11325
当前位置: 首页   >  成果及论文
成果及论文

代表性期刊论文

1.Huiying Chen, Xuefeng Fan, Yinan Zhao, Defu Zhi, Shaohui Cui, Enxia Zhang, Haoming Lan, Jianjun Du, Zhen Zhang, Shubiao Zhang*, Yuhong Zhen*. Stimuli-Responsive Polysaccharide Enveloped Liposome for Targeting and Penetrating Delivery of survivin-shRNA into Breast Tumor. ACS Appl. Mater. Interfaces 2020, 12, 22074−22087.

2.Defu Zhi, Ting Yang, Jian Yang, Shuang Fu, Shubiao Zhang*. Targeting strategies for superparamagnetic iron oxide nanoparticles in cancer therapy. Acta Biomaterialia, 2020, 102: 13–34.

3.Yinan Zhao, Yingnan Cao, Jiao Sun, Ze Liang, Qiong Wu, Shaohui Cui, Defu Zhi, Shutao Guo, Yuhong Zhen, Shubiao Zhang*. Anti-breast cancer activity of resveratrol encapsulated in liposomes. Journal of Materials Chemistry B, 2020, 8(1): 27-37.

4.Chuanmin Zhang, Shubiao Zhang*, Defu Zhi, Yinan Zhao Shaohui Cui, Jingnan Cui. Co-delivery of paclitaxel and survivin siRNA with cationic liposome for lung cancer therapy. Colloids and Surfaces A, 2020, 585:1-9.

5.Qinqin Gao, Chuanmin Zhang, Enxia Zhang, Huiying Chen, Yuhong Zhen, Shubiao Zhang*, Shu-Fen Zhang. Zwitterionic pH-responsive hyaluronic acid polymer micelles for delivery of doxorubicin. Colloids and Surfaces B: Biointerfaces 178 (2019) 412–420. 

6.Yanyan Zhu, Yao Meng, Yinan Zhao, Jie Zhu, Hong Xu, Enxia Zhang, Lei Shi, Linying Du, Guoliang Liu, Chuanmin Zhang, Xiaodong Xu, Xiaohui Kang, Yuhong Zhen, Shubiao Zhang*. Toxicological exploration of peptide-based cationic liposomes in siRNA delivery. Colloids and Surfaces B: Biointerfaces, 2019, 179: 66-76.

7.Enxia Zhang, Jiasi Liu, Lei Shi, Xin Guo, Ze Liang, Jiaxin Zuo, Hong Xu, Huaxin Wang, Xiaohong Shu, Shanshan Huang, Shubiao Zhang, Xiaohui Kang, Yuhong Zhen. 7-O-geranylquercetin contributes to reverse P-gp-mediated adriamycin resistance in breast cancer. Life Sciences, 2019, 238:1-9.

8.Meilin Jiang, Enxia Zhang, Ze Liang, Yinan Zhao, Shubiao Zhang, Hong Xu, Huaxin Wang, Xiaohong Shu, Xiaohui Kang, Lidan Sun, Yuhong Zhen. Liposome-based co-delivery of 7-O-geranyl-quercetin and IGF-1R siRNA for the synergistic treatment of non-small cell lung cancer. Journal of Drug Delivery Science and Technology, 2019, 54:1-8.

9.Jiaxin Zuo, Yameng Jiang, Enxia Zhang, Yuling Chen, Ze Liang, Jie Zhu, Yinan Zhao, Hong Xu, Guoliang Liu, Jiasi Liu, Wei Wang, Shubiao Zhang*, Yuhong Zhen. Synergistic effffects of 7-O-geranylquercetin and siRNAs on the treatment of human breast cancer. Life Sciences, 2019, 227: 145–152.

10.Shuang Fu, Xiaodong Xu, Yu Ma, Shubiao Zhang*,& Shufen Zhang. RGD Peptide Based Non-viral Gene Delivery Vectors Targeting Integrin αvβ3 for Cancer Therapy. Journal of drug targeting, 2019, 27(1): 1-11.

11.Xiaodong Xu, An Liu, Yuchao Bai, Yinan Li, Chuanmin Zhang, Shaohui Cui, Yongzhe Piao, Shubiao Zhang*. Co-delivery of resveratrol and p53 gene via peptide cationic liposomal nanocarrier for the synergistic treatment of cervical cancer and breast cancer cells. Journal of Drug Delivery Science & Technology, 2019, 51: 746-753.

12.Chuanmin Zhang, Shubiao Zhang*, Defu Zhi, Jiangnan Cui. Cancer treatment with liposomes based drugs and genes co-delivery systems. Current Medicinal Chemistry, 2018, 25(28):3319-3332.

13.Hengjun Zhou, Jian Yang, Yanyan Du, Shuang Fu, Chenxi Song, Defu Zhi, Yinan Zhao, Huiying Chen, Shubiao Zhang*, Shufen Zhang. Novel carbamate-linked quaternary ammonium lipids containingunsaturated hydrophobic chains for gene delivery. Bioorganic & medicinal chemistry, 2018, 26(12): 3535-3540.

14.Shaohui Cui, Yueying Wang, Yan Gong, Xiao Lin, Yinan Zhao, Defu Zhi, Quan Zhou, Shubiao Zhang*. Correlation of cytotoxic effects of cationic lipids with their headgroups. Toxicology Research, 2018, 7(3): 473-479.

15.Huiying Chen, Yu Ma, Haoming Lan, Yinan Zhao, Defu Zhi, Shaohui Cui, Jianjun Du, Zhen Zhang, Yuhong Zhen*, Shubiao Zhang*. Dual stimuli-responsive saccharide core based nanocarrier for efficient Birc5-shRNA delivery. Journal of Materials Chemistry B, 2018, 6(45): 7530-7542.

16.Defu Zhi, Yuchao Bai, Jian Yang, Shaohui Cui, Yinan Zhao, Huiying Chen, Shubiao Zhang*. A review on cationic lipids with different linkers for gene delivery[J]. Advances in colloid and interface science, 2018, 253: 117-140.

17.Haiping Zhong, Jingqing Mu, Yanyan Du, Zunkai Xu, Yang Xu, Na Yu, Shubiao Zhang*, Shutao Guo. Acid-triggered release of native gemcitabine conjugated in polyketal nanoparticles for enhanced anticancer therapy. Biomacromolecules 2020, 21: 803-814. Yinan Zhao, An Liu, Yanyan Du, Yingnan Cao, Enxia Zhang, Quan Zhou, Hua Hai, Yuhong Zhen, Shubiao Zhang*. Effects of Sucrose Ester Structures on Liposome-Mediated Gene Delivery. Acta Biomaterialia 2018, (72): 278-286.

18.Yinan Zhao, Yongzhe Piao, Chuanmin Zhang, Yameng Jiang, An Liu, Shaohui Cui, Defu Zhi, Yuhong Zhen, Shubiao Zhang*. Replacement of quaternary ammonium headgroup by tri-ornithine in cationic lipid for the improvement of gene delivery in vitro and in vivo[J]. Journal of Materials Chemistry B 2017, 5(39): 7963-7973.

19.Chenxi Song, Shubiao Zhang*, Quan Zhou, Lei Shi, Linying Du, Defu Zhi, Yinan Zhao, Yuhong Zhenc, Defeng Zhao*. Bifunctional cationic solid lipid nanoparticles of β-NaYF4:Yb,Er upconversion nanoparticles coated with a lipid for bioimaging and gene delivery. Rsc Advances, 2017, 7(43):26633-26639.

20.Chenxi Song, Shubiao Zhang*, Quan Zhou, Hua Hai, Defeng Zhao, Yunze Hui. Upconversion nanoparticles for bioimaging. Nanotechnology Reviews, 2016, 6(2): 233-242.

21.Shaohui Cui, Defu Zhi, Yinan Zhao, Huiying Chen, Yao Meng, Chuimin Zhang, Shubiao Zhang*.Cationic lioposomes with folic                    acid as targeting ligand for gene delivery. Bioorganic & Medicinal Chemistry Letters, 2016, 26(16):4025.

22.Defu Zhi, Yinan Zhao, Shaohui Cui, Huiying Chen, Shubiao Zhang*. Conjugates of small targeting molecules to non-viral vectors for the mediation of siRNA. Acta Biomaterialia, 2016, 36:21-41. 

23.Jia Shi, Shijun Yu, Jie Zhu, Defu Zhi, Yinan Zhao, Shaohui Cui, Shuabiao Zhang*.Carbamate-linked cationic lipids with different hydrocarbon chains for gene delivery. Colloids & Surfaces B Biointerfaces, 2016, 141:417-422.

24.Yinan Zhao, Jie Zhu, Hengjun Zhou, Xin Guo, Tian Tian, Shaohui Cui, Yuhong Zhen, Shubiao Zhang*, Yuhong Xu. Sucrose ester based cationic liposomes as effective non-viral gene vectors for gene delivery. Colloids & Surfaces B Biointerfaces, 2016, 145:454-461.

25.Yinan zhao, Shubiao Zhang*, Yuan Zhang, Shaohui Cui, Huiying Chen, Defu Zhi, Yuhong Zhen, Shufen zhang, Leaf Huang. Tri-peptide cationic lipids for gene delivery, J. Mater. Chem. B, 2015, 3: 119-126.

专著

Yinan Zhao, Defu Zhi, Shubiao Zhang (2011), Cationic liposomes in different structural levels for gene delivery, NON-VIRAL GENE THERAPY, InTech, 

专利   

1.Shubiao Zhang, Yinan Zhao, Shaohui Cui, huiying Chen, Quan Zhou. Bisalkoxyl amide alkyl cationic peptide lipids, synthesis method thereof, and application thereof, US10597678B2, 2020.3. 美国发明专利

2.Shubiao Zhang, Yinan Zhao, Shaohui Cui, Defu Zhi, Hua Hai. Propyl cationic peptide lipids,synthesis method thereof, and application thereof, US10294199B2, 2019.5. 美国发明专利

3.Shubiao Zhang, Defu Zhi, Shaohui Cui, Yinan Zhao, Quan Zhou. Sucrose ester-type cationic gene vector and preparation method thereof, US10279050B2, 2019.5. 美国发明专利

4.张树彪,陈会英,马羽,秦晓利,蓝浩铭,崔韶晖. 双脂肪链取代基磷脂酰乙醇胺壳聚糖的应用, ZL201711363440.3, 2019.11. 中国发明专利

5.张树彪, 陈会英, 马羽, 秦晓利, 蓝浩铭, 崔韶晖. 氧化还原响应壳聚糖-脂质体的制备方法和用途, ZL201710620705.7, 2019.07. 中国发明专利

6.张树彪, 陈会英, 马羽, 秦晓利, 蓝浩铭, 崔韶晖. 双脂肪链取代基磷脂酰乙醇胺壳聚糖及其制备方法和用途, ZL201710620704.2, 2019.06. 中国发明专利

7.张树彪, 赵轶男, 崔诗慧, 赫泽坤, 徐宇虹. 蔗糖脂肪酸酯嵌入式阳离子脂质体基因载体系统及其制备方法和应用, ZL201511011257.8, 2019.01. 中国发明专利

8.张树彪,陈会英,赵轶男,支德福. pH响应壳聚糖基因载体及其制备方法和应用, ZL201610486542.3, 2018.02. 中国发明专利

9.张树彪,陈会英,崔韶晖,海华. 微环境双重响应壳聚糖基因载体及其制备方法和应用, ZL201610482178.3, 2018.11. 中国发明专利

10.张树彪, 陈会英, 赵轶男, 支德福. pH响应壳聚糖基因载体及其制备方法和应用, ZL201610486542.3, 2018.12. 中国发明专利

11.张树彪, 陈会英, 崔韶晖, 海华. 微环境双重响应壳聚糖基因载体及其制备方法和应用, ZL201610482178.3, 2018.12. 中国发明专利

12.张树彪, 支德福, 崔韶晖, 赵轶男, 周泉. 一类蔗糖酯型阳离子基因载体及其制备方法, ZL201510071065.X, 2018.6. 中国发明专利

13.张树彪, 陈会英, 赵轶男, 崔韶晖, 王冰. O-烷基氨基甲酸酯壳聚糖、转基因复合物微粒及其制备方法, ZL201410164063.0, 2016.6. 中国发明专利

14.张树彪, 陈会英, 崔韶晖, 赵轶男. 一种洁净制备壳聚糖接枝聚乙烯亚胺非病毒基因载体的方法,ZL201410043960.6,2016.6. 中国发明专利

奖励

张树彪, 崔韶晖, 赵轶男, 陈会英, 支德福. 新型氨基甲酸酯基因载体的设计合成与制备方法. 辽宁省技术发明三等奖, 2014.11.