The European Journal of Clinical Pharmacology publishes original papers on all aspects of clinical pharmacology and drug therapy in humans. Manuscripts are welcomed on the following topics: therapeutic trials, pharmacokinetics/pharmacodynamics, pharmacogenetics, drug metabolism, adverse drug reactions, drug interactions, all aspects of drug development, development relating to teaching in clinical pharmacology, pharmacoepidemiology, and matters relating to the rational prescribing and safe use of drugs. Methodological contributions relevant to these topics are also welcomed.

Data from animal experiments are accepted only in the context of original data in man reported in the same paper. EJCP will only consider manuscripts describing the frequency of allelic variants in different populations if this information is linked to functional data or new interesting variants. Highly relevant differences in frequency with a major impact in drug therapy for the respective population may be submitted as a letter to the editor.

Straightforward phase I pharmacokinetic or pharmacodynamic studies as parts of new drug development will only be considered for publication if the paper involves

a compound that is interesting and new in some basic or fundamental way, or
methods that are original in some basic sense, or
a highly unexpected outcome, or
conclusions that are scientifically novel in some basic or fundamental sense.
Straightforward descriptive data in drug utilization will only be considered if more than one geographical area is studied and if a scientific hypothesis is tested or an intervention carried out. Descriptive data in drug utilization can however be quite useful in a more local setting. Again, if conceptually new methods, analysis, or ways of reasoning are involved, this would elicit greater interest from the international scientific community. In such a case, we would welcome submission to the EJCP and evaluate the paper according to standard procedures.

The Journal also accepts review articles on various topics related to drug action in man. Debate on controversial issues is also encouraged, usually in the form of a letter to the editor that comments on a paper published in the Journal. Case reports on new findings or a new understanding of a mechanism of action should usually also be submitted in the form of a letter to the editor.

Coordinating Editor
Rune Dahlqvist
Division of Clinical Pharmacology
University Hospital
90185 Umeå
Sweden

E-mail: Rune.Dahlqvist@pharm.umu.se

Managing Editors 
Uwe Fuhr, Cologne
Emilio J. Sanz, La Laguna
David J.P. Williams, Dublin
Markus Zeitlinger, Vienna
Reviews Editor
Uwe Fuhr, Cologne
Advisory Editors
Karel Allegaert, Leuven 
Janne Backman, Helsinki 
Julio R. Benítez, Badajoz
Joseph S. Bertino Jr, Albany
Maurizio Bonati, Milan
Ylva Böttiger, Huddinge
Alasdair M. Breckenridge, Liverpool
Ingolf Cascorbi, Kiel
Imtiaz Choonara, Derby
Balram Chowbay, Singapore
Fan K. Chung, London
Uwe Christians, Denver
Marja-Liisa Dahl, Stockholm
Rafael Dal-Ré, Madrid
Vita Dolzan, Ljubljana
Johan Fastbom, Stockholm
Robin E. Ferner, Birmingham
Alberg Figueras, Barcelona
Sarah Foley, Cork
Sebstian Frechen, Köln
Takahisa Furuta, Hamamatsu
Andrea Gaedigk, Kansas City
Silvio Garattini, Milan
Walter E. Haefeli, Heidelberg
Staffan Hägg, Linköping
Job Harenberg, Mannheim
Martin Hellmich, Köln
Georg Hempel, Münster
Martin Henriksson, Linköping
Christoph Hiemke, Mainz
Nick Holford, Auckland
Kalle Hoppu, Helsinki
Alexander Jetter, Zurich
Frieder Keller, Ulm
Stephan Krähenbühl, Basel
Joan R. Laporte, Barcelona
Andreas Lindauer, Oss
Jörn Lötsch, Frankfurt
Arduino A. Mangoni, Bedford Park
Patricia McGettigan, London
Juan Merlo, Malmö 
John Miners, Adelaide
Klaus Mörike, Tübingen
Nicola Montanaro, Bologna
Jean-Louis Montastruc, Toulouse
Nicholas Moore, Bordeaux
Domenico Motola, Bologna
Pertti J. Neuvonen, Helsinki
Hedvig M.E. Nordeng, Oslo
Stefan Oswald, Greifswald
Roberto Raschetti, Roma
Christoph Ritter, Greifswald
Cristín Ryan, Dublin
Laura J. Sahm, Cork
Jörn Schneede, Umeå
Folke Sjöqvist, Huddinge
Olav Spigset, Trondheim
Edoardo Spina, Messina
Julia C. Stingl, Bonn
John Stinson, Crumblin
J.J. Swen, Leiden
Petra Thürmann, Wuppertal
Dietmar Trenk, Bad Krozingen
Ellen Vinge, Lund
Susanna M. Wallerstedt, Gothenburg
Tom Walley, Liverpool
Matthew Walters, Glasgow
William S. Waring, York
Martin Wehling, Mannheim
Björn Wettermark, Stockholm
Nick J. White, Oxford
Ken W. Woodhouse, Cardiff
Ümit Yasar, Ankara
Hong-Hao Zhou, Changsha