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成果及论文

部分科研成果

2024:

134. Si-Yi Liu, Lu Fan, Zi-Qi Zhu*, and Feng Shi*, Brønsted Acid-Catalyzed Regioselective [5+1] Annulation for the Synthesis of Indole-Fused DihydrochromanesJ. Org. Chem. 202489(22), 16791–16803. DOI: 10.1021/acs.joc.4c02101

133. Jiang-Ning Yu, Yue Wang, Ji-Chen Yin, and Yang Wang*, Organoiodine Catalysed Intram olecular C-N bond Oxidative Coupling for the Synthesis of 3-Monosubstituted Oxindoles, Eur. J. Org. Chem. 2024, DOI:10.1002/ejoc.202400822


132. Yang WangJi-Chen YinYu-Wei ZhangYuzhe ZhangFeng Shi*, Hypervalent iodine-mediated regioselective dearomatization of non-activated arenes, Adv. Synth. Catal. 2024, DOI: 10.1002/adsc.202400852


131. Cheng-Cheng Tian, Dan Yang, Yu Liu, Wei Chen, Yuzhe Zhang* and Hong-Hao Zhang*, Synthesis of β-Amino Acid Derivatives via Photoredox-Catalyzed Radical Cross‐Coupling of Anilines with Diazo Compounds. Org. Chem. Front. 2024, 11, 6042-6047. DOI: 10.1039/D4QO01396D


130. Tian-Zhen Li, Shu-Fang Wu, Ning-Yi Wang, Chen-Shengping Hong, Yu-Chen Zhang,and Feng Shi*, Catalytic Atroposelective Synthesis of N−N Axially Chiral Indolylamides. J. Org. Chem. 2024, DOI: 10.1021/acs.joc.4c01489


129. Ping Wu, Wen-Tao Zhang, Ji-Xiang Yang, Xian-Yang Yu, Shao-Fei Ni,* Wei Tan* and Feng Shi*, Synthesis of Alkene Atropisomers with Multiple Stereogenic Elements via Catalytic Asymmetric Rearrangement of 3- Indolylmethanols. Angew. Chem. Int. Ed. 2024, e202410581, DOI: 10.1002/anie.202410581


128. Wei Tan,Xin-Yue Wu, and Feng Shi*, Catalytic Atroposelective Construction of Furan-Based Axially Chiral Scaffolds. ChemCatChem 2024, DOI: 10.1002/cctc.202401022


127.Si-Jia Liu, Tian-Zhen Li, Ning-Yi Wang, Qi Cheng, Yinchun Jiao,* Yu-Chen Zhang,*  and Feng Shi*, Catalytic Asymmetric Formal (2 + 3) Cycloaddition Involving Methyl-Substituted 2-Indolylmethanols, Org. Chem. Front. 2024, 11, 4812-4819. DOI: 10.1039/D4QO01047G


126. Yue Wang, Jiang-Ning Yu, Yang Wang,* and Feng Shi*, Intermolecular α‑Functionalization of Benzylamides with N‑Nucleophiles via Oxidative Umpolung: Synthesis of Tetrasubstituted 3,3′-Oxindoles, Org. Lett. 202426(28), 6041-6046. DOI:10.1021/acs.orglett.4c02167


125. Bo-Wen Lai, Shi-Yu Qu, Yu-Xian Yin, Rui Li, Kuiyong Dong*, and Feng Shi*, Cooperative Catalysis-Enabled (4 + 3) Cycloaddition of 2-Indolylmethanols with In Situ-Generated ortho-Naphthoquinone Methides, J. Org. Chem. 202489(14),  10197–10211. DOI: 10.1021/acs.joc.4c01080

124.Zi-Qi Zhu,* Tian-Zhen Li, Si-Jia Liu, and Feng Shi*, Advances in Organocatalytic Asymmetric [3+3] Cycloadditions Synthesis of Chiral Six-Membered (Hetero)cyclic Compounds, Org. Chem. Front. 2024, DOI: 10.1039/D4QO00515E


123. Shuang Yang, Jia-Bo Huang, Da-Hua Wang, Ning-Yi Wang, Yu-Yu Chen, Xin-Yan Ke, Hao Chen, Shao-Fei Ni,* Yu-Chen Zhang,* and Feng Shi*, Catalytic Asymmetric Diastereodivergent Synthesis of 2‑Alkenylindoles Bearing both Axial and Central Chirality. Precis. Chem. 2024, 2(5), 208–220. DOI: 10.1021/prechem.4c00008

 

122.Tian-Zhen Li, Si-Jia Liu, Shu-Fang Wu, Qi Cheng, Qun Chen,Yinchun Jiao,Yu-Chen Zhang* & Feng Shi*, Catalytic Asymmetric (3 + 3) Cycloaddition between Different 2-Indolylmethanols, Science China Chemistry 2024, DOI:10.1007/s11426-023-1927-3


121. Jing-Yi Wang, Cong-Hui Gao, Cheng Ma, Xin-Yue Wu, Shao-Fei Ni,* Wei Tan* and  Feng Shi*, Design and Catalytic Asymmetric Synthesis of Furan-Indole  Compounds Bearing both Axial and Central Chirality. Angew. Chem., Int. Ed. 2024, 63 e202316454. DOI: 10.1002/anie.202316454


120. Hong-Hao Zhang,* Tian-Zhen Li, Si-Jia Liu, and Feng Shi*, Catalytic Asymmetric Synthesis of Atropisomers Bearing Multipl Chiral Elements: An Emerging Field, Angew. Chem., Int. Ed. 2024, 63e202311053. DOI: 10.1002/anie.202311053


2023:

119. Shu-Fang Wu, Guo-Ke Zhang, Xue Wang, Zhuo-Jing He, Yu-Chen Zhang,and Feng Shi*, Organocatalytic Diastereoselective (4 + 1) Cycloaddition of o‑Hydroxyphenyl-Substituted Secondary Phosphine Oxides, J. Org. Chem. 2023, 88(23), 16497-16510. DOI: 10.1021/acs.joc.3c01990


118. Guo-Ke Zhang, Shu-Fang Wu, Chen Zhong, Yu-Qi Liu, Da-Hua Wang*Yu-Chen Zhang*and Feng Shi*, Copper-Catalyzed α,β-Regioselective (2+4) Cycloaddition of Propargylic Esters, Eur. J. Org. Chem. 2023, 26(46),  e202300802. DOI:10.1002/ejoc.202300802


117. Lei Yu, Ran Xu, Yan-Yi Yao, Yu Lu, Fei-Yang Liu, Wei Tan* and Feng Shi*, Organocatalytic (Z/E)‑Selective Synthesis of 3‑Vinylnaphthofurans via a Formal (3 + 2) Cycloaddition, J. Org. Chem. 202388(6), 3474−3486. DOI:10.1021/acs.joc.2c02641


116. Cong-Hui Gao, Lei Yu, Xin-Yue Wu, Hong-Lin Wan, Wei Tan* and Feng Shi*, Brønsted Acid–Catalyzed Tandem Reaction of 1,4-Enediones with 2-Naphthols: Synthesis of 2-Furylmethylnaphthalenes, Asian J. Org. Chem. 2023, 12(9), e202300231. DOI:10.1002/ajoc.202300231


115. Shuang Yang, Ning-yi Wang, Qing-qing Hang, Yu-chen Zhang*Feng Shi*, Advances in Catalytic Asymmetric Reactions Involving o-Hydroxyphenyl Substituted p-Quinone Methides, Acta Chim. Sinica 202381(7)793-808DOI:10.6023/A23040192


114. Jia-Yi Zhang, Jia-Yi Chen, Cong-Hui Gao, Lei Yu, Shao-Fei Ni*, Wei Tan* and Feng Shi*, Asymmetric (4+n) Cycloadditions of Indolyldimethanols for the Synthesis of Enantioenriched Indole-Fused Rings, Angew. Chem. Int. Ed. 2023, 62(37),  e202305450. DOI:10.1002/anie.202305450


113. Hai-Qing Wang, Shuang YangYu-Chen Zhang*, Feng Shi*, Advances in Catalytic Asymmetric Reactions Involving o-Hydroxybenzyl Alcohols, Chin. J. Org. Chem. 202343(3), 974-999.  DOI:10.6023/cjoc202211022


112. Zhi-Han Chen, Tian-Zhen Li, Ning-Yi Wang, Xiao-Fang Ma, Shao-Fei Ni, Yu-Chen Zhang* and Feng Shi*, Organocatalytic Enantioselective Synthesis of Axially Chiral NN'-Bisindoles, Angew. Chem. Int. Ed. 2023, 62(15), e202300419. DOI:10.1002/anie.202300419



111. Wei Tan*, Jia-Yi Zhang, Cong-Hui Gao, Feng Shi*, Progress in Organocatalytic Asymmetric (4 + 3) Cycloadditions for theEnantioselective Construction of Seven-membered Rings, Sci. China Chem. 2023, 66, 966-992.pages966–992 DOI:10.1007/s11426-022-1471-2


110. Hai-Qing Wang§, Shu-Fang Wu§, Jun-Ru Yang, Yu-Chen Zhang*, and Feng Shi*, Design and Organocatalytic Asymmetric Synthesis of Indolyl-Pyrroloindoles Bearing Both Axial and Central Chirality, J. Org. Chem. 202388(12), 7684–7702. DOI:10.1021/acs.joc.2c02303


109. Yi-Cheng Shi, Xin-Yu Yan, Ping Wu, Song Jiang, Ran Xu, Wei Tan* and Feng Shi*, Design and Application of m-Hydroxybenzyl Alcohols in Regioselective (3+3) Cycloadditions of 2-Indolymethanols, Chin. J. Chem. 2023, 41(1), 27-36. DOI:10.1002/cjoc.202200503


108. Ping Wu, Lei Yu, Cong-Hui Gao, Qi Cheng, Shuang Deng, Yinchun Jiao*, Wei Tan* and  Feng Shi*, Design and Synthesis of Axially Chiral Aryl-Pyrroloindoles via the Strategy of Organocatalytic Asymmetric (2+3) Cyclization, Fundam. Res. 20233(2), 237-248. DOI:10.1016/j.fmre.2022.01.002



2022:

107. Hong-Hao Zhang and Feng Shi*, Advances in Catalytic Asymmetric Reactions Using 2-Indolylmethanols as Platform Molecules, Chin. J. Org. Chem. 2022, 42(10), 3351-3372. DOI:10.6023/cjoc202203018


106. Yang Wang*, Zheng-Guang Wu, Feng Shi*,  Advances in catalytic enantioselective synthesis of chiral helicenes and helicenoids, Chem. Catalysis 2022, 2(11), 3077-3111. DOI:10.1016/j.checat.2022.10.011


105. Hong-Hao Zhang and Feng Shi*, Organocatalytic Atroposelective Synthesis of Indole Derivatives Bearing Axial Chirality: Strategies and Applications, Acc. Chem. Res. 2022, 55(18), 2562-2580. DOI:10.1021/acs.accounts.2c00465


104. Shuang Yang, Hai-Qing Wang, Jun-Nan Gao, Wen-Xin Tan, Yu-Chen Zhang*, Feng Shi*, Lewis Acid-Catalyzed (3+2) Cycloaddition of 2-Indolylmethanol with β,γ-Unsaturated α-Ketoesters, Eur. J. Org. Chem. 20222022(35), e202200878. DOI:10.1002/ejoc.202200878


103. Qing-Qing Hang, Shu-Fang Wu, Shuang Yang, Xue Wang, Zhen Zhong, Yu-Chen Zhang* & Feng Shi*, Design and Catalytic Atroposelective Synthesis of Axially Chira Isochromenone-Indoles, Science China Chemistry 202265, 1929-1937. DOI:10.1007/s11426-022-1363-y


102. Feng-Tao Sheng, Shuang Yang, Shu-Fang Wu, Yu-Chen Zhang*Feng Shi*, Catalytic Asymmetric Synthesis of Axially Chiral 3,3'-Bisindoles by Direct Coupling of Indole Rings, Chin. J. Chem. 2022, 40(18), 2151-2160. DOI: 10.1002/cjoc.202200327


101Jing-Yi Wang, Shuming Zhang, Xian-Yang Yu, Yu-Hao Wang, Hong-Lin Wan, Shu Zhang*, Wei Tan*, Feng Shi*, Organocatalytic Asymmetric Synthesis of Bioactive Hexahydropyrrolo[2,3-b] Indole-containing Tetrasubstituted Allenes Bearing Multiple Chiral Elements, Tetrahedron Chem. 2022, 1, 100007. DOI: 10.1016/j.tchem.2022.100007


100. Ke-Wei Chen, Zhi-Han Chen, Shuang Yang, Shu-Fang Wu, Yu-Chen Zhang* and Feng Shi*, Organocatalytic Atroposelective Synthesis of N–N Axially Chiral Indoles and Pyrroles by De Novo Ring Formation, Angew. Chem. Int. Ed. 202261(17), e202116829. DOI:10.1002/anie.202116829


99. Si-Jia Liu, Zhi-Han Chen, Jia-Yi Chen, Shao-Fei Ni*, Yu-Chen Zhang* and Feng Shi*Rational Design of Axially Chiral Styrene-Based Organocatalysts and Their Application in Catalytic Asymmetric (2+4) Cyclizations, Angew. Chem. Int. Ed. 202261(7), e202112226. DOI:10.1002/anie.202112226


2021:

98. Jing-Yi Wang, Meng Sun, Xian-Yang Yu, Yu-Chen Zhang, Wei Tan* and Feng Shi*Atroposelective Construction of Axially Chiral Alkene‐Indole Scaffolds via Catalytic Enantioselective Addition Reaction of 3‐Alkynyl‐2‐indolylmethanolsChin. J. Chem. 2021, 39, 2163-2171. DOI:10.1002/cjoc.202100214


97. Man-Su Tu, Ke-Wei Chen, Ping Wu, Yu-Chen Zhang*, Xiao-Qin Liu* and Feng Shi*, Advances in organocatalytic asymmetric reactions of vinylindoles: powerful access to enantioenriched indole derivatives, Org. Chem. Front. 20218, 2643-2672. DOI: 10.1039/d0qo01643h


96. Tian-Zhen Li, Si-Jia Liu, Yu-Wen Sun, Shuang Deng, Wei Tan, Yingchun Jiao*Yu-Chen Zhang* and Feng Shi*, Regio- and Enantioselective (3+3) Cycloaddition of Nitrones with 2-Indolylmethanols Enabled by Cooperative OrganocatalysisAngew. Chem. Int. Ed. 2021, 60(5), 2355-2363. DOI:10.1002/anie.202011267


95. Xiao Wan, Meng Sun, Jing-Yi Wang, Lei Yu, Qiong Wu*, Yu-Chen Zhang* and Feng Shi*Regio- and Enantioselective Ring-Opening Reaction of Vinylcyclopropanes with Indoles under Cooperative Catalysis, Org. Chem. Front. 2021, 8, 212-223DOI:10.1039/d0qo00699h



2020:

94. Feng-Tao Sheng, Jing-Yi Wang, Wei Tan*,  Yu-Chen Zhang* and Feng Shi*, Progresses in Organocatalytic Asymmetric Dearomatization Reactions of Indole Derivatives, Org. Chem. Front. 2020, 7, 3967-3998. DOI:10.1039/D0QO01124J



93. Chun Ma, Feng-Tao Sheng, Hai-Qing Wang, Shuang Deng, Yu-Chen Zhang*, Yin-Chun Jiao, Wei Tan* and Feng Shi*, Atroposelective Access to Oxindole-Based Axially Chiral Styrenes via the Strategy of Catalytic Kinetic Resolution, J. Am. Chem. Soc. 2020, 142(37), 15686-15696. DOI: 10.1021/jacs.0c00208



92. Ji Zhou,  Tian-Zhen Li, Yu-Wen Sun, Bai-Xiang Du, Wei Tan* and Feng Shi*, Chiral Brønsted Acid-Catalyzed Asymmetric 1,4-Addition of Benzofuran-Derived Azadienes with 3-Substituted Indoles, ChemCatChem 2020, 12(19), 4862-4870DOI: 10.1002/cctc.202000810


91. Ye-Xin Wang, Yi-Nan Lu, Lin-Lin Xu, Feng-Tao Sheng, Jin-Peng Zhang*, Wei Tan* and Feng Shi*, Application of Benzofuran-Derived Azadienes as Two-Carbon Building Blocks in Annulations: Chemo- and Diastereoselective Construction of Spiro-Benzofuran Scaffolds, Synthesis 202052(20), 2979-2986DOI: 10.1055/s-0040-1707205


90. Ke-Wei Chen, Zhao-Shan Wang, Ping Wu, Xin-Yu Yan, Shu Zhang*, Yu-Chen Zhang* and Feng Shi*, Catalytic Asymmetric Synthesis of 3,3’-Bisindoles Bearing Single Axial Chirality, J. Org. Chem. 2020, 85(15), 10152-10166. DOI: 10.1021/acs.joc.0c01528


89. Si-Jia Zhou, Meng Sun, Jing-Yi Wang, Xian-Yang Yu, Han Lu, Yu-Chen Zhang* and Feng Shi*, Metal-Catalyzed Regiospecific (4+3) Cyclization of 2-Indolylmethanols with ortho-Quinone Methides, Eur. J. Org. Chem. 20202020(28), 4301-4308DOI: 10.1002/ejoc.202000693


88. Qing-Qing Hang, Si-Jia Liu, Lei Yu, Ting-Ting Sun, Yu-Chen Zhang*, Guang-Jian Mei* and Feng Shi*, Design and Application of Indole-Based Allylic Donors for Pd‐Catalyzed Decarboxylative Allylation Reactions, Chin. J. Chem. 2020, 38(12), 1612-1618. DOI: 10.1002/cjoc.202000104


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87. Tian-Zhen Li, Si-Jia Liu, Wei Tan* and Feng Shi*, Catalytic Asymmetric Construction of Axially Chiral Indole-Based Frameworks: An Emerging Area, Chem. Eur. J. 202026(68), 15779-15792DOI: 10.1002/chem.202001397

                                                                              

86. Cong-Shuai Wang, Tian-Zhen Li, Si-Jia Liu, Yu-Chen Zhang,Shuang Deng, Yinchun Jiao* and Feng Shi*, Axially Chiral Aryl-Alkene-Indole Framework: A Nascent Member of the Atropisomeric Family and Its Catalytic Asymmetric Construction, Chin. J. Chem. 202038, 543-552. DOI: 10.1002/cjoc.202000131


85.  Feng-Tao Sheng, Zhi-Min Li, Yi-Zhu Zhang, Li-Xing Sun, Yu-Chen Zhang, Wei Tan*, Feng Shi*, Atroposelective Synthesis of 3,3’-Bisindoles Bearing Axial and Central Chirality: Using Isatin-Derived Imines as Electrophiles, Chin. J. Chem. 2020,  38, 583-589. DOI: 10.1002/cjoc.202000022


84. Yu-Chen Zhang, Fei Jiang, Feng Shi*, Organocatalytic Asymmetric Synthesis of Indole-Based Chiral Heterocycles: Strategies, Reactions, and Outreach, Acc. Chem. Res. 2020, 53(2), 425-446. DOI: 10.1021/acs.accounts.9b00549


2019:

83. Fei Jiang, Ke-Wei Chen, Ping Wu, Yu-Chen Zhang*, Yinchun Jiao, Feng Shi*, A Strategy for Synthesizing Axially Chiral Naphthyl-Indoles: Catalytic Asymmetric Addition Reactions of Racemic Substrates, Angew. Chem. Int. Ed. 201958 (42), 15104-15110.

 

82. Meng Sun, Chun Ma, Si-Jia Zhou, Sai-Fan Lou, Jian Xiao, Yinchun Jiao*, Feng Shi*, Catalytic Asymmetric (4+3) Cyclizations of In Situ Generated ortho-Quinone Methides with 2-Indolylmethanols, Angew. Chem. Int. Ed. 201958(26), 8703-8708.


 

81. Chun Ma, Fei Jiang, Feng-Tao Sheng, Yinchun Jiao, Guang-Jian Mei, Feng Shi*, Design and Catalytic Asymmetric Construction of Axially Chiral 3,3’-Bisindole Skeletons, Angew. Chem., Int. Ed. 2019, 58(10), 3014-3020.

 


80. Can Li, Cong-Shuai Wang, Tian-Zhen Li, Guang-Jian Mei, Feng Shi*, Brønsted Acid-Catalyzed (4 + 3) Cyclization of N,N’‑Cyclic Azomethine Imines with Isatoic Anhydrides, Org. Lett. 201921(3), 598−602.

 

79. Meng Sun, Xiao Wan, Si-Jia Zhou, Guang-Jian Mei, Feng Shi*, Iridium and  Brøsted acid cooperatively catalyzed chemodivergent and stereoselective reactions of vinyl benzoxazinones with azlactones, Chem. Commun. 201955(9), 1283-1286.

 

78. Cong-Shuai Wang, Tian-Zhen Li, Yu-Chun Cheng, Ji Zhou, Guang-Jian Mei, Feng Shi*, Catalytic Asymmetric [4+1] Cyclization of Benzofuran-Derived Azadienes with 3-Chlorooxindoles, J. Org. Chem. 201984(6), 3214−3222.


2018:

77. Chun Ma, Jia-Yu Zhou, Yi-Zhu Zhang, Guang-Jian Mei*, Feng Shi*, Catalytic Asymmetric [2+3] Cyclizations of Azlactones with Azonaphthalenes, Angew. Chem., Int. Ed. 201857(19), 5398-5402

 

76. Fei Jiang, Fu-Ru Yuan, Li-Wen Jin, Guang-Jian Mei*, Feng Shi*, Metal-Catalyzed (4 + 3) Cyclization of Vinyl Aziridines with para-Quinone Methide DerivativesACS Catal. 20188(11), 10234–10240

 

75. Yi-Nan Lu, Chun Ma, Jin-Ping Lan, Caiqiang Zhu, Yu-Jia Mao, Guang-Jian Mei, Shu Zhang*, Feng Shi*Catalytic enantioselective and regioselective substitution of 2,3-indolyldimethanols with enaminones, Org. Chem. Front. 20185(18), 2657-2667.

 


74. Jia-Le Wu, Jing-Yi Wang, Ping Wu, Jin-Rong Wang, Guang-Jian Mei, Feng Shi*, Diastereo- and enantioselective construction of chiral cyclopenta[b]indole framework via a catalytic asymmetric tandem cyclization of 2-indolymethanols with 2-naphthols, Org. Chem. Front. 20185(9), 1436-1445.

 

73. Cong-Shuai Wang, Yu-Chun Cheng, Ji Zhou, Guang-Jian Mei, Shu-Liang Wang*, Feng Shi*, Metal-Catalyzed Oxa-[4+2] Cyclizations of Quinone Methides with Alkynyl Benzyl Alcohols, J. Org. Chem. 201883(22), 13861−13873.

 


72. Meng Sun, Zi-Qi Zhu, L. Gu, Xiao Wan, Guang-Jian Mei, Feng Shi*, Catalytic Asymmetric Dearomative [3 + 2] Cycloaddition of Electron-Deficient Indoles with All-Carbon 1,3-Dipoles, J. Org. Chem. 201883(4), 2341−2348.

 

71. Guang-Jian Mei*, Shao-Li Xu, Wen-Qin Zheng, Chen-Yu Bian, Feng Shi*, [4 + 2] Cyclization of para-Quinone Methide Derivatives with Alkynes, J. Org. Chem. 201883(3), 1414−1421.

 

70. Lin-Zhi Li, Cong-Shuai Wang, Wei-Feng Guo, Guang-Jian Mei*, Feng Shi*, Catalytic Asymmetric [4+2] Cycloaddition of in Situ Generated o‑Quinone Methide Imines with o‑Hydroxystyrenes: Diastereo- and Enantioselective Construction of Tetrahydroquinoline Frameworks, J. Org. Chem. 201883(2), 614−623.

 

69.Meng-Meng Xu, Hai-Qing Wang, Yu-Jia Mao, Guang-Jian Mei, Shu-Liang Wang, Feng Shi*, Cooperative Catalysis-Enabled Asymmetric alfa-Arylation of Aldehydes Using 2-Indolylmethanols as Arylation Reagents, J. Org. Chem. 201883(9), 5027-5034.

 

68. Jing-Yi Wang, Ping Wu, Jia-Le Wu, Guang-Jian Mei*, Feng Shi*, Chemodivergent Tandem Cyclizations of 2-Indolylmethanols with Tryptophols: C-N versus C-C Bond Formation, J. Org. Chem. 201883(11), 5931-5946.

 

67. Can Li, Dan-Ni Xu, Chun Ma, Guang-Jian Mei, Feng Shi*,  Diastereo- and Enantioselective Construction of Dihydrobenzo[e]indole Scaffolds via Catalytic Asymmetric [3+2] Cycloannulations, J. Org. Chem. 201883(16), 9190-9200.

 

66. Fei Jiang, Gui-Zhen Luo, Zi-Qi Zhu, Cong-Shuai Wang, Guang-Jian Mei, Feng Shi*,  Application of Naphthylindole-Derived Phosphines as Organocatalysts in [4 + 1] Cyclizations of o-Quinone Methides with Morita-Baylis-Hillman Carbonates, J. Org. Chem. 201883(17), 10060-10069.

 

65. Cong-Shuai Wang, Jia-Le Wu, Can Li, Lin-Zhi Li, Guang-Jian Mei, Feng Shi*, Design of C3-Alkenyl-Substituted 2-Indolylmethanols for Catalytic Asymmetric Interrupted Nazarov-Type Cyclization, Adv. Synth. Catal. 2018360(5), 846-851.

 

64. Ting Zhang, Chun Ma, Jia-Yu Zhou, Guang-Jian Mei, Feng Shi*, Application of Homophthalic Anhydrides as 2C Building Blocks in Catalytic Asymmetric Cyclizations of ortho-Quinone Methides: Diastereo- and Enantioselective Construction of Dihydrocoumarin Frameworks, Adv. Synth. Catal. 2018360(6), 1128-1137.

 

63. Hai-Qing Wang, Meng-Meng Xu, Ying Wan, Yu-Jia Mao, Guang-Jian Mei*,  Feng Shi*,  Application of 7-Indolylmethanols in Catalytic Asymmetric Arylations with Tryptamines: Enantioselective Synthesis of 7-indolylmethanes, Adv. Synth. Catal. 2018360(9), 1850-1860.

 

62. Zi-Qi Zhu, Lei Yu, Meng Sun, Guang-Jian Mei*, Feng Shi*,  Regioselective [3+3] Cyclization of 2-Indolymethanols with Vinylcyclopropanes via Metal Catalysis, Adv. Synth. Catal. 2018, 360(16), 3109-3116.

 

61. Xiao-Li Jiang, Shu-Fang Wu, Jin-Rong Wang, Guang-Jian Mei, Feng Shi*Catalytic Asymmetric [4+2] Cyclization of para-Quinone Methide Derivatives with 3-Alkyl-2-vinylindoles Adv. Synth. Catal. 2018360(21), 4225-4235.

 


60. Yi-Nan Lu, Jin-Ping Lan, Yu-Jia Mao, Ye-Xin Wang, Guang-Jian Mei*, Feng Shi*, Catalytic Asymmetric de novo Construction of Dihydroquinazolinone Scaffolds via Enantioselective Decarboxylative [4+2] Cycloadditions, Chem. Commun. 201854(96), 13527-13530.

 


59. Guang-Jian Mei, Feng Shi*, Catalytic asymmetric synthesis of spirooxindoles: recent developments, Chem. Commun. 201854(50), 6607-6621. (invited feature article)

 

58. Chun Ma, Jia-Yu Zhou, Yi-Zhu Zhang, Yinchun Jiao, Guang-Jian Mei, Feng Shi*, Synergistic-Catalysis-Enabled Reaction of 2-Indolymethanols with Oxonium Ylides for the Construction of 3-Indolyl-3-Alkoxy Oxindole Frameworks, Chemistry - An Asian Journal201813(17), 2549-2558. (invited)

 


2017

57. Hong-Hao Zhang, Cong-Shuai Wang, Can Li, Guang-Jian Mei, Yuxue Li*, Feng Shi*, Design and Enantioselective Construction of Axially Chiral Naphthyl-Indole Skeletons, Angew. Chem., Int. Ed. 201756(1), 116 –121.


56. Fei Jiang, Dan Zhao, Xue Yang, Fu-Ru Yuan, Guang-Jian Mei, Feng Shi*, Catalyst-Controlled Chemoselective and Enantioselective Reactions of Tryptophols with Isatin-Derived Imines, ACS Catal. 20177(10), 6984-6989.

 

55. Chun Ma, Ting Zhang, Jia-Yu Zhou, Guang-Jian Mei, Feng Shi*, Catalytic asymmetric chemodivergent arylative dearomatization of tryptophols, Chem. Commun. 201753(89), 12124-12127.

 

54. Guang-Jian Mei, Zi-Qi Zhu, Jia-Jia Zhao, Chen-Yu Bian, Jie Chen, Ruo-Wei Chen, Feng Shi*, Brønsted acid-catalyzed stereoselective [4+3] cycloadditions of ortho-hydroxybenzyl alcohols with N,N’-cyclic azomethine imines, Chem. Commun. 201753(18), 2768-2771.

 


53. Guang-Jian Mei, Zi-Qi Zhu, Jia-Jia Zhao, Chen-Yu Bian, Jie Chen, Ruo-Wei Chen, Feng Shi*,  A catalytic asymmetric construction of a tetrahydroquinoline-based spirooxindole framework via a diastereoand enantioselective decarboxylative [4+2] cycloaddition, Chem. Commun. 201753(72), 10030-10033.

 

52. Guang-Jian Mei*, Chen-Yu Bian, Guo-Hao Li, Shao-Li Xu, Wen-Qin Zheng, and Feng Shi*, Catalytic Asymmetric Construction of the Tryptanthrin Skeleton via an Enantioselective Decarboxylative [4 + 2] Cyclization, Org. Lett. 201719(12), 3219-3222.

 


51. Zi-Qi Zhu, Yang Shen, Jin-Xi Liu, Ji-Yu Tao, and Feng Shi*, Enantioselective Direct α‑Arylation of Pyrazol-5-ones with 2‑Indolylmethanols via Organo-Metal Cooperative Catalysis, Org. Lett. 201719(7), 1542-1545.

 

50. Meng-Meng Xu, Hai-Qing Wang, Ying Wan, Guofeng He, Jingjing Yan, Shu Zhang*, Shu-Liang Wang, Feng Shi*, Catalytic asymmetric substitution of orthohydroxybenzyl alcohols with tetronic acid-derived enamines: enantioselective synthesis of tetronic acid-derived diarylmethanes, Org. Chem. Front. 20174(3), 358-368.

 

49. Zi-Qi Zhu, Lei Yin, Yang Wang, Yang Shen, Can Li, Guang-Jian Mei*, Feng Shi*, Diastereo- and enantioselective construction of biologically important pyrrolo[1,2-a]indole scaffolds via catalytic asymmetric [3 + 2] cyclodimerizations of 3-alkyl-2-vinylindoles, Org. Chem. Front. 20174(1), 57–68.

 

48. Jia-Le Wu, Jing-Yi Wang, Ping Wu, Guang-Jian Mei, Feng Shi*, Catalytic asymmetric C2-nucleophilic substitutions of C3-substituted indoles with ortho-hydroxybenzyl alcohols, Org. Chem. Front. 20174(12), 2465-2479.

 

47. Ying-Ying He, Xiao-Xue Sun, Guo-Hao Li, Guang-Jian Mei*, Feng Shi*, Substrate-Controlled Regioselective Arylations of 2-Indolylmethanols with Indoles: Synthesis of Bis(indolyl)methane and 3,3'-Bisindole Derivatives, J. Org. Chem. 201782(5), 2462-2471.

 

46. Guang-Jian Mei, Feng Shi*, Indolylmethanols as Reactants in Catalytic Asymmetric Reactions, J. Org. Chem. 2017, 82(15), 7695-7707. (invited Synopsis)

 

45. Meng-Meng Xu, Hai-Qing Wang, Ying Wan, Shu-Liang Wang, Feng Shi*, Enantioselective Construction of Cyclopenta[b]indole Scaffolds via the Catalytic Asymmetric [3 + 2] Cycloaddition of 2-Indolylmethanols with p-Hydroxystyrenes, J. Org. Chem. 201782(19), 10226-10233.

 


44. Xiao-Xue Sun, Can Li, Ying-Ying He, Zi-Qi Zhu, Guang-Jian Mei, Feng Shi*, Catalytic Asymmetric [3+3] Cycloaddition of Azomethine Ylides with C3-Substituted 2-Indolylmethanols, Adv. Synth. Catal. 2017359(15), 2660-2670.

 

43. Xiao-Li Jiang, Si-Jia Liu, Yu-Qi Gu, Guang-Jian Mei*, Feng Shi*, Catalytic Asymmetric [4+1] Cyclization of ortho-Quinone Methides with 3-Chlorooxindoles, Adv. Synth. Catal. 2017359(19), 3341-3346.

 

2016

42. Jia-Jia Zhao, Man Tang, Hong-Hao Zhang, Meng-Meng Xu, Feng Shi*, Bronsted acid-catalyzed chemodivergent reactions of ortho-mercaptobenzyl alcohols with 3-alkyl-2-vinylindoles and styrenes: [5+2] cyclization versus hydroxysulfenylation, Chem. Commun. 201652(35), 5953-5956.

 

41. Xiao-Xue Sun, Hong-Hao Zhang, Guo-Hao Li, Meng, Li; Feng Shi*, Diastereo- and enantioselective construction of an indole-based 2,3-dihydrobenzofuran scaffold via catalytic asymmetric [3+2] cyclizations of quinone monoimides with 3-vinylindoles, Chem. Commun. 201652(14), 2968-2971.

 

40. Yue-Ming Wang, Hong-Hao Zhang, Can Li, Tao Fan, Feng Shi*, Catalytic asymmetric chemoselective 1,3-dipolar cycloadditions of an azomethine ylide with isatin-derived imines: diastereo- and enantioselective construction of a spiro[imidazolidine-2,3'-oxindole] framework, Chem. Commun. 201652(9), 1804-1807.

 

39. Cong-Shuai Wang, Tao Fan, Hong-Hao Zhang, Can Li, Yang Shen, Guang-Jian Mei*, Feng Shi*, Gallium Bromide-Promoted Dearomative Indole Insertion in 3-Indolylmethanols: Chemoselective and (Z/E)-Selective Synthesis of 3,3'-Bisindole Derivatives, J. Org. Chem. 201681(23), 11734-11742.

 

38. Yu-Chen Zhang, Qiu-Ning Zhu, Xue Yang, Lu-Jia Zhou, Feng Shi*, Merging Chiral Bronsted Acid/Base Catalysis: An Enantioselective [4 + 2] Cycloaddition of o-Hydroxystyrenes with Azlactones, J. Org. Chem. 201681(4), 1681-1688.

 

37. Jia-Le Wu, Bai-Xiang Du, Yu-Chen Zhang, Ying-Ying He, Jing-Yi Wang, Ping Wu, Feng Shi*, Diastereo- and Enantioselective Construction of Dihydroisocoumarin-Based Spirooxindole Frameworks via Organocatalytic Tandem Reactions, Adv. Synth. Catal. 2016358(17), 2777-2790.

 


36.  Lei Yin, Yang Wang, Meng Sun, Feng Shi*, Bronsted Acid-Catalyzed [3+2] Cyclodimerization of 3-Alkyl- 2-vinylindoles Leading to the Diastereoselective Construction of a Pyrroloindole Framework, Adv. Synth. Catal. 2016358(7), 1093-1102.

 


35. Tao Fan, Hong-Hao Zhang, Can Li, Yang Shen, Feng Shi*, The Application of N-Protected 3-Vinylindoles in Chiral Phosphoric Acid-Catalyzed [3+2] Cyclization with 3-Indolylmethanols: Monoactivation of the Catalyst to Vinyliminium, Adv. Synth. Catal. 2016358(12), 2017-2031.

 

34.Lu-Jia Zhou, Yu-Chen Zhang, Fei Jiang, Guofeng He, Jingjing Yan, Han Lu*; Shu Zhang*; Feng Shi*, Enantioselective Construction of Cyclic Enaminone-Based 3-Substituted 3-Amino-2-oxindole Scaffolds via Catalytic Asymmetric Additions of Isatin-Derived Imines, Adv. Synth. Catal. 2016358(19), 3069-3083.

 

33. Zi-Qi Zhu, Yang Shen, Xiao-Xue Sun, Ji-Yu Tao, Jin-Xi Liu, Feng Shi*, Catalytic Asymmetric [3+2] Cycloadditions of C-3 Unsubstituted 2-Indolylmethanols: Regio-, Diastereo- and Enantioselective Construction of the Cyclopenta[b]indole Framework, Adv. Synth. Catal. 2016358(23), 3797-3808.

 

32. Hong-Hao Zhang, Zi-Qi Zhu, Tao Fan, Jing Liang, Feng Shi*, Intermediate-Dependent Unusual [4+3], [3+2] and Cascade Reactions of 3-Indolylmethanols: Controllable Chemodivergent and Stereoselective Synthesis of Diverse Indole Derivatives, Adv. Synth. Catal. 2016358(8), 1259-1288.

 

31. Xiao-Xue Sun, Hong-Hao Zhang, Guo-Hao Li, Ying-Ying He, Feng Shi*, Catalytic Enantioselective and Regioselective [3+3] Cycloadditions Using 2-Indolylmethanols as 3 C Building Blocks, Chem. Eur. J. 201622(49), 17526-17532.

 


30. Wei Dai, Xiao-Li Jiang, Ji-Yu Tao, Feng Shi*, Application of 3-Methyl-2-vinylindoles in Catalytic Asymmetric Povarov Reaction: Diastereo- and Enantioselective Synthesis of Indole-Derived Tetrahydroquinolines, J. Org. Chem 201681(1), 185-192.

 

29. Xue Yang, Yu-Chen Zhang, Qiu-Ning Zhu, Man-Su Tu*, Feng Shi*, Diastereo- and Enantioselective Construction of the Hexahydrocoumarin Scaffold via an Organocatalytic Asymmetric [3 + 3] Cyclization, J. Org. Chem. 201681(12), 5056-5065.

 

28. Qiu-Ning Zhu, Yu-Chen Zhang, Meng-Meng Xu, Xiao-Xue Sun, Xue Yang, Feng Shi*, Enantioselective Construction of Tetrahydroquinolin-5-one-Based Spirooxindole Scaffold via an Organocatalytic Asymmetric Multicomponent [3 + 3] Cyclization, J. Org. Chem. 201681(17), 7898-7907.

 

2015

27. Jia-Jia Zhao, Si-Bing Sun, Sai-Huan He, Qiong Wu, Feng Shi*, Catalytic Asymmetric Inverse-Electron-Demand Oxa-Diels-Alder Reaction of In Situ Generated ortho-Quinone Methides with 3-Methyl-2-Vinylindoles, Angew. Chem., Int. Ed. 201554(18), 5460-5464.

 

26. Yang Wang, Meng Sun, Lei Yin and Feng Shi*, Catalytic Enantioselective Arylative Dearomatization of 3-Methyl-2-vinylindoles Enabled by Reactivity Switch, Adv. Synth. Catal. 2015357(18), 4031-4040.

 


25. Fei Jiang, Yu-Chen Zhang, Si-Bing Sun, Lu-Jia Zhou, Feng Shi*, Organocatalytic Reactions of Indoles with Quinone Imine Ketals: An Alternative Metal-Free Approach to Bioactive meta-Indolylanilines, Adv. Synth. Catal. 2015357(6), 1283-1292.

 

24. Feng Shi*, Hong-Hao Zhang, Xiao-Xue Sun, Jing Liang, Tao Fan, Shu-Jiang Tu, Organocatalytic Asymmetric Cascade Reactions of 7-Vinylindoles: Diastereo- and Enantioselective Synthesis of C7-Functionalized Indoles, Chem. Eur. J. 201521(8), 3465-3471.

 

23. Cong-Shuai Wang, Ren-Yi Zhu, Jian Zheng, Feng Shi*, Shu-Jiang Tu, Enantioselective Construction of Spiro[indoline-3,2'-pyrrole] Framework via Catalytic Asymmetric 1,3-Dipolar Cycloadditions Using Allenes as Equivalents of Alkynes, J. Org. Chem. 201580(1), 512-520.

 

22. Xin Li, Wei Tan, Yu-Xin Gong, Feng Shi*, Catalyst-Controlled Chemoselective Reaction of 3-Indolylmethanols with Cyclic Enaminones Leading to C2-Functionalized Indoles, J. Org. Chem. 201580(3), 1841-1848.

 


21. Yang Wang, Man-Su Tu, Lei Yin, Meng Sun, Feng Shi*, Bronsted Acid Catalyzed Asymmetric Diels-Alder Reactions: Stereoselective Construction of Spiro[tetrahydrocarbazole-3,3'-oxindole] Framework, J. Org. Chem. 201580 (6), 3223-3232.

 

20Wei Dai, Xiao-Li Jiang, Qiong Wu, Feng Shi*, Shu-Jiang Tu, Diastereo- and Enantioselective Construction of 3,3’-Pyrrolidinyldispirooxindole Framework via Catalytic Asymmetric 1,3-Dipolar Cycloadditions, J. Org. Chem. 201580(11), 5737-5744.

 

 

19. Jia-Jia ZhaoYu-Chen ZhangMeng-Meng XuMan Tang, and Feng Shi*, Catalytic Chemo-, E/Z-, and Enantioselective Cyclizations of o-Hydroxybenzyl Alcohols with Dimedone-Derived Enaminones, J. Org. Chem. 2015, 80(20), 10016−10024.

 

18. Cong-Shuai Wang, Ren-Yi Zhu, Yu-Chen Zhang and Feng Shi*, Catalytic Chemoselective [3+3] Cycloadditions of Azomethine Ylides with Quinone Monoimides Leading to the Construction of A Dihydrobenzoxazine Scaffold, Chem. Commun. 201551(59), 11798-11801.

 

 

17. Xiao-Xue Sun, Bai-Xiang Du, Hong-Hao Zhang, Lei Ji, Feng Shi*, Catalytic Asymmetric Arylation of 3-Indolylmethanols: Enantioselective Synthesis of 3,3'-Bis(indolyl)oxindoles with High Atom Economy, ChemCatChem. 20157(7), 1211-1221.

 

 

2014

16. Yu-Chen Zhang, Jia-Jia Zhao, Fei Jiang, Si-Bing Sun, Feng Shi*, Organocatalytic Asymmetric Arylative Dearomatization of 2,3-Disubstituted Indoles Enabled by Tandem Reactions, Angew. Chem., Int. Ed. 201453(50), 13912-13915.

 

15. Yu-Chen Zhang, Fei Jiang, Shu-Liang Wang*, Feng Shi*Shu-Jiang Tu , Organocatalytic Chemo- and Regioselective Oxyarylation of Styrenes via a Cascade Reaction: Remote Activation of Hydroxyl Groups, J. Org. Chem. 2014, 79(13), 6143-6152.

 

14. Hong-Hao Zhang, Yue-Ming Wang, Yuan-Wei Xie, Zi-Qi Zhu, Feng Shi*, Shu-Jiang Tu, Organocatalytic Chemo-, (E/Z)- and Enantioselective Formal Alkenylation of Indole-Derived Hydroxylactams Using o-Hydroxystyrenes as a Source of Alkenyl Group, J. Org. Chem. 201479(15), 7141-7151.

 

13. Ren-Yi Zhu, Cong-Shuai Wang, Jian Zheng, Feng Shi*, Shu-Jiang Tu,  Organocatalytic Asymmetric Inverse-Electron-Demand 1,3-Dipolar Cycloaddition of N,N'-Cyclic Azomethine Imines, J. Org. Chem. 201479(19), 9305-9312.

 


12. Lu-Jia Zhou, Yu-Chen Zhang, Jia-Jia Zhao, Feng Shi*, Shu-Jiang Tu,  Organocatalytic Arylation of 3-Indolylmethanols via Chemo- and Regiospecific C6-Functionalization of Indoles, J. Org. Chem. 201479(21), 10390-10398.

 

11. Yang Wang, Man-Su Tu, Feng Shi*, Shu-Jiang Tu,  Enantioselective construction of the biologically significant dibenzo[1,4]diazepine scaffold via organocatalytic asymmetric three-component reactions, Adv. Synth. Catal. 2014356(9), 2009-2019.

 

10. Wei Dai, Han Lu, Xin Li, Feng Shi*, Shu-Jiang Tu, Diastereo- and enantioselective construction of a bispirooxindole scaffold containing a tetrahydro-β-carboline moiety through an organocatalytic asymmetric cascade reaction, Chem. Eur. J. 201420(36), 11382-11389.

 

 

9. Feng Shi*, Ren-Yi Zhu, Wei Dai, Cong-Shuai Wang, Shu-Jiang Tu*, Catalytic Asymmetric Formal [3+3] Cycloaddition of an Azomethine Ylide with 3-Indolylmethanol: Enantioselective Construction of a Six-Membered Piperidine Framework, Chem. Eur. J. 201420(9), 2597-2604.

 

8. Yang Wang, Feng Shi*, Xi-Xi Yao, Meng Sun, Liang Dong, Shu-Jiang Tu, Catalytic Asymmetric Construction of 3,3'-Spirooxindoles Fused with Seven-Membered Rings by Enantioselective Tandem Reactions, Chem. Eur. J. 2014, 20(46), 15047-15052.

 


7.Yan Liu, Hong-Hao Zhang, Yu-Chen Zhang, Yan Jiang, Feng Shi*, Shu-Jiang Tu, Organocatalytic enantioselective and (Z)-selective allylation of 3-indolylmethanol via hydrogen-bond activation, Chem. Commun. 201450(81), 12054-12057.

 

6. Wei Tan, Xin Li, Yu-Xin Gong, Meng-Di Ge, Feng Shi*, Highly diastereo- and enantioselective construction of a spiro[cyclopenta[b]indole-1,3'-oxindole] scaffold via catalytic asymmetric formal [3+2] cycloadditions, Chem. Commun. 201450(100), 15901-15904.

 

5. Wei Tan, Bai-Xiang Du, Xin Li, Xu Zhu, Feng Shi*, Shu-Jiang Tu, Catalytic Asymmetric Aza-ene Reaction of 3-Indolylmethanols with Cyclic Enaminones: Enantioselective Approach to C3-Functionalized Indoles, J. Org. Chem. 201479(10), 4635-4643.

 

2013

4. Feng Shi*, Gui-Juan Xing, Ren-Yi Zhu, Wei Tan, Shu-jiang Tu*, A Catalytic Asymmetric Isatin-Involved Povarov Reaction: Diastereo- and Enantioselective Construction of Spiro[indolin-3,2'-quinoline] Scaffold, Org. Lett. 201315(1), 128-131.

 


3. Feng Shi*, Ren-Yi Zhu, Xia Liang, Shu-Jiang Tu*,  Catalytic Asymmetric 1,3-Dipolar Cycloadditions of Alkynes with Isatin-Derived Azomethine Ylides: Enantioselective Synthesis of Spiro[indoline-3,2'-pyrrole] Derivatives, Adv. Synth. Catal. 2013355(11-12), 2447-2458.


2. Feng Shi*, Wei Tan, Hong-Hao Zhang, Mei Li, Qin Ye, Guan-Hua Ma, Shu-Jiang Tu*, Guigen Li, Asymmetric Organocatalytic Tandem Cyclization/Transfer Hydrogenation: A Synthetic Strategy for Enantioenriched Nitrogen Heterocycles, Adv. Synth. Catal. 2013355(18), 3715-3726.

 

1. Feng Shi*, Wei Tan, Ren-Yi Zhu, Gui-Juan Xing, Shu-Jiang Tu*, Catalytic Asymmetric Five-Component Tandem Reaction: Diastereoselective and Enantioselective Synthesis of Densely Functionalized Tetrahydropyridines with Biological Importance, Adv. Synth. Catal. 2013355(8), 1605-1622.