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成果及论文

2024

29. Yuanfeng Li#, Lei Hua#, Wei He#, Lei Chen, Yinzi Piao, Mengna Peng, Dongdong Li,* Linqi Shi, and Yong Liu*. Microenvironment-Adaptive Metallo-Polymeric Nanodecoys via Subcomponent Coordination for Bacterial Biofilm Eradication and Immunomodulation. Advanced Functional Materials. 2024, 2405487. https://doi.org/10.1002/adfm.202405487


28. Yumeng Wang#, Xinghong Zhao#, Xingjian Zhou#, Juqin Dai, Xiaowen Hu, Yinzi Piao, Guangyue Zu, Jian Xiao*, Keqing Shi*, Yong Liu*, Yuanfeng Li*, Linqi Shi.  A supramolecular hydrogel dressing with antibacterial, immunoregulation, and pro-regeneration ability for biofilm-associated wound healing. Journal of Controlled Release. 2024, 368, 740–755.

     https://doi.org/10.1016/j.jconrel.2024.03.024


27. Yinzi Piao#, Linzhu Su#, Xiaoli Hu#, Wei He, Xiaowen Hu, Calvin Andeve Omolo, Thirumala Govender*, Huaping*, Haodan Xue, Yicen Ge, Yong Liu*, Linqi Shi, Yuanfeng Li*. One-component lipidic bicontinuous nanospheres as a smart drug loading platform to eradicate candida biofilms in oral and vaginal infection. Nano Today. 2024, 54, 102123.https://doi.org/10.1016/j.nantod.2023.102123


26. Sidi Liu#, Yuanfeng Li#, Linqi Shi, Jian Liu, Yijin Ren, Jon D. Laman, Henny C. van der Mei*, Henk J. Busscher*. Maintaining sidedness and fluidity in cell membrane coatings supported on nano-particulate and planar surfaces. Bioactive Materials 2024, 32, 344.

 https://doi.org/10.1016/j.bioactmat.2023.10.010


25. Lei Chen#, Mengna Peng#, Huaping Li#, Jianan Zhou, Wei He, Rongdang Hu*, Fangfu Ye*, Yuanfeng Li*, Linqi Shi, and Yong Liu*. Metal-phenolic network with Pd nanoparticle nodes synergizes oxidase-like and photothermal properties to eradicate oral polymicrobial biofilm-associated infections. Advanced Materials. 202436, 2306376.

DOI:10.1002/adma.202306376. 



2023


24. Chaoyang Zhou*, Yong Liu*, Yuanfeng Li*, Linqi Shi. Recent advances and prospects in nanomaterials for bacterial sepsis management, Journal of Materials Chemistry B, 2023, 11, 10778.

  https://doi.org/10.1039/D3TB02220J


23. Yunhong Qian, Xiaoli Hu, Jinhui Wang, Yuanfeng Li*, Yong Liu*, Lingping Xie*. Polyzwitterionic micelles with antimicrobial conjugation for eradication of drug resistant bacterial biofilms. Colloids Surfaces B: Biointerfaces. 2023, 231, 113542.

113542. https://doi.org/10.1016/j.colsurfb.2023.113542.


22. Lei Chen#, Mengna Peng#, Jianan Zhou, Xiaowen Hu, Yinzi Piao, Huaping Li*, Rongdang Hu*, Yuanfeng Li*, Linqi Shi, Yong Liu* Supramolecular photothermal cascade nano-reactor enables photothermal effect, cascade reaction, and in situ hydrogelation for biofilm-associated tooth-extraction wound healing. Advanced Materials. 2023, 35, 2301664.

https://doi.org/10.1002/adma.202301664.


21. Xiaowen Hu#; Yuanfeng Li#; Yinzi Piao, Mahdi Karimi, Yang Wang*, Feng Wen, Huaqiong Li, Linqi Shi*, Yong Liu*. Two-tailed dynamic covalent amphiphile combats bacterial biofilms. Advanced Materials. 2023, 35, 2301623.

https://doi.org/10.1002/adma.202301623.


20. Yuxun Ding#, Xiaowen Hu#, Yinzi Piao, Rong Huang, Lingping Xie, Xiaojian Yan*, Hui Sun, Yuanfeng Li*; Linqi Shi, Yong Liu*. Lipid prodrug nanoassemblies via dynamic covalent boronates. ACS Nano. 2023, 17, 6601.

https://doi.org/10.1021/acsnano.2c12233.


19. Yuanfeng Li#, Hua Chen#, Keqing Shi, Juqin Dai, Siran Wang, Tieli Zhou*, Anh-Tuan Le, Yaran Wang, Fan Wu, Rujiang Ma*, Linqi Shi*, Yong Liu*. Dynamic covalent nano-networks comprising antibiotics and polyphenols orchestrate bacterial drug resistance reversal and inflammation alleviation. Bioactive Materials. 2023, 27, 288.

https://doi.org/https://doi.org/10.1016/j.bioactmat.2023.04.014.


18. Yizhou Zhan#, Xiaowen Hu#, Yuanfeng Li*, Yaran Wang, Hua Chen, Calvin Omolo, Thirumala Govender, Huaping Li*, Fan Huang*, Linqi Shi, Xiaoli Hu*, Yong Liu*. Antimicrobial hybrid amphiphile via dynamic covalent chemistry for eradication of staphylococcal biofilms. Advanced Functional Materials, 2023, 33, 2214299.

https://doi.org/10.1002/adfm.202214299.


17. Fan Wu#, Jinghang Ma#, Yang Wang,* Xiaojian Yan, Linqi Shi, Yuanfeng Li*, Yong Liu*. Single copper atom photocatalyst powers an integrated catalytic cascade for drug-resistant bacteria elimination. ACS Nano, 2023, 17, 2980.

https://doi.org/10.1021/acsnano.2c11550.


16. Yuanfeng Li, Junjie Chi, Pingwei Xu, Xing Dong, Anh Tuan Le, Keqing Shi*, Yong Liu*, Jian Xiao*. Supramolecular G-quadruplex hydrogels: bridging fabrication to biomedical application. Journal of Materials Science & Technology, 2023, 155, 238. https://doi.org/https://doi.org/10.1016/j.jmst.2023.01.034.


15. Cui, L.; Liu, S.; Wu, F.; Chen, H.; Li, Y.; Shi, L.; Liu, Y.; Ma, R. Protein@PP-Zn Nanocomplex Assembled by Coordination of Zinc Ions Used for Intracellular Protein Delivery. Sci. China Chem. 202366 (8), 2354–2362. https://doi.org/10.1007/s11426-023-1634-5.


2022


14. Linyan Nie, Yuanfeng Li, Yong Liu, Linqi Shi*, Huiyun Chen*. Recent applications of contact lenses for bacterial corneal keratitis therapeutic: A review. Pharmaceutics 2022 https://www.mdpi.com/1999-4923/14/12/2635


13. Yaran Wang#, Jianan Zhou#, Lu Yuan#, Fan Wu, Lingping Xie, Xiaojian Yan, Huaping Li*, Yuanfeng Li*, Linqi Shi, Rongdang Hu*, Yong Liu*. Neighboring Carboxylic Acid Boosts Peroxidase-Like Property of Metal-Phenolic Nano-Networks in Eradicating Streptococcus mutans Biofilms. Small2022. 2206657. https://doi.org/10.1002/smll.202206657


12. Yin-Zi Piao#,Yu Qi#, Xiao-Wen Hu, Yaran Wang, Yuanfeng Li,* Tieli Zhou, Linqi Shi,* Yong Liu,* and Chaoyang Zhou*. GOx-encapsulated iron-phenolic networks power catalytic cascade to eradicate bacterial biofilms. Journal of Controlled Release2022, 352, 1-14.  https://doi.org/10.1016/j.jconrel.2022.10.013


11. Yuanfeng Li, Linzhu Su, Yongxin Zhang, Yong Liu*, Fan Huang*, Yijin Ren, Yingli An, Linqi Shi*, Henny C. van der Mei*, Henk J. Busscher. A G-quadruplex Hydrogel as Cascade Reaction Container Consuming Endogenous Glucose for Infected Wound Treatment–a Study in Diabetic Mice, Advanced Science 2022, 2103485. https://doi.org/10.1002/advs.202103485


10. Linzhu Su, Yong Liu*, Yuanfeng Li, Yingli An, Linqi Shi.*  Polymer-based materials for biofilm-infection control, Chinese Journal of Polymer Science, Accepted. http://www.cjps.org/article/doi/10.1007/s10118-021-2610-3


9. Yong Liu#, Yuanfeng Li#, Linqi Shi*. Controlled drug delivery systems in eradicating bacterial biofilm-associated infections. Journal of Controlled Release, 2021, 329, 1102-1116. https://doi.org/10.1016/j.jconrel.2020.10.038


 2020


8. Yuanfeng Li#Yong Liu#, Yijin Ren, Linzhu Su, Ang Li, Yingli An, Vincent Rotello, Zhanzhan Zhang, Yin Wang, Yang Liu, Sidi Liu, Jian Liu, Jon D Laman, Linqi Shi*, Henny C van der Mei*, Henk J Busscher. Coating of a Novel Antimicrobial Nanoparticle with a Macrophage Membrane for the Selective Entry into Infected Macrophages and Killing of Intracellular Staphylococci. Advanced Functional Materials 2020, 30, 2004942. https://doi.org/10.1002/adfm.202004942


7. Linzhu Su, Yuanfeng LiYong Liu*, Rujiang Ma, Yang Liu, Fan Huang*, Yingli An, Yijin Ren, Henny C van der Mei, Henk J Busscher*, Linqi Shi*. Antifungal‐Inbuilt Metal–Organic‐Frameworks Eradicate Candida albicans Biofilms. Advanced Functional Materials 2020, 30, 2000537. https://doi.org/10.1002/adfm.202000537


2019


6. Hejin Shi#Yong Liu#, Rui Qu, Yuanfeng Li, Rujiang Ma*, Yingli An, Linqi Shi*. A facile one-pot method to prepare peroxidase-like nanogel artificial enzymes for highly efficient and controllable catalysis. Colloids and Surfaces B: Biointerfaces, 2019, 174, 352-359. https://doi.org/10.1016/j.colsurfb.2018.11.021.


5. Yong Liu, Yuanfeng Li, Damla Keskin, Linqi Shi*. Poly (β‐Amino Esters): Synthesis, Formulations, and Their Biomedical Applications. Advanced healthcare materials, 2019, 8(2), 1801359. https://doi.org/10.1002/adhm.201801359


2018


4. Yong Liu, Yijin Ren, Yuanfeng Li, Linzhu Su, Yumin Zhang, Fan Huang, Jinjian Liu, Jianfeng Liu, Theo G van Kooten, Yingli An, Linqi Shi*, Henny C van der Mei*, Henk J Busscher. Nanocarriers with conjugated antimicrobials to eradicate pathogenic biofilms evaluated in murine in vivo and human ex vivo infection models. Acta biomaterialia, 2018, 79, 331-343. https://doi.org/10.1016/j.actbio.2018.08.038.


2017

3. Yong Liu, Henny C van der Mei*, Bingran Zhao, Yan Zhai, Tangjian Cheng, Yuanfeng Li, Zhenkun Zhang, Henk J Busscher, Yijin Ren, Linqi Shi*. Eradication of Multidrug‐Resistant Staphylococcal Infections by Light‐Activatable Micellar Nanocarriers in a Murine Model. Advanced Functional Materials, 2017, 27(44), 1701974. https://doi.org/10.1002/adfm.201701974.


2. Yuanfeng Li#Yong Liu#, Rujiang Ma, Yanling Xu, Yunliang Zhang, Baoxin Li, Yingli An, Linqi Shi. A G-quadruplex hydrogel via multicomponent self-assembly: formation and zero-order controlled release. ACS applied materials & interfaces, 2017, 9(15), 13056-13067. https://doi.org/10.1021/acsami.7b00957.


2016

1. Yong Liu, Henk J Busscher, Bingran Zhao, Yuanfeng Li, Zhenkun Zhang, Henny C van der Mei*, Yijin Ren, Linqi Shi*. Surface-adaptive, antimicrobially loaded, micellar nanocarriers with enhanced penetration and killing efficiency in staphylococcal biofilms. ACS Nano, 2016, 10(4), 4779-4789. https://doi.org/10.1021/acsnano.6b01370