44. Liu, B.; Dong, J.; Zhu, Q.; Zhang, J.; Huang, J.;Liu, S.; Zeng, X*.Copper-Catalyzed Perfluoroalkylation of propargyl gem-Dichlorides. Chem.Comm. 2024, 60, 12537 - 12540

This article is part of the themed collection: Chemical communications hot articles 2024

43.Liu, B.;^# Jiang, X.;^# Song, Y.;^# Liu, S.; Xiong, X.;* Zeng, X*. Copper-Catalyzed Cross Coupling Reaction of Alkyl Bromides with (DMPU)₂Zn(Rf)₂ Reagent: A Method for the Synthesis of Perfluoroalkylated Compounds. Adv. Synth. Catal. ASAP.

42. Jiang, X.; Gong, W.; Li, X.; Wang, S.; Gu, Z.; Yang, Y.; Zeng, X* Pd-Catalyzed Divergent Site-Selective Difluoromethylation and Difluoromethylcarbonylation of Aryl Sulfonium Salts. ACS Catal. 2024, 13557-13566.

Highlighted by 化学深耕堂 (https://mp.weixin.qq.com/s/BL-YUpeGQFMjFCVfPC-mmg)

Highlighted by WeeChem 微观化 (https://mp.weixin.qq.com/s/PcSi0IrqwanNJLLT53ycpQ)

Highlighted by 分子切块探索者（https://mp.weixin.qq.com/s/0Y_AMe_7mnSmWoaxcD0-NA）

Highlighted by Synfacts 2024 (https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0043-1775178)

41. J,Han*.; X,Lu.; L,Chen.; K,Gong.; B,Xu*.; X, Zeng*(Radio)Fluoro-iodination of Alkenes Enabled by a Hydrogen Bonding Donor Solvent.

Org.Lett.2024, 26, 3435-3440.

40. Xin,L*.; Yu,Yang.; Lie,Z.; X, Zeng*. Copper-Catalyzed Fluoroamide-Directed Remote C(sp3)-H Bond Functionalization Through Intramolecular Hydrogen Atom Transfer. Eur. J. Org.Chem.2024,27,  e2024000.  Invited review

  

39. Jiang, X.; Song, Y.; Peng, J.;^# Zhong, Z.;^# Chen, L.; X, Zeng*. Oxidant- and Base-Free, Copper-Catalyzed Difluoromethylation of Haloalkynes. Org.Lett. 2023,25, 8127–8132.

38.Du, Z.;^# Liu, S.;^# Li, Y.; Peng, J.; Sun, Y.; Song, Y.; Liu, Y.; X, Zeng*. Fluoroamide-Directed Regiodivergent C-Alkylation of Nitroalkanes. Org. Lett. 2023,25, 4632–4637.

 Featured in Org. Chem. Highlights.

37.Y. Liu, Z. Zhang, Z. Wei, Z. Zhong, S. Liu*, Y. Yang*, X. Zeng*. Catalyst-free Photochemical Reactions of Alkyl Dihydropyridines via Modulation of Chromophores and Light Wavelength. New J. Chem. 2023.47,7369-7374.

36. X, Zeng^#.; Wang, C^#.; Yan, W^#.; Rong, J^#.; Song, Y^#.; Xiao, Z.; Cai, A.; Liang, S. H*.; Liu, W*. Aryl Radical Enabled, Copper-Catalyzed Sonogashira-Type Cross-Coupling of Alkynes with Alkyl Iodides. ACS Catal. 2023, 2761-2770. 

35.S. Liu, Y. Zhang, K. Gong, X, Zeng*, F. Xie*, B. Xu*, J. Han*.Widely applicable (radio)dihalogenation of alkynes and alkenes using two different nucleophilic alkali metal halides. Org. Chem. Front. 2022.9,6826-6832.

34.Man, Y.; Liu, S.; Xu, B*.; X, Zeng*., N-Heterocyclic-Carbene-Catalyzed C–H Acylation via Radical Relay. Org. Lett. 2022,24,944-948.

Before NCU

33.  X, Zeng.+; Yan, W+.; Paeth, M.; Zacate, S. B.; Cai.A, Wang Y.; Yang, D.; Yang, K.; Liu, W*., “Copper-Catalyzed Deaminative Difluoromethylation”. ”Angew. Chem. Int. Ed. 2020,59,16398-16403. DOI: 10.1002/anie.202006048. (+ contributed equally)  Hot Paper.

32.  X, Zeng.; Liu,S.; Hao,Y.; Yi,Y.; Hammond, G. B*.; Xu, B*, “Widely Applicable Regio- and Stereoselective Synthesis of 1,2-Dihaloalkenes Using in situ Generated ICl, IBr, BrCl, I₂, and Br₂” DOI: org/10.1016/j.chempr.2020.03.011.  Chem, 2020,6, 1018-1031. 

31. X, Zeng.; Yan, W.; Paeth, M.; Zacate, S. B.; Hong, P.-H.; Wang, Y.; Yang, D.; Yang, K.; Yan, T.; Song, C.; Cao, Z*.; Cheng, M.-J.; Liu, W*., Copper-Catalyzed, Chloroamide-Directed Benzylic C−H Difluoromethylation. J. Am. Chem. Soc. 2019, 141, 19941-19949.

DOI:10.1021/jacs.9b11549. Highlights: Synfacts, GalChimia

30. X, Zeng.; Yan, W.; Zacate, S. B.; Chao, T.-H.; Sun, X.; Cao, Z*.; Bradford, K. G. E.; Paeth, M.; Tyndall, S. B.; Yang, K.; Kuo, T.-C.; Cheng, M.-J.; Liu, W*., "Copper Catalyzed    Decarboxylative Difluoromethylation". J. Am. Chem. Soc. 2019, 141, 11398-11403.

DOI: 10.1021/jacs.9b05363.Highlights: Synfacts, Synpacts

29. X, Zeng.; li,J.; Hammond, G. B*.; Xu, B*, “Nucleophilic (Radio)Fluoro-Click Reaction Enabled by Hydrogen Bonding Clusters” Angew. Chem. Int. Ed. 2018, 57, 2924-2928. DOI: org/10.1002/anie.201711341.

28. X, Zeng.; Liu, S.; Shi, Z.; Liu, G.; Xu, B*. “Synthesis of α-Fluoroketones by Insertion of HF into a Gold Carbene” Angew. Chem. Int. Ed. 2016, 55, 10032-10036. DOI: org/10.1002/anie.201603914.

27.  X, Zeng.; Liu, S.; Hammond, G. B*.; Xu, B*, “Hydrogen Bonding Assisted Brønsted Acid and Gold Catalysis: Access to both E- and Z-1, 2-Haloalkenes via Hydrochlorination of Haloalkynes” ACS Catal. 2018,8,904-909. 

26.  X, Zeng.; B.Chen.; Hammond, G. B*.; Xu, B*, “Homogeneous/Nanoparticle gold catalyzed Hydrothiocyanation of Haloalkynes” Org. Lett., 2019, 21, 2772-2776. 

25.  X, Zeng.; Lu, Z.; Liu, S.;  Hammond, G. B*.; Xu, B*, Metal-free, Regio-, and Stereo-Controlled Hydrochlorination and Hydrobromination of Ynones and Ynamides” J. Org. Chem. 2017, 83, 13179-13187.

 

24.  X, Zeng.; Liu, S.; Lu, Z.; Hammond, G. B*.; Xu, B*, “Gold-catalyzed Fluorination of Alkynyl Esters and Ketones: Efficient Access to Fluorinated 1,3-Dicarbonyl Compounds” Adv. Synth. Catal.,2017, 359,4062-4066. 

23.  X, Zeng.; Liu, S.; Hammond, G. B*.; Xu, B*, “Divergent Regio- and Stereoselective Gold-catalyzed Synthesis of α-Fluorosulfones and β-Fluorovinylsulfones from Alkynylsulfones” Chem. Eur. J. 2017, 23, 11977-11981. 

22.  X, Zeng.; Liu, S.; Z.Shi,; Xu, B*, “Hydrogen Bonding Cluster-Enabled Addition of Sulfonic Acids to Haloalkynes: Access to Both (E)- and (Z)-Alkenyl Sulfonates” Org. Lett. 2016, 18, 4770-4773. 

21.   X, Zeng.; Liu, S.; Xu, B*,“Stable Yet Reactive Cationic Gold Catalysts With Carbon Based Counterions” RSC Adv. 2016, 6, 77830-77833. 

20.  X, Zeng.; Smith, R.; Zhu, X*, “Synthesis of Thioglycoside Analogues of Maradolipid” J. Org. Chem. 2013, 78, 4165-4170.

19.      Liu, S.; Wang, L.; Ma, Z.; X, Zeng*.; Xu, B*., Pyridine hydrochloride-catalyzed thiolation of alkenes: divergent synthesis of allyl and vinyl sulfides. Organic Chemistry Frontiers 2020,7, 1690-1695.  

18.  S.Liu, ; X. Zeng*.; B. Xu*.“ Regio- and Stereoselective Halothiolation of Alkynes using Lithium Halides and N-thiosuccinimides” Org. Chem. Front. 2020, 7, 1690-1695. 

17.   S.Liu, ; X. Zeng*.; B. Xu*.“ Practical Fluorothiolation and Difluorothiolation of Alkenes using Pyridine-HF and N-thiosuccinimides” Org. Chem. Front. 2020,7,119-125.

16.   S.Liu.; Chen, B.; Yang, Y.; Yang, Y.; Chen, Q.; X. Zeng*.; B. Xu*, “Electrochemical oxidations of thioethers: Modulation of oxidation potential using a hydrogen bonding network”. Electrochem. Commun. 2019, 109, 106583. 

15.   L.Lin,; X. Zeng*.; B. Xu*.“Synthesis of Z‑Enamides through Heterogeneous Gold-Catalyzed Stereoselective Hydrogenation of Ynamides” J. Org. Chem. 2019, 83, 13179-13187. 

14.   B. Chen.; Y. Yang.; Y. Yang.; S. Liu.; Q. Chen.; X. Zeng*.; B. Xu*. “Effects of the Hydrogen Bonding Network on Electrophilic Activation and Electrode Passivation: Electrochemical Chlorination and Bromination of Aromatics”  ChemElectroChem., 2019, 6, 3726-3730. 

13.   S. Liu.; X. Zeng*.; B. Xu*.“Hydrogen bonding Assisted Regioselective sulfenylation and Trifluoromethylthiolation   of Electron-Rich (Het) arenes” Asian J. Org. Chem., 2019, 8, 1372-1375. 

12.   X. Xia.; B. Chen.; X. Zeng*.; B. Xu*. “Synthesis of α‐Trifluromethylthiolated and α‐Thiocyanated Ketones Using Umpoled Enolates” Adv. Synth. Catal.2018, 360, 4429-4437.

11.   X. Xia.; B. Chen.; X. Zeng*, B. Xu*. “Synthesis of α-Amino Ketones through Aminations of Umpoled Enolates” Org. Biomol. Chem. 2018,16,6918-6922.

10.    B. Chen.;  X. Xia.; X. Zeng*, B. Xu*. “Hydrogen Bonding Network Assisted Regio- and Stereo- Controlled Hydrohalogenation of Sulfonyl Alkynes” Tetrahedron Lett. 2018, 59,3950-3954. 

9. Cai, A., Yan, W., X, Zeng., Zacate, B. S., Chao, T-H., Krause, A. J., Cheng, M-J., Liu, W. "Copper-Catalyzed Carbo-Difluoromethylation of Alkenes via Radical Relay" Nat. Commun. 2021, 12, 3272

8. Lu, Z.; X, Zeng.; Hammond, G. B*.; Xu, B*. “Widely Applicable Hydrofluorination of Alkenes via Bifunctional Activation of Hydrogen Fluoride”J. Am. Chem. Soc. 2017, 139, 18202-18205. 

7.     Yang, Y.; Gao, X.; X, Zeng.; Han, J.; Xu, B., Hydrogen-Bond-Donor Solvents Enable Catalyst-Free (Radio)-Halogenation and Deuteration of Organoborons. Chem. Eur. J. 2021, 27 , 1297-1300.

6.  S. Liu.;  X. Zeng.;  G. B. Hammond*.;  B. Xu*, “Mild Base Promoted Nucleophilic Substitution of Unactivated sp³‐Carbon Electrophiles with Alkenylboronic Acids” Adv. Synth. Catal. 2018, 360, 3667-3671. 

5.  S. Liu.;  X. Zeng.;  B. Xu*, “Ligandless Copper‐Catalyzed Carboborylation of Heteroatom‐Substituted Alkynes” Adv. Synth. Catal. 2018, 360, 3249-3253. 

4. Liu, S., Meng, L., X, Zeng., Hammond, G.B. and Xu, B., Synthesis of Acrylonitriles via Mild Base Promoted Tandem Nucleophilic Substitution-Isomerization of α-Cyanohydrin Methanesulfonates. Chin. J. Chem.,2020 39,913-917

3.  Liu, S.; X, Zeng.; Xu, B*, “(E)-Alkene Synthesis via Nano-Copper/Homogeneous Palladium Co-Catalysis and Selectivity Amplification” Asian J. Org. Chem. 2017, 6, 507-511.

2.   Liu, S.; X, Zeng.; Xu, B*, “Cu^II-catalyzed Regioselective Borylation of Alkynes and Alkenes” Tetrahedron Lett. 2016, 57, 3706-3710.

1.    Smith, R.; X, Zeng.; Müller-Bunz, H.; Zhu, X*, “Synthesis of Glycosyl Disulfides Containing an α-Glycosidic Linkage” Tetrahedron Lett. 2013, 54, 5348-5350.