个人简介：

高偲嘉

2020年5月-至今 天津工业大学 张拥军教授团队

2014年9月-2020年1月 中国科学院大学 高分子化学与物理专业 理学博士

2010年9月-2014年6月 北京化工大学 高分子材料与工程专业 工学学士

主要研究方向：

1.蛋白印迹聚合物的设计及其在生物医用领域的应用

2.苯硼酸基葡萄糖敏感材料及其在可自我调节胰岛素释放的应用

3.蛋白质自组装及其在药物递送领域的应用

联系方式：

E-mail: gaosijia@tiangong.edu.cn;    Tel. No.:155-2289-1068

代表性学术论文：

1. Gao, Sijia^#; Yan, Xuzhou^#*; Xie, Guocheng; Zhu, Meng; Ju, Xiaoyan; Stang, Peter J.^*; Tian, Ye^*; Niu, Zhongwei; Membrane intercalation-enhanced photodynamic inactivation of bacteria by a metallacycle and TAT-decorated virus coat protein, Proceedings of the National Academy of Sciences of the United States of America, 2019, 116(47): 23437-23443.
2. Gao, Sijia; Liu, Xiangxiang; Wang, Zhaocheng; Jiang, Shidong; Wu, Man; Tian, Ye^*; Niu, Zhongwei^*; Fluorous interaction induced self-assembly of tobacco mosaic virus coat protein for cisplatin delivery, Nanoscale, 2018, 10 (25): 11732-11736.
3. Gao, Sijia; Li, Zhuang; Sun, Zhicheng; Wen, Jinyue; Li, Furong; Du, Xiaoyang; Liu, Yan; Tian, Ye^*; Niu, Zhongwei^*; Single-wavelength excited ratiometric fluorescence pH probe to image intracellular trafficking of tobacco mosaic virus, Chinese Journal of Polymer Science, 2020, 38(6): 587-592.

4. Huang, Di^#; Gao, Sijia^#,*; Luo, Ying; Zhou, Xiaoman; Lu, Zhengbo; Zou, Lei; Hu, Keling; Zhuo Zhao; Zhang, Yongjun*, Glucose-sensitive membrane with phenylboronic acid-based contraction-type microgels as chemical valves, Journal of Membrane Science, 2022, 650, 120406.

5. Liu, Jing; Gao, Sijia*, Luo, Ying; Zhang, Chunpeng; Zhang, Pengliang; Wang, Zilin; Zou, Lei; Zhao, Zhuo; Zhang, Yongjun*, Glucose-sensitive poly(ether sulfone) composite membranes blended with phenyboronic acid-based amphiphilic block copolymer for self-regulated insulin release, Journal of Materials Chemistry B, 2023, 11, 5000.
   

6. Zhang, Chunpeng; Gao Sijia*; Luo, Ying; Zou, Lei; Zhang, Yongjun*, Glucose-sensitive membrane with PBA-based contraction-type linear polymer as chemical valves prepared by surface grafting, Chinese Journal of Polymer Science, DOI: 10.1007/s10118-024-3135-3.

7. Xie, Guocheng; Gao, Sijia; Ou, Jinzhao; Zhu, Meng; Wu, Man; Ju, Xiaoyan; Li, Zhuang; Tian, Ye^*; Niu, Zhongwei^*; Conjugating peptides onto 1D rodlike bionanoparticles for enhanced activity against gram-negative bacteria, Nano Letters, 2021, 21(4): 1722-1728.
8. Wang, Zhaocheng; Gao, Sijia; Liu, Xiangxiang; Tian, Ye^*; Wu, Man; Niu, Zhongwei^*; Programming self-assembly of tobacco mosaic virus coat proteins at pickering emulsion interfaces for nanorod-constructed capsules, ACS Applied Materials & Interfaces, 2017, 9(33): 27383-27389.
9. Tian, Ye; Gao, Sijia; Wu, Man; Liu, Xiangxiang; Qiao, Jing; Zhou, Quan; Jiang, Shidong; Niu, Zhongwei^*; Tobacco mosaic virus-based 1D nanorod-drug carrier via the integrin-mediated endocytosis pathway, ACS Applied Materials & Interfaces, 2016, 8(17), 10800-10807.
10. Liu, Xiangxiang; Liu, Bowei; Gao, Sijia; Wang, Zhaocheng; Tian, Ye^*, Wu, Man; Jiang, Shidong; Niu, Zhongwei*; Glyco-decorated tobacco mosaic virus as a vector for cisplatin delivery, Journal of Materials Chemistry B, 2017, 5, 2078-2085.
11. Tian, Ye; Zhou, Mengxue; Shi, Haigang; Gao, Sijia; Xie, Guocheng; Zhu, Meng; Wu, Man; Chen, Jun; Niu, Zhongwei^*; Integration of cell-penetrating peptides with rod-like bionanoparticles: Virus-inspired gene-silencing technology, Nano Letters, 2018, 18(9), 5453-5460.
12. Ju, Xiaoyan; Chen, Jun; Zhou, Mengxue; Zhu, Meng; Li, Zhuang; Gao, Sijia; Ou, Jinzhao; Xu, Dandan; Wu, Man; Jiang, Shidong; Hu, Yi; Tian, Ye^*; Niu, Zhongwei^*; Combating pseudomonas aeruginosa biofilms by a chitosan-PEG-peptide conjugate via changes in assembled structure, ACS Applied Materials & Interfaces, 2020, 12(12), 13731-13738.

代表性专利：

1. 牛忠伟, 高偲嘉, 田野 一种蛋白质组装体及其制备方法 授权公告号：CN 108640980 B
2. 牛忠伟, 高偲嘉, 田野 一种纳米粒子及其在制备灭活细菌的光动力制剂中的应用 授权公告号：CN 110075089 B
3. 牛忠伟, 田野, 高偲嘉 一种噬菌体及其在制备灭活细菌的光动力制剂中的应用 授权公告号：CN 110151994 B