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成果及论文

47.Wei CH, Dong S, Xu Z, Li M, Zhang T, Xu Z, Lan S, Wang S, Mao L. Controllable Multi-Exciton Zero-Dimensional Antimony-Based Metal Halides for White-light Emission and β-Ray Detection. Angew Chem Int Ed Engl. 2024 Sep 11:e202412253. doi: 10.1002/anie.202412253. 

46. Jingjing Shen, Kai Feng, Jing Yu, Yaxuan Zhao, Ruifang Chen, Hehua Xiong, Yiling Ruan, Zhengtao Xu, Tao Zhang*, Xiaolian  Sun*.Responsive and Traceless Assembly of Iron Nanoparticles and 131I labeled Radiopharmaceuticals for Ferroptosis Enhanced Radio-immunotherapy. Biomaterials. 2024, doi: 10.1016/j.biomaterials.2024.122795. 

45. 周夏欢,施赛健,顾莹莹,李天女,唐立钧,张涛*.放射性药物研发的一般流程与关键点分析.中华核医学与分子影像杂志,2024, 44, 440-444.

44. German O Fonseca Cabrera, Xinrui Ma, Wilson Lin, Tao Zhang, Weiling Zhao, Liqin Pan, Xiaomei Li, Todd E Barnhart, Eduardo Aluicio-Sarduy, Huaifu Deng, Xuedan Wu, Kadalipura P Rakesh, Zibo Li, Jonathan W Engle, Zhanhong Wu*. Synthesis of 64Cu-, 55Co-, and 68Ga-Labeled Radiopharmaceuticals Targeting Neurotensin Receptor-1 for Theranostics: Adjusting In Vivo Distribution Using Multiamine Macrocycles. J Nucl Med., 2024, doi: 10.2967/jnumed.124.267469.

43. 张涛,施蒙,计欣,李天女,唐立钧,蒋建东*.零期临床助力中国原创药研发新范式迭代.中国医药生物技术,2024, 19, 193-196.

42. Tao Zhang*, Xinrui Ma, Muyun Xu, Jinghua Cai, Jianhua Cai, Yanguang Cao, Zhihao Zhang, Xin Ji, Jian He, German Oscar Fonseca Cabrera, Xuedan Wu, Weiling Zhao, Zhanhong Wu, Jin Xie*, Zibo Li*. Chelator boosted tumor-retention and pharmacokinetic properties: development of 64Cu labeled radiopharmaceuticals targeting neurotensin receptor. Eur. J. Nucl. Med. Mol. Imaging., 2024, doi: 10.1007/s00259-024-06754-2. 

41. Huihui Liu, Hehua Xiong, Changjun Li, Mengxia Xu, Yuyang Yun, Yiling Ruan, Lijun Tang, Tao Zhang*, Dan Su*, Xiaolian Sun*. 131I Induced In Vivo Proteolysis by Photoswitchable azoPROTAC Reinforces Internal Radiotherapy. Small., 2024, doi: 10.1002/smll.202310865. 

40. Xiaodan Jiao, Xiaoyang Li, Yan Du, Yiyang Cong, Shuyang Yang, Daiqin Chen, Tao Zhang*, Min Feng*, Hao Hong*. Positron emission tomography guided synergistic treatment of melanoma using multifunctional zirconium-hematoporphyrin nanosonosensitizers. J. Control. Release., 2024, 370, 95-109. 


39. Xinmiao Zhang, Jingru Guo, Ziwei Zhou, Kai Feng, Huihui Liu, Yiling Ruan, Ruifang Chen, Zixuan Liu, Tao Zhang*, Lijun Tang*,  Xiaolian Sun*. Self-Illuminating In Situ Hydrogel with Immune-Adjuvant Amplify Cerenkov Radiation-Induced Photodynamic Therapy. Chem. Biomed. Imaging.,20242, 275-282.

38. Xin Ji, Xin Chen, Kexin Li, Zhihao Zhang, Lijun Tang, Tiannv Li, Feng Han, Hao Hong*,  Tao Zhang*. Molecular Eye: A System for Precise Diagnosis and Treatment of Major Clinical Diseases Based on Molecular Probe Technology. Chem. Biomed. Imaging.,2024,2, 168–184.

37. 李政,彭灿,李希臣,董国生,韩雨霏,张涛,唐立钧*.多靶点药物的研究策略及进展.中国新药杂志, 2024, 33, 1-11.

36. 彭灿,董国生,李希臣,李政,韩雨霏,张涛*. [18F]FDOPA放射标记合成工艺研究进展中国新药杂志202433, 37-46.

35. 李希臣,李政,彭灿,钱陈,韩雨霏,张涛*.MOFs在催化有机分子转化中的应用. 化学进展202436, 367-375.

34. 唐嘉逸,华娜,许晨晨,张涛*,韩雨霏*.靶向PARP-1 PET/CT成像在肿瘤精准诊疗中应用研究进展.中国药物化学杂志,2023, 33, 948-956.

33. Huihui Liu, Qing Wang, Jingru Guo, Kai Feng, Yiling Ruan, Zhihao Zhang, Xin Ji, Jigang Wang*, Tao Zhang*, Xiaolian Sun*. Prodrug-based strategy with a two-in-one liposome for Cerenkov-induced photodynamic therapy and chemotherapy. J. Control. Release., 2023, 364, 206-215.

32.Jingru Guo, Hehua Xiong, Huihui Liu, Tao Zhang*, Xiaolian Sun*. Radioiodine based biomedical carriers for cancer theranostics. Coordin Chem Rev., 2023497, 215430.

31.董国生, 陈欣, 李可欣, 张涛*. 放射性核素偶联药物的研究进展及临床应用.药学进展. 202347, 324-336.

30.张志豪, 朱晨亿, 丛容, 张涛*. 放射性金属核素及其核医学应用. 国际医学放射学杂志. 2023, 46, 333-339; 347.

29. Xunqing Dong, Mingzhou Shang, Shuguang Chen, Tao Zhang, Hitesh B Jalani, Hongjian Lu*. Carbonyl-Assisted Iridium-Catalyzed C-H Amination Using 2,2,2-Trichloroethoxycarbonyl Azide. J. Org. Chem., 202287, 13990-14004.

 

28. Anne M Talkington, Morgan D McSweeney, Timothy Wessler, Marielle K Rath, Zibo Li, Tao Zhang, Hong Yuan, Jonathan E Frank, M Gregory Forest, Yanguang Cao, Samuel K Lai*. A PBPK model recapitulates early kinetics of anti-PEG antibody-mediated clearance of PEG-liposomes. J. Control. Release.2022, 343, 518-527.

27. Tao Zhang, Jinghua Cai, Muyun Xu, Xinrui Ma, Hui Wang, Mengzhe Wang, Zhaoguo Han, Jason Wang, Eric Smith, Zibo Li*, Zhanhong Wu*. Development of 18F-Labeled Vinyl Sulfone-PSMAi Conjugates as New PET Agents for Prostate Cancer Imaging. Mol. Pharmaceutics, 2022, 19, 720-727. (T. Zhang,  J. Cai and M. Xu contributed equally)

26. Wei Chen, Hui Wang, Nicholas E. S. Tay, Vincent A. Pistritto, Kang-Po Li, Tao Zhang, Zhanhong Wu, David A. Nicewicz,* Zibo Li*. Arene radiofluorination enabled by photoredox-mediated halide interconversion. Nat. Chem.2022, 14, 216-223.

25. Benjamin L Cline, Wen Jiang, Chaebin Lee, Zhengwei Cao, Xueyuan Yang, Shuyue Zhan, Harrison Chong, Tao Zhang, Zhaoguo Han, Xuedan Wu, Li Yao, Hui Wang, Weizhong Zhang,* Zibo Li,* Jin Xie*. Potassium Iodide Nanoparticles Enhance Radiotherapy against Breast Cancer by Exploiting the Sodium-Iodide Symporter. ACS Nano202115, 17401-17411.

24. Xiaofen Ma, Chaehin Lee, Tao Zhang, Jinghua Cai, Hui Wang, Fangchao Jiang, Zhanhong Wu, Jin Xie,* Guihua Jiang,* Zibo Li*. Image-guided selection of Gd@C-dots as sensitizers to improve radiotherapy of non-small cell lung cancer. J. Nanobiotechnol., 2021, 19, 284. (X. Ma,  C. Lee and T. Zhang contributed equally)

23. Anne M Talkington, Morgan D McSweeney, Tao Zhang, Zibo Li, Andrew C Nyborg, Brian LaMoreaux, Eric W Livingston, Jonathan E Frank, Hong Yuan, Samuel K Lai.* High MW polyethylene glycol prolongs circulation of pegloticase in mice with anti-PEG antibodies. J. Control. Release., 2021, 338, 804-812.

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22. Xinyi Zhang, Li Wang, Wenhui Fu, Yue Feng, Chengrun Zeng, Liu Zhou, Tao Zhang, Tingting Xu, Jianpeng Cao, Zibo Li,*  Yue Chen*. 18F-PEG1-Vinyl Sulfone-Labeled Red Blood Cells as Positron Emission Tomography Agent to Image Intra-Abdominal Bleeding. Front. Med., 2021, 8, 646862.

21.Chuangqi Wang, He Zhang, Tao Zhang, Xiaoyu Zou, Hui Wang, Julia Rosenbenger, Raghu Vannam, Wliiliam S. Trout, Xinqiao Jia, * Zibo Li, * Joseph M. Fox *. Enabling In Vivo Photocatalytic Activation of Rapid Bioorthogonal Chemistry by Repurposing Silicon-Rhodamine Fluorophores as Cytocompatible Far-Red Photocatalysts. J. Am. Chem. Soc., 2021, 143, 10793-10803. (C. Wang and H. Zhang contributed equally)

20. Li Wang, Hui Wang, Kun Shen, Hyejin Park, Tao Zhang, Xuedan Wu, Mei Hu, Hong Yuan, Yue Chen, Zhanhong Wu,* Qiu Wang,* Zibo Li. Development of Novel 18F-PET Agents for Tumor Hypoxia Imaging. J. Med. Chem., 2021, 64, 5593-5602.


19. Tao Zhang, Jianhua Cai, Hui Wang, Mengzhe Wang, Zhanhong Wu, Xiaofen Ma,* Zibo Li*. RXH-Reactive 18F-Vinyl Sulfones as Versatile Agents for PET Probe Construction. Bioconjugate. Chem., 2020, 31, 2482-2487. (T. Zhang and J. Cai contributed equally)

 

18. Xunqing Dong, Panpan Ma, Tao Zhang, Hitesh Jalani, Guigen Li, Hongjian Lu*, Iridium-Catalyzed C-H Amination of Weinreb Amides: A Facile Pathway towards Anilines and Quinazolin-2,4-diones, J. Org. Chem., 2020, 85, 13096-13107. (X. Dong and P. Ma contributed equally)

 

17. Mengzhe Wang, Hui Wang, Crystal Q. Niu, Tao Zhang, Zhanhong Wu, Zibo Li*, Tetrazine-TCO Ligation: A Potential Simple Approach to Improve Tumor Uptake through Enhanced Blood Circulation, Bioconjugate. Chem., 2020, 31, 1795-1803.

 

16. Xiaofen Ma, Mengzhe Wang, Hui Wang, Tao Zhang, Zhanhong Wu, Mariia V. Sutton, Vladimir V. Popik, Guihua Jiang*, Zibo Li*, Development of Bispecific NT-PSMA Heterodimer for Prostate Cancer Imaging: A Potential Approach to Address Tumor Heterogeneity, Bioconjugate. Chem., 2019, 30, 1314-1322.

 

15. Tao Zhang, Xunqing Dong, Hitesh B Jalani, Jiaqi Zou, Guigen Li, Hongjian Lu*, Iridium-Catalyzed C-H Amination/Cyclization for Medium to Large N‑Heterocycle-Fused Dihydroquinazolinones, Org. Lett., 2019, 21, 3706-3710. (T. Zhang and X. Dong contributed equally)

 

14. Tao Zhang, Xuejiao Hu, Xunqing Dong, Guigen Li, Hongjian Lu*, Iridium-Catalyzed Unreactive C(sp3)-H Amination with 2,2,2-Trichloroethoxycarbonyl Azide, Org. Lett., 2018, 20, 6260-6264.

 

13. Meng Yu, Tao Zhang, Hitesh B Jalani, Xunqing Dong, Hongjian Lu*, Guigen Li, Iridium-Catalyzed Aryl C-H Sulfonamidation and Amide Formation Using a Bifunctional Nitrogen Source, Org. Lett., 2018, 20, 4828-4832. (M. Yu and T. Zhang contributed equally)

 

12. Tao Zhang, Zhen Wang, Xuejiao Hu, Meng Yu, Tianning Deng, Guigen Li, Hongjian Lu*, Cesium Carboxylate-Promoted Iridium Catalyzed C-H Amidation/Cyclization with 2,2,2-Trichloroethoxycarbonyl Azide, J. Org. Chem., 2016, 81, 4898-4905.

 

11. Tao Zhang, Xuejiao Hu, Zhen Wang, Tiantian Yang, Hao Sun, Guigen Li, Hongjian Lu*, Carboxylate-assisted Iridium-Catalyzed C-H Amination of Arenes with Biologically Relevant Alkyl Azides. Chem. - Eur. J., 2016, 22, 2920-2924.

 

10. Tao Zhang, Zisong Qi, Xueyun Zhang, Lamei Wu, Xingwei Li*, Rh(III)-Catalyzed Hydroacylation Reactions between N-Sulfonyl 2-Aminobenzaldehydes and Olefins, Chem. - Eur. J., 2014, 20, 3283-3287. (Back Cover)

 

9. Zhiyou Li, Lamei Wu*, Tao Zhang, Zhengxi Huang, Guofu Qiu, Zhongqiang Zhou, Longfei Jin, N-2-Hydroxybenzaldehyde acylhydrazone-Fe(III) complex: Synthesis, crystal structure and its efficient and selective N-methylation. Dalton. Trans., 2014, 43, 7554-7560.

 

8. Tingting Yang, Tao Zhang, Shangdong Yang, Shanshan Chen, Xingwei Li*, Rhodium(III)-Catalyzed Coupling of N-Sulfonyl 2-Aminobenzaldehydes with Oxygenated Allylic Olefins through C-H Activation. Org. Biomol. Chem., 2014, 12, 4290-4294. (T. Yang and T. Zhang contributed equally)

 

7. Yimeng Zhang, Tao Zhang, Haoqiang Zhan and Xingwei Li*. Rh(III)-accelerated synthesis of quinoline derivates via annulation of N-Sulfonyl 2-Aminobenzaldehydes with olefins. Chin. J. Catal.2014, 35, 1840-1845. (Y. Zhang and T. Zhang contributed equally)

 

6. Tao ZhangLamei Wu*and Xingwei Li*. Rh(III)-Catalyzed Olefination of NSulfonyl Imines: Synthesis of Ortho-Olefinated Benzaldehydes. Org. Lett., 2013, 15, 6294-6297.

 

5. Xianran He, Min Zhong, Tao Zhang, Wen Wu, Zhongyuan Wu, Yuling Xiao,  Xianming Hu*, Synthesis and anticonvulsant activity of ethyl 1-(2-arylhydrazinecarboxamido)-2,2-dimethylcyclopropanecarboxylate derivatives. Eur. J. Med. Chem., 2012, 54, 542-548.

 

4. Xianran He, Min Zhong, Tao Zhang, Jin Yang, Zhongyuan Wu, Yuling Xiao, Hao Guo, Guofu Qiu, Xianming Hu*, Synthesis and anticonvulsant activity of 1-(8-(benzyloxy)quinolin-2-yl)-6-substituted-4,6-diazaspiro[2,4]heptane-5,7-diones. Eur. J. Med. Chem., 2012, 48, 338-346.

 

3. Hao Guo, Guolan Zhang, Tao Zhang, Xianran He, Zhongyuan Wu, Yuling Xiao, Yuanhu Pan, Guofu Qiu, Peng Liu, Xianming Hu*, Synthesis, characterization and biological evaluation of some 16β-azolyl-3β-amino-5α-androstane derivatives as potential anticancer agents. Eur. J. Med. Chem., 2011, 46, 3662-3674.

 

2. Jin Yang, Zhen Qu, Yuling Xiao, Guofu Qiu, Tao Zhang, Zhongyuan Wu, Xianran He, Xianming Hu*, Chemical composition and antioxidant activity of the essential oil of endemic Viola tianshanica. Natural. Product. Research., 2011, 25, 1635-1640.

 

1. Xianran He, Min Zhong, Tao Zhang, Wen Wu, Yuling Xiao, Jin Yang, Zhongyuan Wu, Yuanhu Pan, Guofu Qiu, Xianming Hu*, Synthesis and anticonvulsant activity of N-3-arylamide substituted 5,5-cyclopropanespirohydantoin derivatives. Eur. J. Med. Chem., 2010, 45, 5870-5877.