The Memórias' content is freely accessible to readers and no publication fees are charged to authors. The Memórias do Instituto Oswaldo Cruz has decided to simplify the requirements regarding the format of submitted manuscripts. From now on, all manuscripts  may be submitted in any text format as long as the common subdivision of scientific articles are followed, e.g. introduction, materials and methods, results, discussion and references. For Reviews, Perspectives and similar  articles, authors may use the sections that best suit the structure and content of the proposed manuscript. All manuscripts should  contain, besides the title and abstract, full details of authors and institutions, acknowledgements of any technical or financial assistance and authors must disclose any conflict of interest related to their research work. This flexible text format will be used for the initial analysis and peer review. the manuscript is accepted, authors will be requested to edit the text in accordance with the publication style of the Memorias.