Clinical Chemistry, a journal of the Association for Diagnostics & Laboratory Medicine (ADLM), is the premier journal of the science and practice of clinical laboratory medicine. Since its establishment in 1955, this peer-reviewed scientific journal has been a focal point for publications relevant to the laboratory diagnosis and management of patients. Over its history, the journal has become relevant not only to clinical chemistry, but other clinical laboratory disciplines including genomics, hematology, microbiology, and toxicology. The journal routinely publishes articles of interest to clinical specialties such as cardiology, endocrinology, gastroenterology, genetics, immunology, infectious diseases, maternal-fetal medicine, neurology, nutrition, oncology, and pediatrics.

In addition to original research, editorials, and reviews, Clinical Chemistry has several recurring features such as clinical case studies, perspectives, podcasts, and Q&A articles.

Clinical Chemistry currently has the highest impact factor among journals of clinical chemistry, laboratory medicine, pathology, analytical chemistry, transfusion medicine and clinical microbiology. The journal is indexed in databases such as MEDLINE and Web of Science.

The journal’s impact factor was 9.3 in the 2023 Clarivate Journal Citation Reports.

The journal strives for timely evaluation of submitted manuscripts. For 2022, original research articles had a median time from submission to first editor decision of 1.5 days. Articles had a median time from submission to a final decision of acceptance of 93.4 days. For a final decision of rejection, the median time from submission was 12.0 days. The median time from submission to online publication was 138.4 days.

Editor-in-Chief
Nader Rifai
Boston Children's Hospital, Harvard Medical School, Boston, MA
Deputy Editors
Thomas Michael Annesley
University of Michigan, Ann Arbor, MI
James C. Boyd
University of Virginia, Charlottesville, VA
Associate Editors
Fred S. Apple 
Hennepin County Medical Center, University of Minnesota, Minneapolis, MN
Linnea M. Bauduin
Perspectives Editor
Mayo Clinic, Rochester, MN
Michael J. Bennett
University of Pennsylvania, Philadelphia, PA
Rossa Wai Kwun Chiu
Q&A Editor
The Chinese University of Hong Kong, China
Christina Ellervik
Adaptive Learning Initiative Co-Editor
Boston Children's Hospital, Harvard Medical School, Boston, MA
Paolo Fortina
Thomas Jefferson University, Philadelphia, PA
Ann Gronowski
Clinical Case Studies Co-Editor
Clinical Chemistry Trainee Council Co-Chair
Washington University, School of Medicine, St. Louis, MO
Shannon Haymond
Social Media Editor 
Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL
Andrew Norbert Hoofnagle
University of Washington, Seattle, Washington
Gary L. Horowitz
Clinical Case Studies Co-Editor
Tufts Medical Center, Boston, MA
Yuk-Ming Dennis Lo
The Chinese University of Hong Kong, Hong Kong, China
Greg Miller
Virginia Commonwealth University, Richmond, VA
Jason Y. Park
Reviews Co-Editor
University of Texas Southwestern Medical Center, Dallas, TX
Robert Rej
New Media Editor
Wadsworth Center for Laboratories and Research, Albany, NY
David Barry Sacks
National Institutes of Health, Bethesda, MD
Mitchell George Scott
Washington University, School of Medicine, St. Louis, MO
Ping Wang
Reviews Co-Editor
University of Pennsylvania, Philadelphia, PA
Carl T. Wittwer
University of Utah, Salt Lake City, UT
Ian S. Young
Royal Group of Hospitals, Belfast, Northern Ireland
Board Members
Patrick M.M. Bossuyt
Academic Medical Center, University of Amsterdam, The Netherlands
Carey-Ann Burnham
Washington University, School of Medicine, St. Louis, MO
Stephen A. Bustin
Anglia Ruskin University, Chelmsford, United Kingdom
Steven A. Carr
Broad Institute, Harvard University/MIT, Cambridge, MA
Nancy R. Cook
Brigham and Women's Hospital, Harvard Medical School, Boston, MA
Graham Cooks
Purdue University, West Lafayette, IN
Mari L. DeMarco
University of British Columbia, Providence Health Care, Vancouver, Canada
Charles S. Eby
Washington University School of Medicine, St. Louis, MO
Graeme Eisenhofer
Dresden Technical University Medical Center, Germany
Frank B. Hu
Harvard School of Public Health, Boston, MA
John P.A. Ioannidis
Stanford University, Stanford, CA
David R. Jacobs
University of Minnesota, Minneapolis, MN
Allan S. Jaffe
Mayo Clinic, Rochester, MN
Peter Kavasak
McMaster University, Hamilton, Ontario, Canada
Kathleen F. Kerr
University of Washington, Seattle, WA
Wolfgang Koenig
University of Ulm Medical Center, Germany
Larry J. Kricka
University of Pennsylvania, Philadelphia, PA
Kristian Linnet
University of Copenhagen, Denmark
Kara Lynch
University of California San Francisco, San Francisco, CA
G. Mike Makrigiorgos
Dana Farber Cancer Institute, Harvard Medical School, Boston, MA
JoAnn Manson
Brigham and Women's Hospital, Harvard Medical School, Boston, MA
Elaine Mardis
Institute for Genomic Medicine, The Ohio State University, Columbus, OH
Stephen R. Master
Children's Hospital of Philadelphia, Philadelphia, PA
David A. Marrow
Brigham and Women's Hospital, Harvard Medical School, Boston, MA
Borge G. Nordestgaard
Herlev Hospital, University of Copenhagen, Copenhagen, Denmark
Klaus Pantel
University Medical Center Hamburg-Eppendorf, Germany
Alan Thomas Ramaley
National Institutes of Health, Bethesda, MD
Ulf-Hkan Stenman
Helsinki University Central Hospital, Finland
Dorine W. Swinkels
Radboudumc, The Netherlands
Gregory J. Tsongalis
Dartmouth-Hitchcock Medical Center, Lebanon, NH
Jennifer E. Van Eyk
Cedars-Sinai Medical Center, Los Angeles, CA
Kenneth W Witwer
The Johns Hopkins University School of Medicine, Baltimore, MD
SYCL Liaison
Joe M. El-Khoury
Yale University, Newhaven, CT