Systems biology is an integrative discipline that seeks to explain the properties and behaviour of complex biological systems in terms of their components and their interactions.

Molecular Systems Biology is a peer-reviewed open access journal that publishes high-quality research in the fields of systems biology, synthetic biology and systems medicine.

Topics falling within the scope of the journal include, but are not limited to:

integrative genome-scale biology 
quantitative biology
computational biology 
metabolic and regulatory networks 
evolution of genomes and biological networks
clinical and translational systems biology 
synthetic biology and genome-scale biological engineering
Molecular Systems Biology publishes research articles as full-length Articles or short Reports. The journal also publishes Methods, Reviews, News & Views, Opinions, Correspondences, Commentaries and Editorials.