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成果及论文

Peer Reviewed Articles:  

40. Coming soon......

39. Xinyue Xie, Yang Li(本科生), Zhaoyang Zhang,Wenkun Luo,Jun Zhou*. Silver-Mediated Aromatic C-H Alkylation with Secondary or Tertiary Alkyl-Bromine Bonds for the Construction of Indolones.(In preparation). 

38. Zhaoyang Zhang,Wenkun Luo, Jun Zhou*.Silver-Mediated Alkylation of O-Silyl Enol Ethers with α-Carbonyl Alkyl Bromides to Access 4-Oxobutanoates.(In preparation).

37. Fen Huang,Jing Tang,Wenkun Luo, Jun Zhou*.Silver-Mediated ipso-Carbocyclization of N-Arylpropiolamides for the Synthesisi of Azaspiro[4.5] Trienones. .(In preparation).

36. Jing Tang,Fen Huang,Weiwei Luo, Jun Zhou*.Silver-Mediated ipso-Carbocyclization of N-Benzoyl Acrylamides  Leading to Azaspiro[4.5] Dienones. (In preparation).

35. Fen Huang+, Zhijun Ren+, Xiaoting Gan, Jing Tang, Weiwei Luo, Jun Zhou*. Silver-Mediated Alkylarylation of Alkenes with Dual C–H Bonds of Arenes and Chloro-malonic ester toward Chloro-substituted Oxindoles Bearing two Quaternary Carbon Centers.(In preparation+Contributed equally).

34. Xiaoting Gan, Xuchang Miu, Lexuan Ji(本科生), Dachao Wang, Zhijun Ren, Wenkun Luo, Jun Zhou*. Fe-Catalyzed Tandem Tert-alkylation C−H Cyclization of α-Bromocarbonyls to Synthesize Substituted Oxindoles.(In preparation).


33.  Zhijun Ren+, Xiaoting Gan+, Jing Tang+, Fen Huang+,Dachao Wang, Xinyue Xie, Yang Li(本科生), Wenkun Luo, Weiwei Luo, Jun Zhou*. Silver-Mediated One-Electron Reduction of α-Carbonyl Alkyl Bromides Followed by Alkyl-Arylation of Acrylamides: Expeditious Synthesis of Acetylcholine Esterase  Inhibitors.  http://www.paper.edu.cn/releasepaper/content/202203-409(To be submitted+Contributed equally).

32. Xiaoqin Gao,Weiwei Luo, Jun Zhou*.Synthesis of Bulky 1,1-Diarylalkanes by Silver-Mediated 1,2-Alkylarylation of Styrenes with α-Carbonyl Alkyl Bromides and Arenes involving C-H Functionalization.(In preparation).


31. Xuchang Miu, Man Liu,Weiwei Luo, Jun Zhou*.K2S2O8-Mediated Allylation Reaction of Allylic Alcohols with Alcohols to Access Allylic β,γ-Unsaturated Ethers.(In preparation).


30. Wenkun Luo*, Huiling Jiang, Weiwei Luo, Chao Liu, Jun Zhou*Halogen Radical enabled Dearomatization of N-arylpropiolamides via Photoinduced Sequential Halogenation/Spirocyclization/Oxidation Process.(Under Review)


29. Weiwei Luo*, Yu Zhang, Meijun Ming, Lin Zhang. Recent advances in the catalytic asymmetric construction of axially chiral azole-based frameworks.Org. Chem. Front. 2024, DOI:10.1039/D4QO01705F.  


28. Xinyue Xie, Shiyin Zhao, Yingzi Li*, Jun Zhou*, and Feng Zhu*. Merging Single- and Two-electron Strategies for the Stereoselective Synthesis of Aryl Amide N-Glycosides via Photoredox Palladium-Catalyzed Aminocarbonylations. Chem Catalysis 20244, 101109. 【报道】https://mp.weixin.qq.com/s/xo_Z2pXeDTEniQGMsk7WKQ

27. Zhaoyang Zhang,Weiwei Luo, Jun Zhou*. Research Progress of Radical Reactions Involving Silyl Enol Ether.(烯醇硅醚参与的自由基反应研究进展)。Chin. J. Org. Chem  2024, 44, 2658-2681. 【报道】https://mp.weixin.qq.com/s/I0eKeDkI6e4v-rHB5JuiEA

 26. Weiwei Luo*, Huanhuan Guo, Xueying Qiu, Meijun Ming, Lin Zhang, Hao Zhu, Jun Zhou*. Organocatalytic Atroposelective Construction of Pentatomic Heterobiaryl Diamines through Arylation of 5-Aminoisoxazoles with Azonaphthalenes. Org. Lett. 2024, 26,  2564–2568【报道】https://mp.weixin.qq.com/s/GcwguqhSLVH-RSOYanxOzw

25Fen Long, Kai Jiang, Weiwei Song, Wenkun Luo*, Biaolin Yin* Photoinduced Pd-Catalyzed Dearomative 2,5-Difunctionalizition of Furans via Cascade C–C/C–O Bond Formation. Org. Lett. 202426, 5, 1083-1087

24. Jing Tang,Wenkun Luo, Jun Zhou*. Advances in the Synthesis of Azaspiro[4.5] Trienones.(氮杂螺[4.5]三烯酮衍生物的合成研究进展)Chin. J. Org. Chem 2023,43(9), 3006-3034.

23. Fen Huang, Weiwei Luo, Jun Zhou.* Research Progress of Polychloroalkylation Based on C-H Bond Cleavage(基于C-H键断裂的多氯烷基化反应研究进展)Chin. J. Org. Chem 2023,43(7), 2368-2390

22.  Zhijun Ren, Weiwei Luo, Jun Zhou*. Recent Progress in Silver-Mediated Tandem Cyclization of N-Arylacrylamides(银介导的N-芳基丙烯酰胺串联环化反应研究进展). Chin. J. Org. Chem 2023, 43(6), 2026-2039。(封面文章)

21Jose Cortes Vazquez, Waad S. Alharbi, Jacqkis Davis, Alexia Moore, Vladimir N. Nesterov, Thomas R. Cundari, Hong Wang*, Weiwei Luo*. Three Component Cascade Reaction of Cyclohexanones, Aryl Amines, and Benzoylmethylene Malonates: Cooperative Enamine-Brønsted Acid Approach to Tetrahydroindoles. ACS Omega 2022, 7, 49, 45341–45346.

 

20. Jacqkis Davis, Mojgan Gharaee, Dr. Chamini V. Karunaratne, Jose Cortes Vazquez, Mikayla Haynes, Weiwei Luo, Vladimir N. Nesterov, Thomas Cundari*, Hong Wang*. Asymmetric Synthesis of Chromans Through Bifunctional Enamine-Metal Lewis Acid Catalysis. Chem. Eur. J. 2022, 28, e2022002.

19. Wenkun Luo*,  Kai Jiang, Biaolin Yin*.Copper-Initiated Radical Dearomative 2,5-Alkylarylation of Furans via Trihalomethylation/Spirocyclization Cascade. Chin. J. Chem. 2022, 40, 2893-2899.

18. Xiaoting Gan, Fen Huang, Zhijun Ren, Bo Li, Shaojie Chen(本科生), Wenkun Luo, Jun Zhou*. Efficient Access to Multi-substituted 1-Amino Isoquinolines via Rh(III)-Catalyzed Oxidative Annulation of Aminopyridine Pivalamides with Internal Alkynes.Tetrahedron Letters 2022,103,153970

    

17.  Dachao Wang, Xiaoting Gan, Lewei Zhou, Hanyu Shu(本科生), Jun Zhou*. Synthesis of Functionized N-arylbenzotriazoles via Palladium Catalyzed Intramolecular Amination. http://www.paper.edu.cn/releasepaper/content/202108-47Tetrahedron Letters 2022,88,153587.   

        


16. Jose Cortes Vazquez, Jacqkis Davis, Vladimir N. Nesterov, Hong Wang*, Weiwei Luo*. Sc(OTf)3-Catalyzed Formal [3 + 3] Cycloaddition Reaction of Diaziridines and Quinones for the Synthesis of Benzo[e][1,3,4]oxadiazines. Org. Lett. 2021, 23, 3136−3140. 【报道】 https://www.chembeango.com/zixun/54678https://mp.weixin.qq.com/s/GcwguqhSLVH-RSOYanxOzw

15.  E. H. Nisala Fernando, Jose Cortes Vazquez, Jacqkis Davis, Weiwei Luo, Vladimir N. Nesterov,  Hong Wang*.Can Primary Arylamines Form Enamine? Evidence, α-Enaminone, and [3+3] Cycloaddition Reaction. J. Org. Chem. 2021, 86, 14617–14626.

14.  Jialiang Qin, Yili Zhang, Cuiting Liu, Jun Zhou, Ruoting Zhan, Weiwen Chen, Huicai Huang*. Asymmetric Inverse-Electron-Demand Diels–Alder Reaction of β,γ-Unsaturated Amides through Dienolate Catalysis.Org. Lett., 2019, 21, 7337


       

13. Lei Liu, Wes Lee, Jun Zhou, Surjo Bandyopadhyay, Osvaldo Gutierrez*. Radical-clock α-halo-esters as mechanistic probes for bisphosphine iron-catalyzed cross-coupling reactions. Tetrahedron 2019, 2, 129.

                                             

12. Jun Zhou, Xing Li, Gang Liao, Bing-Feng Shi*. Rhodium(III)-Catalyzed C–H Vinylation of Arenes: Access to Functionalized Styrenes. Chin. J. Chem. 201836, 1143.

                                              

11. Wes Lee, Jun Zhou, Osvaldo Gutierrez*. Mechanism of Nakamura’s Bisphosphine Iron-Catalyzed Asymmetric C(sp2)-C(sp3) Cross-Coupling Reaction: The Role of Spin in Controlling Arylation Pathways. J. Am. Chem. Soc2017139, 16126

                                             

10. Jun Zhou, Peng-Xiang, Ling, Bo Li, Bing-Feng Shi*. Synthesis of 3,4-dihydro-1,8-naphthyridin-2(1H)-one. Highlights of Sciencepaper Online, 2016, 9, 1293. (Published online: http://www.paper.edu.cn/releasepaper/content/201512-434)

                                             

9. Jun Zhou, Shuo-Qing Zhang, Bo Li, Bing-Feng Shi*. Mechanistic Studies of Rh(III)-Catalyzed C-H Olefination of Pyridines and Quinolines Promoted by Cu(OAc)2. (Published online: http://www.paper.edu.cn/releasepaper/content/201512-426)

                                                     

8. Zhen-Chao Qian, Jun Zhou, Bo Li, Bing-Feng Shi*. Rh(III)-Catalyzed Regioselective Hydroarylation of Alkynes via Directed C-H Functionalization of Pyridines. Org. Biomol. Chem.201412, 3594

                                                     

7. Zhen-Chao Qian, Jun Zhou, Bo Li, Bing-Feng Shi*. Efficient Synthesis of Isoquinolines via Rh(III)-Catalyzed Oxidative Annulation of Picolinamides with AlkynesSynlett 2014, 25, 1036

                                                    

6. Jun Zhou, Bo Li, Zhen-Chao Qian, Bing-Feng Shi*. Rh(III)-Catalyzed Oxidative Olefination of Picolinamides: Convenient Synthesis of 3-Alkenylpicolinamides. Adv. Synth. Catal, 2014356, 1038.

                                                   

5. Xiaobo Shang, Lijun Xu, Weijun Yang, Jun Zhou, Maozhong Miao, Hongjun Ren*. BF3·OEt2-Promoted Intramolecular Nucleophilic Substitution: Synthesis of Dibenzopyranones and Coumarins from Biaryltriazenes. Eur. J. Org. Chem2013, 5475

                                                     

4. Jun Zhou , Bo LiFang HuBing-Feng Shi*. Rhodium(III)-Catalyzed Oxidative Olefination of Pyridines and Quinolines: Multigram-Scale Synthesis of Naphthyridinones.  Org. Lett., 201315, 3460.

                                                     

3. Jun Zhou, Weijun Yang, Binjie Wang, Hongjun Ren*. Friedel-Crafts Arylation for the Formation of C(sp2)-C(sp2) Bond: an Efficient Route to Unsymmetrical and Functionalized Polycyclic Aromatic Hydrocarbons (PAHs) from Aryl Triazenes.  Angew. Chem. Int. Ed. 201251, 12293.

                                                       

2. Weijun Yang, Jun Zhou, Binjie Wang, Hongjun Ren*. Lewis Acid-Promoted Synthesis of Unsymmetrical and Highly Functionalized Carbazoles and Dibenzofurans from Biaryl Triazenes: Application for the Total Synthesis of Clausine C, Clausine R, and Clauraila A. Chem. Eur. J201117, 13665.

                                                                  

1. Jun Zhou, Jianjun He, Binjie Wang, Weijun Yang, Hongjun Ren*. 1,7-Palladium Migration via C-H Activation, Followed by Intramolecular Amination: Regioselective Synthesis of Benzotriazoles. J. Am. Chem. Soc2011133, 6868.  (Hilighted in Synfacts20117, 719 and Chin. J. Org. Chem., 2011, 8, 1335.)


Book Chapters:


1. Jun Zhou, Bing-Feng Shi.  Functionalization of pyridines, quinolines and isoquinolines in Transition-Metal-Catalyzed C-H Functionalization of Heterocycles.(Eds: Tharmalingam Punniyamurthy and Anil Kumar), Chapter 8, Wiley & Son, March 2023,ISBN: 978-1119774136. DOI: 10.1002/9781119774167.ch8). 


专利成果:


1. 史炳锋,周俊,李博,一种3位烯基吡啶衍生物的合成方法,中国发明专利, 申请公布号:CN103113291B  

2. 周俊,王大超,一种钯催化N-芳基苯并三氮唑衍生物的合成方法,中国发明专利,申请公布号:CN113582936A

3. 周俊,任志军,一种银介导的3,3-二取代吲哚-2-酮衍生物的合成方法,中国发明专利,申请公布号:CN114907252A

4. 周俊,甘小婷,一种氨基异喹啉多聚稠环化合物的合成方法,中国发明专利,申请公布号:CN114456111A

5. 周俊,黄芬,一种含两个季碳中心的单氯取代吲哚酮类化合物的合成方法,中国发明专利,申请号: 202211137297.7

6. 周俊,唐菁,一种银介导的异喹啉-1,3-二酮衍生物的合成方法,中国发明专利,申请号:202222506182.2