International Journal of Clinical Chemistry and Diagnostic Laboratory Medicine
The Official Journal of the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC)

Clinica Chimica Acta is a high-quality journal which publishes original Research Communications in the field of clinical chemistry and laboratory medicine, defined as the diagnostic application of chemistry, biochemistry, immunochemistry, biochemical aspects of hematology, toxicology, and molecular biology to the study of human disease in body fluids and cells.


The objective of the journal is to publish novel information leading to a better understanding of biological mechanisms of human diseases, their prevention, diagnosis, and patient management. Reports of an applied clinical character are also welcome. Papers concerned with normal metabolic processes or with constituents of normal cells or body fluids, such as reports of experimental or clinical studies in animals, are only considered when they are clearly and directly relevant to human disease. Evaluation of commercial products have a low priority for publication, unless they are novel or represent a technological breakthrough. Studies dealing with effects of drugs and natural products and studies dealing with the redox status in various diseases are not within the journal's scope. Development and evaluation of novel analytical methodologies where applicable to diagnostic clinical chemistry and laboratory medicine, including point-of-care testing, and topics on laboratory management and informatics will also be considered. Studies focused on emerging diagnostic technologies and (big) data analysis procedures including digitalization, mobile Health, and artificial Intelligence applied to Laboratory Medicine are also of interest.

Full-length research articles
Review articles
Brief Reports and Case Reports

Editors-in-Chief
Joris Delanghe
Universitair Ziekenhuis Gent, Gent, Belgium
Alan H. Wu
Zuckerberg San Francisco General Hospital and Trauma Center, San Francisco, California, United States
Reviews Editor
Greg Makowski
Hartford Hospital, Hartford, Connecticut, United States
Editors
Marc De Buyzere
Universitair Ziekenhuis Gent, Gent, Belgium
Ming Guan
Huashan Hospital Fudan University, Shanghai, China
Ching-Wan Lam
University of Hong Kong, Pokfulam, Hong Kong
Statistics Editor
Hans Pottel
KU Leuven Department of Public Health and Primary Care, Leuven, Belgium
Editorial Board
Samir Awadallah
University of Sharjah, Sharjah, United Arab Emirates
Hassan Azzazy
The American University in Cairo, New Cairo, Egypt
Sergio Bernardini
University of Rome Tor Vergata, Roma, Italy
R. Blankenstein
VU University Medical Center Amsterdam, Amsterdam, Netherlands
Claude Bohuon
Paris, France
David Bullock
United Kingdom National External Quality Assessment Service, Sheffield, United Kingdom
Joiza Camargo
Clinics Hospital of Porto Alegre, Porto Alegre, Brazil
E. Cavalier
CHU de Liège, Liege, Belgium
Jaw-Wen Chen
Taipei Veterans General Hospital, Taipei, Taiwan
Chun-Wen Cheng
Chung Shan Medical University, Taichung, Taiwan
Theodore Christopoulos
University of Patras Department of Chemistry, Patras, Greece
Christa Cobbaert
Leiden University Medical Center Department of Cardiology, Leiden, Netherlands
William Coleman
University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States
John Contois, PhD
Laboratory Corporation of America, Burlington, North Carolina, United States
Gyorgy Csako
National Institutes of Health, Bethesda, Maryland, United States
Amitava Dasgupta
University of Texas Health Science Center at Houston, Houston, Texas, United States
Sridevi Devaraj
Baylor College of Medicine, Houston, Texas, United States
James Donnelly
Babson Diagnostics Laboratory Operations, Austin, Texas, United States
Tze Kiong Er
Kaohsiung Medical University, Kaohsiung, Taiwan
Rajiv T. Erasmus
Stellenbosch University, Stellenbosch, South Africa
Philippe Gillery
Reims Champagne-Ardenne University, Reims, France
Ernesto González Reyes
Immunoassay Center, La Habana, Cuba
Peter Hickman
Australian National University, Canberra, Australia
Mario Hirata
University of Sao Paulo, São Paulo, Brazil
Yih-Shou Hsieh
Chung Shan Medical University, Taichung, Taiwan
Akihiro Inazu
Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan
Inho Jo
Korean National Institute of Health Center for Biomedical Sciences, Seoul, Korea, Republic of
Saeed Jortani
University of Louisville, Louisville, Kentucky, United States
Jau-Tsuen Kao
National Taiwan University, Taipei, Taiwan
Ishmael Kasvosve
University of Zimbabwe, Harare, Zimbabwe
Jin Kim
Seoul National University Department of Pathology, Jongno-gu, Korea, Republic of
Gerald Kost
Davis, California, United States
Gert Kostner
Graz University of Technology, Graz, Austria
Maode Lai
Zhejiang University School of Medicine, Hangzhou, China
Michel Langlois
General Hospital Saint-Jan, Brugge, Belgium
Jian-Jun Li
Chinese Academy of Medical Sciences & Peking Union Medical College Fuwai Hospital, Xicheng District, China
Stephen Li
The Sydney Children's Hospitals Network Randwick and Westmead, Westmead, Australia
Masato Maekawa
Hamamatsu University School of Medicine, Hamamatsu, Japan
Q. Meng
University of Texas MD Anderson Cancer Center, Houston, TX, United States
Takashi Miida
Juntendo University, Bunkyo-Ku, Japan
Mathias Müller
Austrian Association for Quality Assurance and Standardization of Medical and Diagnostic Tests, Vienna, Austria
Michele Mussap
University of Cagliari Faculty of Medicine, Cagliari, Italy
Katsuyuki Nakajima
Tokai University School of Medicine Graduate School of Medicine Department of Forensic Medicine, Maebashi, Gunma, Japan
Nobuo Okumura
Shinshu University Graduate School of Health Sciences School of Health Sciences, Matsumoto, Japan
Jorge Ordonez-Llanos
Hospital of the Holy Cross and Saint Paul Clinical Biochemistry Service, Barcelona, Spain
Mauro Panteghini
University of Milan, Milano, Italy
Oscar Perez-Mendez
Ignacio Chavez National Institute for Cardiology, Ciudad de Mexico, Mexico
Tahir Pillay
University of Pretoria, Pretoria, South Africa
Christopher Price
Daglingworth, Cirencester, UK
Kari Pulkki
University of Eastern Finland Unit of Clinical Medicine, KUOPIO, Finland
Pete Rainey
University of Washington, Seattle, Washington, United States
Luis Salazar
University of the Frontier, Temuco, Chile
Nils-Erik Saris
University of Helsinki, Helsinki, Finland
Edson da Silva
Federal University of Santa Catarina, Florianópolis, Brazil
Lawrence Silverman
University of Virginia Department of Public Health Sciences, Charlottesville, Virginia, United States
Patrick Sluss
Massachusetts General Hospital Pathology Service, Boston, Massachusetts, United States
Lori Sokoll
Johns Hopkins University School of Medicine, Baltimore, Maryland, United States
John Toffaletti
Duke University, Durham, North Carolina, United States
Minoru Tozuka
Tokyo Medical and Dental University, Tokyo, Japan
Li-Yu Tsai
Kaohsiung Medical University, Kaohsiung, Taiwan
Bin Wang
Nanjing Medical University, Nanjing, China
Xiaoping Wang
Shaanxi University of Chinese Medicine, Xianyang, China
Philip Wenham
Victoria Hospital, Kirkcaldy, United Kingdom
William Winter
University of Florida, Gainesville, Florida, United States
Steven Wong
Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States
Stuart Woodhead
Invitron Ltd, Monmouth, United Kingdom
Jiaxi Wu
Shanghai Clinical Research Center, Shanghai, China