涂文玲，博士，副教授/副研究员，成都医学院第二附属医院（核工业四一六医院）辐射损伤临床救治研究中心副主任。主要从事辐射损伤、甲状腺疾病核素治疗等相关研究；主持承担了国家自然科学基金、四川省科技计划等6项科研项目，以（并列）第一/通讯作者发表SCI论文10篇，以第一发明人获2项国家发明专利和2项实用新型专利，获得中核集团等科技奖励。

【发表文章情况】（#第一作者，*通讯作者）

1. Tu W^#, Tang S^#, Yan T^#, Feng Y, Mo W, Song B, Wang J, Cheng S, Geng F, Shi Y, Yu D, Zhang S*. Integrative multi-omic analysis of radiation-induced skin injury reveals the alteration of fatty acid metabolism in early response of ionizing radiation. J Dermatol Sci. 2023: S0923-1811(23)00001-4. 

2. Tu W^#, Feng Y^#, Lai Q, Wang J, Yuan W, Yang J, Jiang S, Wu A, Cheng S, Shao J, Li J, Jiang Z, Shi Y*, Zhang S*. Metabolic Profiling Implicates a Critical Role of Cyclooxygenase-2-Mediated Arachidonic Acid Metabolism in Radiation-Induced Esophageal Injury in Rats. Radiat Res. 2022;197(5): 480-490.

3. Yao J^#, Zhang J^#, Wang J, Lai Q, Yuan W, Liu Z, Cheng S, Feng Y, Jiang Z, Shi Y, Jiang S*, Tu W*. Transcriptome Profiling Unveils a Critical Role of IL-17 Signaling-Mediated Inflammation in Radiation-Induced Esophageal Injury in Rats. Dose Response. 2022; 20(2): 15593258221104609.

4. Liu L^#, Shi Y^#, Lai Q^#, Huang Y, Jiang X, Liu Q, Huang Y, Xia Y, Xu D, Jiang Z^*, Tu W^*. Construction of a Signature Model to Predict the Radioactive Iodine Response of Papillary Thyroid Cancer. Front Endocrinol (Lausanne). 2022; 13: 865909. 

5. Xia Y^#, Jiang X^#, Huang Y^#, Liu Q, Huang Y, Zhang B, Mei Z, Xu D, Shi Y^*, Tu W^*. Construction of a Tumor Immune Microenvironment-Related Prognostic Model in BRAF-Mutated Papillary Thyroid Cancer. Front Endocrinol (Lausanne). 2022;13:895428.

6. Tu W#, Yao J#, Mei Z, Jiang X, Shi Y^*. Microarray Data of Lacrimal Gland Implicates Dysregulated Protein Processing in Endoplasmic Reticulum in Graves' Ophthalmopathy. Front Endocrinol (Lausanne). 2021;11:571151. 

7. Huang Y^#, Tu W^#, Yao Y, Cai Y, Ma L*. Construction of a Novel Gene-Based Model for Survival Prediction of Hepatitis B Virus Carriers with HCC Development. Front Genet. 2021; 12: 720888. 

8. Tu W^#, Yang B^#, Leng X, Pei X, Xu J, Liu M, Dong Q, Tao D, Lu Y, Liu Y*, Yang Y*. Testis-specific protein, Y-linked 1 activates PI3K/AKT and RAS signaling pathways through suppressing IGFBP3 expression during tumor progression. Cancer Sci. 2019; 110(5): 1573-1586.

9. Shen Y^#, Tu W^#, Liu Y, Yang X, Dong Q, Yang B, Xu J, Yan Y, Pei X, Liu M, Xu W, Yang Y*. TSPY1 suppresses USP7-mediated p53 function and promotes Spermatogonial proliferation. Cell Death Dis. 2018; 9(5):542.

10. Tu W^#, Liu Y^#, Shen Y, Yan Y, Wang X, Yang D, Li L, Ma Y, Tao D, Zhang S, Yang Y*. Genome-wide Loci linked to non-obstructive azoospermia susceptibility may Be independent of reduced sperm production in males with normozoospermia. Biol Reprod. 2015; 92(2): 41.

【专利申请情况】

1. “一种基于单样本学习的细胞分布模型构建及细胞计数方法”，发明人：涂文玲；史育红；蒋胜；冯亚辉；张舒羽；江雪；专利号：ZL 202110109382.1，中国发明专利。

2. “一种实验鼠数据采集装置及采集方法”，发明人：涂文玲；张舒羽；蒋胜；冯亚辉；江雪；史育红；专利号：ZL 202110078919.2，中国发明专利。

3. “一种细胞培养抗辐射模具”，发明人：涂文玲；张舒羽；史育红；李静怡；邵继春；专利号：ZL 2020 2 0274342.3，中国实用新型专利。

4. “一种抗体孵育装置”，发明人：涂文玲；张舒羽；史育红；李静怡；邵继春；蒋胜；专利号：ZL 2020 2 0310168.3，中国实用新型专利。

5. “一种动物模型放射性食管损伤照射装置”，发明人：张舒羽；涂文玲；蒋胜；李静怡；刘锐；专利号：ZL 2020 2 0469762.7，中国实用新型专利。