期刊名称 | ARCHIVES OF TOXICOLOGY ARCH TOXICOL |
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期刊ISSN | 0340-5761 |
期刊官方网站 | http://link.springer.com/journal/204 |
是否OA | 否 |
出版商 | Springer Verlag |
出版周期 | Monthly |
始发年份 | 1974 |
年文章数 | 235 |
最新影响因子 | 4.8(2023) scijournal影响因子 greensci影响因子 |
大类学科 | 小类学科 | Top | 综述 |
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医学2区 | TOXICOLOGY 毒理学1区 | 是 | 否 |
CiteScore排名 | CiteScore | SJR | SNIP | ||
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学科 | 排名 | 百分位 | 5.14 | 1.609 | 1.538 |
Pharmacology, Toxicology and Pharmaceutics Toxicology |
8 / 114 | 93% |
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Environmental Science Health, Toxicology and Mutagenesis |
13 / 117 | 89% |
自引率 | 10.60% |
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H-index | 84 |
SCI收录状况 |
Science Citation Index Science Citation Index Expanded |
官方审稿时间 | |
网友分享审稿时间 | 数据统计中,敬请期待。 |
PubMed Central (PMC) | http://www.ncbi.nlm.nih.gov/nlmcatalog?term=0340-5761%5BISSN%5D |
期刊投稿网址 | https://www.editorialmanager.com/atox/default.aspx |
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收稿范围 |
Additional information Modern toxicology faces several major challenges. Firstly, the available toxicological data are insufficient for a large number of chemicals to which humans are exposed. Because our testing capacities are not sufficient to evaluate each individual compound or even mixtures of compounds in a reasonable time, new, more efficient techniques and testing strategies are required. Secondly, toxicology must keep pace with the rapidly growing knowledge about the molecular mechanisms responsible for adverse health effects because without this knowledge, toxicological risk evaluation will remain incomplete. Therefore, articles examining toxic as well as pathophysiological mechanisms relevant to the mode of action of chemicals on the human and mammalian organism will continue to be a major focus of our journal. Thirdly, advances in "omics" technologies and systems biology approaches have provided fresh insight into the complex interrelationships among the large numbers of factors involved. Therefore in future, a major challenge will be to model biological systems and quantitatively simulate perturbations by toxic substances. Finally, unrealistic expectations by parts of our society, including some politicians, represent a major challenge to toxicology. One particular example is the unrealistic expectation that animal experiments can be replaced by in vitro techniques within a few years, without increasing the risk of adverse consequences for human health. The opinion that virtually all toxicity testing can be conducted in human cell lines or primary cells and the required dose-response relationships can be achieved by pharmacokinetic models is an easy one to have. Unfortunately, being able to experimentally deliver such results is extremely challenging. Authors who have achieved specific progress in this important field of research are particularly encouraged to submit their results to our journal. |
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