近五年代表性论著：

1.    Zhong, Y.; Liu, H.; Chen, F.; He, Q.; Zhang, X.; Lan, L.; Yang, C., Design, synthesis and biological evaluation of thiazolyl-halogenated pyrroles or pyrazoles as novel antibacterial and antibiofilm agents. Eur J Med Chem 2024, 268, 116221.

2.    Zhuang, Z.; Sun, Y.; Zhong, Y.; He, Q.; Zhang, X.; Yang, C., Visible-Light-Induced Decarboxylative Aminosulfonylation of (Hetero)aryl Carboxylic Oxime Esters. Org. Lett. 2024, 26 (3), 713-718.

3.    Cheng, Y. J.; Zhuang, Z.; Miao, Y. L.; Song, S. S.; Bao, X. B.; Yang, C. H.; He, J. X., Identification of YCH2823 as a novel USP7 inhibitor for cancer therapy. Biochem. Pharmacol. 2024, 222, 116071.

4.    Tan, J.; He, Y.; Lin, Y.; Zhong, Y.; He, S.; Zuo, J.; Yang, C., Synthesis of 2-amino-9H-chromeno[2,3-d]thiazol-9-ones with anti-inflammatory activity via cascade reactions of 2-amino-3 iodochromones with amines and carbon disulfide. RSC Advances 2024, 14 (5), 3158-3162.

5.    Sun, Y.; Yang, H.; Yuan, J.; Wang, L.; Song, S.; Chen, R.; Bao, X.; Jia, L.; Yang, T.; Zhang, X.; He, Q.; Gan, Y.; Miao, Z.; He, J.; Yang, C., YCH1899, a Highly Effective Phthalazin-1(2H)-one Derivative That Overcomes Resistance to Prior PARP Inhibitors. J Med Chem 2023, 66 (17), 12284-12303.

6.    Yang, K.; Li, S.; Wang, T.; Yan, X.; He, Q.; Ning, R.; Xu, X.; Yao, W.; Zhang, X.; Yang, C.; Jiang, M.; Deng, L., Development of an Orally Active Small-Molecule Inhibitor of Receptor Activator of Nuclear Factor-kappaB Ligand. J Med Chem 2022, 65 (16), 10992-11009.

7.    Huan, X.; Wang, Y.; Peng, X.; Xie, S.; He, Q.; Zhang, X.; Lan, L.; Yang, C., Design, synthesis, and biological evaluations of substituted pyrazoles as pyrrolomycin analogues against staphylococcal biofilm. Eur J Med Chem 2022, 236, 114309.

8.    Liu, F.; Zhuang, Z.; Qian, Q.; Zhang, X.; Yang, C., Ru-Catalyzed Defluorinative Alkylation or Catalyst-Free Hydroalkylation of gem-Difluoroalkenes Enabled by Visible Light. J. Org. Chem. 2022, 87 (5), 2730-2739.

9.    Zhang, Z.; He, Q.; Zhang, X.; Yang, C., Photoredox-catalysed regioselective synthesis of C-4-alkylated pyridines with N-(acyloxy)phthalimides. Org Biomol Chem 2022, 20 (9), 1969-1973.

10.   Wang, J.; Wei, W.; Zhang, X.; Cao, S.; Hu, B.; Ye, Y.; Jiang, M.; Wang, T.; Zuo, J.; He, S.; Yang, C., Synthesis and Biological Evaluation of C-17-Amino-Substituted Pyrazole-Fused Betulinic Acid Derivatives as Novel Agents for Osteoarthritis Treatment. J Med Chem 2021, 64 (18), 13676-13692.

11.   Xiang, H. Y.; Wang, X.; Chen, Y. H.; Zhang, X.; Tan, C.; Wang, Y.; Su, Y.; Gao, Z. W.; Chen, X. Y.; Xiong, B.; Gao, Z. B.; Chen, Y.; Ding, J.; Meng, L. H.; Yang, C. H., Identification of methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) as an orally bioavailable, highly potent, PI3K alpha inhibitor for the treatment of advanced solid tumors. Eur J Med Chem 2021, 209, 112913.

12.   Li, S.; Zhang, L.; He, Q.; Zhang, X.; Yang, C., Synthesis of 2-alkyl-chroman-4-ones via cascade alkylation-dechlorination of 3-chlorochromones. Org Biomol Chem 2021, 19 (24), 5348-5352.

13.   Yuan, J.; Zhang, X.; Yang, C., Regioselective Pd-catalyzed alpha-alkylation of furans using alkyl iodides. RSC Adv 2021, 11 (23), 13832-13838.

14.   Dai, T.; Cui, C.; Qi, X.; Cheng, Y.; He, Q.; Zhang, X.; Luo, X.; Yang, C., Regioselective synthesis of substituted thiazoles via cascade reactions from 3-chlorochromones and thioamides. Org Biomol Chem 2020, 18 (31), 6162-6170.

15.   Jiang, M.; Peng, L.; Yang, K.; Wang, T.; Yan, X.; Jiang, T.; Xu, J.; Qi, J.; Zhou, H.; Qian, N.; Zhou, Q.; Chen, B.; Xu, X.; Deng, L.; Yang, C., Development of Small-Molecules Targeting Receptor Activator of Nuclear Factor-κB Ligand (RANKL)—Receptor Activator of Nuclear Factor-κB (RANK) Protein–Protein Interaction by Structure-Based Virtual Screening and Hit Optimization. J. Med. Chem. 2019, 62 (11), 5370-5381.

16.   Dai, T.; Li, Q.; Zhang, X.; Yang, C., Substituent-Oriented Synthesis of Substituted Pyrazoles/Chromeno[3,2-c]pyrazoles via Sequential Reactions of Chromones/3-Chlorochromones and Tosylhydrazones. J. Org. Chem. 2019, 84 (9), 5913-5921.

17.   Peng, X.; Zhang, X.; Li, S.; Lu, Y.; Lan, L.; Yang, C., Silver-mediated synthesis of novel 3-CF3/CN/phosphonate-substituted pyrazoles as pyrrolomycin analogues from 3-formylchromones and diazo compounds. Org. Chem. Front. 2019, 6 (11), 1775-1779.

18.   Peng, Y.; He, Q.; Zhang, X.; Yang, C., Pd-Catalyzed intramolecular C–H activation and C–S formation to synthesize pyrazolo[5,1-b]benzothiazoles without an additional oxidant. Org. Chem. Front. 2019, 6 (18), 3234-3237.