Affiliated with the German Toxicology Society

Toxicology as a multidisciplinary, data-rich field has witnessed the availability of a cutting-edge technologies to investigate mechanisms underlying adverse consequences of exposures to xenobiotic chemicals, particularly as it relates to human health. Toxicology fully embraces these advancements by serving as a hub for exchange of information regarding state-of-the-art developments in the broad field of contemporary toxicology. Journal scope emphasis is on human-relevant and mechanistic research at all levels of biological organization, ranging from the molecular scale to the organismal level. The publication priority for Toxicology is on original high-quality research and review papers on any topic relevant to toxicology, in particular related to hazard identification, all that are subject to rigorous peer-review. The Toxicology target audience includes undergraduates to full professionals in academic, industrial and regulatory settings in any part of the world.

Notes from the Editors

In order to support interpretation of published findings to human health, the journal requires inclusion of specific statements within the ABSTRACT and METHODS sections of each submitted article:

ABSTRACT:
The experimental system (e.g., in vivo species, cell culture, etc.) including the exposure dose or concentration and duration that produces an effect, if an effect is observed, must be described in the ABSTRACT to the manuscript.
MATERIALS AND METHODS:
The relevance of the experimental system and exposure dose or concentration and duration in terms of potential human exposures must be described in the Materials and Methods section of the manuscript. Justification of the exposure cannot be based solely on previous publications, but rather the comparison must be to either estimated, anticipated, or measured human exposures.
The authors must identify the chemicals by CAS number, their source and purity; the method of randomization for group sampling, the number of experimental sample replicates in each treatment group, and provide a proper description of the statistical analysis of data that was employed.
Journal Policy:
TOXICOLOGY does not publish results from exposures to uncharacterized chemical mixtures or extracts from natural products. All exposures must be fully characterized analytically. Justification for this policy is that it is near impossible for other investigators to replicate findings of a study wherein the chemical composition of the exposure is not completely characterized.
TOXICOLOGY does not publish purely descriptive safety studies or studies describing the therapeutic efficacy of cytotoxic agents without strong emphasis on end-points relating to a proposed mechanism of toxicity.

original research articles
concise and current review
mini-review articles

Editor in Chief
Kendall B. Wallace
University of Minnesota Duluth Department of Biomedical Sciences, 345 School of Medicine - 1035 University Drive, Duluth, Minnesota, 55812-3031, United States, Fax: +1 218 726 8014 Phone +1 218 726 8899
Associate Editors
Emanuela Corsini
University of Milan Department of Environmental Science and Policy, Milano, Italy
Marion Ehrich, PhD, DABT
Virginia-Maryland Regional College of Veterinary Medicine, Blacksburg, Virginia, United States
Christopher Lau, PhD
US Environmental Protection Agency National Health and Environmental Effects Research Laboratory, Research Triangle Park, North Carolina, United States
Gary O. Rankin, PhD
Marshall University Department of Biomedical Sciences, Huntington, West Virginia, United States
Matthew Wright
Newcastle University Institute of Cellular Medicine, Newcastle Upon Tyne, United Kingdom
Editorial Board
Stelvio Bandiera
University of Guelph Department of Chemistry, Vancouver, British Columbia, Canada
Holger Barth
University Hospital Ulm Institute of Pharmacology and Toxicology, Ulm, Germany
Richard J. Bull
MoBull Consulting, Richland, Washington, United States
Jason R. Cannon, PhD
Purdue University School of Health Sciences, West Lafayette, Indiana, United States
Gary Carlson
Purdue University School of Health Sciences, West Lafayette, Indiana, United States
Omar Cauli
University of Valencia Department of Nursing, València, Spain
Janice Chambers
Mississippi State University College of Veterinary Medicine, Mississippi State, Mississippi, United States
Samuel M. Cohen
University of Nebraska Department of Pathology and Microbiology, Omaha, Nebraska, United States
Christopher Corton
Environmental Protection Agency Division of Integrated Systems Toxicology, Research Triangle Park, North Carolina, United States
Deborah A. Cory-Slechta, PhD
University of Rochester Medical Center Department of Medicine, Rochester, New York, United States
George Daston
Procter and Gamble Co, Cincinnati, Ohio, United States
Javier Del Pino, PharmaD, PhD
University of Madrid, Department of Pharmacology and Toxicology, Madrid, Spain
Jacques Descotes
Regional Centre for Pharmaceutical Surveillance Lyon, Lyon, France
José L. Domingo
School of Medicine, IISPV,Lab.Toxicology and Environmental Health,Universitat Rovira i Virgili, Reus, Catalonia, Spain
Janine Ezendam
National Institute of Public Health and the Environment, Bilthoven, Netherlands
John R. Foster, BSc, PhD, DipRCPath, FRCPath, FIATP, HonFBTS
Regulatory Science Associates Pathology Group, Congleton, United Kingdom
Patricia E. Ganey
Michigan State University Department of Pharmacology and Toxicology, East Lansing, Michigan, United States
Robert M. Gogal
The University of Georgia, Athens, Georgia, United States
Nigel J. Gooderham
Imperial College London Toxicology Unit, London, United Kingdom
Mary Gulumian
National Institute for Occupational Safety and Health, Washington, District of Columbia, United States
Stefan Hockertz
Toxicology Pharmacology Immunology Consulting, Bollschweil, Germany
Milan Jokanovic
Serbian Academy of Sciences and Arts, Beograd, Serbia
Norbert Kaminski
Michigan State University Department of Pharmacology and Toxicology, East Lansing, Michigan, United States
Wilma G. Kempinas, MS, PhD
São Paulo State University, Institute of Biosciences of Botucatu, Department of Morphology, Botucatu, São Paulo, Brazil
Elaina Kenyon
US Environmental Protection Agency National Health and Environmental Effects Research Laboratory, Research Triangle Park, North Carolina, United States
M. Firoze Khan
University of Texas Medical Branch Department of Pathology, Galveston, TX, United States
James Klaunig
Indiana University Department of Pharmacology and Toxicology, Indianapolis, Indiana, United States
B. Paige Lawrence
University of Rochester School of Medicine and Dentistry, Rochester, New York, United States
M.-C. Chang
Chang Gung University, Taoyuan, Taiwan
José E. Manautou, PhD
University of Connecticut Department of Pharmaceutical Sciences, Storrs, Connecticut, United States
Richard Manderville
University of Guelph, Guelph, Ontario, Canada
Francis L. Martin
Lancaster University Department of Biological Sciences, Lancaster, United Kingdom
David L. McCormick
IIT Research Institute, Chicago, Illinois, United States
Pasquale Mosesso
University of Tuscia Department of Biological and Ecological Sciences, Viterbo, Italy
David J. Nikolic-Paterson, D.Phil
Monash University Department of Medicine, Clayton, Victoria, Australia
Gunter Oberdörster
University of Rochester Medical Center Department of Environmental Medicine, Rochester, New York, United States
Elena A. Ostrakhovitch
Western University Department of Chemistry, London, Ontario, Canada
Markus Paulmichl
Paracelsus Medical Private University Institute of Pharmacology and Toxicology, Salzburg, Austria
Jurgen Pauluhn
Bayer HealthCare AG Pharma und Chemiepark Wuppertal, Wuppertal, Germany
Stephane Pillet
INRS-Institut Armand-Frappier, Laval, Quebec, Canada
Carey Nat Pope, PhD
Oklahoma State University Center for Veterinary Sciences, Stillwater, Oklahoma, United States
Elmar Richter
LMU Munich Walther Straub Institute of Pharmacology and Toxicology, München, Germany
Cynthia R. Rider
National Institutes of Health, Bethesda, Maryland, United States
Ivonne M.C.M. Rietjens
Wageningen University Sub-department of Toxicology, Wageningen, Netherlands
John Rogers
US Environmental Protection Agency National Health and Environmental Effects Research Laboratory, Research Triangle Park, North Carolina, United States
Kai Savolainen
Finnish Institute of Occupational Health, HELSINKI, Finland
Gilbert Schoenfelder
Charite University Hospital Berlin Institute of Clinical Pharmacology and Toxicology, Berlin, Germany
Dieter Schrenk
Technical University Kaiserslautern Food Chemistry and Toxicology, Kaiserslautern, Germany
William M. Valentine
Vanderbilt University Department of Pathology Microbiology and Immunology, Nashville, Tennessee, United States
David R. Wallace
Oklahoma State University Stillwater, Stillwater, Oklahoma, United States
Chiho Watanabe
The University of Tokyo Graduate School of Medicine Department of International Health Human Ecology, Bunkyo-Ku, Japan
Calvin C. Willhite
Risk Sciences International, Ottawa, Ontario, Canada
Honorary Editors
Hans Marquardt
Hamburg University Medical School Department of Toxicology, Kortenredder 3, 22397, Hamburg, Germany, Fax: +49 40 60558553 Phone +49 40 6050748
Karl Netter
University of Marburg Institute of Pharmacology and Clinical Pharmacy, Karl-von-Frisch-Strasse 1, D-35033, Marburg, Germany, Fax: +49 6421 2865600
Hans-Peter Witschi
University of California Davis Center for Health and the Environment, Old Davis Road, Building 3792, Room 129, Davis, California, CA 95616-8615, United States, Fax: +1 530 752 5300