Bioorganic Chemistry publishes research that addresses biological questions at the molecular level, using organic chemistry and principles of physical organic chemistry. The scope of the journal covers a range of topics at the organic chemistry-biology interface, including: enzyme catalysis, biotransformation and enzyme inhibition; nucleic acids chemistry; medicinal chemistry; natural product chemistry, natural product synthesis and natural product biosynthesis; antimicrobial agents; lipid and peptide chemistry; biophysical chemistry; biological probes; bio-orthogonal chemistry and biomimetic chemistry.

For manuscripts dealing with synthetic bioactive compounds, the Journal requires that the molecular target of the compounds described must be known, and must be demonstrated experimentally in the manuscript. For studies involving natural products, if the molecular target is unknown, some data beyond simple cell-based toxicity studies to provide insight into the mechanism of action is required. Studies supported by molecular docking are welcome, but must be supported by experimental data. The Journal does not consider manuscripts that are purely theoretical or computational in nature.

The Journal publishes regular articles, short communications and reviews. Reviews are normally invited by Editors or Editorial Board members. Authors of unsolicited reviews should first contact an Editor or Editorial Board member to determine whether the proposed article is within the scope of the Journal.



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Editors
Kurt Deshayes, (Editor)
Mark D. Distefano, (Editor-in-Chief)
University of Minnesota, Minneapolis, Minnesota, United States
Lei Fu, (Editor)
Shanghai Jiao Tong University - Fahua Campus, Shanghai, China
Silvia Schenone, (Editor)
University of Genoa, Genova, Italy
Tanaji Talele, (Editor)
Saint John's University Department of Pharmaceutical Sciences, Queens, New York, United States
Editorial Board
Timothy Bugg
University of Warwick, Coventry, United Kingdom
Simone Carradori
Gabriele d'Annunzio University of Chieti and Pescara, Chieti, Italy
Young-Tae Chang
Pohang University of Science and Technology Department of Chemistry, Pohang, Korea, Republic of
Yong-Xiang Chen
Department of Chemistry, Key Laboratory Of Bioorganic Phosphorus Chemistry & Chemical Biology, Ministry of education, Tsinghua University, Beijing, China
Philip Cole
Johns Hopkins University School of Medicine, Baltimore, Maryland, United States
Benjamin F. Cravatt
Scripps Research Institute Skaggs Institute for Chemical Biology, La Jolla, California, United States
Benjamin G. Davis
University of Oxford Chemistry Research Laboratory, Oxford, United Kingdom
Wilfred van der Donk
University of Illinois at Urbana-Champaign, Champaign, Illinois, United States
Debra Dunaway-Mariano
University of New Mexico, Albuquerque, New Mexico, United States
Michael Fitzgerald
Duke University, Durham, North Carolina, United States
Donald Hilvert
Swiss Federal Institute of Technology Zürich Laboratory of Organic Chemistry, Zurich, Switzerland
Eileen Jaffe
Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States
Jaak Järv
University of Tartu, Tartu, Estonia
Sean Kerwin
University of Texas at Austin, Austin, Texas, United States
Ki Hyun Kim
Sungkyunkwan University School of Pharmacy, Suwon, Korea, Republic of
Ronald Kluger
University of Toronto, Toronto, Ontario, Canada
Po-Huang Liang
Academia Sinica, Taipei, Taiwan
Hung-wen Liu
University of Texas at Austin, Austin, Texas, United States
Shahriar Mobashery
Wayne State University, Detroit, Michigan, United States
Govindasamy Mugesh
Indian Institute of Science, Bengaluru, India
Junko Ohkanda
Shinshu University Graduate School of Agriculture Faculty of Agriculture, Kamiina-gun, Japan
Manojit Pal
Dr Reddy's Institute of Life Sciences, Hyderabad, India
Seung Bum Park
Seoul National University CRI Center for Chemical Proteomics, Seoul, Korea, Republic of
Dehua Pei
OHIO STATE UNIVERSITY, Columbus, Ohio, United States
Frank Raushel
Texas A&M University College Station, College Station, Texas, United States
Richard
University at Buffalo Department of Chemistry, Buffalo, New York, United States
Hiroaki Suga
The University of Tokyo, Bunkyo-Ku, Tokyo, Japan
Martin Tanner
The University of British Columbia, Vancouver, British Columbia, Canada
Peter Tipton
University of Missouri, Columbia, Missouri, United States
Tiziano Tuccinardi
University of Pisa Department of Pharmacy, Pisa, Italy
David Vocadlo
Simon Fraser University, Burnaby, British Columbia, Canada
Nick Westwood
University of St Andrews School of Chemistry, St. Andrews, United Kingdom