As the discipline of biochemistry and molecular biology have greatly advanced in the last quarter century, significant contributions have been made towards the advancement of general medicine, genetics, immunology, developmental biology, and biophysics. Investigators in a wide range of disciplines increasingly require an appreciation of the significance of current biochemical and molecular biology advances while, members of the biochemical and molecular biology community itself seek concise information on advances in areas remote from their own specialties.

Critical Reviews in Biochemistry and Molecular Biology believes that well-written review articles prove an effective device for the integration and meaningful comprehension of vast, often contradictory, literature. Review articles also provide an opportunity for creative scholarship by synthesizing known facts, fruitful hypotheses, and new concepts. Accordingly, Critical Reviews in Biochemistry and Molecular Biology publishes high-quality reviews that organize, evaluate, and present the current status of high-impact, current issues in the area of biochemistry and molecular biology.

Topics are selected on the advice of an advisory board of outstanding scientists, who also suggest authors of special competence. The topics chosen are sufficiently broad to interest a wide audience of readers yet focused enough to be within the competence of a single author or group of authors. Authors are chosen based on their activity in the field and their proven ability to produce a well-written publication. Invited authors are encouraged not only to review a field but to put forward their own unique perspective.

Most articles published in the journal are invited. Unsolicited articles are occasionally considered if space is available. Prospective authors should provide a pdf file of the article and a cover letter through the submission system for editorial assessment. Articles are considered and advanced to peer review only if they cover topics of broad interest, are focused on mechanisms, systems, or novel methods related to Biochemistry and Molecular Biology, and are addressed by authors who have made substantial published contributions to the literature being reviewed.