Official Journal of EUROTOX

An international journal for the rapid publication of novel reports on a range of aspects of toxicology, especially mechanisms of toxicity.

Toxicology Letters serves as a multidisciplinary forum for research in toxicology. The prime aim is the rapid publication of research studies that are both novel and advance our understanding of a particular area. In addition to hypothesis-driven studies on mechanisms of mammalian toxicity, Toxicology Letters welcomes seminal work in the following areas:
In silico toxicology
Toxicokinetics
Physiologically-based pharmacokinetic (PBPK) modeling
Systems toxicology
Predictive toxicology
3R research in toxicology
New approach methodology (NAMs)
Adverse outcome pathways (AOPs)
Integrated testing strategies


Systematic and narrative reviews and mini-reviews in various areas of toxicology will be published. Clinical, occupational and safety evaluation, hazard and risk assessment, regulatory toxicology, impact on man, animal and environment studies of sufficient novelty to warrant rapid publication will be considered. Toxicology Letters also publishes editorials, commentaries and contemporary issues in toxicology.

The following types of work are not within the scopes of Toxicology Letters:
Ecotoxicology studies
Case studies
Chemoprevention studies
Pharmacological investigations


Authors are advised to follow the ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments; https://arriveguidelines.org/) and the OECD guidance document on Good In Vitro Method Practices (GIVIMP; https://www.oecd.org/env/guidance-document-on-good-in-vitro-method-practices-givimp-9789264304796-en.htm). In vitro or in vivo investigations conducted at concentrations or doses of no relevance to human or animal exposure will not be considered. Routes of exposure other than those relevant to human or animal exposure need to be justified. Assessment of dose-response should be an integral component of any toxicological research report. Unless adequately justified, studies conducted at a single dose level may not be considered. Test materials must be chemically defined and characterized. Investigations of chemically undefined plant extracts or uncharacterized nanoparticles will not be considered.

short reports
mini-reviews
editorials
commentaries
contemporary issues

Editor-in-Chief
Wolfgang Dekant
Julius Maximilians University Wurzburg Department of Toxicology, Versbacher Straße 9, 97078, Wurzburg, Germany, Fax: +49-931-3148865 Phone +49-173-8551041
Co-Editors
Scott Garrett
University of North Dakota School of Medicine and Health Sciences, 501 N. Columbia Road Stop 9037, Grand Forks, North Dakota, ND 58202, United States Email Scott Garrett
Yunbo Li
Campbell University, Buies Creek, 27506-0567, United States, Fax: +1 (910) 814-4921Phone +1 (910) 893-1754 Email Yunbo Li
Angela Mally
Julius Maximilians University Wurzburg Department of Toxicology, Versbacher Straße 9, 97078, Wurzburg, Germany, Fax: +49 931 201 48865 Email Angela Mally
Honorary Founding Editor
Editor Emeritus
James P. Kehrer
University of Alberta Faculty of Pharmacy and Pharmaceutical Sciences, 8613 – 114th St., Edmonton, T6G 2N8, Alberta, Canada
Editorial Board
Jorma Ahokas
RMIT University School of Medical Sciences, Bundoora, Victoria, Australia
Benson Akingbemi
Auburn University Department of Anatomy Physiology and Pharmacology, Auburn, Alabama, United States
Lauren Aleksunes
Rutgers University Ernest Mario School of Pharmacy, Piscataway, New Jersey, United States
Sandy Benoff
Northwell Health Feinstein Institutes for Medical Research, Manhasset, New York, United States
Martin van den Berg
Utrecht University Institute for Risk Assessment Sciences, Utrecht, Netherlands
Matthew Campen
University of New Mexico Department of Pharmaceutical Sciences, Albuquerque, New Mexico, United States
Zhuoxiao Cao
Novo Nordisk China Pharmaceuticals Co Ltd, Beijing, China
William Caudle
Emory University School of Public Health, Atlanta, Georgia, United States
Jan Commandeur
Free University of Amsterdam Division of Molecular and Computational Toxicology, Amsterdam, Netherlands
Mike L. Cunningham
National Toxicology Program, Research Triangle Park, North Carolina, United States
Vincenzo Cuomo
University of Rome La Sapienza Department of Physiology and Pharmacology Vittorio Erspamer, Roma, Italy
Maria Lucia Zaidan Dagli
University of Sao Paulo Faculty of Veterinary Medicine and Husbandry, Sao Paulo, Brazil
Barry Delclos
National Center for Toxicological Research, Jefferson, Arkansas, United States
Lennart Dencker
Uppsala University Faculty of Pharmacy, Uppsala, Sweden
Daniel R. Dietrich
University of Constance Human and Environmental Toxicology, Konstanz, Germany
José L. Domingo
School of Medicine, IISPV,Lab.Toxicology and Environmental Health,Universitat Rovira i Virgili, Reus, Catalonia, Spain
Nick Filipov
University of Georgia Department of Physiology and Pharmacology, Athens, Georgia, United States
Johannes G. Filser
Helmholtz Institute Munich Institute of Toxicology, Neuherberg, Germany
Ana-Maria Florea
Federal Institute for Risk Assessment, Berlin, Germany
Timothy Gant
King's College London Environmental Research Group Environmental Toxicology, London, United Kingdom
Ernie Harpur
Newcastle University Institute for Cell and Molecular Biosciences, Newcastle Upon Tyne, United Kingdom
Masayuki Ikeda
Kyoto Pharmaceutical Industries Ltd, Kyoto, Japan
Mumtaz Iscan
Ankara University Department of Oral and Maxillofacial Surgery, Ankara, Turkey
Dag Jenssen
Stockholms University Department of Genetics Microbiology and Toxicology, Stockholm, Sweden
Zhenquan Jia
University of North Carolina at Greensboro Department of Biology, Greensboro, North Carolina, United States
Lars-Oliver Klotz
Friedrich Schiller University Jena Institute of Nutrition, Jena, Germany
Jyrki Liesivuori
University of Turku Department of Pharmacology Drug development and Drug therapy, Turku, Finland
Dominique Lison
Catholic University of Louvain, Louvain-la-Neuve, Belgium
Bin Liu
University of Florida Department of Pharmacodynamics, Gainesville, Florida, United States
Francesco de Matteis
Medical Research Council
Hua Naranmandura
Zhejiang University School of Medicine, Hangzhou, China
Paolo Preziosi
Catholic University of the Sacred Heart Institute of Pharmacology, Rome, Italy
Xiaofa Qin
New Jersey Medical School Department of Medicine, Newark, New Jersey, United States
Jun Ren
University of Wyoming Family Medicine Residency Program - Cheyenne, Cheyenne, Wyoming, United States
Saura Sahu
Center for Food Safety and Applied Nutrition, College Park, Maryland, United States
Christie M. Sayes
RTI International, Research Triangle Park, North Carolina, United States
Seema Somji
University of North Dakota Department of Pathology, Grand Forks, North Dakota, United States
Helga Stopper
Julius Maximilians University Wurzburg Department of Toxicology, Wurzburg, Germany
Brian Thrall
Pacific Northwest National Laboratory, Richland, Washington, United States
Aristides Tsatsakis
University of Crete Laboratory of Toxicology and Forensic Chemistry, Irakleio, Greece
Juoko Tuomisto
National Institute for Health and Welfare Environmental Health Unit, KUOPIO, Finland
Eugenio G. Vilanova
Miguel Hernandez University of Elche Faculty of Experimental Sciences, Elx, Spain
Michael Wilhelm
Ruhr University Bochum Institute of Hygiene and Microbiology Department of Medical Microbiology, Bochum, Germany
Martin Wilks
Swiss Centre for Applied Human Toxicology, Basel, Switzerland
Marc Williams
Army Public Health Center, Aberdeen Proving Ground, Maryland, United States
Hao Yin
Massachusetts Institute of Technology Koch Institute for Integrative Cancer Research, Cambridge, Massachusetts, United States
Yunfeng Zhao
Louisiana State University Health Sciences Center Shreveport Department of Pharmacology Toxicology and Neuroscience, Shreveport, Louisiana, United States
Hong Zhu
Campbell University, Buies Creek, North Carolina, United States