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成果及论文

Selected Publication:

* Corresponding author;   # Co-first author

  1. Chen, Z.#; Chen, W.#; Xu, C.#; Song, H.; Ji, X.; Jiang, H.; Duan, H.; Li, Z.; Gao, W.; Yao, T.; Zhang, Z.; He, L.; Yin, Y.; Yang, N.; Tian, W.; Wu, J.; Li, X.* Near-infrared fluorogenic RNA for in vivo imaging and sensing. Nature Communications (IF=16.6), 2024, Accepted.

  2. Zhang, Z.#; Rong, X.#; Xie, T.; Song, H.; Li, Z.; Zhen, S.; Wu, J.; Jaffrey, S R. and Li, X.* Fluorogenic CRISPR for genomic DNA imaging. Nature Communications (IF=16.6), 2024, 15, 934.

  3. Zhang, Y.#; Xu, Z.#; Xiao, Y.#; Jiang, H.#; Zuo, X.; Li, X.* and Fang, X.* Structural mechanisms for binding and activation of a contact-quenched fluorophore by RhoBAST. Nature Communications (IF=16.6), 2024, 15, 4026.  

  4. Chen, Z.; Chen, W.; Zhayila, R.; Jiang, H.; Wu, J.; and Li, X.* Genetically encoded RNA-based sensors with Pepper fluorogenic aptamer. Nucleic Acids Research (IF=14.9), 2023, 51 (16), 8322–8336. 

  5. Chen, W.#; Zhao, X.#; Yang, N.*; Li, X.*  Single mRNA imaging with fluorogenic RNA aptamers and small-molecule fluorophores. Angewandte Chemie International Edition (IF=16.6), 202362 (7), e202209813. 


Publications at CAS


2024年

4. Near-infrared fluorogenic RNA for in vivo imaging and sensing

Chen, Z.#; Chen, W.#; Xu, C.#; Song, H.; Ji, X.; Jiang, H.; Duan, H.; Li, Z.; Gao, W.; Yao, T.; Zhang, Z.; He, L.; Yin, Y.; Yang, N.; Tian, W.; Wu, J.; Li, X.* 

Nature Communications (IF=16.6), 2024, Accepted


3. Structural mechanisms for binding and activation of a contact-quenched fluorophore by RhoBAST

Zhang, Y.#; Xu, Z.#; Xiao, Y.#; Jiang, H.#; Zuo, X.; Li, X.* and Fang, X.*  

Nature Communications (IF=16.6), 2024, 15, 4026.

Link


2. Fluorogenic CRISPR for genomic DNA imaging

Zhang, Z.#; Rong, X.#; Xie, T.; Song, H.; Li, Z.; Zhen, S.; Wu, J.; Jaffrey, S R; and Li, X.*

Nature Communications (IF=16.6), 202415, 934.

Link

BioArt News


1. Progress in RNA dynamic imaging technology in live cells 

Gao, W.; Chen, Z.; Rong,  X.; and Li, X.* 

Scientia Sinica Vitae (Invited Review), 2024, 54, 651–667.

Link



2023年

5. Genetically encoded RNA-based sensors with Pepper fluorogenic aptamer

Chen, Z.; Chen, W.; Zhayila, R.; Jiang, H.; Wu, J.; and Li, X.*

Nucleic Acids Research (IF=14.9), 2023, 51 (16), 8322–8336.

Link

CAS News

BioArt News


4. Intricate 3D architecture of a DNA mimic of green fluorescent protein

Passalacqua, L. F. M.; Banco, M. T.; Moon, J. D.; Li, X.; Jaffrey, S. R.; and Ferré-D’Amaré, A. R.* 

Nature (IF=64.8), 2023, 618, 1078-1084.

Link

BioArt News



3. In situ self-assembly of fluorogenic RNA nanozipper enables real-time imaging of single viral mRNA translation

Zhang, Y.#; Wang, Z.#; Tian, Y.; Jiang, H.; Zhao, L.; Kong, D.; Li, X.; Pang, D.; Liu, S.*

Angewandte Chemie International Edition (IF=16.6), 2023, e202217230.

Link



2. In vivo single-molecule RNA structural profiling

Chen, Z.#; Duan, H.#; and Li, X.*

Trends in Biochemical Sciences (IF=13.8), 2023, 48 (3), 211-212.

Link

Biols News


1.  Single mRNA imaging with fluorogenic RNA aptamers and small-molecule fluorophores

Chen, W.#; Zhao, X.#; Yang, N.*; and Li, X.*

Angewandte Chemie International Edition (IF=16.6), 2023, e202209813.

Link


2022年

2. The fluorescent aptamer Squash extensively repurposes the adenine riboswitch fold

Truong, L.; Kooshapur, H.; Dey, S. K.; Li, X.; Tjandra, N.; Jaffrey, S. R.; and Ferré-D’Amaré, A. R.* 

Nature Chemical Biology (IF=14.8), 2022, 18 (2), 191-198.

Link


1. Self-assembly of intracellular multivalent RNA complexes using dimeric Corn and Beetroot aptamers. 

Wu, J.; Svensen, N.; Song, W.; Kim, H.; Zhang, S.; Li, X.; and Jaffrey, S. R.*

Journal of the American Chemical Society (IF=15.0), 2022, 144 (12), 5471-5477.

Link

Abstract Image


2021年

2.  Engineering fluorophore recycling in a fluorogenic RNA aptamer. 

Li, X.*; Wu, J.; and Jaffrey, S. R.*

Angewandte Chemie International Edition (IF=16.6), 2021, 60 (45), 24153-24161.

Link

CAS News


1. Label-free bioassay with graphene oxide-based fluorescent aptasensors: A review. 

Ma, K.; Li, X.*; Xu, B.;  and Tian, W. 

Analytica Chimica Acta (IF=6.911. Invited Review), 2021, 1188, 338859. 

Link