Journal of Clinical Medicine (ISSN 2077-0383) is an international, peer-reviewed, open access journal on clinical and pre-clinical research. It publishes article types including Research Papers, Reviews, Editorials, Communications, etc. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. The full experimental details must be provided so that the results can be reproduced.

There is, in addition, a unique feature of this journal: it accepts studies showing meaningful but negative results. While there are many journals that focus on clinical studies, only a few of them actively accept negative results. As a result, most negative data end up not being in the public domain even if the data were meaningfully negative and the study well designed. By accepting those negative results, our journal encourages scientists to share those data so that they would not need to repeat the experiments that somebody else has already carried out.

Subject Areas
This journal covers all topics related to clinical and pre-clinical practices. Topics of interest include (but are not limited to):

Cardiology
Gastroenterology & Hepatopancreatobiliary Medicine
Clinical Neurology
Oncology
Orthopedics
Endocrinology & Metabolism
Nephrology & Urology
Epidemiology & Public Health
Stomatology
Pulmonology
Ophthalmology
Obstetrics & Gynecology
Immunology
Hematology
Clinical Psychology & Psychiatry
Otolaryngology
Dermatology
Clinical Pharmacology

Editorial Board
Editorial Board
Anesthesiology Section
Cardiology Section
Clinical Cytology Section
Clinical Neurology Section
Clinical Psychology Section
Dermatology Section
Emergency Medicine Section
Endocrinology & Metabolism Section
Epidemiology & Public Health Section
Gastroenterology & Hepatopancreatobiliary Medicine Section
Hematology Section
Immunology Section
Infectious Diseases Section
Molecular Diagnostics Section
Nuclear Medicine & Radiology Section
Nephrology & Urology Section
Obstetrics & Gynecology Section
Oncology Section
Ophthalmology Section
Orthopedics Section
Otolaryngology Section
Pharmacology Section
Psychiatry Section
Pulmonology Section
Vascular Medicine Section
Stomatology Section
Editors (24)
Prof. Dr. Emmanuel Andrès E-Mail Website 
Editor-in-Chief
Department of Internal Medicine, Diabetes and Metabolic Diseases, University Hospital of Strasbourg, 1 Porte de l'Hôpital, 67 091 Strasbourg Cedex, France
Tel. 33388115066 
Interests: benignes hematological diseases: neutropenia, anemia and thrombocytopenia related to nutritional disorders, immunological disorders, drugs, infectious diseases; malignant hematological diseases in elderly patients: myeloma, lymphocytic chronic leukemia; autoimmune disorders; orphan metabolic diseases: gaucher, fabry's disease; cationic antimicrobial peptides: human applications, role in human diseases; human sounds analysis, medical devices and telemedicine
Dr. Norihiro Kokudo * E-Mail Website 
Section Editor-in-Chief


National Center for Global Health & Medicine, Shinjyuku Ku, 1-21-1 Toyama, Tokyo 1628655, Japan
Interests: surgical treatment of HCC; colorectal liver metastases; liver transplantation; liver cancer surgery
* Epidemiology & Public Health 
Dr. Sukhwinder Singh Sohal * E-Mail Website 
Section Editor-in-Chief


Respiratory Translational Research Group, Department of Laboratory Medicine, College of Health and Medicine, University of Tasmania, Launceston, TAS 7248, Australia
Interests: chronic obstructive pulmonary disease (COPD); asthma; idiopathic pulmonary fibrosis (IPF); lung cancer; airway remodeling; effects and mechanisms of inhaled corticosteroids (ICS); effects of e-cigarettes and IQOS; mechanisms of respiratory infections and inflammation; smoking cessation and air pollution
* Pulmonology 
Prof. Dr. Sylvia Lee-Huang * E-Mail Website 
Section Editor-in-Chief


Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA
Interests: mitochondria; viral infection; biomarkers; anti-HIV, anti-cancer, anti-obesity agents; regulation of gene expression; small RNAs; human erythropoietin; interactions of proteins and nucleic acids; molecular modeling; bioinformatics; live-cell real time imaging
* Molecular Diagnostics 
Prof. Dr. Alberto Signore * E-Mail 
Section Editor-in-Chief


Department of Surgical-Medical Sciences and Translational Medicine, University of Rome “Sapienza”, Rome, Italy
Interests: nuclear medicine; infection imaging; inflammation imaging; thyroid cancer imaging; pre-clinical imaging; imaging immuno-therapy; imaging autoimmune diseases
* Nuclear Medicine & Radiology 
Special Issues and Collections in MDPI journals
Dr. Hirofumi Noguchi * E-Mail Website 
Section Editor-in-Chief


Department of Regenerative Medicine, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan
Interests: pancreatic islet transplantation; islet regeneration; ES/iPS cells; pancreatic stem/progenitor cells; mesenchymal stem cells
* Clinical Cytology 
Special Issues and Collections in MDPI journals
Prof. Dr. Clara Ionescu * E-Mail Website 
Section Editor-in-Chief


1. Research lab on Dynamical Systems and Control, Faculty of Engineering and Architecture, Ghent University, Ghent, Belgium
2. Member EEDT core lab on Decision and Control, of Flanders Make Consortium, Belgium
Interests: Industrial process control; Multivariable control; Fractional impedance devices; Fractional order control; Predictive control
* Anesthesiology 

Prof. Dr. Massimo Terzolo * E-Mail Website 
Section Editor-in-Chief


Department of Clinical and Biological Sciences, San Luigi Hospital, University of Turin, Regione Gonzole, 10, 10043 Orbassano, Italy
Interests: adrenal diseases; adrenal tumors; Cushing’s syndrome; pituitary diseases; acromegaly
* Endocrinology & Metabolism 
Prof. Dr. Maciej Banach * E-Mail Website 
Section Editor-in-Chief


University of Zielona Góra, Cardiovascular Research Center, Zielona Gora, Poland
Interests: hypertension; lipid disorders; dyslipidemia therapy; new drugs in cardiovascular disease therapy
* Cardiology 
Prof. Dr. Eng Ooi * E-Mail Website 
Section Editor-in-Chief


1. Head of the Otolaryngology Head and Neck Surgery Unit at Flinders Medical Centre, Adelaide 5001, Australia
2. Associate Professor, College of Medicine and Public Health, Flinders University, Adelaide 5001, Australia
Interests: sinusitis; immunology; rhinitis; sleep apnoea; oncology and carcinogenesis; airway and voice disorders; surgical education and simulation
* Otolaryngology 
Special Issues and Collections in MDPI journals 
Prof. Dr. Roland Bingisser * E-Mail Website 
Section Editor-in-Chief


Emergency Department, Hospital Basel, University of Basel, Petersgraben 2, 4031 Basel, Switzerland
Interests: emergency medicine; geriatric patients; nonspecific symptoms
* Emergency Medicine 
Dr. Kent Doi * E-Mail Website 
Section Editor-in-Chief


Department of Acute Care Medicine, University of Tokyo, Tokyo, Japan
Interests: emergency medicine; critical care medicine; intensive care medicine; fluorescence microscopy; cell biology; molecular biology; neuroscience; acute kidney injury and sepsis
* Nephrology & Urology 
Prof. Dr. Olivier Morel * E-Mail Website 
Section Editor-in-Chief


Interventional Cardiology Department, University of Strasbourg, 67081 Strasbourg, France
Interests: thrombosis; acute coronary syndrome; platelet; chronic kidney disease; senescence; bleedings; aortic stenosis; TAVR; microparticles; endothelium
* Vascular Medicine 
Prof. Dr. Lindsay A. Farrer * E-Mail Website 
Section Editor-in-Chief


Departments of Medicine (Biomedical Genetics), Neurology, Ophthalmology, Epidemiology, and Biostatistics, Boston University Schools of Medicine and Public Health, Boston, MA, USA
Interests: clinical trials; epigenetics; genomics; angiogenesis; personalized and precision medicine; metabolomics; proteomics; gene expression; extracellular RNA; disease mechanism; induced pluripotent stem cells; primary cell lines; organoids; imaging; phenotyping; in vivo and in vitro models of AMD; AMD and diseases with overlapping pathophysiology; big data
* Clinical Neurology 
Special Issues and Collections in MDPI journals
Prof. Michele Roccella * E-Mail Website 
Section Editor-in-Chief


1. Coordinator of the School of Specialization in Child Neuropsychiatry, University of Palermo, Italy;
2. Department of Psychology, Educational Science and Human Movement, University of Palermo, Palermo, Italy
Interests: autism spectrum disorders and rare genetic syndromes; autistic spectrum disorder and epilepsy; autistic spectrum disorder and intervention and treatment methods
* Clinical Psychology 
Special Issues and Collections in MDPI journals 
Prof. Dr. Icro Maremmani * E-Mail Website 
Section Editor-in-Chief


Vincent P. Dole Dual Disorder Unit, Department of Neurosciences, Santa Chiara University Hospital, University of Pisa, Via Roma, 67 56126 Pisa, Italy
Interests: substance use disorders and their treatment; opioid dependence; alcoholism and to agonist treatments; dual diagnosis patients; temperamental traits of normal subjects; psychiatric patients; substance abuser patients; heroin addiction; dual disorders; psychopharmacology
* Psychiatry 
Special Issues and Collections in MDPI journals
Prof. Dr. Hidekazu Suzuki * E-Mail Website 
Section Editor-in-Chief


Department of Gastroenterology and Hepatology, Tokai University School of Medicine, 143 Shimokasuya, Isehara city, Kanagawa 259-1193, Japan
Interests: helicobacter pylori; reflux esophagitis; gastroesophageal reflux disease (GERD); peptic ulcer; gastric cancer; functional dyspepsia; constipation
* Gastroenterology & Hepatopancreatobiliary Medicine 
Prof. Dr. Gianrico Spagnuolo * E-Mail Website 
Section Editor-in-Chief


Department of Neuroscience, Reproductive and Odontostomatological Sciences University of Naples "Federico II", Naples, Italy
Interests: dental materials; dental surgery; restorative dentistry and endodontics
* Stomatology 
Special Issues and Collections in MDPI journals
Prof. Dr. Peter Choong * E-Mail Website 
Section Editor-in-Chief


Hugh Devine Professor of Surgery, Department of Surgery, University of Melbourne, Melbourne, Australia
Interests: arthroplasty; outcomes; trials; health economics; infection; tissue engineering; oncology; tumors; hip; knee
* Orthopedics 
Prof. Dr. Margaret M. DeAngelis * E-Mail Website 
Section Editor-in-Chief


Department of Ophthalmology, Department of Population Health Sciences, University of Utah School of Medicine, Department of Pharmacotherapy, School of Pharmacy, Salt Lake City, UT 84132, USA
Interests: clinical trials; epigenetics; genomics; angiogenesis; personalized and precision medicine; metabolomics; proteomics; gene expression; extracellular RNA; disease mechanism; induced pluripotent stem cells; primary cell lines; organoids; imaging; phenotyping; in vivo and in vitro models of AMD; AMD and diseases with overlapping pathophysiology; big data
* Ophthalmology 
Special Issues and Collections in MDPI journals
Dr. Maria Lina Tornesello * E-Mail Website 
Section Editor-in-Chief


Department of Translational Research, Istituto Nazionale Tumori, IRCCS, Fondazione Pascale, Naples, Italy
Interests: viral oncology; human papillomavirus; genital cancer; oropharyngeal cancer; gene mutation; single nucleotide polymorphisms
* Oncology 
Special Issues and Collections in MDPI journals
Prof. Dr. Eyal Sheiner * E-Mail Website 
Section Editor-in-Chief


Department of Obstetrics and Gynecology, Soroka University Medical Center, Israel
Interests: obstetrics; high risk pregnancy; clinical studies; placental abruption; placenta previa; pregnancy as a window of opportunity to detect long-term diseases; obesity in pregnancy; maternal-fetal medicine; perinatal outcome
* Obstetrics & Gynecology 
Prof. Dr. Sergio Rutella * E-Mail Website 
Section Editor-in-Chief


College of Science and Technology, Nottingham Trent University, Clifton Campus, Nottingham, NG11 8NS, UK
Interests: acute myeloid leukemia; immunotherapy; cancer genomics; cancer immunology; hematological malignancies
* Hematology 
Special Issues and Collections in MDPI journals
Prof. Dr. Masutaka Furue * E-Mail Website 
Section Editor-in-Chief


Kyushu University, Department of Dermatology, Fukuoka, Japan
Tel. +81-92-642-5581 
Interests: atopic dermatitis; psoriasis; immundermatology; melanoma, dioxins
* Dermatology 
Special Issues and Collections in MDPI journals
Editorial Board Members (311)
Dr. Samad Ahadian E-Mail Website 


University of California-Los Angeles (UCLA), Los Angeles, CA 90095, USA
Interests: muscle tissue engineering; cardiac tissue regeneration; antimicrobial devices; hydrogels; nanobiomaterials; bioprinting; stem cell engineering
Prof. Dr. Francesco Albano E-Mail 


University of Bari "Aldo Moro" School of Medicine, Policlinico Hospital, Piazza Giulio Cesare 11-70124 Bari, Italy
Interests: molecular pathogenesis of myeloid and lymphoid neoplasms; minimal residual disease in hematologic malignancies; genomic studies applied to the hematologic malignancies
Dr. Ibrahim T. Aldoss E-Mail Website 


Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA
Interests: acute lymphoblastic leukemia; acute myeloid leukemia; allogeneic hematopoietic cell transplantation for acute leukemia
Dr. Radica Alicic E-Mail Website 


Providence Medical Research Center, Providence Health Care, Spokane, WA, USA
Interests: diabetic kidney disease; diabetes management in diabetic kidney disease; diabetes management in hospitalized patients with diabetic kidney disease; sodium glucose co-transporter 2 inhibitors (SGLT-2) and chronic kidney disease; glucagon-like peptide receptor agonists (GLP-1 receptor agonists); chronic kidney disease
Dr. Catherine J. Andersen E-Mail Website 


Department of Biology, Fairfield University, Fairfield, CT, USA
Interests: lipid metabolism; lipoproteins; inflammation; immunity; obesity; functional foods; human nutrition; lipoprotein metabolism; HDL; cholesterol; immune function
Special Issues and Collections in MDPI journals:
Special Issue in Nutrients: Lipid Metabolism in Inflammation and Immune Function
Dr. Sebastiano Andò E-Mail Website 


Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata Di Rende, Italy
Interests: obesity; breast cancer; tumor microenvironment; nuclear receptors; aromatase; endocrine related cancers; endocrine resistance in breast cancer
Dr. Francesco Angelini E-Mail Website 


Department of Experimental and Clinical Pharmacology, IRCCS Centro di Riferimento Oncologico, Aviano, Italy
Interests: stem cell; cadiac progenitor cells; cardiac regeneration; tissue engineering; exosomes; pharmacogenomics; breast cancer
Prof. Dr. Tommaso Angelone E-Mail Website 


Lab of Cellular and Molecular Cardiac Patho-physiology, Departmrnt of Biology, Ecology and Earth Sciences, University of Calabria, 87036, Arcavacata di Rende (CS), Italy
Interests: cardioprotection; myocardial ischemia-reperfusion injury; cardiotoxicity; hypertension; cardiometabolic syndrome; intracellular signaling; chromogranins; selenoproteins
Prof. Dr. Bruno Annibale E-Mail Website 


Sapienza University School of Medicine, University Hospital Sant'Andrea, Roma, Italy
Interests: precancerous gastric conditions; autoimmune atrophic gastritis; neuroendocrine gastrointestinal tumors; recently diverticular disease and its complications
Prof. Dr. Sandro Ardizzone E-Mail Website 


Gastrointestinal Unit, ASST Fatebenefratelli Sacco - Department of Biochemical and Clinical Sciences "L. Sacco", University of Milan, Milano 20157, Italy
Interests: IBD; therapy; immunomodulation; biologic therapy; cell-based therapy
Special Issues and Collections in MDPI journals:
Special Issue in Journal of Clinical Medicine: Ulcerative Colitis: Current and Emerging Treatment Strategies