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​陈归 2021年博士生     进组时间: 2018


基本情况:陈归,2021级博士研究生, 2018年推免至南方医科大学攻读药剂学博士(2021年硕博连读);本科毕业第一作者或者共同一作发表SCI两篇,以及多篇研究性学术成果。

科研成果:以一作或共同一作在TOP期刊 ACS Nano, Nano Letters, Journal of Controlled Release等国际国内学术刊物上发表10余篇文章(IF>10);参与专利一项。另外在投文章两篇,有三个相关性课题在研究。

发表论文:

1. Chen G#, Xu Q#, Feng ZZ, Xu QQ, Zhang XH, Yang YY, Zhang YX, Liang XJ*, Yu ZQ*, Yu M*. Glutamine antagonist synergizes with electrodynamic therapy to induce tumor regression and systemic antitumor immunity. ACS Nano, 2022, 16(1): 951-962. (SCI一区,TOP期刊,IF=18.027)

2. Chen G#, Yang Y#, Xu Q, Ling M, Lin H, Ma W, Sun R, Xu Y, Liu X, Li N, Yu Z*, Yu M*. Self-amplification of tumor oxidative stress with degradable metallic complexes for synergistic cascade tumor therapy. Nano Letters. 2020, 20(11):8141-8150. (SCI一区,TOP期刊,IF=12.262)

3. Xu Q#, Chen G#, Chen GM, Wu HL, Yang YY, Mai ZY, Sun R, Luan P, Guo CW, Yu M*, Peng ZW*, Yu ZQ*. NO-dependent vasodilation and deep tumor penetration for cascade amplified antitumor performance. Journal of Controlled Release, 2022, 347: 389-399. (SCI一区,TOP期刊,IF=11.467)

4. Qiao G#, Chen G#, Wen Q, Liu W, Gao J, Yu Z*, Wang Q*. Rapid conversion from common precursors to carbon dots in large scale: spectral controls, optical sensing, cellular imaging and LEDs application. Journal of Colloid and Interface Science, 2020, 580:88-98. (SCI二区,TOP期刊,IF=9.871)

5. Chen G#, Shen Y#, Li X, Jiang Q, Cheng S, Gu Y, Liu L, Cao Y. The endoplasmic reticulum stress inducer thapsigargin enhances the toxicity of ZnO nanoparticles to macrophages and macrophage-endothelial co-culture. Environmental Toxicology and Pharmacology. 2017, 50:103-110. (SCI三区,IF=5.785)

6. Shen Y#, Chen G#, Xiao A, Xie Y, Liu L, Cao Y. In vitro effect of flaxseed oil and α-linolenic acid against the toxicity of lipopolysaccharide (LPS) to human umbilical vein endothelial cells. Inflammopharmacology. 2018, 26(2):645-654. (SCI三区,IF=5.0925)

7. Gu Y#, Cheng S#, Chen G, Shen Y, Li X, Jiang Q, Li J, Cao Y. The effects of endoplasmic reticulum stress inducer thapsigargin on the toxicity of ZnO or TiO2 nanoparticles to human endothelial cells. Toxicology Mechanisms and Methods. 2017, 27(3):191-200. (SCI四区,IF=4.0189)

在投文章:

Xuzi Cai#, Xiaoxia Xu#, Gui Chen#, Rongqiu Qin, Yuanyuan Yang, Ziyi Mai, Yang Tian, Jinxiu Tan, Lijuan He, Yuanling Xiao, Zhiqiang Yu*, Xuefeng Wang*, Glutamine Starvation for Cisplatin Sensitization in Ovarian Cancer Treatment. Acta Biomaterialia. (under review, SCI一区,TOP期刊,IF=10.633) 

参与“大创”项目:

1. 铁掺杂光热载体在转移性乳腺癌治疗上的应用及免疫学机制研究

2. 温敏型脂质体递药系统构建以及抗癌机制研究 

获奖情况:

2018年推免生奖学金、2020年“时代”奖学金、2021-2022年博士新生奖学金、2021-2022年优秀研究生、2022年国家研究生奖学金。

研究方向:

1. Pt基金属复合物促进化学动力学治疗联合免疫药物激活全身性免疫抗肿瘤

2. 一种新型电气治疗诱发ICD效应来增强肿瘤免疫治疗及其机制研究

爱好:跳舞、唱歌

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