CJASN aims to cement the journal as the leading voice in communicating and influencing advances in clinical nephrology by (1) rapidly and effectively communicating the most important advances in clinical and translational research in nephrology, including innovations in research methods and care delivery; (2) putting these advances in context for future research directions and patient care; and (3) becoming an important voice on every issue that potentially affects the clinical practice of nephrology, particularly in the United States. Original manuscript topic areas include: Acid/Base and Electrolyte Disorders; Acute Kidney Injury and ICU Nephrology; Chronic Kidney Disease; Clinical Nephrology; Cystic Kidney Disease; Diabetes and the Kidney; Genetics; Geriatric and Palliative Nephrology; Glomerular and Tubulointerstitial Diseases; Hypertension; Maintenance Dialysis; Mineral Metabolism; Nephrolithiasis; and Transplantation.