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成果及论文


【2024年】:


(42) Pengfei Zhou, Xingchi Li, Cheng Wang, Guibin Wan, Zhuan Zhang.* Regiodivergent C–H  Functionalization of Heterocycles.  ACS Fall 2024https://doi.org/10.1021/scimeetings.5c10975. 


(41) Yuting Gui, Yaokun Zhao, Xingchi Li, Taoyuan Liang, Shuangliang Zhao,* Zhuan Zhang.* Catalyst-ontrolled Regiodivergent C–H Alkynylation of 2-Pyridylthiophenes. Adv. Synth. Catal. 2024, 366, 1–8. DOI: 10.1002/adsc.202400856. 


(40) Maoyi Dai, Meilan Xu, Xiaoting Gu, Pengyan Zhang, Yukun Xie, Jin Zhuge, Xinting Liang, Runmin Liao, Zongwu Wei, Zhuan Zhang, and Taoyuan Liang,* Iron-catalyzed C−H arylphosphorylation of quinoxalines. Org. Lett202426, 7672–7677. DOI: 10.1021/acs.orglett.4c02791.


(39) Yaokun Zhao, Xingchi Li, Pengfei Zhou, Xing Han, Chenjie Zhang, Taoyuan Liang, Shuangliang Zhao,* Zhuan Zhang,* Rh-Catalyzed C–H Alkynylation of Indole Derivatives with Silver(I)-Controlled Regiodivergence. Org. Lett202426, 7285–7290. DOI: 10.1021/acs.orglett.4c02151.


(38) Pengfei Zhou, Cheng Wang, Guibin Wan,. Weining Zheng, Zongwu Wei, Taoyuan Liang, Jun Jiang,* Zhuan Zhang,* Regiodivergent Metal-Catalyzed Oxidative Alkynylation of 2-Arylthiazoles with Terminal Alkynes under Air Conditions. J. Org. Chem202489, 10953–10964. DOI: 10.1021/acs.joc.4c01381.


(37) Xiaoting Gu, Maoyi Dai, Xirui Qing, Yifeng Liu, Zhuan Zhang, Zongwu Wei,* Taoyuan Liang,* Iron-Catalyzed Friedel-Crafts-Type 3,5-Diacylation of Indoles. J. Org. Chem2024, 89, 10272–10282. DOI: 10.1021/acs.joc.4c01157.


(36) Pengfei Zhou,‡ Xinyao Liang,‡ Zekun Xu, Honggu Chen, Zongwu Wei, Taoyuan Liang, Jun Jiang* and  Zhuan Zhang* Regiodivergent C–H alkynylation of 2-arylthiazoles switched by RuII and PdII catalysis.  Chem. Commun., 202460, 66796682. DOI: 10.1039/D4CC02254H.


(35) Yingying Zhang, Xiaoxiang Zhang, Junqiu Liao, Zongwu Wei, Zhuan Zhang, Taoyuan Liang* Organoselenium-catalyzed C2,3-diarylation of N−H indoles. J. Org. Chem202489, 7216–7224. DOI: 10.1021/acs.joc.4c00622.


(34) Yifeng Liu, Xiaoting Gu, Xiaoxiang Zhang, Meilan Xu, Zhuan Zhang and Taoyuan Liang* Iodine–Mediated Oxidative Triple Functionalization of Indolines with Azoles and Diazonium Salts. Chem. Commun., 2024 60, 46134616. DOI: 10.1039/D4CC00856A.


(33) Zhuan Zhang, Taoyuan Liang. Green Solvents in Organic Synthesis [BOOK] (Pages: 199-236). WILEY-VCH GmbH, Weinheim, Germany. 2024. Print ISBN: 9783527352005, Online ISBN: 9783527841943, DOI: 10.1002/9783527841943.


(32) Xiaoxiang Zhang, Xiaoting Gu, Yingying Zhang, Junqiu Liao, Meilan Xu, Zhuan Zhang and Taoyuan Liang* Solvent-Controlled Switchable Multicomponent Tandem Oxidative Triple Functionalization of Indolines. Org. Chem. Front., 202411, 19331940. DOI: 10.1039/D4QO00030G. 


(31) Xiaoxiang Zhang, Chenrui Liu, Wanxing Wei, Zhuan Zhang and Taoyuan Liang* Iodine-Dependent Oxidative Regioselective Aminochalcogenation of Indolines. Chem. Commun., 2024, 60, 1152–1155. DOI: 10.1039/D3CC05999E.


(30) Xiaoxiang Zhang, Chenrui Liu, Wenwei Pang, Xiaoting Gu, Wanxing Wei, Zhuan Zhang, Haiyan Chen and Taoyuan Liang,* Directing-group-free Strategy for the Iodine-mediated Regioselective Dichalcogenation of Indolines: Understanding the Full Catalytic Cycles. Org. Chem. Front. 202411, 871884. DOI: 10.1039/D3QO01492D.


【2023年】:


(29) Xiaoxiang Zhang,‡ Chenrui Liu,‡ Yingying Zhang, Fang Shen, Wanxing Wei, Zhuan Zhang and Taoyuan Liang* Organo-catalyzed C2,3−H Aminochalcogenation of Indoles with Secondary (Aliphatic) Amines. Org. Chem. Front202310, 58865894. DOI: 10.1039/D3QO01457F. 


(28) Maoyi Dai, Yingying Zhang, Xiaoxiang Zhang, Ruiyi Wang, Wanxing Wei, Zhuan Zhang, Taoyuan Liang* Iodine-mediated C2,3−H aminoheteroarylation of indoles. J. Org. Chem2023, 88, 15106–15117. DOI: 10.1021/acs.joc.3c01591.


(27) Xuecong Huang, Pengfei Zhou, Xingdong Yang, Ruiyi Wang, Guan Huang, Taoyuan Liang, Zhuan Zhang* Catalyst-Controlled Divergent C3/C5 Site-Selective C−H Arylation of 2-Pyridylthiophenes. Adv. Synth. Catal. 2023, 365, 36743679. DOI: 10.1002/adsc.202300724. 


(26) Wenhua Yu,‡ Yingying Zhang,‡ Xiaoxiang Zhang, Xiaoting Gu, Xirui Qing, Wanxing Wei, Zhuan Zhang, Guanghua Li,* Taoyuan Liang* Synthesis of 2,3-Diaminoindoles via a Copper-iodine Co-catalytic Strategy. Chin. J. Chem. 202341, 3567–3572. DOI: 10.1002/cjoc.202300470.


(25) Fengqi Yang, Pengfei Zhou, Zeng Huang, Junqiu Liao, Guan Huang, Taoyuan Liang, and Zhuan Zhang* Ruthenium(II)-Catalyzed Remote C–H Sulfonylation of 2-Pyridones. Org. Lett202325, 5779–5783. DOI: 10.1021/acs.orglett.3c02004. (Highlighted  by CBG, https://mp.weixin.qq.com/s?__biz=MzI4ODQ0NjUwMg==&mid=2247620091&idx=2&sn=7f782172703b92626c63c2aaf40188a0&chksm=ed18780c0780970c77c5125b41d35d6f3ea8b66c2a66402870f4d42287d4b2c36a21228b91c6&mpshare=1&scene=23&srcid=0819O8Cjeh9IvN1lddVyuuTD&sharer_shareinfo=f5039d2cdce6d4d9a779fa68e065e7fe&sharer_shareinfo_first=f5039d2cdce6d4d9a779fa68e065e7fe#rd; https://www.163.com/dy/article/ICGEQO3M0518U16R.html)


(24) Qiang Zhang,‡   Pengfei Zhou,‡   Yaokun Zhao,   Yeran Liu,   Taoyuan Liang,  Jun Jiang*  and  Zhuan Zhang* Catalyst-controlled regiodivergent C–H bond alkenylation of 2-pyridylthiophenes. Chem. Commun., 202359, 88428845. DOI: 10.1039/D3CC02411C.

                                               



(23) Xiaoting Gu.§ Xiaoxiang Zhang,§ Wenhua Yu, Ke Sun, Wanxing Wei, Zhuan Zhang, and Taoyuan Liang,* Multicomponent Tandem Triple Functionalization of Indoles via a Directing-group-free Strategy. Adv. Synth. Catal. 2023365, 990996. DOI: 10.1002/adsc.202300208. 


(22) Qiang Zhang, Xuecong Huang, Yuting Gui, Youyuan He, Siyang Liao, Guan Huang, Taoyuan Liang, and Zhuan Zhang,* Unlocking Regiodivergence in PdII- and RhIII-Mediated Site-Selective C–H Bond Alkynylation of Imidazopyridines. Org. Lett. 202325, 1447–1452. DOI: 10.1021/acs.orglett.3c00178.


(21) Xiaoxiang Zhang, Chenrui Liu, Wenwei Pang, Xiaoting Gu, Wanxing Wei,  Zhuan Zhang, HaiyanChen* and Taoyuan Liang,* Directing-group-free strategy for the iodine-mediated regioselective dichalcogenation of indolines: understanding the full catalytic cycles. Org. Chem. Front., 2024, 11, 871–884. DOI: 10.1039/d3qo01492d.


【2022年】


(20) Yingying Zhang, Yating Huang, Kewei Yu, Xiaoxiang Zhang, Wenhua Yu, Jiale Tang, Yiran Tian, Wanxing Wei, Zhuan  Zhang,* and Taoyuan Liang*. Iron-iodine co-catalysis towards tandem C−N/C−C bond formation: one-pot regioselective synthesis of 2-amino-3-alkylindoles. Org. Chem. Front. 20229, 61656171. DOI: 10.1039/D2QO01329K. (Highlighted by Frontiers Journalshttps://mp.weixin.qq.com/s/KIK3R-eoV10xuicSRl1sNA.)

(19) Zhuan Zhang, Natacha Durand, Jean-François SouléHow Rh(I)-Catalyzed P(III)-Directed C–H Bond functionalizations Could Improve the Phosphines Catalytic Activities.  Synlett2022, 33, 705-712. DOI:10.1055/s-0041-1737325.

(18) Javid Rzayev, Zhuan Zhang, Natacha Durand, and Jean-Francois Soulé*. Upgrading Carbazolyl-Derived Phosphine Ligands Using RhICatalyzed PIII-Directed CH Bond Alkylation for Catalytic CO2Fixation Reactions.Org. Lett. 2022, 24, 67556760. DOI: 10.1021/acs.orglett.2c02514.


(17) Yuanhui Lu, Xiaoxiang Zhang, Xiaoyu Xiao, Ninghua Huang, Yadong Dou, Chenrui Liu, Wanxing Wei, Zhuan Zhang, and Taoyuan Liang*. Copper-mediated intermolecular C−H aminohalogenation of indoles at room temperature. Asian J. Org. Chem. 202211, e202200457.  DOI: 10.1002/ajoc.202200457.


(16) Wenhua Yu, Xiaoxiang Zhang, Chenrui Liu, Yingying Zhang, Xiaoting Gu, Jiahao Liao, Zhuan  Zhang, Wanxing Wei,* Guanghua Li,* and Taoyuan Liang*. Intermolecular C−H aminocyanation of indoles via copper-iodine co-catalyzed tandem C−N/C−C bond formation. J. Org. Chem. 202287, 12424–12433.  DOI: 10.1021/acs.joc.2c01703. 


(15) Yuanhui Lu,‡ Tianxiang Chen,‡ Xiaoyu Xiao, Ninghua Huang, Yadong Dou, Wanxing Wei, Zhuan Zhang, Benedict Tsz Woon Lo* and Taoyuan Liang*. Copper dual-atom catalyst mediated C3−H amination of indoles at room temperature. Catal. Sci. Technol., 202212, 53905396. DOI: 10.1039/D2CY01126C. 

(14) Xiaoxiang Zhang, Wenhua Yu, Yiyu Nie, Yingying Zhang, Xiaoting Gu, Wanxing Wei, Zhuan Zhang,and Taoyuan Liang*. Copper-iodine Co-catalyzed C−H Aminoalkenylation of Indoles via Temperature-Controlled Selectivity Switch: Facile Synthesis of 2-Azolyl-3-alkenylindoles. Org. Chem. Front. 2022, 9, 37943799. DOI: 10.1039/D2QO00627H. 

【2021年】

(13) Xiaoxiang Zhang, Yingying Zhang, Xiaoting Gu, Zhuan Zhang, Wanxing Wei* and Taoyuan Liang*. Synthesis of 3-Halogenated 2,3′-Biindoles by a Copper-mediated 2,3-Difunctionalization of Indoles. Org. Biomol. Chem. 202119, 10403–10407. DOI: 10.1039/D1OB02024B.


【2020年】

(12) Zhuan Zhang, Marie Cordier, Pierre H. Dixneuf, and Jean-Francois Soule*. Late-Stage Diversification of Biarylphosphines through Rhodium(I)-Catalyzed CH Bond Alkenylation with Internal AlkynesOrg. Lett. 2020, 22, 59365940. DOI: 10.1021/acs.orglett.0c02023.


【2019年】


(11) Yang Chen, Zhuan Zhang, Wei Jiang, Mingjuan Zhang , Yiqun Li. RuIII@CMC/Fe3O4 hybrid: an efficient, magnetic, retrievable, self-organized nanocatalyst for green synthesis of pyranopyrazole and polyhydroquinoline derivatives Mol. Divers. , 2019, 23, 421–442. DOI: 10.1007/s1103001898873.



(10) Zhuan Zhang, Thierry Roisnel, Pierre H. Dixneuf, and Jean-François Soulé*. RhI-Catalyzed PIII-Directed CH Bond Alkylation: Design of Multifunctional Phosphines for Carboxylation of Aryl Bromides with Carbon Dioxide. Angew. Chem. Int. Ed. , 201958, 14110–14114. DOI: 10.1002/ange.201906913.



(9) Zhiping Yin, Zhuan Zhang, Youcan Zhang, Pierre H. Dixneuf  and Xiao-Feng Wu*. Carbonylation of tertiary carbon radicals: synthesis of lactams. Chem. Commun., 201955, 46554658. DOI: 10.1039/c9cc02112d.




(8) Zhiping Yin,‡ Zhuan Zhang,‡ Jean-François Soulé, Pierre H. Dixneuf, Xiao-Feng Wu*. Iron-catalyzed carbonylative alkyl-acylation of heteroarenesJ. Catal., 2019, 372, 272–276DOI: 10.1016/jcat.201903001.



【2018年】

(7) Zhuan Zhang, Pierre H. Dixneuf * and Jean-François Soule*. Late stage modifications of P-containing ligands using transition-metal-catalysed C–H bond functionalisation.Chem. Commun., 2018, 54, 7265--7280. DOI: 10.1039/c8cc02821d



【2017年】


(6) Yizong Zhang, Zhuan Zhang, Yang Chen, Yiqun Li*. Copper (II) immobilized on aminated poly(vinyl chloride) as an efficient and retrievable catalyst for the CuAAC reaction in water under mild conditions.Res Chem Intermed 2017, 43, 7307–7318. DOI: 10.1007/s11164-017-3076-3.


(5) Zhuan Zhang, Yizong Zhang, Xiaoping Liu, Binbin Shen, Tianzhu Zhang, Yiqun Li*. Assembly immobilized palladium(0) on carboxymethylcellulose/Fe3O4 hybrid: An efficient tailormade magnetically catalyst for the SuzukiMiyaura couplingsAppl Organometal Chem. 201832, e3912.  DOI: 10.1002/aoc.3912.


(4) Bijin Lin, Xiaoping Liu, Zhuan Zhang, Yang Chen, Xiaojian Liao* , Yiqun Li*. Pd(0)–CMC@Ce(OH)organic/inorganic hybrid as highly active catalyst for the Suzuki–Miyaura reactionJ Colloid Interf Sci  2017, 497, 134–143.DOI: 10.1016/jcis.201702066.


(3) Junbin Zhou, Xingtian Huang, Zhuan Zhang, Ping Song, Yiqun Li*. Trypsin-catalyzed multicomponent reaction: A novel and efficient one-pot synthesis of thiazole-2-imine derivativesJ. Biotechnol. 2017241, 14–21. DOI:  10.1016/jbiotec.201611004.


【2016年】


(2) Xiaoping Liu, Bijin Lin, Zhuan Zhang, Hao Lei and Yiqun Li *. Copper(II) carboxymethylcellulose (CMC-CuII) as an efficient catalyst for aldehyde–alkyne–amine coupling under solvent-free conditions.RSC Adv., 2016, 6, 94399–94407. DOI: 10.1039/c6ra18742k.


(1) Zhuan Zhang, Ping Song, Junbin Zhou, Yang Chen, Bijin Lin, and Yiqun Li*. Metathesis Strategy for the Immobilization of Copper(II) onto Carboxymethylcellulose/Fe3O4 Nanohybrid Supports: Efficient and Recoverable Magnetic Catalyst for the CuAAC Reaction.Ind. Eng. Chem. Res., 2016, 55, 12301−12308. DOI: 10.1021/acs.iecr.6b03158.



【发明专利】:

[1] 张专,刘烨然,黄学聪,廖俊秋,王睿逸,卿曦蕊,三取代烯烃咔唑膦配体衍生物的合成方法,CN202310592972.3.



【著作】:

[1] Zhuan Zhang, Taoyuan Liang. Green Solvents in Organic Synthesis [BOOK] (Pages: 199-236). WILEY-VCH GmbH, Weinheim, Germany. 2024. Print ISBN: 9783527352005, Online ISBN: 9783527841943, DOI:10.1002/9783527841943.

[2] 参编《有机化学. 第三版. 北京: 化学工业出版社, 2023.10