The Journal of Chromatography B publishes papers on developments in separation science relevant to biology and biomedical research including both fundamental advances and applications. Analytical techniques which may be considered include the various facets of chromatography, electrophoresis and related methods, affinityand immunoaffinity-based methodologies, hyphenated and other multi-dimensional techniques, and microanalytical approaches. The journal also considers articles reporting developments in sample preparation, detection techniques including mass spectrometry, and data handling and analysis.

Developments related to preparative separations for the isolation and purification of components of biological systems may be published, including chromatographic and electrophoretic methods, affinity separations, field flow fractionation and other preparative approaches.

Applications to the analysis of biological systems and samples will be considered when the analytical science contains a significant element of novelty, e.g. a new approach to the separation of a compound, novel combination of analytical techniques, or significantly improved analytical performance. Areas to be considered include:
The qualitative and quantitative analysis of biopolymers including proteins, monoclonal antibodies, peptides and their post-translational modifications as well as nucleic acids and glycans
The comparative analysis of biological systems using proteomics, genomics, metabolomics, lipidomics and other "omics" approaches
Clinical analysis, metabolism, therapeutic drug monitoring, toxicological analysis, doping analysis, veterinary applications, analysis of environmental contaminants in biological systems
The screening and profiling of body fluids, tissues, cells, biological matrices and systems, analysis of endogenous compounds, biomarkers
Identification of new bioactive compounds


Applications which utilize published or commercial analytical or preparative protocols with little or no modification or where the results of the application rather than the analytical methodology comprise the major element of novelty of the manuscript should be directed to more specialized journals. Modifications to a previously published method may be considered for a short communication in cases where the improvement in performance is significant. Reports of analytical methods for compounds in early pharmaceutical development often lack general interest and will not be published unless the authors can demonstrate the broader significance of the methodology involved. Quality control analyses of bulk drugs, natural products or pharmaceutical formulations of small molecules are not within scope.

Regular research papers (full-length papers), Review articles, Short Communications, Protocols, Discussions, Letters to the Editor

Editor-in-Chief
David S. Hage
University of Nebraska-Lincoln, Lincoln, Nebraska, United States Affinity chromatography; Immunoaffinity chromatography; High-performance affinity chromatography; Affinity capillary electrophoresis; Theory of chromatography; Theory of electrophoresis; Support development of high performance liquid chromatography; Immobilization methods for biomolecules; MonolithsChromatographic immunoassays; Drug-protein binding; Biological interaction analysis; Chiral separations; Personalized medicine; Microscale affinity systems
Editors
Davy Guillarme
University of Geneva, Geneva, Switzerland Chromatography in general; LC-MS; SFC-MS; Characterization of proteins biopharmaceuticals; Intact proteins analysis; Analysis of drugs in biofluids; Doping control analysis
Ping Li
China Pharmaceutical University, Nanjing, China
Govert Somsen
VU Amsterdam, Amsterdam, Netherlands Hyphenation in separation science; Liquid chromatography; Capillary electrophoresis; LC-MS; CE-MS; Fluorescence detection; On-line sample preparation; Chiral separations; Protein and peptide analysis; Biopharmaceuticals; Metabolic profiling; Bioactivity screening
Georgios Theodoridis
Aristotle University of Thessaloniki, Thessaloniki, Greece Metabolomics; Biomarkers; Bioanalysis; Analytical toxicology; LC-MS; GC-MS; Affinity separations
Dimitrios Tsikas
Hannover Medical School, Hannover, Germany Gas chromatography, Liquid chromatography, Mass spectrometry; Sample preparation and derivatization; Stable isotopes; Quantitative bioanalysis; Method validation and comparison; Amino acids and polyamines; Fatty acids and eicosanoids; Clinical Pharmacology and toxicology; Oxidative and nitrosative stress; Human disease mechanisms; Renal and cardiovascular systems; Posttranslational protein modifications; Low-molecular-mass biomarkers
Christina Virgiliou, PhD
Aristotle University of Thessaloniki, Thessaloniki, Greece
Thematic Volume Editors
Ian D. Wilson
Imperial College London, London, United Kingdom
Editorial Advisory Board
Pedro Araujo
Institute of Marine Research, Bergen, Norway
Joseph H. Banoub
Fisheries and Oceans Canada Newfoundland and Labrador Region, St John's, Newfoundland and Labrador, Canada
Michael Bartlett
The University of Georgia, Athens, Georgia, United States
Rainer Bischoff
University of Groningen, Groningen, Netherlands
Eric Chun Yong Chan, PhD
National University of Singapore, Singapore, Singapore
Yi Chen
Chinese Academy of Sciences, Beijing, China
Ersilia De Lorenzi
University of Pavia, Pavia, Italy
Les Edinboro, MS, PhD, F-ABFT
Quest Diagnostics Nichols Institute, San Juan Capistrano, California, United States
András Guttman
University of Debrecen, Debrecen, Hungary
Kenji Hamase
Kyushu University, Fukuoka, Japan
Paul Ho
National University of Singapore, Singapore, Singapore
Gérard Hopfgartner
University of Geneva, Geneva, Switzerland
Christian Huber
University of Salzburg, Salzburg, Austria
Joachim Jankowski
RWTH Aachen University, Aachen, Germany
Thomas Karnes
Virginia Commonwealth University, Richmond, Virginia, United States
Uwe Karst
University of Münster, Munster, Germany
Wolfgang Lindner
University of Vienna, Wien, Austria
Hans Maurer
Universitat des Saarlandes Institut fur Experimentelle und Klinische Pharmakologie und Toxikologie, Homburg, Germany
David Muddiman
North Carolina State University, Raleigh, North Carolina, United States
Frank Peters
Jena University Hospital Institute of Legal Medicine, Jena, Germany
Adam S. Ptolemy
Dynacare, London, Ontario, Canada
Feng Qiu
Tianjin University of Traditional Chinese Medicine, Tianjin, China
Ranieri Rossi
University of Siena, Siena, Italy
Rolf Sparidans
Utrecht University, Utrecht, Netherlands
Tung-Hu Tsai
National Yang Ming University Department of Chemical Engineering, Miaoli, Taiwan
Peng-Fei Tu
Peking University School of Pharmaceutical Sciences, Beijing, China
Irving Wainer
National Institute on Aging Bioanalytical Chemistry and Drug Discovery Section, Baltimore, Maryland, United States
Guowang Xu
Dalian Institute of Chemical Physics, Dalian, China
Dafang Zhong
Shanghai Institute of Materia Medica Chinese Academy of Sciences, Shanghai, China