Independent Work

32. Yang Liu, Ye-Wei Chen, Yuan-Xiang Yang, John F. Hartwig*, Zhi-Tao He*. Asymmetric Amination of Unstrained C(sp³)–C(sp³) Bonds. J. Am. Chem. Soc. 2024, 146, 29857–29864.

Higlighted by 化学深耕堂，X-MOL，SIOC

31. Jing-Ming Zhang, Zhi-Tao He*. Transition metal-catalyzed asymmetric migratory allylic C-H functionalization of remote dienes. Chin. J. Org. Chem., 2024, doi: 10.6023/cjoc202406047. (Invited Review for a special topic)

30. Ming-Qiao Tang, Zi-Jiang Yang, Ai-Jun Han, and Zhi-Tao He*. Diastereoselective and Enantioselective Hydrophosphinylations of Conjugated Enynes, Allenes and Dienes via Synergistic Pd/Co Catalysis. Angew. Chem. Int. Ed. 2024, 63, e202413428. 

Highlighted by 化学深耕堂, SIOC, X-MOL

29. Zi-Han Li, Jiang-Shan Ma, Han-Yu Lu, Guo-Qiang Lin, Zhi-Tao He*. Asymmetric Multicomponent Propargylations via Carbon Dioxide Shuttling and Fixation. ACS Catal. 2024, 14, 11646−11656.

Highlighted by CBG

28. Bo-Yuan Xie, Zhi-Tao He*. Chemodivergent Tandem Hydroalkylation and Hydroalkenoxylation of Conjugated Enynes. ACS Catal. 2024, 14, 9742–9751. 

Highlighted by CBG

27. Ye-Wei Chen^#, Yehao Qiu^#, Yang Liu, Guo-Qiang Lin, John F. Hartwig*, Zhi-Tao He*. Intermolecular asymmetric functionalization of unstrained C(sp3)–C(sp3) bonds in allylic substitution reactions. Nat. Synth. 2024, 3, 1011–1020.

Highlighted by 科服，化学深耕堂，SIOC，Nat Synth，顶刊动态，Synfacts

26. Chao Ma,^# Liang Chen,^#  Zhi-Tao He*. Asymmetric Intramolecular O-Hydroximation of Alkynes. CCS Chem. 2024, DOI: 10.31635/ccschem.024.202404296.

Highlighted by 杭高院，化学深耕堂

25. Jing-Ming Zhang, Yu-Chao Wang, Liang Chen, Chao Ma, Zhi-Tao He*. Stereoselective Synthesis of Polysubstituted Dihydropyrroles via 1,5-Addition and N-1,4-Addition Cascade. Chem. Eur. J. 2024, e202401350.

24.  Yu-Ze Sun, Guo-Qiang Lin, Zhi-Tao He*. Copper-Catalyzed [4+1] and [4+2] Reactions via Tandem Remote Propargylation/Cyclization/Isomerization with Amine and Hydrazine. Synlett, 2024, 10.1055/a-2294-5395.

23. Han-Yu Lu, Zi-Han Li, Guo-Qiang Lin, Zhi-Tao He*. Asymmetric Copper-Catalyzed Alkynylallylic Monofluoroalkylations with Fluorinated Malonates. Chem. Commun. 2024, 60, 4210-4213.

22. Ai-Jun Han, Qitao Tan,^* Zhi-Tao He^*. Palladium-Catalyzed Asymmetric O-1,5-Addition with Oximes via Hydroximation of Unsaturated Esters. Org. Lett. 2024, 26, 89–93.

21. Zi-Jiang Yang, Zhi-Tao He*. Stereodivergent 1,5-Conjugate Addition with Iminoesters via Pd/Cu Dual Catalysis. Synthesis 2024. 56, 3412-3420. (Invited for a special topic)

20. Si-Yuan Luo, Guo-Qiang Lin, Zhi-Tao He*. Asymmetric Copper-Catalyzed Alkynylallylic Dimethylamination. Org. Chem. Front., 2024, 11, 690-695. (Invited for Organic Chemistry Frontiers Emerging Investigator)

19. Yu-Ze Sun,^# Zi-Yang Ren,^# Yuan-Xiang Yang, Yang Liu, Guo-Qiang Lin*, Zhi-Tao He*. Asymmetric Substitution by Alkynyl Copper Driven Dearomatization and Rearomatization. Angew. Chem. Int. Ed. 2023, 62, e202314517.

Highlighted by X-MOL, SIOC

18. Ming-Qiao Tang^#, Zi-Jiang Yang^#, Zhi-Tao He*. Asymmetric Formal sp2-Hydrocarbonations of Dienes and Alkynes via Palladium Hydride Catalysis. Nat. Commun. 2023, 14, 6303.

Highlighted by CBG, SIOC, Synfacts, Organic Chemistry Portal

17.  Xian-Xiao Chen, Zhi-Tao He.* Transition Metal-Catalyzed Migratory Tsuji-Trost Reaction. ChemCatChem, 2023, e202301073. (Invited Concept)

16. Xian-Xiao Chen, Zhi-Tao He.* Palladium-catalyzed asymmetric allylation via directed migration of remote dienes. Chin. Sci. Bull. 2023, 68, 3410 - 3412. (Invited Highlight)

15. Xian-Xiao Chen,^# Hao Luo,^# Ye-Wei Chen, Yang Liu, Zhi-Tao He.* Enantioselective Palladium-Catalyzed Directed Migratory Allylation of Remote Dienes. Angew. Chem. Int. Ed. 2023, 62, e202307628.

Highlighted by SIOC, X-MOL

14. Yang Liu, Zhi-Tao He.* Synergistic Organo/Metal-Catalyzed Asymmetric Allenylic Substitution with Aldehyde for the Construction of 1,3-Nonadjacent Stereocenter and Chiral Axis. Chin. J. Org. Chem. 2023, 43, 1896-1897. (Invited Highlight)

13. Yu-Chao Wang, Jin-Biao Liu*, Zhi-Tao He*. Palladium-Catalyzed Asymmetric Hydrofunctionalizations of Conjugated Dienes. Chin. J. Org. Chem. 2023, 43, 2614-2627. (invited Review)

12. Qi-Ying Liao^#, Chao Ma^#, Yu-Chao Wang, Shao-Qian Yang, Jiang-Shan Ma, Zhi-Tao He*. Enantioselective and stereodivergent hydromonofluoroalkylation of conjugated and remote dienes. Chin. Chem. Lett. 2023, 34, 108371.

11. Xin Wang, Han-Zhe Miao, Guo-Qiang Lin*, Zhi-Tao He*. Ligand-Dictated Regiodivergent Allylic Functionalizations via Palladium-Catalyzed Remote Substitution. Angew. Chem. Int. Ed. 2023, 62, e202301556.

Highlighted by SIOC, CBG, Advances in Enginering

10. Shao-Qian Yang, Ai-Jun Han, Yang Liu, Xin-Yuan Tang, Guo-Qiang Lin*, Zhi-Tao He*. Catalytic Asymmetric Hydroalkoxylation and Formal Hydration and Hydroaminoxylation of Conjugated Dienes. J. Am. Chem. Soc. 2023, 145, 3915-3925.

Highlighted by SIOC, X-MOL, CJOC

9. Han-Yu Lu, Zhi-Tao He*. Catalytic Asymmetric Synthesis of 1,4-Enynes. Chin. Chem. Lett. 2023, 34, 108105. (Review)

8. Yu-Chao Wang,# Zhao-Xin Xiao,# Miao Wang,# Shao-Qian Yang, Jin-Biao Liu, Zhi-Tao He*. Umpolung Asymmetric 1,5-Conjugate Addition via Palladium Hydride Catalysis. Angew. Chem. Int. Ed. 2023, 62, e202215568.

Highlighted by SIOC, CBG

7. Chao Ma^#, Ye-Wei Chen^#, Zhi-Tao He^*. Recent progress in Pd-catalyzed asymmetric hydrofunctionalizations of dienes and enynes. Sci. Sin. Chim. 2023, 53, 474-484. (invited Review)

6. Jiang-Shan Ma^#, Han-Yu Lu^#, Ye-Wei Chen, Wei-Cheng Zhao, Yu-Ze Sun, Rui-Peng Li, Hu-Xiao Wang, Guo-Qiang Lin*, Zhi-Tao He*. Copper-Catalyzed Convergent Regio- and Enantioselective Alkynylallylic Substitution. Nat. Synth. 2023, 2, 37-48.

Highlighted by Nat. Syn., X-MOL, SIOC, 科学网，化学加

5. Han-Zhe Miao, Yang Liu, Ye-Wei Chen, Han-Yu Lu, Jian Li*, Guo-Qiang Lin*, Zhi-Tao He*. Stereoselective Pd-Catalyzed Remote Hydroamination of Skipped Dienes with Azoles. Synlett, 2023, 34, 451-456. (Invited for 2022 Thieme Chemistry Journals Award)

4.  Zhi-Tao He*. P(III)-Promoted 1,2-Boronate Migration and Application to the Stereoselective gem-C,B-Glycosylation. Synlett, 2022, 33, 1103-1107. (Invited Synpacts)

3. Wei-Cheng Zhao,^# Rui-Peng Li,^# Chao Ma, Qi-Ying Liao, Miao Wang, Zhi-Tao He*. Stereoselective gem-C,B-Glycosylation via 1,2-Boronate Migration. J. Am. Chem. Soc. 2022, 144, 2460-2467.

Highlighted by CBG，X-mol, SIOC

2.  Ye-Wei Chen,# Yang Liu,# Han-Yu Lu, Guo-Qiang Lin*, Zhi-Tao He*. Palladium-Catalyzed Regio- and Enantioselective Migratory Allylic C(sp³)-H Functionalization. Nat. Commun. 2021, 12, 5626.

Highlighted by SIOC，CBG，X-MOL, Organic Chemistry Portal

volume,12, Article number: 5626 (2021)

1. Shao-Qian Yang,^# Yi-Fan Wang,^# Wei-Cheng Zhao, Guo-Qiang Lin*, Zhi-Tao He*. Stereodivergent Synthesis of Tertiary Fluoride-Tethered Allenes via Copper and Palladium Dual Catalysis. J. Am. Chem. Soc. 2021, 143, 7285–7291.

Highligted by SIOC, CBG，CAS，CJOC

Cooperative work

8. Yehao Qiu, Vienna C.J.X. Thomas , Tommaso Fantoni, Reichi Chen, Xingyu Jiang, Zhi-Tao He, Trevor W. Butcher, Daniel K. Nomura^*, John F. Hartwig*. Convergent synthesis and protein binding of vicinal difluorides by stereodivergent C–C bond formation. Chem, 2024, DOI: 10.1016/j.chempr.2024.08.024.

7. Ze-Jian Xue, Meng-Yao Li, Bin-Bin Zhu, Zhi-Tao He,* Chen-Guo Feng* and Guo-Qiang Lin*. A 1,4-Palladium Migration/Heck Sequence with Unactivated Alkenes: Stereoselective Synthesis of Trisubstituted 1,3-Dienes. Adv. Synth. Catal. 2021, 363, 2089– 2092.

6. Bin-Bin Zhu, Wen-Bo Ye, Zhi-Tao He, Shu-Sheng Zhang, Chen-Guo Feng,* and Guo-Qiang Lin*. Regioselective Tandem C−H Alkylation/Coupling Reaction of ortho-Iodophenylethylenes via C,C‑Pallada(II)cycles. ACS Catal. 2021, 11, 12123−12132.

5. Ge Zhang, Meng-Yao Li, Wen-Bo Ye, Zhi-Tao He, Chen-Guo Feng*, Guo-Qiang Lin*. Borylation of Unactivated C(sp3)–H Bonds with Bromide as a Traceless Directing Group. Org. Lett. 2021, 23, 8, 2948–2953.

4. Kai-Rui Feng,# Yun-Xuan Tan,# Wenbo Ye, Yi-Fan Wang, Zhi-Tao He,* Ping Tian,* and Guo-Qiang Lin*. One-Pot Preparation of Tricyclo[5.2.2.04,9]undecanes via Cu-Catalyzed Asymmetric Carboboration of Cyclohexadienone-Tethered Allenes. Org. Lett. 2021, 23, 607−611.

3. Wei-Cheng Zhao#, Xin Wang#, Juhua Feng,* Ping Tian,* Zhi-Tao He*. Palladium-catalyzed desymmetric [2+2+2] cycloaddition of 1,6-enyne and alkyne. Tetrahedron, 2021, 79, 131862. (Invited paper, in honor of Prof. Guo-Qiang Lin)

2. Ze-Jian Xue, Meng-Yao Li, Bin-Bin Zhu, Zhi-Tao He,* Chen-Guo Feng* and Guo-Qiang Lin*. Stereoselective Synthesis of Conjugated Trienes via 1,4-Palladium Migration/Heck Sequence. Chem. Commun., 2020, 56, 14420-14422.

1. Yun-Xuan Tan#, Xing-Yu Liu#, Shuo-Qing Zhang#, Pei-Pei Xie, Xin Wang, Kai-Rui Feng, Shao-Qian Yang, Zhi-Tao He*, Xin Hong*, Ping Tian* and Guo-Qiang Lin*, An Unconventional trans-exo-Selective Cyclization of Alkyne-Tethered Cyclohexadienones Initiated by Rhodium(III)-Catalyzed C--H Activation via Insertion Relay. CCS Chemistry, 2020, 2, 1582–1595.

Bofore Independence

13. He, Z.-T.; Hartwig, J. F.* Enantioselective α-Functionalizations of Ketones via Allylic Substitution of Silyl Enol Ether. Nat. Chem. 2019, 11, 177. (Highlighted by Synfacts, 2019, 15, 0149; X-MOL)

12. He, Z.-T.; Hartwig, J. F.* Palladium-Catalyzed α-Arylation for the Addition of Small Rings to Aromatic Compounds. Nat. Commun. 2019, 10, 4083.

11. He, Z.-T.; Hartwig, J. F.* Palladium-Catalyzed α-Arylation of Carboxylic Acids and Secondary Amides via a Traceless Protecting Strategy. J. Am. Chem. Soc. 2019, 141, 11749. (Highlighted by Org. Process Res. Dev. 2019, 1773.; Synfacts, 2019, 15, 1137.)

10. He, Z.-T.;# Jiang, X.-Y.#; Hartwig, J. F.* Stereodivergent Construction of Tertiary Fluorides in Vicinal Stereogenic Pairs by Allylic Substitutions with Iridium and Copper Catalysts. J. Am. Chem. Soc. 2019, 141, 13066.

9. He, Z.-T.; # Li, H.; # Haydl, A. M.; Whiteker, G. T.; Hartwig, J. F.* Trimethylphosphate as a Methylating Agent for Cross Coupling: A Slow-release Mechanism for the Methylation of Arylboronic Esters. J. Am. Chem. Soc. 2018, 140, 17197.

8. Zhao, Y.-S.; Liu, J.-K.; He, Z.-T.; Tao, J.-C.*; Tian, P.*; Lin, G.-Q. Two Phenyls are Better than One or Three: Synthesis and Application of Terminal Olefin-Oxazoline (TOlefOx) Ligands. Org. Biomol. Chem., 2016, 14, 3686.

7. He, Z.-T.; Tang, X.-Q.; Xie, L.-B.; Cheng, M.; Tian, P.*; Lin, G.-Q. Efficient Access to Bicyclo[4.3.0]nonanes: Cu-Catalyzed Asymmetric Silylative Cyclization of Cyclohexadienone-tethered Allenes. Angew. Chem., Int. Ed. 2015, 54, 14815.

6. Fukui, Y.; Liu, P.; Liu, Q.; He, Z.-T.; Wu, N.-Y.; Tian, P.*; Lin, G.-Q.* Tunable Arylative Cyclization of 1,6-Enynes Triggered by Rhodium(III)-Catalyzed C−H Activation. J. Am. Chem. Soc. 2014, 136, 15607.

5. He, Z.-T.; Zhao, Y.-S.; Tian, P.*; Wang, C.-C.; Dong, H.-Q.; Lin, G.-Q.* Cu-Catalyzed Asymmetric Hydroboration of a-Dehydroamino Acid Derivates: Facile Synthesis of Chiral b-Hydorxy-a-Amino Acids. Org. Lett. 2014, 16, 1426. (Highlighted by Synfacts, 2014, 10, 499.)

4. Liu, P.; Fukui, Y.; Tian, P.*; He, Z.-T.; Sun, C.-Y.; Wu, N.-Y.; Lin, G.-Q.* Cu-Catalyzed Asymmetric Borylative Cyclization of Cyclohexadienone-Containing 1,6-Enynes. J. Am. Chem. Soc. 2013, 135, 11700.

3.  He, Z.-T.; Tian, B.; Fukui, Y.; Tong, X.; Tian, P.*; Lin, G.-Q.* Rhodium-Catalyzed Asymmetric Arylative Cyclization of meso-1,6-Dienynes Leading to Enantioenriched cis-Hydrobenzofurans. Angew. Chem., Int. Ed. 2013, 52, 5314. (Highlighted by Chin. J. Org. Chem. 2013, 33, 1591.)

2.  Shen, A.; He, Z.-T.; Yu, H.-J.; Fukui, Y.; Tian, P.*; Lin, G.-Q.* Zinc-Mediated Asymmetric Allylation of Chiral N-tert-Butanesulfinyl Aldimines with 3-Bromomethyl-5H-furan-2-one. Synlett 2013, 24, 1649.

1.  He, Z.-T.; Wei, Y.-B.; Yu, H.-J.; Sun, C.-Y.; Feng. C.-G.; Tian, P.*; Lin, G.-Q.* Rhodium/Diene-Catalyzed Asymmetric Arylation of N-Boc-protected α,β-Unsaturated δ-Lactam with Arylboronic Acids: Enantioselective Synthesis of 4-Aryl-2-Piperidinones. Tetrahedron 2012, 68, 9186.

PATENTS

2. 何智涛，张瑄，陈先枭；一种三价膦苷类化合物及其制备方法和应用，2024-08，专利申请号：202411093963.0

1. 何智涛，林国强，杨少倩；一类双齿膦-亚胺配体及制备方法和应用，2022-05, 专利申请号：CN202210567734.2

Invited Reports

15. 第十一届全国分子手性学术研讨会，浙江杭州，2024-10-27，邀请报告

14. 中国化学会第34届学术年会，广东广州，2024-06-16，口头报告

13. 华中科技大学同济药学第15期青年沙龙，湖北武汉，2024-04-25，邀请报告

12. 第18届全国有机合成化学学术研讨会，安徽芜湖，2024-04-18，青年邀请报告

11. 第四届催化与合成浦江论坛，上海有机所，2024-04-14，邀请报告

10. 常州大学石油化工学院学术交流，江苏常州大学，2024-03-07，邀请报告

9. 武汉大学高等研究院学术交流，武汉大学，2024-01-16，邀请报告

8. “中国化学”(Chin. J. Chem. ) 期刊第20期云论坛，2023-12-22，线上邀请报告

7. 华东师范大学学术报告交流，上海华东师范大学，2023-11-22，邀请报告

6. 南京师范大学【名师讲坛】邀请专家报告，南京师范大学，2023-06-28，邀请报告

5. 中国化学会第33届学术年会，山东青岛，2023-06-19，口头报告

4. 上海科技大学物质科学与技术学院学术交流，上海科技大学，2023-03-17，邀请报告

3. “研途-分享荟”SIOC青年沙龙-上海有机所青促会学术交流，上海有机所，2022-10-12, 邀请报告

2. 中国化学会第12届全国有机化学学术会议，安徽合肥，2022-09-27，口头报告

1. 上海分子治疗与新药创制工程技术研究中心“合成创造未来 ”讲座，华东师范大学，2022-07-30, 线上邀请报告