted α- and β-stereogenic amides via direct vinylogous Michael addition, Angew. Chem. Int. Ed., 2012, 51, 10069 – 10073 (Highlighted by organic-chemistry.org, Tristen Lambert; http://www.organic-chemistry.org/Highlights/2013/22July.shtm)
11. Y. Yang, F. Moinodeen, W. Chin, T. Ma, Z. Jiang, C.-H. Tan, Phase transfer pentanidium-catalyzed enantioselective a-hydroxylation of oxindole with molecular oxygen, Org. Let., 2012, 14, 4762–4765. (Highlighted by organic-chemistry.org, Tristen Lambert; http://www.organic-chemistry.org/Highlights/2013/20May.shtm)
2011
1. Y. Zhao, Y. Pan, H. Liu, Y. Yang, Z. Jiang, K.-W. Huang, C.-H. Tan, a-Fluorinated aromatic ketone as nucleophile in asymmetric organocatalytic C-C and C-N bonds formation reactions: A facile route to the construction of fluorinated quaternary stereogenic carbon centers, Chem. Eur. J., 2011, 17, 3571 – 3574.
2. T. Ma, X. Fu, C. W. Kee, L. Zong, Y. Pan, K.-W. Huang, C.-H. Tan, Pentanidium catalyzed enantioselective phase transfer conjugate addition reactions, J. Am. Chem. Soc, 2011, 133, 2828 – 2831. (Highlighted by Synfacts 2011, 5, 0556-0556; contributors: Benjamin List, Saihu Liao)
3. Y. Zhang, C. W. Kee, Richmond Lee, X. Fu, Julian Y.-T. Soh, Esther M. F. Loh, K.-W. Huang and Choon-Hong Tan, C.-H. Tan, Guanidine-catalyzed enantioselective desymmetrization of meso-aziridines, 2010, Chem. Commun., 47, 3897 – 3899.
4. B. Cho, C.-H. Tan, M.-W. Wah, Sequential catalytic role of bifunctional bicyclic guanidine in asymmetric Phospha-Michael reaction, Org. Biomol. Chem., 2011, 9, 4550 – 4557.
5. Y. Pan, C.-H. Tan, Catalytic decarboxylative reactions, a biomimetic approach inspired from polyketides biosynthesis, Synthesis, 2011, 13, 2044 – 2053. (Invited)
6. Z. W. Lee, J. Zhou, C.-S. Chen, Y. Zhao, C.-H. Tan, Ling Li, P. K. Moore, L.-W. Deng, The slow-releasing hydrogen sulfide donor, GYY4137, exhibits novel anti-cancer effects in vitro and in vivo, PLoS ONE, 2011, 6, e21077.
7. X. Fu, C.-H. Tan, Mechanistic considerations of guanidines-catalyzed reactions, 2010, Chem. Commun., 2011, 47, 8210 – 8222. (Invited)
8. W. Yang, X. Wei, Y. Pan, Richmond Lee, B. Zhu, H. Liu, L. Yan, K.-W. Huang, C.-H. Tan, Z. Jiang, Highly enantio- and diastereoselective synthesis of β-Methyl-γ-Monofluoro-Methyl substituted alcohols, Chem. Eur. J., 2011, 17, 8066 – 8070 (Designated as VIP – Very Important Paper).
9. Y. Pan, C. W. Kee, Z. Jiang, T. Ma, Y. Zhao, Y. Yang, H. Xue, C.-H. Tan, Expanding the utility of Brønsted base catalysis: Biomimetic enantioselective decarboxylative reactions, Chem. Eur. J., 2011, 17, 8363 – 8370.
10. B. Nugraha, X. Hong, X. Mo, L. Tan, W. Zhang, P.-M. Chan, C. H. Kang, Y. Wang, L. T. Beng, W. Sung, D. Choudhury, J. M. Rubens, M. McMillian, J. Silva, S. Dallas, C.-H. Tan, Z. Yue, Hanry Yu, Galactosylated cellulosic sponge for multi-well drug safety testing, Biomaterials, 2011, 32, 6982 – 6994.
11. B. Zhu, L. Yan, Y. Pan, R. Lee, H. Liu, Z. Han, K.-W. Huang, C.-H. Tan, Z. Jiang, Enantioselective Lewis Base-catalyzed highly enantioselective allylic hydroxylation of Morita-Baylis-Hillman carbonates with water, J. Org. Chem., 2011, 76, 6894 – 6900.
12. Y. L. Quek, C.-H. Tan, J. Bian, D. Huang, Air oxidation of HS- catalyzed by an mixed-valence diruthenium complex, an near-IR probe for HS- detection, Inorg. Chem., 2011, 50, 7379 – 7381.
13. Y. Pan, C. W. Kee, L. Chen and C.-H. Tan, Dehydrogenative coupling reactions catalysed by Rose Bengal using visible light irradiation, Green Chem., 2011, 13, 2682 – 2685.
14. F. Zhao, W. Zhang, Y. Yang, Y. Pan, W. Chen, H. Liu, L. Yan, C.-H. Tan, Z. Jiang, Synthesis of sulfur-substituted α-stereogenic amides and ketones: Highly enantioselective Sulfa-Michael Addition (SMA) of 1,4-dicarbonyl but-2-enes, Adv. Synth. Cat., 2011, 353, 2624 – 2630.
15. Y. Pan, S. Wang, C. W. Kee, E. Dubuisson, K. P. Loh, and C.-H. Tan, Graphene Oxide and Rose Bengal: Oxidative C-H functionalization of tertiary amines using visible light, Green Chem., 2011, 13, 3341 – 3344.
2010
1. R. Lee, Y. Yang, G. K. Tan, C.-H. Tan, K.-W. Huang. A novel heteroleptic paddlewheel diruthenium bicyclic guanidinate complex: Synthesis, structure, and scope, Dalton Transactions, 2010, 39, 723 – 725.
2. S. Huang, J. H. Chua, W. S. Yew, J. Sivaraman, P. K. Moore, C.-H. Tan, L.-W. Deng. Site-directed mutagenesis on human Cystathionine-gamma-lyase reveals insights into the modulation of H2S production, J. Mol. Bio., 2010, 396, 708 – 718.
3. Y. Pan, Y. Zhao, T. Ma, Y. Yang, H. Liu, Z. Jiang, C.-H. Tan, Enantioselective synthesis of a-fluorinated b-amino acid derivatives via asymmetric Mannich reaction and selective decarboxylation/deacylation reactions, Chem. Eur. J., 2010, 16, 779 – 782.
4. M. Whiteman, L. Li, P. C. Rose, C.-H. Tan, D. Parkinson, Philip K. Moore, The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages, Antiox. Red. Signaling, 2010, 12, 1147 – 1154.
5. H. Liu, W. Feng, Y. Zhao, D. Leow, Y. Pan, C.-H. Tan, Organic dye photocatalyzed α-oxyamination through irradiation with visible light, Green Chem., 2010, 12, 953 – 956.
6. D. Leow, C.-H. Tan, Catalytic reactions of chiral guanidines and guanidinium Salts, Synlett, 2010, 1589 – 1605. (Invited)
7. X. Mo, Q. Li, L. Wai Y. L., B. Zheng C. H. Kang, B. Nugraha, Z. Yue, R. R. Jia, H. X. Fu, D. Choudhury, T. Arooz, J. Yan, C. T. Lim, S. Shen, C.-H. Tan, Hanry Yu, Rapid construction of mechanically-confined multi-cellular structures using dendrimeric intercellular linker, Biomaterials, 2010, 31, 7455 – 7467.
8. J. Wang, H. Liu, Y. Fan, Y. Yang, Z. Jiang, C.-H. Tan Bicyclic guanidine-catalyzed direct asymmetric allylic addition of N-aryl alkylidene-succinimides, Chem. Eur. J., 2010, 16, 12534 – 12537.
9. H. Liu, W. Feng, D. Leow, W.-T. Loh, C.-H. Tan, Brønsted-base catalyzed tandem isomerization-Michael reactions of alkynes: The synthesis of oxacycles and azacycles, 2010, Adv. Synth. Cat., 352, 3373 – 3379.
2009
1. D. Leow and C.-H. Tan, Chiral guanidines catalyzed enantioselective reactions, Chem. Asian J., 2009, 4, 488 – 507. (Invited, Most accessed articles 6/2008–5/2009, Top 20 most cited article in Chem. Asian. J.)
2. Z. Jiang, Y. Yang, Y. Pan, Y. Zhao, H. Liu and C.-H. Tan, Synthesis of α-stereogenic amides and ketones by enantioselective conjugate addition of 1,4-dicarbonyl but-2-enes, Chem. Eur. J., 2009, 15, 4925 – 4930.
3. R. Lee, X. Lim, T. Chen, G. K. Tan, C.-H. Tan and K.-W. Huang. Selective formation of bicyclic guanidinium chloride complexes: Implication of the bifunctionality of guanidines. Tetrahedron Let., 2009, 50, 1560 – 1562.
4. Julian Y.-T. Soh, C.-H. Tan, Amino-indanol catalyzed enantioselective reactions of 3-hydroxy-2-pyridones, J. Am. Chem. Soc., 2009, 131, 6904 – 6905. (Highlighted by Synfacts 2009, 7, 0792-0792; contributors: Benjamin List, Saihu Liao)
5. H. Liu, D. Leow, C.-H. Tan, Enantioselective synthesis of chiral allenoates by guanidine-catalyzed isomerization of alkynoates, J. Am. Chem. Soc, 2009, 131, 7212 – 7213. (Highlighted by Synfacts 2009, 7, 0794-0794; contributors: Benjamin List, Steffen Müller)
6. Z. Jiang, Y. Pan, Y. Zhao, T. Ma, R. Lee, Y. Yang, K.-W. Huang, M. W. Wong and C.-H. Tan, Synthesis of chiral quaternary C-F bond through highly enantioselective and diastereoselective guanidine-catalyzed addition of fluorocarbon nucleophiles, Angew. Chem. Int. Ed., 2009, 48, 3627 – 3631. (Designated by Editors as Hot paper)
7. Q. Sun, R. Collins, S. Huang, L. Holmberg-Schiavone, G. S. Anand, C.-H Tan, S. van-den-Berg, L.-W. Deng, P. K. Moore, T. Karlberg and J. Sivaraman. Structures of human cystathionine -gamma-Lyase reveal new insights into the mechanism of H2S production, J. Bio. Chem., 2009, 284, 3076 – 3085.
8. L. Li, M. Salto-Tellez, C.-H. Tan, M. Whiteman, P. K. Moore. GYY4137, A novel hydrogen sulfide releasing molecule, protects against endotoxic shock in the rat, Free Radical Biology & Medicine, 2009, 47, 103 – 113.
9. T. Zhou, X. Li, M. T. T. Ng, Y. Wang, N. M. Quek, J. Luo, W. Yuan, C.-H. Tan, H. Zeng, T. Li. Synthesis and characterization of circular structures of i-Motif tagged with Fluoresceins Bioconjugate Chem., 2009, 20, 644 – 647.
10. X. Fu, W.-T. Loh, Y. Zhang, T. Chen, H. Liu, J. Wang, and C.-H. Tan, Chiral guanidinium salt catalyzed enantioselective Phospha-Mannich reactions, Angew. Chem. Int. Ed., 2009, 40, 7387 – 7390. (Highlighted by Synfacts 2009, 11, 1281-1281; contributors: Benjamin List, Lars Ratjen)
11. S. Lin, D. Leow, K.-W. Huang, C.-H. Tan. Enantioselective protonation of itaconimides with thiols and insights into the rotational kinetics of the axially chiral C–N bond, Chem. Asian J., 2009, 4, 1741 – 1744.
2008
1. J. Shen and C.-H Tan, Brønsted-Acid and Brønsted-Base catalyzed Diels–Alder reactions, Org. Biomol. Chem., 2008, 6, 3229 – 3236. (Invited)
2. H. Liu, Y. Pan and C.-H. Tan, Sodium nitrite (NaNO2) catalysed iodo-cyclisation of alkenes and alkynes using molecular oxygen. Tetrahedron Let., 2008, 49, 4424 – 4426.
3. D. Leow, S. Lin, S. K. Chittimalla, X. Fu and C.-H. Tan, Enantioselective protonations catalyzed by chiral bicyclic guanidine, Angew. Chem. Int. Ed. Eng., 2008, 47, 5641 – 5645. (Highlighted by Synfacts 2008, 9, 0933-0933; contributors: Benjamin List, Frank Lay)
4. J. Xu, X. Fu, R. Low, Y.-P. Goh, Z. Jiang and C.-H. Tan, Tandem conjugate Addition-Elimination reaction promoted by Chiral Pyrrolidinyl Sulphonamide (CPS), Chem. Commun., 2008, 5526 – 5528. (Highlighted by Douglass F. Taber, Org. Chem. Highlights 2009, August 10.)
5. Z. Jiang, W. Ye, Y. Yang and C.-H. Tan, Rate acceleration of triethylamine-mediated guanidine-catalyzed enantioselective Michael reaction, Adv. Synth. Cat., 2008, 350, 2345 – 2351.
6. J. Shen and C.-H. Tan, Anthrone-Derived NHPI analogues as catalysts in reactions using oxygen as an oxidant, Org. Biomol. Chem., 2008, 6, 4096 – 4098.
7. Y. Wang, M. T. T. Ng, T. Zhou, X. Li, C.-H. Tan and T. Li, C3-Spacer-Containing circular oligonucleotides as inhibitors of Human Topoisomerase I. Bioorg. and Med. Chem. Let., 2008, 18, 3597 – 3602.
8. L. Li, M. Whiteman, Y. Y. Guan, K. L. Neo, Y. Cheng, S. W. L, Y. Zhao, R. Baskar, C.-H. Tan and P. K. Moore, Characterisation of a novel, water soluble hydrogen sulfide releasing molecule (GYY4137): new insights into the biology of hydrogen sulphide, Circulation, 2008, 117, 2351 – 2360.
9. S. M. Ong, C. Zhang, Y. C. Toh, S. H. Kim, H. L. Foo, C.-H. Tan, D. van Noort, S. Park and H. Yu, A gel-free 3D microfluidic cell culture system, Biomaterials, 2008, 29, 3237 – 3244.
10. R.-S. Liu, V. Drozd, N. Bagkar, C.-C. Shen, I. Baginskiy, C.-H. Chen and C.-H. Tan. Direct white light phosphor based on metallorganic coordination extended networks for UV-light-emitting diodes J. Electrochem. Soc., 2008, 155 (6), P71-P73.
11. D. Zhao, S.-M. Ong, Z. Yue, Y.-C. Toh, M. Khan, H. Yu, J.P. Chen, Z. Jiang, J. Shi and C.-H Tan, Dendrimer hydrazides as multivalent transient inter-cellular linkers, Biomaterials, 2008, 29, 3693 – 3702.
12. C.-H Tan and J. Shen. 2,3,5,6-Tetrahydro-2,6-bis(phenylmethyl)-1H-imidazo[1,2-a]imidazole, Electronic Encyclopedia of Reagents for Organic Synthesis (e-EROS), 2008, DOI: 10.1002/047084289X.rn00967. Article Online Posting Date: September 15, 2008. (Invited)
2007
1. Z. Jiang, Y. Zhang, W. Ye and C.-H. Tan, P-C Bond formation via direct and three-component conjugate addition catalyzed by 1,5,7-Triazabicyclo[4.4.0]dec-5-ene (TBD). Tetrahedron Let., 2007, 48, 51 – 54.
2. H. Liu and C.-H. Tan, Iodobenzene-catalysed iodolactonisation using sodium perborate monohydrate as oxidant. Tetrahedron Let., 2007, 48, 8220 – 8222.
3. X. Fu, Z. Jiang and C.-H. Tan, Bicyclic guanidine-catalyzed enantioselective Phospha-Michael reaction: Synthesis of chiral β-aminophosphine oxides and β-aminophosphines, Chem. Commun., 2007, 5058 – 5060.
4. W. Ye, Z. Jiang, Y. Zhao, Serena L. M. Goh, D. Leow, Y.-T. Soh and C.-H. Tan. Chiral bicyclic guanidine as a versatile Brønsted base catalyst for the enantioselective Michael reactions of dithiomalonates and β-keto thioesters, Adv. Synth. Cat., 2007, 349, 2454 – 2458.
5. S.M. Ong, L. He, N.T.T. Linh, Y.H. Tee, T. Arooz, G.P. Tang, C.H. Tan and Yu H. Transient inter-cellular polymeric linker. Biomaterials, 2007, 28, 3656 – 3667.
2006
1. W. Ye, D. Leow, Serena L. M. Goh, C.-T. Tan, C.-H. Chian and C.-H. Tan. Chiral bicyclic guanidines: a concise and efficient aziridine-based synthesis. Tetrahedron Let., 2006, 47, 1007 – 1010.
2. J. Xu, Y. Guan, S. Yang, Y. Ng, G. Peh and C.-H. Tan, Chiral imidazoline promoted asymmetric Baylis-Hillman reaction. Chem. Asian J.,2006, 1, 724 – 729.
3. J. Shen, T. T. Nguyen, Y.-P. Goh, W. Ye, X. Fu, J. Xu and C.-H. Tan, Chiral bicyclic guanidine catalyzed enantioselective reactions of anthrones. J. Am. Chem. Soc., 2006, 128, 13692 – 13693.
2005
1. W. Ye, J. Xu, C.T. Tan and C.H.Tan. 1,5,7-Triazabicyclo[4.4.0]dec-5-ene (TBD) catalyzed Michael reactions. Tetrahedron Let., 2005, 46, 6875 – 6878.
1995 – 2003
1. R.B.Wang, C.M.Lim, C.H.Tan, B.K.Lim, K.Y.Sim and T.P.Loh. Ytterbium trifluoromethanesulfonate [Yb(OTf)3] promoted indium mediated allylation reactions of carbonyl-compounds in aqueous-media. Tetrahedron-Asymmetry, 1995, 6, 1825 – 1828.
2. N.Srikanth, C.H.Tan, S.C.Ng, T.P.Loh, L.L.Koh and K.Y.Sim. Synthesis of heterocyclic analogues of tamoxifen as potential antiestrogens. J Chem Res-S, 1997, 8, 274 – 275; J Chem Res-M, 1997, 1828 – 1849.
3. W.P.Hems, C.H.Tan, T.Stork, N.Feeder and A.B.Holmes. Intramolecular cyclisation of (Z)-N-4-alkenylnitrones and the effects of alkenyl substituents. Tetrahedron Let., 1999, 40, 1393 – 1396.
4. C.H.Tan, T.Stork, N.Feeder and A.B.Holmes. Stereoselective synthesis of the indolizidine core of the allopumiliotoxins. Tetrahedron Let., 1999, 40, 1397 – 1400.
5. Y.Kobayashi, C.H.Tan and Y.Kishi. Toward creation of a universal NMR database for stereochemical assignment: the case of 1,3,5-trisubstituted acyclic systems. Helv. Chim. Acta, 2000, 83, 2562 – 2571.
6. Y.Kobayashi, C.H.Tan and Y.Kishi. Stereochemical assignment of the C21-C38 portion of the Desertomycin/Oasomycin class of natural products via universal NMR databases: Prediction. Angew. Chem. Int. Ed. Eng., 2000, 39, 4279 – 4281.
7. C.H.Tan, Y.Kobayashi and Y.Kishi. Stereochemical assignment of the C21-C38 portion of the Desertomycin/Oasomycin class of natural products via universal NMR databases: Proof. Angew. Chem. Int. Ed. Eng., 2000, 39, 4282–4284.
8. C.H.Tan and A.B.Holmes. Total synthesis of allopumiliotoxin 323B'. Chem. Eur. J., 2001, 7, 1845 – 1854.
9. Y.Kobayashi, C.H.Tan and Y.Kishi. Toward creation of a universal NMR databases for stereochemical assignment: Complete structure of the Desertomycin/Oasomycin class of natural products, J. Am. Chem. Soc., 2001, 123, 2076 – 2078.
10. Y.Kobayashi, N.Hayashi, C.H.Tan and Y.Kishi. Toward the creation of NMR databases in chiral solvents for assignments of relative and absolute stereochemistry: Proof of concept. Org. Let., 2001, 3, 2245 – 2248.D.H.Ryu, C.H.Tan and R.R.Rando. Synthesis of (+), (-)-Neamine and their positional isomers as potential antibiotics. Bioorganic Med. Chem. Lett., 2003, 13, 901 – 903