Clinical Epidemiology is an international, peer reviewed, open access journal. Clinical Epidemiology is primarily focused on research on clinical questions, and on the application of epidemiological principles and questions relating to patients and clinical care in terms of prevention, diagnosis, prognosis, and treatment.

Specific topics covered in the journal include:

Use of electronic medical patient records
Routine health care data, especially as applied to the safety of medical interventions
Clinical utility of diagnostic procedures and screening
Understanding short- and long-term clinical course of diseases
Prognostic and predictive markers
Clinical epidemiological and biostatistical methods
Systematic reviews
Secondary and tertiary prevention
Clinical Epidemiology welcomes papers covering these topics in the form of original research, reviews, and descriptions of international databases.