ORCID: 0000-0003-1360-8931

2024

53. Jie Wang^†, Yee Lin Phang^†, You-Jie Yu, Nan-Nan Liu, Qiang Xie, Feng-Lian Zhang, Ji-Kang Jin*, Yi-Feng Wang*

Boryl Radical as a Catalyst in Enabling Intra- and Intermolecular Cascade Radical Cyclization Reactions: Construction of Polycyclic Molecules

Angew. Chem. Int. Ed. 2024, 63, e202405863.

52. Yee Lin Phang, Ji-Kang Jin, Feng-Lian Zhang*, Yi-Feng Wang*

Radical hydroboration for the synthesis of organoboron compounds

Chem. Commun. 2024, 60, 4275-4289.

51. Ming-Cheng Bo, Yee Lin Phang, Qiang Zhao, Feng-Lian Zhang*, Yi-Feng Wang*

Lewis Base-Boryl Radicals Promoted Selective Mono- and Di- Hydrodechlorination of Trichloroacetamides and Acetates

Eur. J. Org. Chem. 2024, 27, e202301189.

50. Yee Lin Phang, Feng-Lian Zhang*, Yi-Feng Wang*

Recent applications of heteroatom-centered radicals as catalysts in organic synthesis

ARKIVOC 2024, 202312052. (Dedicated to Professor Samir Z. Zard for his contribution to radical chemistry)

2023

49. Chang-Ling Wang^†, Jie Wang^†, Ji-Kang Jin^†, Bin Li, Yee Lin Phang, Feng-Lian Zhang*, Tian Ye, Hui-Min Xia, Li-Wen Hui, Ji-Hu Su, Yao Fu*, Yi-Feng Wang*

Boryl radical catalysis enables asymmetric radical cycloisomerization reactions

Science 2023, 382, 1056-1065.

48. Tian-Yu Peng,^† Feng-Lian Zhang,^† Yi-Feng Wang*

Lewis Base-Boryl Radicals Enabled Borylation Reactions and Selective Activation of Carbon-Heteroatom Bonds

Acc. Chem. Res. 2023, 56, 169-186.

47. Nan-Nan Liu, Xuan-Chen Wan, Li-Wen Hui, Feng-Lian Zhang*, Yi-Feng Wang*

Boryl Radical-Promoted Deoxygenative Alkylation of Benzyl Acetates

Synthesis 2023, DOI: 10.1055/s-0042-1751463. (Special Issue New Trends in Organic Synthesis from Chinese Chemists)

46. Qiu-Yu Gu, Tian-Yu Peng, Ming-Cheng Bo, Yi-Feng Wang*

Boryl Radicals-enabled Selective Mono- and Di-deuterodefluorination of Trifluoroacetamides

Chin. J. Org. Chem. 2023, 43, 1832-1842.

2022

45. Qiang Zhao,^† Bin Li,^† Xi Zhou, Zhao Wang, Feng-Lian Zhang,* Yuanming Li, Xiaoguo Zhou, Yao Fu,* and Yi-Feng Wang* 

Boryl Radicals Enabled a Three-Step Sequence to Assemble All-Carbon Quaternary Centers from Activated Trichloromethyl Groups

J. Am. Chem. Soc. 2022, 144, 15275-15285.

44. Tian-Yu Peng,^† Zhe-Yuan Xu,^† Feng-Lian Zhang*, Bin Li, Wen-Ping Xu, Yao Fu*, Yi-Feng Wang* 

Dehydroxylative Alkylation of α-Hydroxy Carboxylic Acids Derivatives via Spin-center Shift

Angew. Chem. Int. Ed. 2022, e202201329.

43. Feng-Lian Zhang, Bin Li, K. N. Houk*, Yi-Feng Wang* 

Application of the Spin-Center Shift in Organic Synthesis

JACS Au, 2022, 2, 1032-1042.

42.  Tian Ye,^† Feng-Lian Zhang,^† Hui-Min Xia, Xi Zhou, Zhi-Xiang Yu*, Yi-Feng Wang* 

Stereoselective Hydrogen Atom Transfer to Acyclic Radicals: a Switch Enabling Diastereodivergent Borylative Radical Cascades

Nat. Commun. 2022, 13, 426.

41.  Tesfaye Tebeka Simur,† Fentahun Wondu Dagnaw,† You-Jie Yu, Feng-Lian Zhang*, and Yi-Feng Wang* 

4-Dimethylaminopyridine-Boryl Radical Promoted Monodefluorinative Alkylation of 3,3-Difluorooxindoles

Chin. J. Chem. 2022, 40, 577-581.

2021

40.  You-Jie Yu,^† Feng-Lian Zhang,^† Tian-Yu Peng, Chang-Ling Wang, Jie Cheng, Chen, Chen, Kendall N. Houk*, Yi-Feng Wang*

Sequential C-F bond functionalizations of trifluoroacetamides and acetates via spin-center shifts

Science 2021, 371, 1232-1240.

39. Tesfaye Tebeka Simur,^† Tian Ye,^†  You-Jie Yu, Feng-Lian Zhang*, Yi-Feng Wang* 

C–F Bond Functionalizations of Trifluoromethyl Groups via Radical Intermediates

Chin. Chem. Lett. 2021, 33, 1193-1198.

38. Yun-Shuai Huang, Xiao-Hui Jin, Feng-Lian Zhang*, Yi-Feng Wang*

4-Dimethylaminopyridine-Boryl Radical Promoted Regioselective Radical Hydroboration of Electron-Deficient Alkenes

Chin. J. Org. Chem. 2021, 41, 1957-1967.

2020

37.  Ji-Kang Jin, Hui-Min Xia, Feng-Lian Zhang, Yi-Feng Wang*

Lewis-base Boryl Radicals Enabled Borylation, Radical Catalysis, and Reduction Reactions

Chin. J. Org. Chem. 2020, 40, 2185-2194.

(Account in Chinese)

36.  Bi-Yang Zhuang, Ji-Kang Jin, Feng-Lian Zhang*, Yi-Feng Wang*

Radical Hydroboration-Involved One-Pot Synthesis of Boron-Handled Glycol Derivatives

Synlett 2021, 32, 383-386.(Cluster on ‘Radicals – by Young Chinese Organic Chemists’)

35.  Jing Qi, Feng-Lian Zhang, Ji-Kang Jin, Qiang Zhao, Bin Li, Lin-Xuan Liu, Yi-Feng Wang*

New Radical Borylation Pathways for Organoboron Synthesis Enabled by Photoredox Catalysis

Angew. Chem. Int. Ed. 2020, 59, 12876-12884.

34. Qiang Zhao, Ji-Kang Jin, Jie Wang, Feng-Lian Zhang*, Yi-Feng Wang*

Radical α-Addition Involved Electrooxidative [3+2] Annulation of Phenols and Electron-Deficient Alkenes

Chem. Sci. 2020, 11, 3909-3913.

2019

33. Ji-Kang Jin, Wan-Xin Zheng, Hui-Min Xia, Feng-Lian Zhang*, Yi-Feng Wang*

Regioselective Radical Hydroboration of gem-Difluoroalkenes: Synthesis of α-Borylated Organofluorines

Org. Lett. 2019, 21, 8414-8418.

32. Yun-Shuai Huang, Jie Wang, Wan-Xin Zheng, Feng-Lian Zhang, You-Jie Yu, Min Zheng, Xiaoguo Zhou*, Yi-Feng Wang*

Regioselective radical hydroboration of electron-deficient alkenes: synthesis of α-boryl functionalized molecules

Chem. Commun. 2019, 55, 11904-11907.

31. Ai-Qing Xu,^† Feng-Lian Zhang,^† Tian Ye, Zhi-Xiang Yu,* Yi-Feng Wang*

NHC-Boryl Radical Catalysis for Cycloisomerization with C-C Triple Bond Reorganization

CCS Chem. 2019, 1, 504-512. 

30. Ji-Kang Jin, Feng-Lian Zhang,* Yi-Feng Wang*

Lewis Base-Boryl Radical Enabled Giese Reaction and Barton Decarboxylation of NHPI Esters

Acta Chim. Sinica 2019, 77, 889-894.

29. Shi-Chao Ren,^† Feng-Lian Zhang,^† Ai-Qing Xu, Yinuo Yang, Min Zheng, Xiaoguo Zhou*, Yao Fu*, Yi-Feng Wang*

Regioselective radical α-borylation of α,β-unsaturated carbonyl compounds for direct synthesis of α-borylcarbonyl molecules

Nat. Commun. 2019, 10, 1934.

2018

28. Ji-Kang Jin, Feng-Lian Zhang, Qiang Zhao, Jun-An Lu, Yi-Feng Wang*

Synthesis of Diverse Boron-Handled N-Heterocycles via Radical Borylative Cyclization of N-Allylcyanamides

Org. Lett. 2018, 20, 7558-7562.

27. Hui-Min Xia,^† Feng-Lian Zhang,^† Tian Ye, Yi-Feng Wang*

Selective α-Monomethylation by an Amine-Borane/N,N-Dimethylformamide System as the Methyl Source

Angew. Chem. Int. Ed. 2018, 57, 11770-11775.

26. Jing Qi, Feng-Lian Zhang, Yun-Shuai Huang, Ai-Qing Xu, Shi-Chao Ren, Zhen-Yu Yi, Yi-Feng Wang*

Radical Borylative Cyclization of 1,6-Dienes: Synthesis of Boron-Substituted Six-Membered Heterocycles and Carbocycles

Org. Lett. 2018, 20, 2360-2364.

25. You-Jie Yu, Feng-Lian Zhang, Jie Cheng, Jing-Hao Hei, Wei-Ting Deng, Yi-Feng Wang*

Lewis Base–Boryl Radicals Enabled the Desulfurizative Reduction and Annulation of Thioamides

Org. Lett. 2018, 20, 24-27.

2017

24. Shi-Chao Ren, Feng-Lian Zhang, Jing Qi, Yun-Shuai Huang, Ai-Qing Xu, Hong-Yi Yan, Yi-Feng Wang*

Radical Borylation/Cyclization Cascade of 1,6-Enynes for the Synthesis of Boron-Handled Hetero- and Carbocycles

J. Am. Chem. Soc. 2017, 139, 6050-6053.

Postdoc and PhD work

23. Yi-Feng Wang, Ming Hu, Hirohito Hayashi, Bengang Xing,* and Shunsuke Chiba*

      Linking of Alcohols with Vinyl Azides

      Org. Lett. 2016, 18, 992-995.

22.  Yi-Feng Wang, Geoffroy Hervé Lonca, Le Runigo Maiwenn, and Shunsuke Chiba*

      Synthesis of Polyfluoroalkyl Aza-Polycyclic Aromatic Hydrocarbons Enabled by Addition of Perfluoroalkyl Radicals onto Vinyl Azides

      Org. Lett. 2014, 16, 4272–4275.

21.  Yi-Feng Wang, Geoffroy Hervé Lonca, and Shunsuke Chiba*

PhI(OAc)2-Mediated Radical Trifluoromethylation of Vinyl Azides with Me3SiCF3

Angew. Chem. Int. Ed. 2014, 53, 1067–1071.

20.  Feng-Lian Zhang, Yi-Feng Wang, Geoffroy Hervé Lonca, Xu, Zhu, Shunsuke Chiba*

Amide Synthesis by Nucleophilic Attack of Vinyl Azides

Angew. Chem. Int. Ed. 2014, 4390–4394. 

19.    Xu Zhu, Yi-Feng Wang, Feng-Lian Zhang, and Shunsuke Chiba*

Formal [4+2]-annulation of vinyl azides with N-unsaturated aldimines

Chem. Asian J. 2014, 9, 2458-2462.

18.    Kah Kah Toh, Anup Biswas, Yi-Feng Wang, Yun Yun Tan, and Shunsuke Chiba*

Copper-mediated oxidative transformation of N‑allyl enamine carboxylates toward synthesis of azaheterocycles

J. Am. Chem. Soc. 2014, 136, 6011−6020.   

17.   Xu Zhu, Yi-Feng Wang, Wei Ren, Feng-Lian Zhang, and Shunsuke Chiba*

TEMPO-Mediated Aliphatic C-H Oxidation with Oximes and Hydrazones

Org. Lett. 2013, 15, 3214−3217.

16.  Yi-Feng Wang,† Feng-Lian Zhang,† and Shunsuke Chiba*

Oxidative Radical Skeletal Rearrangement Induced by Molecular Oxygen: Synthesis of Quinazolinones

Org. Lett. 2013, 15, 2842−2845.

15.     Feng-Lian Zhang, Yi-Feng Wang, and Shunsuke Chiba*

Orthogonal aerobic conversion of N-benzyl amidoximes to 1,2,4-oxadiazoles or quinazolinones

Org. Biomol. Chem. 2013, 11, 6003−6007.

14.   Hui Chen, Stephen Sanjaya, Yi-Feng Wang, and Shunsuke Chiba*

Copper-Catalyzed Aliphatic C-H Amination with an Amidine Moiety

Org. Lett. 2013, 15, 212−215.

13.   Yi-Feng Wang,† Hui Chen,† Xu Zhu, and Shunsuke Chiba*

Copper-Catalyzed Aerobic Aliphatic C–H Oxygenation Directed by an Amidine Moiety

J. Am. Chem. Soc. 2012, 134, 11980−11983.

12.    Yi-Feng Wang,† Xu Zhu,† and Shunsuke Chiba*

Copper-Catalyzed Aerobic [3+2]-Annulation of N-Alkenyl Amidines

J. Am. Chem. Soc. 2012, 134, 3679−3682.

11.    Yi-Feng Wang, Feng-Lian Zhang, and Shunsuke Chiba*

Copper-Catalyzed Aerobic Methyl/Methylene Oxygenation and C-H Formylation under DABCO–DMSO System for Synthesis of Carbonyl Indoles and Pyrroles

Synthesis 2012, 44, 1526−1534. (Special Issue on Copper in Organic Synthesis)

10.   Kah Kah Toh,† Yi-Feng Wang,† Eileen Pei Jian Ng, and Shunsuke Chiba*

Copper-Mediated Aerobic Synthesis of 3-Azabicyclo[3.1.0]hex-2-enes and 4-Carbonylpyrroles from N-Allyl/Propargyl Enamine Carboxylates

J. Am. Chem. Soc. 2011, 133, 13942−13945.

9.   Yi-Feng Wang, Kah Kah Toh, Jian-Yuan Lee, and Shunsuke Chiba*

Synthesis of Isoquinolines from α-Aryl Vinyl Azides and Internal Alkynes by Rh-Cu Bimetallic Cooperation

Angew. Chem. Int. Ed. 2011, 50, 5927−5931.   

8.     Yi-Feng Wang, Kah Kah Toh, Eileen Pei Jian Ng, and Shunsuke Chiba*

Mn(III)-Mediated Formal [3+3]-Annulation of Vinyl Azides and Cyclopropanols: A Divergent Synthesis of Azaheterocycles

J. Am. Chem. Soc. 2011, 133, 6411−6421.

7.     Eileen Pei Jian Ng, Yi-Feng Wang, Benjamin Wei-Qiang Hui, Guillaume Lapointe, and Shunsuke Chiba*

Orthogonal synthesis of pyrroles and 1,2,3-triazoles from vinyl azides and 1,3-dicarbonyl compounds

Tetrahedron 2011, 67, 7728−7737.

6.     Eileen Pei Jian Ng, Yi-Feng Wang, and Shunsuke Chiba*

Manganese(III)-Catalyzed Formal [3+2] Annulation of Vinyl Azides and β-Keto Acids for Synthesis of Pyrroles

Synlett 2011, 783−786.

5.     Pei Chui Too, Yi-Feng Wang, and Shunsuke Chiba*

Rhodium(III)-Catalyzed Synthesis of Isoquinolines from Aryl Ketone O-Acyloxime Derivatives and Internal Alkynes

Org. Lett. 2010, 12, 5688−5691.

4.     Yi-Feng Wang and Shunsuke Chiba*

Mn(III)-Mediated Reactions of Cyclopropanols with Vinyl Azides: Synthesis of Pyridine and 2–Azabicyclo [3.3.1]non -2-en-1-ol Derivatives

J. Am. Chem. Soc. 2009, 131, 12570−12572.

3.     Shunsuke Chiba,* Yan-Jun Xu, and Yi-Feng Wang

A Pd(II)-Catalyzed Ring-Expansion Reaction of Cyclic 2-Azidoalcohol Derivatives: Synthesis of Azaheterocycles

J. Am. Chem. Soc. 2009, 131, 12886−12887.

2.      Yi-Feng Wang, Kah Kah Toh, Shunsuke Chiba,* and Koichi Narasaka*

Mn(III)-Catalyzed Synthesis of Pyrroles from Vinyl Azides and 1,3-Dicarbonyl Compounds

Org. Lett. 2008, 10, 5019−5022.

1.     Shunsuke Chiba,* Yi-Feng Wang, Guillaume Lapointe, and Koichi Narasaka*

Synthesis of Polysubstituted N-H Pyrroles from Vinyl Azides and 1,3-Dicarbonyl Compounds

Org. Lett. 2008, 10, 313−319.