NMR in Biomedicine is a journal devoted to the publication of original full-length papers, rapid communications and review articles describing the development of magnetic resonance spectroscopy or imaging methods or their use to investigate physiological, biochemical, biophysical or medical problems. Topics for submitted papers should be in one of the following general categories: (a) development of methods and instrumentation for MR of biological systems; (b) studies of normal or diseased organs, tissues, cells or body fluids; (c) diagnosis or treatment of disease. Reports may cover work on patients or healthy human subjects, in vivo animal experiments, studies of isolated organs or cultured cells, analysis of tissue extracts or body fluids, NMR theory, experimental techniques, or instrumentation. The Journal will not accept any papers that deal solely with the routine application of established MR imaging and post-processing methods in clinical studies. NMR in Biomedicine will accept for review manuscripts that focus on the use of MRI contrast agents in practical applications, but not those that are primarily concerned with the development, synthesis or ex vivo testing of contrast agents.