Each topic-based issue of Best Practice & Research Clinical Gastroenterology will provide a comprehensive review of current clinical practice and thinking within the specialty of gastroenterology.

All chapters are commissioned and written by an international team of practising clinicians with the Guest Editors for each issue drawn from a pool of renowned experts and opinion leaders. Reference is made to:

• The latest original research
• Cochrane Reviews
• Audits and confidential enquiries
• National and international conferences
• National and international guidelines
• Personal communications

All chapters take the form of practical, evidence-based reviews that seek to address key clinical issues of diagnosis, treatment and patient management.

Each issue follows a problem-orientated approach that focuses on the key questions to be addressed, clearly defining what is known and not known. Management will be described in practical terms so that it can be applied to the individual patient.

Boxed and bulleted Learning Objectives and Practice Points are features within each chapter and will highlight the core and essential knowledge that will help the physician to provide the best care to their patients.

The series' objective is to provide a continuous update for the busy clinician and researcher.

Co Editors-in-Chief
Ernst Kuipers
Rotterdam, Netherlands Email Ernst Kuipers
Manon Spaander
Rotterdam, Netherlands Email Manon Spaander
Editorial Board
Jan Bornschein
Oxford, United Kingdom
Chyke A. Doubeni, MD, MPH
Rochester, Minnesota, United States
Cesare Hassan, PhD
Roma, Italy
Vasily Isakov
Moscow, Russian Federation
Michal F. Kaminski, MD, PhD
Warszawa, Poland
Zeynel Mungan
?stanbul, Turkey
James Neuberger
Birmingham, United Kingdom
Helmut Neumann, MD
Mainz, Germany
Roos E. Pouw, MD, PhD
Amsterdam, Netherlands