Official journal of CSOS and ICMRS

The Journal of Orthopaedic Translation (JOT) is the official peer-reviewed, open access journal of the Chinese Speaking Orthopaedic Society (CSOS) and the International Chinese Musculoskeletal Research Society (ICMRS). It is published bimonthly, in January, March, May, July, September and November, by Elsevier.

The Journal focuses on the rapidly growing field of orthopaedic translational research. While there are a number of high quality orthopaedic journals, none are solely dedicated to the field of orthopaedic translational research. The importance of translational research is quickly being recognized by all spectrums of the scientific community, from clinicians to basic science researchers. To truly improve the health of people, scientific research on the cellular and molecular level must be utilized and applied appropriately in the clinical setting. A journal that is purely dedicated to the art of translational research is a monumental step in the advancement of musculoskeletal care by bringing cutting edge knowledge to the forefront and allowing pioneers of orthopaedic translation to exchange and mutually enhance expertise. JOT aims to be that linking factor and welcomes high quality manuscripts that will advance the field of orthopaedic translation.

JOT is devoted to research and issues of strong interest in translational medicine on musculoskeletal and related themes. Material that are considered include any original research findings, discussions or analyses that will move the field closer to the goal of improving musculoskeletal health, diagnosis, prevention, and treatment of musculoskeletal disorders or injuries. Multidisciplinary approaches are particularly encouraged. We accept original research papers, review articles, editorials, perspectives, case reports and letters to the Editor.

The main goal of JOT is to publish papers that identify and fill scientific knowledge gaps at the junction of basic research and clinical application (from bench to bedside) or community application (from bench to community). In this vein, original research should report significant progress toward the prevention, diagnosis, and treatment of musculoskeletal disorders and serve as templates for future exploration and investments in translational orthopaedics.

Original papers are categorized into the following topics:
Animal models
Biomaterials
Biophysical stimulation
Clinical trials
Diagnostics
Health promotion
Industries and markets
Medical devices and implants
Nutrition and drugs
Regenerative medicine
Regulations and policies
Rehabilitation


Indexed in: DOAJ, Embase, ESCI (Emerging Sources Citation Index), ScienceDirect, Scopus, SCIE (Science Citation Index Expanded)

Original articles
Review articles
Editorials
Perspectives
Case reports
Letters to the Editor

Editors-in-Chief
Professor Regis O'Keefe
Washington University in Saint Louis Department of Orthopaedic Surgery, Saint Louis, Missouri, United States Email Professor Regis O'Keefe
Professor Ling Qin
The Chinese University of Hong Kong, Prince of Wales Hospital, Department of Orthopaedics & Traumatology, Shatin, N.T, Hong Kong Email Professor Ling Qin
Editorial Offices
Journal of Orthopaedic Translation (HK)
Department of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Room 74029, 5/F, Lui Che Woo Clinical Sciences Building, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR Phone +852 2632-2798 / 2646-1477 Email Journal of Orthopaedic Translation (HK)
Journal of Orthopaedic Translation (Shanghai)
Shanghai Key Laboratory of Orthopaedic Implants, Department of Orthopaedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Room 701, No. 3 Building, 639 Zhizaoju Road, Shanghai, China Phone +86 21 5331-5397
Executive Associate Editors
Professor Gang Li
Chinese University of Hong Kong Department of Orthopaedics and Traumatology, Hong Kong, Hong Kong
Professor Ting-ting Tang
Shanghai 9th Peoples Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China
Associate Editors
Dr. Di Chen
Rush Medical College of Rush University, Chicago, Illinois, United States
Dr. Harry K. Genant
University of California at San Francisco Department of Orthopaedic Surgery, San Francisco, California, United States
Professor Ling Qin
University of Pennsylvania, Philadelphia, Pennsylvania, United States
Professor Geoff Richards
AO Foundation, Davos Platz, Switzerland
Dr. Hui-lin Yang
First Affiliated Hospital of Soochow University, Suzhou, China
Board of Trustees
Professor Kai-ming Chan
The Chinese University of Hong Kong, Prince of Wales Hospital, Department of Orthopaedics & Traumatology, Shatin, N.T., Hong Kong
Professor Zhong-qiang Chen
Peking University Third Hospital, Beijing, China
Dr. Cheng-Kung Cheng
BeiHang University School of Biological Science and Medical Engineering, Beijing, China
Professor Yan Wang
Chinese PLA General Hospital, Beijing, China
Managing Editors
Bruma Sai-chuen Fu
Chinese University of Hong Kong Department of Orthopaedics and Traumatology, Hong Kong, Hong Kong
Chelsea Hopkins
The Chinese University of Hong Kong, Prince of Wales Hospital, Department of Orthopaedics & Traumatology, Shatin, N.T, Hong Kong
Kritika Tiwari
The Chinese University of Hong Kong, Prince of Wales Hospital, Department of Orthopaedics & Traumatology, Shatin, N.T, Hong Kong
Zhifeng Yu
Shanghai 9th Peoples Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China
Section Editors – Animal Models
Lin Chen
Army Medical University, Chongqing, China
Hong Zhou
ANZAC Research Institute, Concord, Australia
Section Editors – Biomaterials
Chengtie Wu
Shanghai Institute of Ceramics Chinese Academy of Sciences, Changning District, China
Liming Bian
Chinese University of Hong Kong Department of Biomedical Engineering, Hong Kong, Hong Kong
Section Editors – Biophysical Stimulation
Louis Wing-Hoi Cheung
Chinese University of Hong Kong Department of Orthopaedics and Traumatology, Hong Kong, Hong Kong
Section Editors – Clinical Trials
Weibo Xia
Peking Union Medical College Hospital Key Laboratory of Endocrinology, Chinese Academy of Medical Sciences, Beijing, China
Section Editors – Diagnostics
Jiake Xu
The University of Western Australia Division of Pathology and Laboratory Medicine, Crawley, Western Australia, Australia
Section Editors – Health Promotion and Sports Medicine
Hongbin Lu
Xiangya Hospital Central South University Key Laboratory of Organ Injury Aging and Regenerative Medicine of Hunan Province, Changsha, China
Patrick Shu-hang Yung
The Chinese University of Hong Kong, Prince of Wales Hospital, Department of Orthopaedics & Traumatology, Hong Kong
Section Editor – Imaging
Xiao-Guang Cheng
Beijing Jishuitan Hospital and Fourth Medical College of Peking University Department of Radiology, Beijing, China
Yi-xiang Wang
Chinese University of Hong Kong, New Territories, Hong Kong
Section Editors – Industries and Markets
Cheng-Kung Cheng
BeiHang University School of Biological Science and Medical Engineering, Beijing, China
Ming-Hao Zheng
University of Western Australia Faculty of Medicine Dentistry and Health Sciences Sir Charles Gairdner Hospital Translational Orthopaedic Research Centre, Perth, Australia
Section Editors – Medical Devices and Implants
William Wei-jia Lu
University of Hong Kong Li Ka Shing Faculty of Medicine Department of Orthopaedics and Traumatology, Hong Kong, Hong Kong
Section Editors – Regenerative Medicine
Zhiyong Zhang
Guangzhou Medical University Translational Research Centre of Regenerative Medicine and 3D Printing Technologies, Guangzhou, China
Bin Li
Soochow University Institute of Orthopedics, Suzhou, China
Section Editor – Regulations and Policies
Ting-fei Xi
Peking University, Advanced Academy of Interdisciplinary Studies, Peking University, Beijing, China
Section Editors – Rehabilitation
Guoan Li
Massachusetts General Hospital - Harvard Medical School Center for Nervous System Repair, Boston, Massachusetts, United States
International Editorial Board Members
Mauro Alini
AO Research Institute Davos, Davos Platz, Switzerland
Xiao-chun Bai
Southern Medical University Department of Cell Biology, Guangzhou, China
Nicola Baldini
University of Bologna School of Medicine and Surgery, Bologna, Italy
Zhengdong Cai
Shanghai Jiaotong University First People's Hospital Department of Orthopaedics, Shanghai, China
Xu Cao
Johns Hopkins University School of Medicine Center for Musculoskeletal Research, Baltimore, Maryland, United States
Barbara Pui Chan
University of Hong Kong Department of Mechanical Engineering, Hong Kong, Hong Kong
Jiang Chang
Shanghai Institute of Ceramics Chinese Academy of Sciences, Changning District, China
Qian Chen
Brown University Department of Orthopaedics, Providence, Rhode Island, United States
Liao Cui
Guangdong Medical University Department of Pharmacology, Zhanjiang, China
Jian-dong Ding
Fudan University Department of Macromolecular Science, Shanghai, China
Ming Ding
University of Southern Denmark Orthopaedic Surgery Research Unit, Odense, Denmark
Shiwu Dong
Army Medical University, Chongqing, China
Yu-feng Dong
LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER, New Orleans, Louisiana, United States
David Eglin
AO Research Institute Davos, Davos Platz, Switzerland
Yu-Bo Fan
BeiHang University School of Economics and Management, Beijing, China
Jürg Andreas Gasser
Novartis Institutes for BioMedical Research Department of Musculoskeletal Diseases, Basel, Switzerland
Claus-Christian Glüer
University Hospital Schleswig-Holstein Campus Kiel Molecular Imaging North Competence Center, Kiel, Germany
Martijn van Griensven
Technical University of Munich, Munchen, Germany
James Griffith
Chinese University of Hong Kong, Shatin, N.T., Hong Kong
Bernd Grimm
Human Motion Institute, Munich, Germany
Xia Guo
The Hong Kong Polytechnic University, Kowloon, Hong Kong
Hendra Hermawan
Laval University Department of Mining, Metallurgical and Materials Engineering, Quebec City, Quebec, Canada
James H.P. Hui
National University Hospital University Orthopaedics Hand and Reconstructive Microsurgery Cluster, Singapore, Singapore
John Yebin Jiang
University of Michigan Department of Radiology, Ann Arbor, Michigan, United States
Qing Jiang
Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital Department of Orthopedics, Nanjing, China
Xiaohua Jiang
The Chinese University of Hong Kong, School of Biomedical Sciences, Faculty of Medicine, Hong Kong
Zhongmin Jin
University of Leeds, Leeds, United Kingdom
David Hua-zhu Ke
The University of Utah Department of Radiology and Imaging Sciences, Salt Lake City, Utah, United States
Charles James Kirkpatrick
University of Mainz Institute of Pathology, Mainz, Germany
Timothy Kwok
Chinese University of Hong Kong School of Biomedical Sciences Stem Cell and Regeneration Program, Shatin, Hong Kong
Wan-Ju Li
University of Wisconsin Madison, Madison, Wisconsin, United States
Yi-ping Li
University of Alabama at Birmingham, Birmingham, Alabama, United States
Zong-Ming Li
Cleveland Clinic, Cleveland, Ohio, United States
Chang-sheng Liu
East China University of Science and Technology, Shanghai, China
Fanxin Long
The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
Zhuojing Luo
Xijing Hospital, Xian, China
Arthur Fuk-Tat Mak
Stem Cell and Regeneration Program, School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong
Jeremy Jian Mao
Columbia University College of Dental Medicine, New York, New York, United States
Theodore Miclau
Orthopaedic Trauma Institute, San Francisco, California, United States
Hong-wei Ouyang
Zhejiang University Center for Stem Cell and Regenerative Medicine, Hangzhou, Zhejiang, China
Haobo Pan
Chinese Academy of Sciences Institute of Biomedicine and Technology, Shenzhen, China
Wilfred C.G. Peh
National University Singapore Department of Diagnostic Radiology, Singapore, Singapore
Jiang Peng
Chinese PLA General Hospital Department of Orthopaedics, Beijing, China
Yi-Xian Qin
Stony Brook University Department of Biomedical Engineering, Stony Brook, New York, United States
Christer G. Rolf
Karolinska Institutet Orthopaedics Research Group, Stockholm, Sweden
Peng Shang
Research and Development Institute of Northwestern Polytechnical University in Shenzhen, Shenzhen, China
Mark P. Staiger
University of Canterbury, Christchurch, New Zealand
Wei Sun
Drexel University Biofabrication Laboratory, Philadelphia, Pennsylvania, United States
Yu-long Sun
Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences, Shenzhen, China
Chao Wan
Chinese University of Hong Kong School of Biomedical Sciences Stem Cell and Regeneration Program, Shatin, Hong Kong
James H.C. Wang
University of Pittsburgh Department of Orthopaedic Surgery, Pittsburgh, Pennsylvania, United States
Min Wang
University of Hong Kong Department of Mechanical Engineering, Hong Kong, Hong Kong
Yong-jun Wang
Shanghai University of Traditional Chinese Medicine Institute of Spine Diseases, Shanghai, China
Lei Wei
Brown University Department of Orthopaedics, Providence, Rhode Island, United States
Regine Willumeit-Römer
Helmholtz Centre Geesthacht Centre for Materials and Coastal Research Division of Materials Design and Characterisation, Geesthacht, Germany
Reinhard Windhager
Medical University of Vienna, Wien, Austria
Frank Witte
Charité Universitätsmedizin Berlin Julius Wolff Institute for Biomechanics and Musculoskeletal Regeneration - Campus Virchow Klinikum, Berlin, Germany
Kwok-chuen Wong
Prince of Wales Hospital, New Territories, Hong Kong
Guozhi Xiao
Southern University of Science and Technology Department of Biology, Shenzhen, China
Yin Xiao
Queensland University of Technology Institute of Health and Biomedical Innovation, Brisbane, Australia
Zhigang Xu
North Carolina Agricultural and Technical State University College of Engineering, Greensboro, North Carolina, United States
Liu Yang
Xijing Hospital Department of Orthopaedics, Xian, China
Peter Yun-zhi Yang
Stanford University Yang Laboratory, Stanford, California, United States
Wei Yu
Peking Union Medical College Hospital Department of Radiology, Beijing, China
Ming Zhang
The Hong Kong Polytechnic University, Department of Health Technology and Informatics, Hong Kong
Peng Zhang
Chinese Academy of Sciences, Beijing, China
Xiao-ling Zhang
Shanghai Jiao Tong University School of Medicine, Shanghai, China
Zhen-Lin Zhang
Shanghai Jiao Tong University - Fahua Campus, Shanghai, China
Dewei Zhao
Affiliated Zhongshan Hospital of Dalian University, Department of Orthopaedics, Dalian, China
Jie Zhao
Shanghai Jiao Tong University - Fahua Campus, Shanghai, China
Yong-ping Zheng
The Hong Kong Polytechnic University Department of Biomedical Engineering, Kowloon, Hong Kong
Yu-feng Zheng
Peking University Department of Material Science and Engineering, Beijing, China
Yi-ting Zhou
Zhejiang University School of Medicine, Zhejiang University School of Medicine, Hangzhou, China
Qing'an Zhu
Southern Medical University Nanfang Hospital Department of Spinal Surgery, Guangzhou, China
Advisory Board Members
Kai-Nan An
Mayo Clinic Department of Orthopedic Surgery, Rochester, Minnesota, United States
Barbara Pui Chan
University of Hong Kong Department of Mechanical Engineering, Hong Kong, Hong Kong
Kai-ming Chan
The Chinese University of Hong Kong, Prince of Wales Hospital, Department of Orthopaedics & Traumatology, Shatin, N.T., Hong Kong
Zhong-qiang Chen
Peking University Third Hospital, Beijing, China
Cheng-Kung Cheng
BeiHang University School of Biological Science and Medical Engineering, Beijing, China
Jack Chun-yiu Cheng
The Chinese University of Hong Kong, Prince of Wales Hospital, Department of Orthopaedics & Traumatology, Shatin, N.T.Hong Kong SAR, Hong Kong
Ke-rong Dai
Shanghai 9th Peoples Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China
Yue Ding
Sun Yat-Sen University, Guangzhou, China
Freddie H. Fu
University of Pittsburgh Department of Orthopaedic Surgery, Pittsburgh, Pennsylvania, United States
Xiao-Bing Fu
Fourth Medical Center of PLA General, Beijing, China
Stuart B. Goodman
Stanford University Department of Orthopaedic Surgery, Redwood City, California, United States
Xiaosong Gu
Nantong University, Nantong, China
Yu-Dong Gu
Huashan Hospital Fudan University, Shanghai, China
Shao-keh Hsu
Tungs' Taichung MetroHarbor Hospital, Taichung, Taiwan
Yu-Shu Lai
National Yang Ming University Orthopaedic Device Research Centre, Taipei, Taiwan
Ping-Chung Leung
Centre for Clinical Trials on Chinese Medicine, Shatin, Hong Kong
Lars Lidgren
Skåne University Hospital Lund, Lund, Sweden
Shi-bi Lu
Chinese PLA General Hospital Department of Orthopaedics, Beijing, China
Peter Ma
University of Michigan Department of Materials Science and Engineering, University of Michigan, Ann Arbor, Michigan, USA
Guo-xian Pei
Xijing Hospital, Xian, China
Stephan M. Perren †
AO Foundation, Davos Platz, Switzerland
Gui-xing Qiu
Peking Union Medical College Hospital, Beijing, China
Rocky S. Tuan
Chinese University of Hong Kong, New Territories, Hong Kong
Man-yi Wang
Beijing Jishuitan Hospital and Fourth Medical College of Peking University Department of Radiology, Beijing, China
Yan Wang
Chinese PLA General Hospital, Beijing, China
Zheng-guo Wang
Army Medical University, Chongqing, China
Stuart Weinstein
University of Iowa Department of Orthopaedics and Rehabilitation, Iowa City, Iowa, United States
Savio L-Y Woo
University of Pittsburgh Musculoskeletal Research Center, Pittsburgh, Pennsylvania, United States
Xingdong Zhang
National Engineering Research Center for Biomaterials, Chengdu, China
Yingze Zhang
Hebei Medical University Third Affiliated Hospital, Shijiazhuang, China
Honorary Editor-in-Chief
Kai-ming Chan
The Chinese University of Hong Kong, Prince of Wales Hospital, Department of Orthopaedics & Traumatology, Shatin, N.T., Hong Kong
Ke-rong Dai
Shanghai 9th Peoples Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China
Editor Emeritus
Chih-Hwa Chen
Taipei Medical University Department of Orthopaedic Surgery, Taipei City, Taiwan
Xiang-Dong Guo
Columbia University Department of Biomedical Engineering, New York, United States