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成果及论文



29. Visible-Light-Driven Carboxylative 1,2-Difunctionalization of C=C Bonds with Tetrabutylammonium Oxalate

      Sai Wang,∇ Pei Xu,∇ Zhi-Tao Liu, Yi-Qin Liu, Hao-Qiang Jiang, Tian-Zi Hao, Hui-Xian Jiang, Hui Xu,

      Xu-Dong Cao,* Dong Guo,* and Xu Zhu*

      ACS Central Sci, accepted, doi.org/10.1021/acscentsci.4c01464

      


28. Photo-Induced Radical Approach for Desulfurative Alkylation of Cysteine Derivatives to Making Unnatural Amino Acids

     Pei Xu,,* Yi-Qin Liu, Hui-Xian Jiang, Tian-Zi Hao, Si-Yi Yan, Zhi-Tao Liu, Xu Zhu* 

     Org. Lett. 2024, 26, 8854-8859.

      


27. 可见光诱导甲酸盐参与的炔烃氢羧基化反应 (Visible-Light-Induced Selective Hydrocarboxylation of Alkynes with Formate)

      徐辉†,蒋慧娴†,阚磊,徐佩,朱旭*

      有机化学,invited contribution,2024, 44, doi: 10.6023/cjoc202405025, 封面文章

      


26. Chen-Wei Xu (本科生),‡ Si-Yi Yan(本科生),‡ Hui Xu, Sai Wang, Li-Qun Gu, Pei Xu, Long Yin, Xu Zhu*

      Photoredox-Neutral Deoxygenative Carboxylation of Acylated Alcohols with Tetrabutylammonium Oxalate

      ACS Catal. 2024, 14, 11967-11973.

      


25. Pei Xu,† Hao-Qiang Jiang,† Hui Xu,† Sai Wang,  Hui-Xian Jiang, Song-Lei Zhu, Long Yin,*, Dong Guo,*  Xu Zhu*

     Photocatalytic Deuterocarboxylation of Alkynes with Oxalate

     Chem. Sci. 2024, 15, 13041-13048.

     


24. Wen-Wen Liu,# Pei Xu,# Hui-Xian Jiang, Meng-Lei Li, Tian-Zi Hao, Yi-Qin Liu, Song-Lei Zhu, Kun-Xiao Zhang,* and Xu Zhu*

      Photochemical Reductive Carboxylation of N-Benzoyl Imines with Oxalate Accelerated by Formation of EDA Complexes

      ACS Catal. 2024, 14, 10053-10059. Highlighted by Chin. Chem. Lett.

      


23. Pei Xu,† Wen-Wen Liu,† Tian-Zi Hao, Yi-Qin Liu, Hui-Xian Jiang, Jing Xu, Jin-You Li, Long Yin,* Song-Lei Zhu,* Xu Zhu*

     Formate and CO2 Enable Reductive Carboxylation of Imines: Synthesis of Unnatural α-Amino Acids

     J. Org. Chem. 2024, 89, 9750-9754. Highlighted by Synfacts

     

22. Xing-Yu Wang#, Pei Xu#, Wen-Wen Liu, Hao-Qiang Jiang, Song-Lei Zhu*, Dong Guo* & Xu Zhu*

     Divergent Defluorocarboxylation of α-CF3 Alkenes with Formate via Photocatalyzed Selective Mono- or Triple C-F Bond Cleavage

     Sci. China. Chem, 2024, 67,368-373. doi.org/10.1007/s11426-023-1731-x, ESI highly cited paper

      Hightlighted by 化学加

      


21. Wang, S.; Xu, P.*; Zhu, X.* (Invited Concept)

      CO2 Radical Anion in Photochemical Dicarboxylation of Alkenes. 

      ChemCatChem, 2023, e202300695, doi.org/10.1002/cctc.202300695

      Highlighted by WileyChem

      


20. Xu, P.; Xu, H.; Wang, S.; Hao, T.-Z.; Yan, S-Y.; Guo, D.*; Zhu, X.* 

        Transition-metal Free Oxidative Carbo-carboxylation of Alkenes with Formate in Air. 

        Org. Chem. Front. 202310,2013-2017

         Highlighted by Organic Chemistry Frontiers

         


19. Xu, P.; Wang, S.; Xu, H.; Liu, Y.; Li, R.-B.; Liu, W.-W.; Wang, X.-Y.; Zou, M.-L.; Zhou, Y.; Guo, D.*; Zhu, X.* 

        Dicarboxylation of Alkenes with CO2 and Formate via Photoredox Catalysis.

       ACS Catal. 2023, 13(3), 2149-2155

       Highlighted by CBG 

        


18. Xu, P.; Wang, X.-Y.; Wang, Z.; Zhao, J.; Cao, X.-D.; Xiong, X.-C.; Yuan, Y.-C.; Zhu, S.*; Guo, D.*; Zhu, X.*  

       Defluorinative Alkylation of Trifluoromethyl- benzimidazoles Enabled by Spin-Center Shift: A Synergistic Photocatalysis/Thiol Catalysis Process with CO2•–

        Org. Lett., 2022, 24(22), 4075-4080. 

         


17.  Xudong Cao,§ Peng Wang,§ Haoxing Yuan,§ Haoran Zhang, Yan He, Kequan Fu, Qian Fang, Hongli Liu, Limin Su, Long Yin, Pei Xu,    Yuyang Xie, Xiaochun Xiong, Junqi Wang,* Xu Zhu,* and Dong Guo.*

Benzodiazepine Derivatives as Potent Vasopressin V2 Receptor Antagonists for the Treatment of Autosomal Dominant Kidney Disease

J. Med. Chem. 2022, 65, 9295-9311.

Prior to Xuzhou Medical University

16. Romero, K. J.; Keylor, M. H.; Markus Griesser, M.; Zhu, X.; Strobel, E. J.; Pratt, D. A.; Stephenson, C. R. J. 

         Synthesis of vitisin A & D enabled by a persistent radical equilibrium.

        J. Am. Chem. Soc. 2020, 142(14), 6499-6504.  

15.   Zhu, X. #; McAtee, C. C. #(共同一作); Schindler, C. S.* 

       Total syntheses of herqulines B and C.”

        J. Am. Chem. Soc. 2019, 141 (8), 3409-3413. 

14.  Zhu, X. ; McAtee, C. C.; Schindler, C. S.* 

       Scalable synthesis of mycocyclosin.”

       Org. Lett. 2018, 20 (10), 2862-2866. 

13.  Zhu, X.; Chiba, S.

      Copper-catalyzed oxidative carbon–heteroatom bond formation: a recent update.” 

      Chem. Soc. Rev. 2016, 45 (16), 4504-4523.  97次引用

12.  Zanda, M.; Zhu, X.; McAtee, C. C.; Schindler, C. S.* 

      Total syntheses of herqulines B and C". 

       Synlett. 2019, 30 (11), A102-A105

11.  Keylor, M. H.; Matsuura, B. S.; Griesser, M.; Chauvin, J-P. R.; Harding, R. S.; Kirillova, M. S.; Zhu, X.; Fischer, O. J.; Pratt, D. A.; Stephenson, C. R. J.

       Synthesis of resveratrol tetramers via a stereoconvergent radical equilibrium.” 

       Science 2016, 354 (6317), 1260-1265

10.  Zhu, X.; Chiba, S.* 

      Construction of 1-pyrroline skeletons by Lewis acid-mediated conjugate addition of vinyl azides.” 

      Chem. Commun. 2016, 52 (12), 2473-2476. 

9.   Zhang, F-L.#; Zhu, X. #(共同一作),Chiba, S.* 

      Tf2NH-catalyzed amide synthesis from vinyl azides and alcohols.” 

      Org. Lett. 2015, 17 (12), 3138-3141.  

8.  Zhu, X.; Chiba, S.*

     TEMPO-mediated allylic C–H amination with hydrazones.” 

     Org. Biomol. Chem. 2014, 12 (26), 4567-4570.  

7.  Zhu, X.; Wang, Y-F.; Zhang, F-L.; Chiba, S.* 

     Formal [4+2]-annulation of vinyl azides with N-unsaturated aldimines.” 

     Chem. Asian J. 2014, 9 (9), 2458-2462.  

6.  Zhang, F-L.; Wang, Y-F.; Lonca, G. H.; Zhu, X.; Chiba, S.* 

     Amide synthesis by nucleophilic attack of vinyl azides.” 

      Angew. Chem. Int. Ed. 2014, 53 (17), 4390-4394. 

5.  Zhu, X.; Wang, Y-F.; Ren, W.; Zhang, F-L.; Chiba, S.* 

     TEMPO-mediated aliphatic C–H oxidation with oximes and hydrazones.” 

     Org. Lett. 2013, 15 (13), 3214-3217. 

4.   Wang, Y-F.#; Zhu, X.# (共同一作); Chiba, S.* 

      Copper-catalyzed aerobic [3+2]-annulation of N-alkenyl amidines.

      J. Am. Chem. Soc. 2012, 134 (8), 3679-3682. 

3.  Wang, Y-F. #; Chen, H. #(共同一作); Zhu, X.; Chiba, S.* 

     Copper-catalyzed aerobic aliphatic C–H oxygenation directed by an amidine moiety.” 

     J. Am. Chem. Soc. 2012, 134 (29), 11980-11983.

2.  Zhu, X.; Xu, X-P.*; Sun, C.; Chen, T.; Shen, ZL.; Ji, S-J.* 

     I-MCR-Ullmann cascade toward furo [2, 3-b] indole scaffold.” 

     Tetrahedron 2011, 67 (34), 6375-6381.  

1.  Zhu, X.; Xu, X-P.*; Sun, C.; Zhao, K.; Ji, S-J.* 

     Direct construction of imino-pyrrolidine-thione scaffold via isocyanide-based Multicomponent reaction.

     J. Comb. Chem. 2010, 12 (6), 822-828.