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Editor-in-Chief Dr. Ronald T. Borchardt Department of Pharmaceutical Chemistry The University of Kansas 2095 Constant Ave., Room 121c Lawrence, Kansas 66047 Tel: (785) 864-5919 Fax: (785) 864-5875 E-mail: rborchardt@ku.edu or tdunning@ku.edu Emeritus Editor
William Higuchi University of Utah Salt Lake City, UT E-mail: whiguchi@pharm.utah.edu Editors
Bradley D. Anderson University of Kentucky Lexington, KY E-mail: bande2@email.uky.edu Kenneth L. Audus
The University of Kansas Lawrence, KS E-mail: audus@ku.edu Harry G. Brittain
Center for Pharmaceutical Physics Milford, NJ E-mail: hbrittain@centerpharmphysics.com
Ferdinando Giordano Torre d'Isola (Pavia), Italy E-mail: ferdinando.giordano@unipr.it
Michael J. Hageman Bristol-Myers Squibb Co. Princeton, NJ E-mail: michael.hageman@bms.com
Bruno C. Hancock Pfizer, Inc. Groton, CT E-mail: bruno.c.hancock@pfizer.com
Rodney Ho University of Washington Seattle, WA E-mail: rodneyho@uw.edu
C. Russell Middaugh The Universityof Kansas Lawrence, KS E-mail: middaugh@ku.edu
Thomas Rades Copenhagen University København, Denmark E-mail: thomas.rades@sund.ku.dk
Tetsuya Terasaki Tohoku University Sendai, Japan E-mail: terasaki.tetsuya@m.tohoku.ac.jp
Ijeoma F. Uchegbu University of London London, UK E-mail: Ijeoma.uchebgu@pharmacy.ac.uk
Editor of Reviews, Minireviews, General Commentaries, and Special Topic Commentaries John Carpenter University of Colorado Denver Denver, CO E-mail: john.carpenter@ucdenver.edu
Editor of Commentaries on Clinical Trials and Translational Medicine and Global Health Rodney Ho University of Washington Seattle, WA E-mail: rodneyho@u.washington.edu
Editorial Advisory Board Hua Ai Sichuan University Chengdu, P.R. China
Michael J. Akers Akers Consulting Martinsville, IN
Hidetaka Akita Hokkaido University Sapporo City, Japan
Carmen Alvarez-Lorenzo Universidad de Santiago de Compostela Santiago de Compostela, Spain
Gregory E. Amidon University of Michigan Ann Arbor, MI
Thomas J. Anchordoquy Univ. of Colorado Denver Denver, CO
Gavin P. Andrews Queens University Belfast Belfast, Ireland
Per Artursson Uppsala University Uppsala, Sweden
Patrick Augustijns Katholieke Universiteit Leuven Leuven, Belgium
Bruce J. Aungst QPS, LLC Newark, DE
Annette Bak Merck & Co. Rahway, NJ
Joseph Balthasar SUNY - University at Buffalo Buffalo, NY
Sathy V. Balu-Iyer SUNY - University of Buffalo Amherst, NY
James G. Bann Wichita State University Wichita, KS
Jared S. Bee Medlmmune Gaithersburg, MD
Cory Berkland The University of Kansas Lawrence, KS
Joel Bernstein New York University Abu Dhabi Abu Dhabi, United Arab Emirates
Michael Blaber Florida State University Tallahassee, FL
Robin H. Bogner University of Connecticut Storrs, CT
Kathleen MK Boje State University of Buffalo Amherst, NY
Ben J. Boyd Monash University Parkville, Australia
Birger Brodin University of Copenhagen Copenhagen, Denmark
Kenneth R. Brouwer Qualyst Transporter Solutions Durham, NC
James Butler GlaxoSmithKline Research & Development Essex, UK
Stephen R. Byrn Purdue University West Lafayette, IN
Mino R. Caira University of Capetown Rondebosch, South Africa
Carla M. Caramella University of Pavia Pavia, Italy
Adeola O. Coker University of the Incarnate Word San Antonio, TX
Duncan Q.M Craig UCL School of Pharmacy London, UK
John H. Crowe University of California, Davis Davis, CA
Richard T. Darrington Takeda Pharmaceuticals Intl. Co. Cambridge, MA
Martyn C. Davies University of Nottingham Nottingham, UK
Henk J. de Jong Leiden University/FIP Puteaux, France
Sven Deferme PharmaXL Boutersem Belgium
Yoshiharu Deguchi Teikyo University Kanagawa, Japan
Hartmut Derendorf University of Florida Gainesville, FL
Prashant Desai Eli Lilly and Company Indianapolis, IN
Jennifer Dressman Goethe University Frankfurt, Germany
Dave Elder GlaxoSmithKline Ware United Kingdom
Robert K. Evans Merck Research Laboratories West Point, PA
Elias Fattal University of Paris-Sud Châtenay-Malabry, France
Barrie C. Finnin Monash University Parkville, Australia
Mark T. Fisher University of Kansas Medical Center Kansas City, KS
Yatin R. Gokarn Gilead Sciences, Inc. Oceanside, CA
Igor Gonda Aradigm Corporation Hayward, CA
Kosalaram Goteti Medlmmune Gaithersburg, MD
Henrik Gréen Linköping Universitët Linköping, Sweden
Kai Griebenow University of Puerto Rico, Rio Piedras Campus San Juan, Puerto Rico
Richard H. Guy University of Bath Bath, UK
Jonathan Hadgraft University of London London, UK
Margareta Hammarlund-Udenaes Uppsala University Uppsala, Sweden
David J. Hauss Hauss Associates New York, NY
Anthony J. Hickey RTI International Research Triangle Park, NC
Ken-ichi Hosoya University of Toyama Toyama, Japan
Munir Hussain Bristol-Myers Squibb Company New Brunswick, NJ
Tatsuhiro Ishida The University of Tokushima Tokushima, Japan
Ken-ichi Izutsu National Institute of Health Sciences Tokyo, Japan
Wim Jiskoot Leiden University The Netherlands
Kevin C. Johnson Intellipharm, LLC Niantic, CT
David S. Jones Queen's University of Belfast Northern Ireland, UK
LaToya Jones-Braun Regis University Denver, CO
Devendra S. Kalonia University of Connecticut Storrs, CT
Gerald B. Kasting University of Cincinnati Cincinnati, OH
Yukio Kato Kanazawa University Kanazawa, Japan
Bruce A. Kerwin Just Seattle, WA
Filippos Kesisoglou Merck & Co., Inc. West Point, PA
Vitaliy Khutoryanskiy University of Reading Reading, UK
Peter Kleinebudde Heinrich-Heine-University Duesseldorf, Germany
Gregory T. Knipp Purdue University West Lafayette, IN
Janet Koe JGIJ Consulting LLC San Mateo, CA
Hiroyuki Kusuhara The University of Tokyo Tokyo, Japan
William J. Lambert Omeros Corporation Seattle, WA
Majella E. Lane UCL School of Pharmacy London, UK
Robert S. Langer Massachusetts Institute of Technology Cambridge, MA
Jennifer S. Laurence The University of Kansas Lawrence, KS
David Lechuga-Ballesteros Pearl Therapeutics, Inc. Redwood City, CA
Jean-Christophe Leroux Institute of Pharmaceutical Sciences ETH Zürich, Switzerland
Thorsteinn Loftsson Univeristy of Iceland Reykjavik, Iceland
Henry K. Mach Merck Research Laboratories West Point, PA
Hanns-Christian Mahler F. Hoffmann-La Roche Ltd. Basel, Switzerland
Amedeo Marini CSGI - University of Pavia Pavia, Italy
Toru Maruyama Kumamoto University Kumamoto, Japan
Brian E. Mattioni Merch Research Laboratories West Point, PA
Michael B. Maurin Maurin Healthcare Consulting Wilmington, DE
Mark McAllister Pfizer Kent, UK
Gary McGeorge Bristol-Myers Squibb New Brunswick, NJ
Patrick McNamara University of Kentucky Lexington, KY
Natalie Medlicott University of Otago Dunedin, New Zealand
Jan P. Moeschwitzer Next Pharma Berlin, Germany
Marilyn E. Morris University at Buffalo Amherst, NY
Anette Müllertz University of Copenhagen Copenhagen, Denmark
Eric Munson University of Kentucky Lexington, KY
S. Narasimha Murthy The University of Mississippi University, MS
Steven Nail Baxter Medical Products R & D Bloomington, IN
Miki Nakajima Kanazawa University Kanazawa, Japan
Ashwini Nangia University of Hyderabad Hyderabad, India
Linda Owers Narhi Amgen, Inc. Thousand Oaks, CA
Marino Nebuloni REDOX and Parma University Parma, Italy
Thanh Nguyen University College London London, UK
Joseph A. Nicolazzo Monash University Parkville, Australia
Hanne Mørck Nielsen University of Copenhagen Copenhagen, Denmark
Takuo Ogihara Takasaki University of Health & Welfare Gunma, Japan
Sumio Ohtsuki Kumamoto University Kumamoto, Japan
Tetsuya Ozeki Nagoya City University Nagoya, Japan
Jayanth Panyam University of Minnesota Minneapolis, MN
Yvonne Perrie Aston University Birmingham, UK
Michael J. Pikal University of Connecticut Storrs, CT
James E. Polli University of Maryland Baltimore, MD
Christopher J. H. Porter Monash University Melbourne, Australia
Richard J. Prankerd Monash University Parkville, Australia
Theodore W. Randolph University of Colorado Boulder, CO
Jukka Rantanen University of Copenhagen Copenhagen, Denmark
Susan Reutzel-Edens Eli Lilly & Company Indianapolis, IN
Kevin G. Rice University of Iowa Iowa City, IA
Naír Rodríguez-Hornedo The University of Michigan Ann Arbor, MI
Mark C. Rogge Biogen Idec, Inc. Cambridge, MA
Amy Rosenberg Division of Therapeutic Proteins, CDER, FDA Bethesda, MD
Chandrahas Sahajwalla Silver Spring, MD
Yoshimichi Sai Kanazawa University Hospital Kanazawa, Japan
Krishnan Sampath Hospira Inc. Lake Forest, IL
Niklas Sandler Abo Akademi University Turku, Finland
Hitoshi Sasaki Nagasaki University Hospital Nagasaki, Japan
Christian Schöneich The University of Kansas Lawrence, KS
Abu T. M. Serajuddin St. John's University Queens, NY
Danny D. Shen University of Washington Seattle, WA
Teruna J. Siahaan The University of Kansas Lawrence, KS
Satish K. Singh Pfizer, Inc. Chesterfield, MO
Pierre Souillac Shire Lexington, MA
David Spencer Med Immune, Inc. Gaithersburg, MD
Valentino J. Stella The University of Kansas Lawrence, KS
Gregory A. Stephenson Eli Lilly and Company Indianapolis, IN
Audra Stinchcomb University of Kentucky and AllTranz Inc. Lexington, KY
Robert M. Straubinger University at Buffalo Buffalo, NY
Robert Strickley Gilead Sciences, Inc. Foster City, CA
Changquan Calvin Sun University of Minnesota Minneapolis, MN
Raj G. Suryanarayanan University of Minnesota Minneapolis, MN
Masanori Tachikawa Tohoku University Sendai, Japan
David R. Taft Long Island University Brooklyn, NY
Mikihisa Takano Hiroshima University Hiroshima, Japan
Yun K. Tam Sinoveda Canada Inc. Edmonton, Alberta, Canada
Ikumi Tamai Kanazawa University Kanazawa, Japan
Lynne S. Taylor Purdue University West Lafayette, IN
Allen C. Templeton Merck Research Laboratories West Point, PA
Dhiren R. Thakker The University of North Carolina Chapel Hill, NC
Frank-Peter Theil UCB Pharma Brussels, Belgium
Mike Tobyn Bristol-Myers Squibb Moreton, UK
Masatoshi Tomi Keio University Tokyo, Japan
Vladimir Torchilin Northeastern University Boston, MA
Yasuo Tsutsumi Osaka University Osaka, Japan
Susumu Uchiyama Osaka University Osaka, Japan
Guy Van den Mooter Catholic University of Leuven Leuven, Belgium
Geert Verreck Janssen Research & Development Beerse, Belgium
Michel Vert CNRS-University Montpellier 1 Montpellier, France
David Volkin The University of Kansas Lawrence, KS
Jan L. Wahlstrom Amgen, Inc., Seattle, WA
GuanJi Wang China Pharmaceutical University Nanjing, China
Nicholas Warne Pfizer Andover, MA
Timothy Wiedmann University of Minnesota Minneapolis, MN
Adrian C. Williams University of Reading Reading, UK
Gerhard Winter University of Munich Munich, Germany
Samuel H. Yalkowsky University of Arizona Tucson, AZ
Akira Yamamoto Kyoto Pharmaceutical University Kyoto, Japan
Keiji Yamamoto Chiba University Chiba, Japan
Shinji H. Yamashita Setsunan University Osaka, Japan
Hiroshi Yamazaki Showa Pharmaceutical University Tokyo, Japan
Kouichi Yoshinari University of Shizuoka Shizuoka, Japan
Hiroaki Yuasa Nagoya City University Nagoya, Japan
Axel Zeitler University of Cambridge Cambridge, UK
Lucia Zema Università degli Studi di Milano Milan, Italy
Gaylen M. Zentner Comprehensive CMC Outsourcing, LLC Salt Lake City, UT
Cheryl L. Zimmerman University of Minnesota Minneapolis, MN
Scientific Advisors to the Editors Ilgaz Akseli Boehringer-Ingelheim Inc. Ridgefield, CT
Anjali Agrawal Boehringer-Ingelheim Inc. Ridgefield, CT
Alejandra Aguzzi School of Dentistry-UNC Córdoba, Argentina
Kenneth S. Alexander University of Toledo College of Pharmacy Toledo, OH
Fernando Alvarez-Nunez Amgen Inc. Thousand Oaks, CA
Catherine Amiel University Paris Est Thiais, France
Guohua An University of Florida Orlando, FL
Pieter Annaert KU Leuven Leuven, Belgium
Leah Appel Green Ridge Consulting Bend, OR
Muhammad Saeed Arayne University of Karachi Karachi, Pakistan
Robert D. Arnold Auburn University Auburn, AL
Mayssa Attar Allergan, Inc. Irvine, CA
Alejandro Pedro Ayala Federal University of Ceará Fortaleza, Brazil
Raj Badhan Aston University Birmingham, UK
Steven W. Baertschi Eli Lilly & Company Indianapolis, IN
Jane Bai Silver Springs, MD
Kunal Bakshi Pfizer, Inc. Pearl River, NY
Arvind K. Bansal NIPER Mohali, Punjab, India
Sunny Bhardwaj Merck & Co. Kenilworth, NJ
Bakul Bhatnagar Pfizer, Inc. Andover, MD
Jeffrey T. Blue Merck & Co. West Point, PA
Joshua Siaw Boateng University of Greenwich Kent, UK
Prudence Bradley Merck & Co. (retired) Cranford, NJ
Vera Brinks Utrecht University Utrecht, Netherlands
Ira Shea Buckner Duquesne University Pittsburgh, PA
Ting Cai Impax Laboratories Hayward, CA
Shawn Cao Amgen, Inc. Thousand Oaks, CA
Wenjin Cao Amgen, Inc. Thousand Oaks, CA
Stephen M. Carl Unigene Laboratories Fairfield, NJ
Louise Carson Queen’s University Belfast Belfast, Ireland, UK
Keith Chadwick Purdue University West Lafayette, IN
Sayantan Chattoraj GlaxoSmithKline Pharmaceuticals Collegeville, PA
Bodhisattwa Chaudhuri University of Connecticut Storrs, CT
Mao Chen Genentech, Inc. South San Francisco, CA
Xiaodong Chen Bristol-Myers Squibb New Brunswick, JN
Xin Chen Covidien St. Louis, MO
Wei Cheng University of Michigan Ann Arbor, MI
Woei Ping Cheng University of Hertfordshire Hatfield, UK
Po-Chang Chiang Genentech, Inc. South San Francisco, CA
Yite Robert Chou Amgen, Inc. Thousand Oaks, CA
Kwok Chow Covar, Inc. Mississauga, Ontario, Canada
John Chung Amgen, Inc. Thousand Oaks, CA
Maria Jose Cocero Alonso Valladolid University Valladolid, Spain
Intira Coowanitwong Next Breath, LLC Baltimore, MD
John Crison Bristol-Myers Squibb New Brunswick, NJ
Alberto Cuitino Rutgers University Piscataway, NJ
Weiguo Dai Johnson & Johnson Radnor, PA
Lea Ann Dailey King’s College of London London, UK
Sean Dalziel Tobira Therapeutics, Inc. South San Francisco, CA
Rutesh Hemant Dave Long Island University Brooklyn, NY
Vivek S. Dave St. John Fisher College-Wegmans School of Pharmacy Rochester, NY
Anne De Paepe Pfizer Global R & D Sandwich, Kent, UK
Melgardt M. De Villiers University of Wisconsin Madison, WI
Roberto DePaz MedImmune, Inc. Gaithersburg, MD
Xavier Decléves Université Paris Descartes Paris, France
Nunzio Denora University of Bari Bari, Italy
James C. DiNunzio Merck & Co. Summit, NJ
Gemma Dickinson Eli Lilly and Company Indianapolis, IN
Xia Dong Eli Lilly and Company Indianapolis, IN
Daryl C. Drummond Merrimack Pharmaceuticals Cambridge, MA
Christine Dufes University of Strathclyde Glasgow, UK
David A. Engers Engers West Lafayette, IN
Carsten Ehrhardt Trinity College of Dublin Dublin, Ireland
Frank M. Etzler Lake Erie College of Osteopathic Medicine Erie, PA
Kung-I Feng Merck Research Laboratories Rahway, NJ
Qian Feng Tsinghua University Beijing, China
Yushi Feng Eli Lilly and Company Indianapolis, IN
Vito Fodera University of Copenhagen Copenhagen, Denmark
Nikoletta Fotaki University of Bath Calverton Down, Bath, UK
John Gamble Bristol-Myers Squibb Moreton, Merseyside, UK
Marian E. Gindy Merck & Co. West Point, PA
David Goldfarb Merck & Co. Summit, NJ
Yuchuan Gong AbbVie, Inc. North Chicago, IL
Eric M. Gorman Gilead Sciences, Inc. Foster City, CA
Monica Goss Amgen, Inc. Thousand Oaks, CA
Francesca Greco University of Reading Reading, UK
Duoli Guo Forest Research Institute Commack, NY
Manish Gupta GlaxoSmithKline Collegeville, PA
Karen Hapgood Monash University Parkville, Australia
David Harris Merck Research Laboratories Summit, NJ
Andrea Hawe Coriolis Pharma Research Martinsried, Germany
Hisamitsu Hayashi University of Tokyo Tokyo, Japan
Xiaorong He Boehringer-Ingelheim Pharmaceutical, Inc. Ridgefield, CT
Yan He Sanofi Waltham, MA
Jeffrey N. Hemenway Gilead Sciences, Inc. Foster City, CA
Jerry Yong Yew Heng Imperial College London London, England, UK
Paul W.S. Heng National University of Singapore Singapore
Kazutaka Higaki Okayama University Okayama, Japan
John Higgins Merck Research Labs West Point, PA
Nicole Hill Merck & Co. Kenilworth, NJ
Geoffrey Hird Eisai, Inc. Research Triangle Park, NC
Akihiro Hisaka Chiba University Chiba, Japan
Stephen W. Hoag University of Maryland School of Pharmacy Baltimore, MD
Xiao Hu Biogen Idec, Inc. Cambridge, MA
Andrew Ingham Aston University Birmingham, UK
Katsuhisa Inoue Tokyo University of Pharmacy & Life Sciences Hachioji, Tokyo, Japan
Kousei Ito Chiba University Chiba, Japan
Shingo Ito Kumamoto University Kumamoto, Japan
Yasunori Iwao University of Shizuoka Shizuoka, Japan
Akash Jain Cubist Pharmaceuticals Lexington, MA
Yijia Jiang Amgen, Inc. Thousand Oaks, CA
Liang Jin Monash University Melbourne, Australia
Janan Jona Amgen, Inc. Thousand Oaks, CA
Marisa K. Joubert Amgen, Inc. Thousand Oaks, CA
Mouhannad Jumaa Onyx Pharmaceuticals South San Francisco, CA
Toshiya Katsura Ritsumeikan University Kusatsu, Japan
Umesh Kestur Bristol-Myers Squibb New Brunswick, NJ
Dae-Duk Kim Seoul National University Seoul, Republic of Korea
Daniel Jon Kirby Aston University Birmingham, UK
Sandra Klein University of Greifswald Greifswald, Germany
Klaus Knop Heinrich-Heine-University Duesseldorf, Germany
Kaoru Kobayashi Chiba University Chiba, Japan
Otilia May Yue Koo Bristol-Myers Squibb New Brunswick, NJ
Edmund Kostewicz Goethe University Frankfurt, Germany
Mary Krause Echogen, Inc. Lawrence, KS
Michael Kress Merck & Co. West Point, PA
Yoshiyuki Kubo University of Toyoma Toyoma, Japan
Joseph Kushner IV Pfizer, Inc. Groton, CT
Elizabeth C. Kwong Kwong Eureka Solutions Kirkland, Quebec, Canada
Yurong Lai Briston-Myers Squibb Princeton, NJ
Margaret Sue Landis Pfizer, Inc. Groton, CT
Devalina Law AbbVie, Inc. North Chicago, IL
Wooin Lee University of Kentucky Lexington, KY
Yung-Chi Lee Merck Research Laboratories Summit, NJ
Dennis Leung Merck & Co. Rahway, NJ
Z. Jane Li Boehringer-Ingelheim Pharmaceuticals, Inc. Ridgefield, CT
Xiangmin Liao Forest Research Institute Commack, NY
Sreenivas Reddy Lingireddy Eli Lilly and Company Indianapolis, IN
Yitong Liu U.S. Food & Drug Administration Laurel, MD
Sachin Lohani Office of Policy in Pharmaceutical Quality Silver Spring, MD
Enxian Lu Aucta Pharmaceuticals, LLC Monmouth Junction, NJ
Qun Lu Merck & Co. Summit, NJ
Paul Luner Boehringer-Ingelheim Pharmaceuticals, Inc. Ridgefield, CT
Stephen G. Machatha Synageva Biopharma Lexington, MA
Maeda Kazuya University of Toyko Tokyo, Japan
Denny Mahlin Uppsala University Uppsala, Sweden
Heidi M. Mansour University of Arizona-Tucson Tucson, AZ
William A. Marinaro Merck & Co. Summit, NJ
Ivan Marziano Pfizer Worldwide Research & Development Sandwich, UK
Satohiro Masuda Kyoto University Hospital Kyoto, Japan
Caroline McGregor Merck & Co. Boston, MA
Craig McKelvey Merck & Co. West Point, PA
Susan Mercer Lipscomb University Nashville, TN
Jeremy Merritt Eli Lilly and Company Indianapolis, IN
Brian K. Meyer Merck & Co. West Point, PA
Jeffrey W. Millard Oncothyreon Seattle, WA
Danforth Miller Novartis Pharmaceuticals San Carlos, CA
Nazila S. Miller Shire Lexington, MA
Dinesh S. Mishra Eli Lilly and Company Indianapolis, IN
Qingxin Mu University of Kansas Lawrence, KS
Arup Mukkherjee University of Calcutta Kolkata, West Bengal, India
Uwe Muenster Bayer Pharma AG Wuppertal, NRW, Germany
Karthik Nagapudi Amgen, Inc. Simi Valley, CA
Takeo Nakanishi Kanazawa University Kanazawa, Japan
Padma Narayan Dow Chemical Company Freeport, TX
Srividya Neelakantan Biogen Idec, Inc. Cambridge, MA
Seshadri Neervannan Allergan, Inc. Irvine, CA
Tri-Hung Nguyen Monash Institute of Pharmaceuticals Sciences Parkville, Australia
Noriko Ogawa Aichi Gakuin University Nagoya, Japan
Satoshi Ohtake Pfizer, Inc. Chesterfield, MO
Tomoyuki Okuda Meijo University Nagoya, Japan
Takashi Okura Teikyo University Tokyo, Japan
Defang Ouyang University of Macau Macau, China
Gautam Pangu Merck & Co. West Point, PA
James Patterson GlaxoSmithKline Melbourne, Australia
Amrit Paudel University of Leuven Leuven, Belgium
Sathyanarayana R. Perumalla University of Minnesota Minneapolis, MN
Adam Todd Procopio Merck & Co. West Point, PA
Chetan Pujara Allergan, Inc. Irvine, CA
Dongmei Qiang Boehringer-Ingelheim, Inc. Ridgefield, CT
Roger Rajewski University of Kansas Lawrence, KS
Thomas J. Raub Eli Lilly and Company Indianapolis, IN
Clare F. Rawlinson-Malone Briston-Myers Squibb Cheshire, England
Holger Roehl F. Hoffman-LaRoche, LTD Basel-Stadt, Switzerland
Brian R. Rohrs Bausch & Lomb Rochester, NY
Larry Rosen Merck Research Laboratories West Point, PA
Alfred Rumondor Merck & Co. Summit, NJ
Katie Ryan University College Cork Cork, Ireland
Christoph Saal Merck KGaA Darmstadt, Germany
Gregory A. Sacha Baxter BioPharma Solutions Bloomington, IN
Hideyuki Saito Kumamoto University Hospital Kumamoto University, Japan
Robert D. Saklatvala Merck & Co. Rahway, NJ
Atul Saluja Bristol-Myers Squibb New Brunswick, NJ
Giuseppina Sandri University of Pavia Pavia, Italy
Tapan Sanghvi Vertex Pharmaceuticals Cambridge, MA
Jay A. Schrier Pacira Pharmaceuticals, Inc. San Diego, CA
Anna Schwendeman University of Michigan Ann Arbor, MI
Christian Seiler Merck Sharp & Dohme, Ltd Hoddesdon, Herts, UK
Kia Sepassi Johnson & Johnson PRD San Diego, CA
Roman Shimanovich Amgen, Inc. Cambridge, MA
Chinmay Shukla U.S. Food & Drug Administration Silver Spring, MD
Dmitri Simberg University of Colorado Aurora, CO
Andria L. Skinner Regeneron Pharmaceuticals Tarrytown, NY
William Smith Merck & Co. West Point, PA
Phillip Snyder Vertex Pharmaceuticals Cambridge, MA
Im-Sook Song Kyungpook National University Daegu, South Korea
David Spencer MedImmune, LLC Gaithersburg, MD
Omar Sprockel Briston-Myers Squibb New Brunswick, NJ
Alavattam Sreedhara Genentech, Inc. South San Francisco, CA
Oliver Stauch Genentech, Inc. South San Francisco, CA
Roman Szucs Pfizer, Inc. Sandwich, Kent, UK
Tappei Takada University of Tokyo Hospital Tokyo, Japan
Tomohiro Terada Shiga University of Medical Science Hospital Otsu, Shiga, Japan
Marc Tesconi Pfizer, Inc. Groton, CT
Raghu Raj Thakur Queen’s University Belfast Belfast, Northern Ireland
Balakumar Thangaraj Amgen, Inc. Seattle, WA
David Thiriot Merck & Co. West Point, PA
Avinash Thombre Pfizer, Inc. Groton, CT
Markus Thommes University of Deusseldorf Deusseldorf, Germany
Colin Thompson Robert Gordon University Aberdeenshire, Aberdeen, UK
Jay Tibbitts UCB-Celltech Slough, Berkshire, UK
Masatoshi Tomi Keio University Tokyo, Japan
Patrick E. Trapa Pfizer, Inc. Cambridge, MA
Jared M. Trefethen Pfizer, Inc. Pearl River, NY
Natalie L. Trevaskis Monash Institute of Pharmaceutical Sciences Parkville, Australia
Francesco Trotta University of Torino Torino, Italy
Neil Turnbull Pfizer, Inc. Sandwich, Kent, UK
Yasua Uchida Tohoku University Sendai, Japan
Michiel Van Speybroeck FORMAC Pharmaceuticals NV Heverlee, Belgium
Marco van de Weert University of Copenhagen Copenhagen, Denmark
Sitaram Velaga Luleå University of Technology Luleå, Sweden
Matthias Wacker Goethe University Frankfurt, Germany
Randy Wald Bend Research Bend, OR
Paul Walsh Merck & Co. Kenilworth, NJ
John Y. Wang Genentech, Inc. South San Francesco, CA
Zhe Wang National Institute of Health Bethesda, MD
Desmond B. Williams University of South Australia Adelaide, SA Australia
Chuan-Yu Wu University of Surrey Guildford, Surrey, UK
Ke Wu Allergan, Inc. Irvine, CA
Tian Wu Amgen, Inc. Thousand Oaks, CA
Long Xu Regeneron Pharmaceuticals, Inc. Tarrytown, NY
Qingguo Xu Johns Hopkins University Baltimore, MD
Yan Xu Merck Research Laboratories West Point, PA
Fumiyoshi Yamashita Kyoto University Kyoto, Japan
Mehran Yazdanian Teva Pharmaceuticals West Chester, PA
Yoon Yeo Purdue University West Lafayette, IN
Etsuo Yonemochi Hoshi University Shinagawa-ku, Tokyo, Japan
Qi Zhou University of Sydney Sydney, Australia
Li Zhang Centers of Disease Control & Prevention Atlanta, GA
Ming Zhang University of Buffalo Amherst, NY
Junshu Zhao Bristol-Myers Squibb New Brunswick, NJ
Ping Zhao U.S. Food & Drug Administration Silver Spring, MD
Deliang Zhou AbbVie, Inc. North Chicago, IL
Jin Zhou Boehringer-Ingelheim Pharmaceuticals, Inc. Ridgefield, CT
J o u r n a l P r o d u c t i o n
John Wiley & Sons, Inc. Journal of Pharmaceutical Sciences jpsprod@wiley.com
Editor-in-Chief Dr. Ronald T. Borchardt Department of Pharmaceutical Chemistry The University of Kansas 2095 Constant Ave., Room 121c Lawrence, Kansas 66047 Tel: (785) 864-5919 Fax: (785) 864-5875 E-mail: rborchardt@ku.edu or tdunning@ku.edu
Emeritus Editor William Higuchi University of Utah Salt Lake City, UT E-mail: whiguchi@pharm.utah.edu
Editors Bradley D. Anderson University of Kentucky Lexington, KY E-mail: bande2@email.uky.edu
Kenneth L. Audus The University of Kansas Lawrence, KS E-mail: audus@ku.edu
Harry G. Brittain Center for Pharmaceutical Physics Milford, NJ E-mail: hbrittain@centerpharmphysics.com
Ferdinando Giordano Torre d'Isola (Pavia), Italy E-mail: ferdinando.giordano@unipr.it
Michael J. Hageman Bristol-Myers Squibb Co. Princeton, NJ E-mail: michael.hageman@bms.com
Bruno C. Hancock Pfizer, Inc. Groton, CT E-mail: bruno.c.hancock@pfizer.com
Rodney Ho University of Washington Seattle, WA E-mail: rodneyho@uw.edu
C. Russell Middaugh The Universityof Kansas Lawrence, KS E-mail: middaugh@ku.edu
Thomas Rades Copenhagen University København, Denmark E-mail: thomas.rades@sund.ku.dk
Tetsuya Terasaki Tohoku University Sendai, Japan E-mail: terasaki.tetsuya@m.tohoku.ac.jp
Ijeoma F. Uchegbu University of London London, UK E-mail: Ijeoma.uchebgu@pharmacy.ac.uk
Editor of Reviews, Minireviews, General Commentaries, and Special Topic Commentaries John Carpenter University of Colorado Denver Denver, CO E-mail: john.carpenter@ucdenver.edu
Editor of Commentaries on Clinical Trials and Translational Medicine and Global Health Rodney Ho University of Washington Seattle, WA E-mail: rodneyho@u.washington.edu
Editorial Advisory Board Hua Ai Sichuan University Chengdu, P.R. China
Michael J. Akers Akers Consulting Martinsville, IN
Hidetaka Akita Hokkaido University Sapporo City, Japan
Carmen Alvarez-Lorenzo Universidad de Santiago de Compostela Santiago de Compostela, Spain
Gregory E. Amidon University of Michigan Ann Arbor, MI
Thomas J. Anchordoquy Univ. of Colorado Denver Denver, CO
Gavin P. Andrews Queens University Belfast Belfast, Ireland
Per Artursson Uppsala University Uppsala, Sweden
Patrick Augustijns Katholieke Universiteit Leuven Leuven, Belgium
Bruce J. Aungst QPS, LLC Newark, DE
Annette Bak Merck & Co. Rahway, NJ
Joseph Balthasar SUNY - University at Buffalo Buffalo, NY
Sathy V. Balu-Iyer SUNY - University of Buffalo Amherst, NY
James G. Bann Wichita State University Wichita, KS
Jared S. Bee Medlmmune Gaithersburg, MD
Cory Berkland The University of Kansas Lawrence, KS
Joel Bernstein New York University Abu Dhabi Abu Dhabi, United Arab Emirates
Michael Blaber Florida State University Tallahassee, FL
Robin H. Bogner University of Connecticut Storrs, CT
Kathleen MK Boje State University of Buffalo Amherst, NY
Ben J. Boyd Monash University Parkville, Australia
Birger Brodin University of Copenhagen Copenhagen, Denmark
Kenneth R. Brouwer Qualyst Transporter Solutions Durham, NC
James Butler GlaxoSmithKline Research & Development Essex, UK
Stephen R. Byrn Purdue University West Lafayette, IN
Mino R. Caira University of Capetown Rondebosch, South Africa
Carla M. Caramella University of Pavia Pavia, Italy
Adeola O. Coker University of the Incarnate Word San Antonio, TX
Duncan Q.M Craig UCL School of Pharmacy London, UK
John H. Crowe University of California, Davis Davis, CA
Richard T. Darrington Takeda Pharmaceuticals Intl. Co. Cambridge, MA
Martyn C. Davies University of Nottingham Nottingham, UK
Henk J. de Jong Leiden University/FIP Puteaux, France
Sven Deferme PharmaXL Boutersem Belgium
Yoshiharu Deguchi Teikyo University Kanagawa, Japan
Hartmut Derendorf University of Florida Gainesville, FL
Prashant Desai Eli Lilly and Company Indianapolis, IN
Jennifer Dressman Goethe University Frankfurt, Germany
Dave Elder GlaxoSmithKline Ware United Kingdom
Robert K. Evans Merck Research Laboratories West Point, PA
Elias Fattal University of Paris-Sud Châtenay-Malabry, France
Barrie C. Finnin Monash University Parkville, Australia
Mark T. Fisher University of Kansas Medical Center Kansas City, KS
Yatin R. Gokarn Gilead Sciences, Inc. Oceanside, CA
Igor Gonda Aradigm Corporation Hayward, CA
Kosalaram Goteti Medlmmune Gaithersburg, MD
Henrik Gréen Linköping Universitët Linköping, Sweden
Kai Griebenow University of Puerto Rico, Rio Piedras Campus San Juan, Puerto Rico
Richard H. Guy University of Bath Bath, UK
Jonathan Hadgraft University of London London, UK
Margareta Hammarlund-Udenaes Uppsala University Uppsala, Sweden
David J. Hauss Hauss Associates New York, NY
Anthony J. Hickey RTI International Research Triangle Park, NC
Ken-ichi Hosoya University of Toyama Toyama, Japan
Munir Hussain Bristol-Myers Squibb Company New Brunswick, NJ
Tatsuhiro Ishida The University of Tokushima Tokushima, Japan
Ken-ichi Izutsu National Institute of Health Sciences Tokyo, Japan
Wim Jiskoot Leiden University The Netherlands
Kevin C. Johnson Intellipharm, LLC Niantic, CT
David S. Jones Queen's University of Belfast Northern Ireland, UK
LaToya Jones-Braun Regis University Denver, CO
Devendra S. Kalonia University of Connecticut Storrs, CT
Gerald B. Kasting University of Cincinnati Cincinnati, OH
Yukio Kato Kanazawa University Kanazawa, Japan
Bruce A. Kerwin Just Seattle, WA
Filippos Kesisoglou Merck & Co., Inc. West Point, PA
Vitaliy Khutoryanskiy University of Reading Reading, UK
Peter Kleinebudde Heinrich-Heine-University Duesseldorf, Germany
Gregory T. Knipp Purdue University West Lafayette, IN
Janet Koe JGIJ Consulting LLC San Mateo, CA
Hiroyuki Kusuhara The University of Tokyo Tokyo, Japan
William J. Lambert Omeros Corporation Seattle, WA
Majella E. Lane UCL School of Pharmacy London, UK
Robert S. Langer Massachusetts Institute of Technology Cambridge, MA
Jennifer S. Laurence The University of Kansas Lawrence, KS
David Lechuga-Ballesteros Pearl Therapeutics, Inc. Redwood City, CA
Jean-Christophe Leroux Institute of Pharmaceutical Sciences ETH Zürich, Switzerland
Thorsteinn Loftsson Univeristy of Iceland Reykjavik, Iceland
Henry K. Mach Merck Research Laboratories West Point, PA
Hanns-Christian Mahler F. Hoffmann-La Roche Ltd. Basel, Switzerland
Amedeo Marini CSGI - University of Pavia Pavia, Italy
Toru Maruyama Kumamoto University Kumamoto, Japan
Brian E. Mattioni Merch Research Laboratories West Point, PA
Michael B. Maurin Maurin Healthcare Consulting Wilmington, DE
Mark McAllister Pfizer Kent, UK
Gary McGeorge Bristol-Myers Squibb New Brunswick, NJ
Patrick McNamara University of Kentucky Lexington, KY
Natalie Medlicott University of Otago Dunedin, New Zealand
Jan P. Moeschwitzer Next Pharma Berlin, Germany
Marilyn E. Morris University at Buffalo Amherst, NY
Anette Müllertz University of Copenhagen Copenhagen, Denmark
Eric Munson University of Kentucky Lexington, KY
S. Narasimha Murthy The University of Mississippi University, MS
Steven Nail Baxter Medical Products R & D Bloomington, IN
Miki Nakajima Kanazawa University Kanazawa, Japan
Ashwini Nangia University of Hyderabad Hyderabad, India
Linda Owers Narhi Amgen, Inc. Thousand Oaks, CA
Marino Nebuloni REDOX and Parma University Parma, Italy
Thanh Nguyen University College London London, UK
Joseph A. Nicolazzo Monash University Parkville, Australia
Hanne Mørck Nielsen University of Copenhagen Copenhagen, Denmark
Takuo Ogihara Takasaki University of Health & Welfare Gunma, Japan
Sumio Ohtsuki Kumamoto University Kumamoto, Japan
Tetsuya Ozeki Nagoya City University Nagoya, Japan
Jayanth Panyam University of Minnesota Minneapolis, MN
Yvonne Perrie Aston University Birmingham, UK
Michael J. Pikal University of Connecticut Storrs, CT
James E. Polli University of Maryland Baltimore, MD
Christopher J. H. Porter Monash University Melbourne, Australia
Richard J. Prankerd Monash University Parkville, Australia
Theodore W. Randolph University of Colorado Boulder, CO
Jukka Rantanen University of Copenhagen Copenhagen, Denmark
Susan Reutzel-Edens Eli Lilly & Company Indianapolis, IN
Kevin G. Rice University of Iowa Iowa City, IA
Naír Rodríguez-Hornedo The University of Michigan Ann Arbor, MI
Mark C. Rogge Biogen Idec, Inc. Cambridge, MA
Amy Rosenberg Division of Therapeutic Proteins, CDER, FDA Bethesda, MD
Chandrahas Sahajwalla Silver Spring, MD
Yoshimichi Sai Kanazawa University Hospital Kanazawa, Japan
Krishnan Sampath Hospira Inc. Lake Forest, IL
Niklas Sandler Abo Akademi University Turku, Finland
Hitoshi Sasaki Nagasaki University Hospital Nagasaki, Japan
Christian Schöneich The University of Kansas Lawrence, KS
Abu T. M. Serajuddin St. John's University Queens, NY
Danny D. Shen University of Washington Seattle, WA
Teruna J. Siahaan The University of Kansas Lawrence, KS
Satish K. Singh Pfizer, Inc. Chesterfield, MO
Pierre Souillac Shire Lexington, MA
David Spencer Med Immune, Inc. Gaithersburg, MD
Valentino J. Stella The University of Kansas Lawrence, KS
Gregory A. Stephenson Eli Lilly and Company Indianapolis, IN
Audra Stinchcomb University of Kentucky and AllTranz Inc. Lexington, KY
Robert M. Straubinger University at Buffalo Buffalo, NY
Robert Strickley Gilead Sciences, Inc. Foster City, CA
Changquan Calvin Sun University of Minnesota Minneapolis, MN
Raj G. Suryanarayanan University of Minnesota Minneapolis, MN
Masanori Tachikawa Tohoku University Sendai, Japan
David R. Taft Long Island University Brooklyn, NY
Mikihisa Takano Hiroshima University Hiroshima, Japan
Yun K. Tam Sinoveda Canada Inc. Edmonton, Alberta, Canada
Ikumi Tamai Kanazawa University Kanazawa, Japan
Lynne S. Taylor Purdue University West Lafayette, IN
Allen C. Templeton Merck Research Laboratories West Point, PA
Dhiren R. Thakker The University of North Carolina Chapel Hill, NC
Frank-Peter Theil UCB Pharma Brussels, Belgium
Mike Tobyn Bristol-Myers Squibb Moreton, UK
Masatoshi Tomi Keio University Tokyo, Japan
Vladimir Torchilin Northeastern University Boston, MA
Yasuo Tsutsumi Osaka University Osaka, Japan
Susumu Uchiyama Osaka University Osaka, Japan
Guy Van den Mooter Catholic University of Leuven Leuven, Belgium
Geert Verreck Janssen Research & Development Beerse, Belgium
Michel Vert CNRS-University Montpellier 1 Montpellier, France
David Volkin The University of Kansas Lawrence, KS
Jan L. Wahlstrom Amgen, Inc., Seattle, WA
GuanJi Wang China Pharmaceutical University Nanjing, China
Nicholas Warne Pfizer Andover, MA
Timothy Wiedmann University of Minnesota Minneapolis, MN
Adrian C. Williams University of Reading Reading, UK
Gerhard Winter University of Munich Munich, Germany
Samuel H. Yalkowsky University of Arizona Tucson, AZ
Akira Yamamoto Kyoto Pharmaceutical University Kyoto, Japan
Keiji Yamamoto Chiba University Chiba, Japan
Shinji H. Yamashita Setsunan University Osaka, Japan
Hiroshi Yamazaki Showa Pharmaceutical University Tokyo, Japan
Kouichi Yoshinari University of Shizuoka Shizuoka, Japan
Hiroaki Yuasa Nagoya City University Nagoya, Japan
Axel Zeitler University of Cambridge Cambridge, UK
Lucia Zema Università degli Studi di Milano Milan, Italy
Gaylen M. Zentner Comprehensive CMC Outsourcing, LLC Salt Lake City, UT
Cheryl L. Zimmerman University of Minnesota Minneapolis, MN
Scientific Advisors to the Editors Ilgaz Akseli Boehringer-Ingelheim Inc. Ridgefield, CT
Anjali Agrawal Boehringer-Ingelheim Inc. Ridgefield, CT
Alejandra Aguzzi School of Dentistry-UNC Córdoba, Argentina
Kenneth S. Alexander University of Toledo College of Pharmacy Toledo, OH
Fernando Alvarez-Nunez Amgen Inc. Thousand Oaks, CA
Catherine Amiel University Paris Est Thiais, France
Guohua An University of Florida Orlando, FL
Pieter Annaert KU Leuven Leuven, Belgium
Leah Appel Green Ridge Consulting Bend, OR
Muhammad Saeed Arayne University of Karachi Karachi, Pakistan
Robert D. Arnold Auburn University Auburn, AL
Mayssa Attar Allergan, Inc. Irvine, CA
Alejandro Pedro Ayala Federal University of Ceará Fortaleza, Brazil
Raj Badhan Aston University Birmingham, UK
Steven W. Baertschi Eli Lilly & Company Indianapolis, IN
Jane Bai Silver Springs, MD
Kunal Bakshi Pfizer, Inc. Pearl River, NY
Arvind K. Bansal NIPER Mohali, Punjab, India
Sunny Bhardwaj Merck & Co. Kenilworth, NJ
Bakul Bhatnagar Pfizer, Inc. Andover, MD
Jeffrey T. Blue Merck & Co. West Point, PA
Joshua Siaw Boateng University of Greenwich Kent, UK
Prudence Bradley Merck & Co. (retired) Cranford, NJ
Vera Brinks Utrecht University Utrecht, Netherlands
Ira Shea Buckner Duquesne University Pittsburgh, PA
Ting Cai Impax Laboratories Hayward, CA
Shawn Cao Amgen, Inc. Thousand Oaks, CA
Wenjin Cao Amgen, Inc. Thousand Oaks, CA
Stephen M. Carl Unigene Laboratories Fairfield, NJ
Louise Carson Queen’s University Belfast Belfast, Ireland, UK
Keith Chadwick Purdue University West Lafayette, IN
Sayantan Chattoraj GlaxoSmithKline Pharmaceuticals Collegeville, PA
Bodhisattwa Chaudhuri University of Connecticut Storrs, CT
Mao Chen Genentech, Inc. South San Francisco, CA
Xiaodong Chen Bristol-Myers Squibb New Brunswick, JN
Xin Chen Covidien St. Louis, MO
Wei Cheng University of Michigan Ann Arbor, MI
Woei Ping Cheng University of Hertfordshire Hatfield, UK
Po-Chang Chiang Genentech, Inc. South San Francisco, CA
Yite Robert Chou Amgen, Inc. Thousand Oaks, CA
Kwok Chow Covar, Inc. Mississauga, Ontario, Canada
John Chung Amgen, Inc. Thousand Oaks, CA
Maria Jose Cocero Alonso Valladolid University Valladolid, Spain
Intira Coowanitwong Next Breath, LLC Baltimore, MD
John Crison Bristol-Myers Squibb New Brunswick, NJ
Alberto Cuitino Rutgers University Piscataway, NJ
Weiguo Dai Johnson & Johnson Radnor, PA
Lea Ann Dailey King’s College of London London, UK
Sean Dalziel Tobira Therapeutics, Inc. South San Francisco, CA
Rutesh Hemant Dave Long Island University Brooklyn, NY
Vivek S. Dave St. John Fisher College-Wegmans School of Pharmacy Rochester, NY
Anne De Paepe Pfizer Global R & D Sandwich, Kent, UK
Melgardt M. De Villiers University of Wisconsin Madison, WI
Roberto DePaz MedImmune, Inc. Gaithersburg, MD
Xavier Decléves Université Paris Descartes Paris, France
Nunzio Denora University of Bari Bari, Italy
James C. DiNunzio Merck & Co. Summit, NJ
Gemma Dickinson Eli Lilly and Company Indianapolis, IN
Xia Dong Eli Lilly and Company Indianapolis, IN
Daryl C. Drummond Merrimack Pharmaceuticals Cambridge, MA
Christine Dufes University of Strathclyde Glasgow, UK
David A. Engers Engers West Lafayette, IN
Carsten Ehrhardt Trinity College of Dublin Dublin, Ireland
Frank M. Etzler Lake Erie College of Osteopathic Medicine Erie, PA
Kung-I Feng Merck Research Laboratories Rahway, NJ
Qian Feng Tsinghua University Beijing, China
Yushi Feng Eli Lilly and Company Indianapolis, IN
Vito Fodera University of Copenhagen Copenhagen, Denmark
Nikoletta Fotaki University of Bath Calverton Down, Bath, UK
John Gamble Bristol-Myers Squibb Moreton, Merseyside, UK
Marian E. Gindy Merck & Co. West Point, PA
David Goldfarb Merck & Co. Summit, NJ
Yuchuan Gong AbbVie, Inc. North Chicago, IL
Eric M. Gorman Gilead Sciences, Inc. Foster City, CA
Monica Goss Amgen, Inc. Thousand Oaks, CA
Francesca Greco University of Reading Reading, UK
Duoli Guo Forest Research Institute Commack, NY
Manish Gupta GlaxoSmithKline Collegeville, PA
Karen Hapgood Monash University Parkville, Australia
David Harris Merck Research Laboratories Summit, NJ
Andrea Hawe Coriolis Pharma Research Martinsried, Germany
Hisamitsu Hayashi University of Tokyo Tokyo, Japan
Xiaorong He Boehringer-Ingelheim Pharmaceutical, Inc. Ridgefield, CT
Yan He Sanofi Waltham, MA
Jeffrey N. Hemenway Gilead Sciences, Inc. Foster City, CA
Jerry Yong Yew Heng Imperial College London London, England, UK
Paul W.S. Heng National University of Singapore Singapore
Kazutaka Higaki Okayama University Okayama, Japan
John Higgins Merck Research Labs West Point, PA
Nicole Hill Merck & Co. Kenilworth, NJ
Geoffrey Hird Eisai, Inc. Research Triangle Park, NC
Akihiro Hisaka Chiba University Chiba, Japan
Stephen W. Hoag University of Maryland School of Pharmacy Baltimore, MD
Xiao Hu Biogen Idec, Inc. Cambridge, MA
Andrew Ingham Aston University Birmingham, UK
Katsuhisa Inoue Tokyo University of Pharmacy & Life Sciences Hachioji, Tokyo, Japan
Kousei Ito Chiba University Chiba, Japan
Shingo Ito Kumamoto University Kumamoto, Japan
Yasunori Iwao University of Shizuoka Shizuoka, Japan
Akash Jain Cubist Pharmaceuticals Lexington, MA
Yijia Jiang Amgen, Inc. Thousand Oaks, CA
Liang Jin Monash University Melbourne, Australia
Janan Jona Amgen, Inc. Thousand Oaks, CA
Marisa K. Joubert Amgen, Inc. Thousand Oaks, CA
Mouhannad Jumaa Onyx Pharmaceuticals South San Francisco, CA
Toshiya Katsura Ritsumeikan University Kusatsu, Japan
Umesh Kestur Bristol-Myers Squibb New Brunswick, NJ
Dae-Duk Kim Seoul National University Seoul, Republic of Korea
Daniel Jon Kirby Aston University Birmingham, UK
Sandra Klein University of Greifswald Greifswald, Germany
Klaus Knop Heinrich-Heine-University Duesseldorf, Germany
Kaoru Kobayashi Chiba University Chiba, Japan
Otilia May Yue Koo Bristol-Myers Squibb New Brunswick, NJ
Edmund Kostewicz Goethe University Frankfurt, Germany
Mary Krause Echogen, Inc. Lawrence, KS
Michael Kress Merck & Co. West Point, PA
Yoshiyuki Kubo University of Toyoma Toyoma, Japan
Joseph Kushner IV Pfizer, Inc. Groton, CT
Elizabeth C. Kwong Kwong Eureka Solutions Kirkland, Quebec, Canada
Yurong Lai Briston-Myers Squibb Princeton, NJ
Margaret Sue Landis Pfizer, Inc. Groton, CT
Devalina Law AbbVie, Inc. North Chicago, IL
Wooin Lee University of Kentucky Lexington, KY
Yung-Chi Lee Merck Research Laboratories Summit, NJ
Dennis Leung Merck & Co. Rahway, NJ
Z. Jane Li Boehringer-Ingelheim Pharmaceuticals, Inc. Ridgefield, CT
Xiangmin Liao Forest Research Institute Commack, NY
Sreenivas Reddy Lingireddy Eli Lilly and Company Indianapolis, IN
Yitong Liu U.S. Food & Drug Administration Laurel, MD
Sachin Lohani Office of Policy in Pharmaceutical Quality Silver Spring, MD
Enxian Lu Aucta Pharmaceuticals, LLC Monmouth Junction, NJ
Qun Lu Merck & Co. Summit, NJ
Paul Luner Boehringer-Ingelheim Pharmaceuticals, Inc. Ridgefield, CT
Stephen G. Machatha Synageva Biopharma Lexington, MA
Maeda Kazuya University of Toyko Tokyo, Japan
Denny Mahlin Uppsala University Uppsala, Sweden
Heidi M. Mansour University of Arizona-Tucson Tucson, AZ
William A. Marinaro Merck & Co. Summit, NJ
Ivan Marziano Pfizer Worldwide Research & Development Sandwich, UK
Satohiro Masuda Kyoto University Hospital Kyoto, Japan
Caroline McGregor Merck & Co. Boston, MA
Craig McKelvey Merck & Co. West Point, PA
Susan Mercer Lipscomb University Nashville, TN
Jeremy Merritt Eli Lilly and Company Indianapolis, IN
Brian K. Meyer Merck & Co. West Point, PA
Jeffrey W. Millard Oncothyreon Seattle, WA
Danforth Miller Novartis Pharmaceuticals San Carlos, CA
Nazila S. Miller Shire Lexington, MA
Dinesh S. Mishra Eli Lilly and Company Indianapolis, IN
Qingxin Mu University of Kansas Lawrence, KS
Arup Mukkherjee University of Calcutta Kolkata, West Bengal, India
Uwe Muenster Bayer Pharma AG Wuppertal, NRW, Germany
Karthik Nagapudi Amgen, Inc. Simi Valley, CA
Takeo Nakanishi Kanazawa University Kanazawa, Japan
Padma Narayan Dow Chemical Company Freeport, TX
Srividya Neelakantan Biogen Idec, Inc. Cambridge, MA
Seshadri Neervannan Allergan, Inc. Irvine, CA
Tri-Hung Nguyen Monash Institute of Pharmaceuticals Sciences Parkville, Australia
Noriko Ogawa Aichi Gakuin University Nagoya, Japan
Satoshi Ohtake Pfizer, Inc. Chesterfield, MO
Tomoyuki Okuda Meijo University Nagoya, Japan
Takashi Okura Teikyo University Tokyo, Japan
Defang Ouyang University of Macau Macau, China
Gautam Pangu Merck & Co. West Point, PA
James Patterson GlaxoSmithKline Melbourne, Australia
Amrit Paudel University of Leuven Leuven, Belgium
Sathyanarayana R. Perumalla University of Minnesota Minneapolis, MN
Adam Todd Procopio Merck & Co. West Point, PA
Chetan Pujara Allergan, Inc. Irvine, CA
Dongmei Qiang Boehringer-Ingelheim, Inc. Ridgefield, CT
Roger Rajewski University of Kansas Lawrence, KS
Thomas J. Raub Eli Lilly and Company Indianapolis, IN
Clare F. Rawlinson-Malone Briston-Myers Squibb Cheshire, England
Holger Roehl F. Hoffman-LaRoche, LTD Basel-Stadt, Switzerland
Brian R. Rohrs Bausch & Lomb Rochester, NY
Larry Rosen Merck Research Laboratories West Point, PA
Alfred Rumondor Merck & Co. Summit, NJ
Katie Ryan University College Cork Cork, Ireland
Christoph Saal Merck KGaA Darmstadt, Germany
Gregory A. Sacha Baxter BioPharma Solutions Bloomington, IN
Hideyuki Saito Kumamoto University Hospital Kumamoto University, Japan
Robert D. Saklatvala Merck & Co. Rahway, NJ
Atul Saluja Bristol-Myers Squibb New Brunswick, NJ
Giuseppina Sandri University of Pavia Pavia, Italy
Tapan Sanghvi Vertex Pharmaceuticals Cambridge, MA
Jay A. Schrier Pacira Pharmaceuticals, Inc. San Diego, CA
Anna Schwendeman University of Michigan Ann Arbor, MI
Christian Seiler Merck Sharp & Dohme, Ltd Hoddesdon, Herts, UK
Kia Sepassi Johnson & Johnson PRD San Diego, CA
Roman Shimanovich Amgen, Inc. Cambridge, MA
Chinmay Shukla U.S. Food & Drug Administration Silver Spring, MD
Dmitri Simberg University of Colorado Aurora, CO
Andria L. Skinner Regeneron Pharmaceuticals Tarrytown, NY
William Smith Merck & Co. West Point, PA
Phillip Snyder Vertex Pharmaceuticals Cambridge, MA
Im-Sook Song Kyungpook National University Daegu, South Korea
David Spencer MedImmune, LLC Gaithersburg, MD
Omar Sprockel Briston-Myers Squibb New Brunswick, NJ
Alavattam Sreedhara Genentech, Inc. South San Francisco, CA
Oliver Stauch Genentech, Inc. South San Francisco, CA
Roman Szucs Pfizer, Inc. Sandwich, Kent, UK
Tappei Takada University of Tokyo Hospital Tokyo, Japan
Tomohiro Terada Shiga University of Medical Science Hospital Otsu, Shiga, Japan
Marc Tesconi Pfizer, Inc. Groton, CT
Raghu Raj Thakur Queen’s University Belfast Belfast, Northern Ireland
Balakumar Thangaraj Amgen, Inc. Seattle, WA
David Thiriot Merck & Co. West Point, PA
Avinash Thombre Pfizer, Inc. Groton, CT
Markus Thommes University of Deusseldorf Deusseldorf, Germany
Colin Thompson Robert Gordon University Aberdeenshire, Aberdeen, UK
Jay Tibbitts UCB-Celltech Slough, Berkshire, UK
Masatoshi Tomi Keio University Tokyo, Japan
Patrick E. Trapa Pfizer, Inc. Cambridge, MA
Jared M. Trefethen Pfizer, Inc. Pearl River, NY
Natalie L. Trevaskis Monash Institute of Pharmaceutical Sciences Parkville, Australia
Francesco Trotta University of Torino Torino, Italy
Neil Turnbull Pfizer, Inc. Sandwich, Kent, UK
Yasua Uchida Tohoku University Sendai, Japan
Michiel Van Speybroeck FORMAC Pharmaceuticals NV Heverlee, Belgium
Marco van de Weert University of Copenhagen Copenhagen, Denmark
Sitaram Velaga Luleå University of Technology Luleå, Sweden
Matthias Wacker Goethe University Frankfurt, Germany
Randy Wald Bend Research Bend, OR
Paul Walsh Merck & Co. Kenilworth, NJ
John Y. Wang Genentech, Inc. South San Francesco, CA
Zhe Wang National Institute of Health Bethesda, MD
Desmond B. Williams University of South Australia Adelaide, SA Australia
Chuan-Yu Wu University of Surrey Guildford, Surrey, UK
Ke Wu Allergan, Inc. Irvine, CA
Tian Wu Amgen, Inc. Thousand Oaks, CA
Long Xu Regeneron Pharmaceuticals, Inc. Tarrytown, NY
Qingguo Xu Johns Hopkins University Baltimore, MD
Yan Xu Merck Research Laboratories West Point, PA
Fumiyoshi Yamashita Kyoto University Kyoto, Japan
Mehran Yazdanian Teva Pharmaceuticals West Chester, PA
Yoon Yeo Purdue University West Lafayette, IN
Etsuo Yonemochi Hoshi University Shinagawa-ku, Tokyo, Japan
Qi Zhou University of Sydney Sydney, Australia
Li Zhang Centers of Disease Control & Prevention Atlanta, GA
Ming Zhang University of Buffalo Amherst, NY
Junshu Zhao Bristol-Myers Squibb New Brunswick, NJ
Ping Zhao U.S. Food & Drug Administration Silver Spring, MD
Deliang Zhou AbbVie, Inc. North Chicago, IL
Jin Zhou Boehringer-Ingelheim Pharmaceuticals, Inc. Ridgefield, CT
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