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成果及论文

(一)独立立组前代表性论文:

1、Zhang, Q.#; Wang, S.#, Li, W.; Yau, E.; Hui, H.; Singh, P.; Achuthan, V.; Karris, M. A. Y.; Engelman, A.; Rana, T. M.*.;Genome-wide CRISPR/Cas9 transcriptional activation screen identifies a histone acetyltransferase inhibitor complex as a regulator of HIV-1 integration;Nucleic Acids Research;2022;50(12): 6687–6701.

2、Wang, S.#Zhang, Q.#; Tiwari, S. K.#; Lichinchi, G.; Yau, E. H.; Hui, H.; Li, W.; Furnari, F.; Rana, T. M.*;Integrin αvβ5 internalizes Zika virus during neural stem cells infection and provides a promising target for antiviral therapy;Cell Reports2022;30,1–15.

3、Zhang, Q.#Kang, Y.; Wang, S.; Gonzalez, G. M.; Li, W.; Hui, H.; Wang, Y.; Rana, T. M*.;HIV reprograms host m6Am RNA methylome by viral Vpr protein-mediated degradation of PCIF1;Nature Communications2021;12(1):5543.

4、Wang, S.#; Zhang, Q.#; Hui, H.; Agrawal, K.; Karris, M. A. Y.; Rana, T. M.*;An atlas of immune cell exhaustion in HIV-infected individuals revealed by single-cell transcriptomics;

Emerging Microbes & Infections;2020; 9(1):2333-2347.

5、Zhang, Q.#; Chao, T. C.#; Patil, V. S.#; Qin, Y.; Tiwari, S. K.; Chiou, J.; Dobin, A.; Tsai, C. M.; Li, Z.; Dang, J.; Gupta, S.; Urdahl, K.; Nizet, V.; Gingeras, T. R.; Gaulton, K. J.; Rana, T. M.*.;The long noncoding RNA ROCKI regulates inflammatory gene expression;Embo Journal2019;38:e100041.

6、Chao, T. C.#; Zhang, Q.#; Li, Z.; Tiwari, S. K.; Qin, Y.; Yau, E.; Sanchez, A.; Singh, G.; Chang, K.; Kaul, M.; Karris, M. A. Y.; Rana, T. M.*.;The Long Noncoding RNA HEAL Regulates HIV-1 Replication through Epigenetic Regulation of the HIV-1 Promoter;mBio2019; 10(5). pii: e02016-19.

7、Zhang, Q.#;  Huang, C.Yang, Q.Gao, L. Liu, H. C. Tang, J.; Feng, W. H.*; MicroRNA-30c modulates type I IFN responses to facilitate porcine reproductive and respiratory syndrome virus infection by targeting JAK1. The Journal of Immunology2016196(5), 2272-2282.

8、Zhang, Q.#Tiwari, S. K.#; Wen, J. Wang, SWang, L.Li, W. Zhang, L.;  Rawling, S;  ChengY;  JokerstJ;   and Rana, T. M*.;Induction of neutralizing antibodies against SARS-CoV-2 variants by a multivalent mRNA-lipid nanoparticle vaccine encoding SARS-CoV-2/SARS-CoV Spike protein receptor-binding domains in mice. Plos one2024; 19 (4), e0300524.


(二)2022年独立立组后:

9、Wang, W. #; Sun, L.;  Huang, M.;  Quan, Y.;  Jiang, T,  Miao, Z.*;  Zhang, Q.* Regulatory circular RNAs in viral diseases: applications in diagnosis and therapy. RNA biology; 2023; 20 (1), 847-858.