Trials encompasses all aspects of the performance and findings of randomized controlled trials in human health. We publish articles on general trial methodology and research into trial processes, as well as study protocols and statistical analysis plans for randomised controlled trials, commentaries and traditional results papers - regardless of outcome or significance of findings.

Our aim is to promote transparency in the reporting of randomised trials and build an evidence base that will help inform the design and reporting of future trials. Within this remit, we consider articles or study protocols assessing aspects of the design, conduct or reporting of trials, as well as assessment and evaluation of lessons learnt from past trials, including those that were prematurely ended. We advocate for the collective success for trials and the importance of linking publications together (the thread of evidence).

To facilitate complete and transparency reporting of research, Trials does not ask authors to adhere to strict word limits. We request that authors provide the detail required to make the research replicable. We ask that authors communicate not only all outcome measures, as well as varying analyses and interpretations, but also in-depth descriptions of what they did and what they learnt. This sharing of direct experience is fundamental to improving the quality and conduct of trials worldwide.

Trials aims to experiment with, and refine, innovative approaches to improving communication about randomized controlled trials. We are keen to move beyond publishing traditional trial results articles (although these are included), and we believe this journal represents an exciting opportunity to advance the science and reporting of trials.

Research
Methodology
Review
Study protocol
Commentary
Letter
Update

Editors-in-Chief
Jeremy Grimshaw, Ottawa Health Research Institute, Canada  
Peter Jüni, University of Toronto, Canada
Tianjing Li, University of Colorado Denver, USA 
Shaun Treweek, University of Aberdeen, UK

Founding Editor
Douglas Altman

Senior Editors
Matthias Briel, University of Basel, Switzerland
An-Wen Chan, University of Toronto, Canada
Karla Hemming, University of Birmingham, UK
Will Meurer, University of Michigan, USA
Matt Sydes, University College London, UK

Associate Editors
Victoria Allgar, University of York, UK
Catherine Arundel, University of York, UK
Kerry Avery, University of Bristol, UK
Sunil Badve, The George Institute for Global Health, Australia
Eivind Berge, Oslo University Hospital, Norway
Zhaoxiang Bian, Hong Kong Baptist University, Hong Kong
Jean Joel Bigna, University of Paris Sud XI, France
Elena Bignami, University of Parma, Italy 
Oscar Bortolami, Syneos Health, UK 
Stig Brorson, University of Copenhagen, Denmark
Claudia Buntrock, University Erlangen-Nuremberg, Germany
Félix Caballero, Universidad Autónoma de Madrid, Spain
Alison Calear, The Australian National University, Australia
Alexandre Biasi Cavalcanti, HCor Research Institute, Brazil
Wai Tong Chien, The Chinese University of Hong Kong, Hong Kong
Babak Choodari-Oskooei, University College London, UK
Vincent Chung, The Chinese University of Hong Kong, Hong Kong
Marie Ciarleglio, Yale University, USA
Sarah Cockayne, University of York, UK
Chris Coffey, The University of Iowa, USA
Andrew Cook, University of Southampton, UK
Catherine Crespi, University of California, Los Angeles, USA
Dawn Craig, University of Newcastle, UK 
Suzie Cro, Imperial College London, UK
Sarah Dean, University of Exeter, UK
Munyaradzi Dimairo, University of Sheffield, UK
Gheorghe Doros, Boston University, USA
Emily Dressler, Wake Forest School of Medicine, USA
Joel Dubin, University of Waterloo, Canada 
Andrew Duckworth, University of Edinburgh, UK
Susan Dutton, University of Oxford, UK
Elham Emami, Université de Montréal, Canada
Ann Ervin, Johns Hopkins Bloomberg School of Public Health, USA
Caroline Fairhurst, University of York, UK
Joel Gagnier, University of Michigan, USA
Kimberley Goldsmith, King's College London, UK
Dario Gregori, University of Padova, Italy
Christopher Halloran, University of Liverpool, UK 
Patrick Harris, University of Queensland, Australia
Angela Hassiotis, University College London, UK
Dietrich Haubenberger, National Institutes for Health, USA
Lars Hemkens, Basel Institute for Clinical Epidemiology and Biostatistics, Switzerland
Daniela Hesse, Academic Centre for Dentistry Amsterdam, Netherlands
Thomas Hiemstra, University of Cambridge, UK
Tammy Hoffman, Bond University, Australia
Richard Holubkov, University of Utah Health, USA
Richard Hooper, Queen Mary University of London, UK
Tazeen Jafar, Duke-NUS Medical School, Singapore
Megan Jensen, University of Newcastle, UK
Benjamin Kasenda, Basel Institute for Clinical Epidemiology & Biostatistics, Switzerland
Annet Kleiboer, VU University Amsterdam, Netherlands
Angelos Kolias, University of Cambridge, UK
Linda Kwakkenbos, Radboud University, Netherlands
Paul Leighton, University of Nottingham, UK
Erik Lenguerrand, University of Bristol, UK
Ai-Hsien Li, Far Eastern Memorial Hospital, Taiwan
Teresa Liu-Ambrose, University of British Columbia, Canada
Yuliya Lokhnygina, Duke University, USA
Amanda López Picado, San Carlos University Hospital, Spain
Steven MacLennan, University of Aberdeen, UK
Dylan MacKay, University of Manitoba, Canada
Julia Mader, Medical University of Graz, Austria 
Ranjit Manchanda, Queen Mary University of London, UK
Adrian Mander, Cardiff University, UK
Amelia Marques, Universidade de São Paulo, Brazil
Evan Mayo-Wilson, Johns Hopkins Bloomberg School of Public Health, USA
Doreen McClurg, Glasgow Caledonian University, UK
Caroline McIntosh, NUI Galway, Ireland
Christoph Michalski, Martin Luther University Halle-Wittenberg, Germany  
Ali Modabber, University of Aachen, Germany
Ann Merete Møller, Herlev University Hospital, Denmark
Bronwyn Myers, South African Medical Research Council, South Africa
Mona Nabulsi, American University of Beirut, Lebanon
Felix Nickel, University of Heidelberg, Germany 
Daniel Niederer, Goethe University Frankfurt, Germany
Kerry-Ann O'Grady, Queensland University of Technology, Australia
Emily Peckham, University of York, UK
Claudia Pedroza, The University of Texas, USA
Patrick Phillips, University of California, San Francisco, USA
Jochen G Raimann, Renal Research Institute, USA
Rangasamy Ramanathan, University of Southern California, USA
Yousef Rezaei, Rajaie Cardiovascular Medical and Research Center, Iran
Claire Rickard, Griffith University, Australia
Matthew Roberts, Monash University, Australia
Ines Rombach, University of Oxford, UK
Vincenzo Russo, University of Campania, Italy
Bobbi Scherer, Johns Hopkins Bloomberg School of Public Health, USA 
JD Schwalm, McMaster University, Canada
Shahzad Shaefi, Harvard Medical School, USA
Haleema Shakur-Still, London School of Hygiene & Tropical Medicine, UK
Lisa Shaw, University of Newcastle, UK
Pamela Shaw, University of Pennsylvania, USA
Laura Sheard, Bradford Teaching Hospitals NHS Foundation, UK 
Jasvinder Singh, Mayo Clinic, USA
Alice Sitch, University of Birmingham, UK
Claire Snowdon, London School of Hygiene & Tropical Medicine, UK
Benjamin Speich, Centre for Statistics in Medicine, UK
Jessica Spence, Population Health Research Institute, Canada
Christopher Sudfeld, Harvard T.H. Chan School of Public Health, USA
Tamás Szakmany, Cardiff University, UK
David Tappin, University of Glasgow, UK
Puvanendran Tharmanathan, University of York, UK
Lorenzo Trippa, Harvard T.H. Chan School of Public Health, USA
Liz Turner, Duke Global Health Institute, USA 
Victoria Vickerstaff, University College London, UK
Xue-Qiang Wang, Shanghai University of Sport, China
James Wason, Newcastle University, UK
Charles Weijer, University of Western Ontario, Canada
Nefyn Williams, University of Liverpool, UK
Mingxiao Yang, Chengdu University of Traditional Chinese Medicine, China
Lihui Zhao, Northwestern University, USA
Editorial Board
Fernando Althabe, Institute for Clinical Effectiveness and Health Policy, Argentina 
Jesse Berlin, Johnson & Johnson Pharmaceutical Research and Development, USA 
Marion Campbell, University of Aberdeen, UK 
Jonathan A Cook, University of Oxford, UK 
Ralph D'Agostino, Boston University, USA
Janet Dunn, CRC Trials Unit, UK 
Diana Elbourne, London School of Hygiene & Tropical Medicine, UK 
Susan Ellenberg, University of Pennsylvania, USA 
Leif Erhardt, Lund University, Sweden 
Dean Fergusson, Ottawa Hospital Research Institute, Canada
Toshiaki Furukawa, Kyoto University, Japan 
Paul Glasziou, University of Oxford, UK 
Christian Gluud, Centre for Clinical Intervention Reseach, Denmark 
Rod Jackson, University of Auckland, New Zealand 
Igor Karp, Western Ontario, Canada
Nancy King, Wake Forest School of Medicine, USA
Simon Lewin, Norwegian Knowledge Centre for the Health Services, Norway 
Steff Lewis, Edinburgh University, UK 
Thomas Lumley, University of Washington, USA 
Finlay McAlister, University of Alberta, Canada 
Victor Montori, Mayo Clinic, USA 
Ian Needleman, UCL Eastman Dental Institute, UK
Philip Pallmann, Cardiff University, UK
Max Parmar, University College London, UK 
Tim Peto, Oxford University, UK 
Gilda Piaggio, World Health Organization, Switzerland 
Bertram Pitt, University of Michigan School of Medicine, USA 
Stuart Pocock, London School of Hygiene and Tropical Medicine, UK 
Philippe Ravaud, The French Cochrane Centre, France 
David Schriger, University of California, Los Angeles, USA 
Kenneth Schulz, FHI 360, USA
Monica Taljaard, University of Ottawa, Canada 
Lehana Thabane, St. Joseph's Healthcare Hamilton, Canada  
David Torgerson, York University, UK 
Luke Vale, University of Aberdeen, UK 
Taixiang Wu, West China Hospital, Sichuan Uni, China