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Editor Alison Cuff, BioMed Central, Germany Manuscript Editor Doris Cuckovic, BioMed Central, UK Assistant Editor Danielle Talbot, BioMed Central, UK Section Editors Knowledge-based analysis Karin Verspoor University of Melbourne, Australia Machine Learning and Artificial Intelligence in Bioinformatics Jean-Philippe Vert, Ecole des Mines de Paris, France Sequence analysis Joao C Setubal, Universidade de Sao Paulo, Brazil Jens Stoye, Universität Bielefeld, Germany Structural analysis Lukasz Kurgan, Virginia Commonwealth University, USA Data Visualization Andrew Cohen, Drexel University, USA Shuiwang Ji, Texas A&M University, USA
Associate Editors Analysis and modelling of complex systems Julio Banga, Spanish National Research Council (CSIC), Spain Pablo Carbonell, Manchester Institute of Biotechnology, UK Chiara Damiani, University of Milano-Bicocca, Italy Johann Rohwer, Stellenbosch University, South Africa Edwin Wang, University of Calgary, Canada Zhihui Wang, Houston Methodist Research Institute, USA Comparative genomics Marcella Attimonelli, University of Bari, Italy Nadia El-Mabrouk, University of Montreal, Canada Guillaume Fertin, Universite de Nantes, France J Peter Gogarten, University of Connecticut, USA David Horner, University of Milan, Italy Shailesh Kumar, National Institute of Plant Genome Research (NIPGR), India Petro Lio, University of Cambridge, UK Wojciech Makalowski, University of Muenster, Germany Enno Ohlebusch, University of Ulm, Germany Laxmi Parida, IBM T J Watson research Center, USA Guy Perriere, Universite Claude Bernard, France David Sankoff, University of Ottawa, Canada Gabriel Valiente, Technical University of Catalonia, Spain Rafael Zardoya, Museo Nacional de Ciencias Naturales, Spain Liqing Zhang, Virginia Tech, USA Yang Zhong, Fudan University, China Imaging, image analysis and data visualization Andrew Cohen, Drexel University, USA Nils Gehlenborg, Harvard Medical School, USA Shuiwang Ji, Washington State University, USA Hwee Kuan Hwee Lee, Bioinformatics Institute, Singapore Fuhui Long, HHMI, USA B. S. Manjunath, University of California, Santa Barbara, USA Arrate Munoz-Barrutia, University Carlos III of Madrid, Spain Jean-Christophe Olivo-Marin, Institut Pasteur, France Gustavo Rohde, Carnegie Mellon University, USA Ivo Sbalzarini, MPI of Molecular Cell Biology and Genetics, Germany Pavel Tomancak, MPI-CBG, Germany Ge Yan, Carnegie Mellon University, USA Lin Yang, University of Florida, USA Guoqiang Yu, Virginia Tech, USA Knowledge-based analysis Christopher Baker, University of New Brunswick, Canada Judith A Blake, The Jackson Laboratory, USA Claudine Chaouiya, Instituto Gulbenkian de Ciencia, Portugal Kevin Cohen, University of Colorado, USA Trevor Cohen, University of Washington, USA Nigel Collier, University of Cambridge, UK Rezarta Islamaj Dogan, National Center for Biotechnology Information, USA Lawrence Hunter, University of Colorado, USA Phil Lee, Massachusetts General Hospital, USA Ulf Leser, Humboldt Universität, Germany Zhiyong Lu, NCBI, USA Bridget McInnes, Virginia Commonwealth University, USA Aurelie Neveol, CNRS, France Philippe Rocca-Serra, University of Oxford, UK Luis Rocha, Indiana University, USA Paolo Romano, Instituto Nazionale per la Ricerca sul Cancro, Italy Patrick Ruch, Swiss Institute of Bioinformatics, Switzerland Padmini Srinivasan, University of Iowa, USA Karin Verspoor, National ICT Australia, Australia Mohammed Yeasin, University of Memphis, USA Machine learning and artificial intelligence Vladimir Brusic, University of Nottingham Ningbo China, China Xin Gao, King Abdullah University of Science and Technology (KAUST), Saudi Arabia Jianjun Hu, University of South Carolina, USA Alexandros Iosifidis, Aarhus University, Denmark Haiquan Li, University of Arizona, USA Yifeng Li, National Research Council of Canada, Canada Pier Luigi Martelli, University of Bologna, Italy George Spyrou, The Cyprus Institute of Neurology and Genetics, Cyprus William Stafford Noble, University of Washington, USA Catia Pesquita, Faculdade de Ciências da Universidade de Lisboa, Portugal Dick de Ridder, Wageningen University and Research, Netherlands Simon Rogers, University of Glasgow, UK Juho Rousu, Aalto University, Finland Roberto Tagliaferri, University of Salerno, Italy Jean-Philippe Vert, Ecole des Mines de Paris, France Qi Zhang, University of Nebraska Lincoln, USA Degui Zhu, University of Texas, USA Networks analysis Jake Chen, The University of Alabama at Birmingham, USA Xing Chen, China University of Mining and Technology, China Thomas Dandekar, University of Wuerzburg, Germany Jean-Jacques Daudin, AgroParisTech, France Eytan Domany, Weizmann Institute of Science, Israel Arne Elofsson, Stockholm University, Sweden Hsien-Da Huang, National Chiao Tung University, Taiwan Curtis Huttenhower, Harvard School of Public Health, USA Ina Koch, Goethe-University Frankfurt, Germany Yves Lussier, University of Illinois in Chicago, USA Hiroshi Mamitsuka, Kyoto University, Japan Kathleen Marchal, K.U.Leuven, Belgium Parvin Mousavi, Queen's University, Canada Christine Nardini, Key Laboratory of Computational Biology, MPG-CAS PICB, Shanghai, China Michael Ochs, John Hopkins University, USA Florencio Pazos, National Centre for Biotechnology, Spain Anton Peeters, Utrecht University, Netherlands Natasa Przulj, Imperial College London, UK Teresa M Przytycka, NLM / NIH, USA Jaques Reifman, US Army Medical Research and Materiel Command, USA Andre Ribeiro, Tampere University of Technology, Finland Marie France Sagot, Université Claude Bernard, France Roded Sharan, Tel Aviv University, Israel Mona Singh, Princeton University, USA Ulrich Stelzl, Max-Planck-Institute for Molecular Genetics, Germany Michael Stumpf, Imperial College London, UK Fabio Vandin, University of Padova, Italy Stefan Wuchty, National Institutes of Health, USA Byung-Jun Yoon, Texas A&M University, USA Erliang Zeng, University of South Dakota, USA Novel computational methods for the analysis of biological systems James Collins, Massachusetts Institute of Technology, USA Frank Emmert-Streib, Tampere University, Finland Feng Luo, Clemson University, USA Qing Nie, University of California, USA Irene Otero-Muras, CSIC (Spanish National Research Council), Spain Proteomics Nuno Bandeira, University of California, San Diego, USA Zhuchu Chen, Xiang-Ya Hospital, Central South University, China Timothy Ebbels, Imperial College London, UK Frank Eisenhaber, Bioinformatics Institute, Singapore Artemis G Hatzigeorgiou, Alexander Fleming Biomedical Sciences Research Center, Greece Steffen Neumann, IPB Halle, Germany Magnus Palmblad, Leiden University Medical Center, Netherlands Juri Rappsilber, University of Edinburgh, UK Victor Segura, CIMA Universidad de Navarra, Spain Peter F Stadler, University Leipzig / Max-Planck-Institute, Germany Sequence analysis (applications) Benjamin Audit, Ecole Normale Supérieure de Lyon, France Emmanuel Barillot, Institut Curie, France Mathieu Blanchette, McGill University, Canada Ramon Diaz-Uriarte, Spanish National Cancer Centre (CNIO), Spain Frank Dudbridge, London School of Hygiene and Tropical Medicine, UK Mathieu Fourment, University of Technology Sydney, Australia Daniel Gautheret, Université Paris Sud, France Derek Gordon, Rutgers State University, USA Saman Halgamuge, University of Melbourne, Australia Eivind Hovig, The Norwegian Radium Hospital, Norway Jose MG Izarzugaza, Technical University of Denmark, Denmark Xiaoqiu Huang, Iowa State University, USA Xiaole Liu, Dana-Farber Cancer Institute, USA Folker Meyer, Argonne National Laboratory, USA Colm Tadhg O'Dushlaine, Broad Institute of MIT and Harvard, USA Ivan Ovcharenko, National Center for Biotechnology Information (NCBI), USA Francesco Papparlardo, University of Catania, Italy Miguel Perez-Enciso, Universitat Autònoma Barcelona, Spain Ping Qiu, Schering-Plough Research Institute, USA Gajendra Raghava, Institute of Microbial Technology, India Eric Rivals, LIRMM, CNRS & Univ. Montpellier II, France David M Rocke, University of California, Davis, USA Christian Schlötterer, Vetmeduni Vienna, Austria Alexander Sczyrba, Bielefeld University, Germany Denis Shields, University College Dublin, Ireland Andrew Skol, University of Chicago, USA Jens Stoye, Universitat Bielefeld, Germany Jijun Tang, University of South Carolina, USA Todd J Treangen, National Biodefense Analysis and Countermeasures Center, USA Susana Vinga, IDMEC/IST-UL, Portugal Lusheng Wang, City University of Hong Kong, China Zhiping Weng, Boston University, USA Zheng Rong Yang, University of Exeter, UK Michael Zhang, Cold Spring Harbor Lab, USA Xuegong Zhang, Tsinghua University, China Sequence analysis (methods) Can Alkan, Bilkent University, Turkey Anne Bergeron, Université du Québec à Montréal, Canada Dominik Heider, Straubing Center of Science, Germany Minlie Huang, Tsinghua University, China Kazutaka Katoh, National Institute of Advanced Industrial Science and Technology, Japan Uri Keich, University of Sydney, Australia Anders Krogh, University of Copenhagen, Denmark Thomas Lingner, University of Goettingen, Germany Ion Mandoiu, University of Connecticut, USA Alexander Schliep, Rutgers State University, USA Christine Sinoquet, University of Nantes, France Haixu Tang, Indiana University, USA Julie Thompson, ICube, France Zhi Wei, New Jersey Institute of Technology, USA Xiaohui Xie, University of California, Irvine, USA Weichuan Yu, Hong Kong University of Science and Technology, Hong Kong Jianwei Zhang, The University of Arizona, USA Structural analysis Tatsuya Akutsu, Kyoto University, Japan Chris Bailey-Kellogg, Dartmouth College, USA Khaled H Barakat, University of Alberta, Canada Richard Bonneau, New York University, USA Michal Brylinski, Louisiana State University, USA Zhiwei Cao, Tongji University, China Rita Casadio, University of Bologna, Italy Piotr Cieplak, Sanford-Burnham Medical Research Institute, USA Stanisław Dunin-Horkawicz, University of Warsaw, Poland Iddo Friedberg, Miami University of Ohio, USA Michael Gromiha, Computational Biology Research Center, India Dukka KC, North Carolina A&T State University, USA Daisuke Kihara, Purdue University, USA Pandjassarame Kangueane, Biomedical Informatics, India Luhua Lai, Peking University, China Jinyan Li, University of Technology Sydney, Australia Alberto Jesus Martin, Universidad Mayor, Chile Pedro Serrano Navarro, Joint Center for Structural Genomics, The Scripps, USA Jean-Christophe Nebel, Kingston University, UK Ruth Nussinov, National Cancer Institute, USA Baldo Oliva, Universitat Pompeu Fabra, Spain Dariusz Plewczynski, University of Warsaw, Poland Rituraj Purohit, Institute of Himalayan Bioresource Technology, India Shoba Ranganathan, Macquarie University, Australia Hong-Bin Shen, Shanghai Jiaotong University, USA Ian Sillitoe, University College London, UK Jiangning Song, Monash University, Australia Sri Krishna Subramanian, Institute of Microbial Technology, India Shoshana Wodak, University of Toronto, Canada Lei Xie, The City University of New York, USA Bin Xue, University of South Florida, USA Jianyi Yang, Nankai University, China Yuedong Yang, Griffith University, Australia Yuzhen Ye, Indiana University, USA Transcriptome analysis Constantin F. Aliferis, Vanderbilt University, USA Nuno L Barbosa-Morais, Instituto de Medicina Molecular, Portugal Tim Beissbarth, University Medicine Göttingen, Germany Riccardo Bellazzi, Università degli Studi di Pavia, Italy Daniel Berrar, University of Ulster, UK Benedikt Brors, German Cancer Research Center, Germany Raffaele Calogero, University of Torino, Italy Vincent Carey, Harvard Medical School, USA David Casero, University of California Los Angeles (UCLA), USA Duccio Cavalieri, University of Florence, Italy Somnath Datta, University of Louisville, USA Sean R. Davis, NIH, USA Lana Garmire, University of Hawaii, USA Raffaele Giancarlo, Università di Palermo, Italy Ze-Guang Han, Chinese National Human Genome Center, China Andrew Harrison, University of Essex, UK Sunduz Keles, University of Wisconsin, Madison, USA Katerina Kechris, University of Colorado, Denver, USA Anil Kesarwani, The Jackson Laboratory, USA Arkady Khodursky, University of Minnesota, USA Rahul Kumar, Institute of Cancer Research, UK Peng Liu, Iowa State University, USA Geoff McLachlan, University of Queensland, Australia Sumit Middha, MSKCC, USA Qianxing Mo, Baylor College of Medicine, USA Ali J Mortazavi, California Institute of Technology, USA Vasu Punj, USC, USA Rommel Thiago Juca Ramos, Universidade Federal do Pará, Brazil Kristin Reiche, Fraunhofer Institute for Cell Therapy and Immunology, Germany Chiara Romualdi, CRIBI Biotechnology Center, Italy Chiara Sabatti, Stanford University, USA Mark R Segal, University of California, San Francisco, USA Chen-An Tsai, China Medical University, Taiwan Mark P Wachowiak, Nipissing University, Canada Liguo Wang, Mayo Clinic, USA Jean Yang, University of Sydney, Australia Peng Yu, Texas A&M University, USA Zhaojie Zhang, St Jude Children's Research Hospital, USA Fatima Al-Shahrour, Spanish National Cancer Research Centre, Spain Editorial Advisors Michael R Brent, Washington University in St. Louis, USA Janusz Bujnicki, International Institute of Molecular and Cell Biology in Warsaw, Poland Matthew J Chalmers, University of Glasgow, UK Ting Chen, University of Southern California, USA Kevin R Coombes, University of Texas M.D. Anderson Cancer Center, USA Richard Copley, Wellcome Trust Centre For Human Genetics, UK Sandrine Dudoit, University of California, Berkeley, USA Janan T Eppig, The Jackson Laboratory, USA Olivier Gascuel, LIRMM-CNRS, France Mikhail Gelfand, Russian Academy of Science, Russian Federation Mark Gerstein, Yale University, USA Winston Hide, Harvard School of Public Health, USA Des G Higgins, The Conway Institute, Ireland Lawrence Hunter, University of Colorado, USA Rafael Irizarry, Johns Hopkins Bloomberg School of Public Health, USA Tao Jiang, University of California, Riverside, USA Peter D Karp, SRI International, USA Steen Knudsen, Medical Prognosis Insititute, Denmark Deepak Kumar, University of the District of Columbia, USA Jonathan Pevsner, Kennedy Krieger Institute, USA J Sunil Rao, School of Medicine, University of Miami, USA J Sunil Rao, Case Western Reserve University, USA Steven Salzberg, Johns Hopkins University, USA Colin Semple, Western General Hospital, UK Donna Slonim, Tufts University, USA Gordon Smyth, Walter and Eliza Hall Institute of Medical Research, Australia Berend Snel, Utrecht University, Netherlands Tin Wee Tan, National University of Singapore, Singapore Masaru Tomita, Keio University, Japan Michael S Waterman, University of Southern California, USA Xiaoyan Zhu, Tsinghua University, China
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