成果及论文 - 南开大学杨志谋课题组

2023年
A Cascade-Targeted Enzyme-Instructed Peptide Self-Assembly Strategy for Cancer Immunotherapy through Boosting Immunogenic Cell Death, Limin Xie, Yinghao Ding, Xiangyang Zhang, Zhenghao Zhang, Sheng Zeng, Ling Wang*, Zhimou Yang, Qian Liu*, Zhi-Wen Hu*, Small Methods, 2023, 2201416. https://doi.org/10.1002/smtd.202201416
Enzyme-Instructed Peptide Assembly Favored by Preorganization for Cancer Cell Membrane Engineering, Yinghao Ding#, Debin Zheng#, Limin Xie, Xiangyang Zhang, Zhenghao Zhang, Ling Wang, Zhi-Wen Hu*, Zhimou Yang*, Journal of the American Chemical Society, 2023, 145 (8): 4366-4371 (select as front cover). https://doi.org/10.1021/jacs.2c11823
Dynamic responsiveness of self-assembling peptide-based nano-drug systems, Yuhan Wang, Jie Zhan, Jinyuan Wang, Zehong Chen, Zhimou Yang*, Jie Li*, Interdisciplinary Medicine, 2023,1, e202200. https://doi.org/10.1002/INMD.20220005
Seamless and early gap healing of osteochondral defects by autologous mosaicplasty combined with bioactive supramolecular nanofiber-enabled gelatin methacryloyl (BSN-GelMA) hydrogel, Hongwei Yu#, Yuna Shang#, Wei Sun#, Xinyi Ouyang, Wenyan Zhou, Jieji Lu, Shuhui Yang, Wei Wei, Xudong Yao, Xiaozhao Wang, Xianzhu Zhang, Yishan Chen, Qiulin He, Zhimou Yang*, Hongwei Ouyang*, Bioactive Materials, 2023, 19, 88-102. https://doi.org/10.1016/j.bioactmat.2022.03.038

2022年
Less is More: Preorganization Leads to Better Tumor Retention and Therapeutic Efficacy, Limin Xie, Yinghao Ding, Yuhan Wang, Xinxin Li, Zhimou Yang, Zhi-Wen Hu*, Advanced Functional Materials, 2022, 32, 2206969. https://doi.org/10.1002/adfm.202206969
An amelogenin-based peptide hydrogel promoted the odontogenic differentiation of human dental pulp cells, Xinxin Li, Zhaoxia Yu, Shihui Jiang, Xiaohua Dai, Guanghua Wang, Yue Wang, Zhimou Yang, Jie Gao*, Huiru Zou*, Regenerative Biomaterials, 2022, 9, rbac039. https://doi.org/10.1093/rb/rbac039
Supramolecular Nitric Oxide Depot for Hypoxic Tumor Vessel Normalization and Radiosensitization, Cuihong Yang, Ganen Mu, Ying Zhang, Yang Gao, Wenxue Zhang, Jinjian Liu, Wenwen Zhang, Paiyun Li, Lijun Yang, Zhimou Yang, Jie Gao*, Jianfeng Liu*, Advanced Materials, 2022, 34, 2202625. https://doi.org/10.1002/adma.202202625
Amino acid sequence determines the adjuvant potency of a d-tetra-peptide hydrogel, Yiming Zhang, Zhiwen Hu, Xinxin Li, Yinghao Ding, Zhenghao Zhang, Xiangyang Zhang, Wenting Zheng*, Zhimou Yang*, Biomaterials Science, 2022, 10, 3092-3098. https://doi.org/10.1039/D2BM00263A
PDGF-BB-derived supramolecular hydrogel for promoting skin wound healing, Ke Jian#, Chenghao Yang#, Tingting Li, Xia Wu, Jun Shen, Jiaying Wei, Zhimou Yang, Dan Yuan, Mingyi Zhao, Junfeng Shi*, Journal of Nanobiotechnology, 2022, 20 (1), 201. https://doi.org/10.1186%2Fs12951-022-01390-0
Enzyme-instructed self-assembly (EISA) assists the self-assembly and hydrogelation of hydrophobic peptides, Xinxin Li, Youzhi Wang, Yiming Zhang, Zhimou Yang, Jie Gao*, Yang Shi*, Journal of Materials Chemistry B, 2022, 10, 3242-3247. https://doi.org/10.1039/D2TB00182A
The protective effects of a D-tetra-peptide hydrogel adjuvant vaccine against H7N9 influenza virus in mice, Keda Chen#, Xiaoxin Wu#, Qingjing Wang, Ying Wang, Haiyan Zhang, Shuai Zhao, Chaonan Li, Zhiwen Hu, Zhimou Yang*, Lanjuan Li*, Chinese Chemical Letters, 2023, 34 (1), 107446. https://doi.org/10.1016/j.cclet.2022.04.044
Hypoxia-Responsive Molecular Probe Lighted up by Peptide Self-Assembly for Cancer Cell Imaging, Sifan Ai, Wenhao Dong, Jie Li*, Zhimou Yang*, Journal of Biomedical Nanotechnology, 2022, 18 (4), 1019-1027. https://doi.org/10.1166/jbn.2022.3304
A SupraGel for efficient production of cell spheroids, Sifan Ai, Hui Li, Hao Zheng, Jinming Liu, Jie Gao*, Jianfeng Liu*, Quan Chen*, Zhimou Yang*, Science China Materials, 2022, 65, 1655-1661. http://dx.doi.org/10.1007/s40843-021-1951-x
A supramolecular hydrogel based on the combination of YIGSR and RGD en- hances mesenchymal stem cells paracrine function via integrin α2β1 and PI3K/AKT signaling pathway for acute kidney injury therapy, Qiuxia Han#, Sifan Ai#, Quan Hong, Chuyue Zhang, Yanqi Song, Xiaochen Wang, Xu Wang, Shaoyuan Cui, Zongjin Li, Hanyu Zhu*, Zhimou Yang*, Xiangmei Chen, Guangyan Cai*, Chemical Engineering Journal, 2022, 436, 135088. https://doi.org/10.1016/j.cej.2022.135088
Naphthalenephenylalanine-phenylalanine-glycine-arginine-glycine-aspartic promotes self-assembly of nephron progenitor cells in decellularized scaffolds to construct bioengineered kidneys, Guangrui Geng#, Yunming Xiao#, Yuna Shang, Yingjie Zhang, Fei Zhu, Lifeng Tang, Fei Peng, Wanjun Shen, Yan Jin, Zhimou Yang*, Qinggang Li*, Xiangmei Chen*, Biomaterials Advances, 2022, 134, 112590, https://doi.org/10.1016/j.msec.2021.112590

2021年
Selective Degradation of PD-L1 in Cancer Cells by Enzyme-Instructed Self-Assembly, Yuhang Wang, Xinxin Li, Debin Zheng, Yumaio Chen, Zhenghao Zhang, Zhimou Yang*, Advanced Functional Materials, 2021, 31, 2102505. https://doi.org/10.1002/adfm.202102505
Hierarchical Nanostructured Electrospun Membrane with Periosteum-Mimic Microenvironment for Enhanced Bone Regeneration, Laijun Liu, Yuna Shang, Chaojing Li*, Yongjie Jiao, Yanchen Qiu, Chengyi Wang, Yuge Wu, Qiuyu Zhang, Fujun Wang*, Zhimou Yang*, Lu Wang*, Advanced Healthcare Materials, 2021, 10, 2101195. https://doi.org/10.1002/adhm.202101195
Enzyme-instructed self-assembly enabled fluorescence light-up for alkaline phosphatase detection, Yiming Zhang, Yinghao Ding, Xinxin Li, Zhenghao Zhang, Xiangyang Zhang, Yumiao Chen, Zhimou Yang, Yang Shi*, Zhi-Wen Hu*, Talanta, 2022, 239, 123078. https://doi.org/10.1016/j.talanta.2021.123078
Preorganization boosts the artificial esterase activity of a self-assembling peptide, Yaoxia Chen, Wenwen Zhang, Yinghao Ding, Chunhui Liang, Yang Shi, Zhi-Wen Hu, Ling Wang*, Zhimou Yang*, Science China Chemistry, 2021, 64, 1554-1559. http://dx.doi.org/10.1007/s11426-021-1029-x
Enzyme-instructed and mitochondria-targeting peptide self-assembly to efficiently induce immunogenic cell death, Debin Zheng, Jingfei Liu, Limin Xie, Yuhan Wang, Yinghao Ding, Rong Peng, Min Cui, Ling Wang, Yongjie Zhang*, Chunqiu Zhang*, Zhimou Yang*, Acta Pharmaceutica Sinica B, 2022, 12 (6), 2740-2750. https://doi.org/10.1016/j.apsb.2021.07.005
Organelle-inspired supramolecular nanomedicine to precisely abolish liver tumor growth and metastasis, Jie Zhan, Yuhan Wang, Shaodan Ma, Qin Qin, Ling Wang, Yanbin Cai*, Zhimou Yang*, Bioactive Materials, 2022, 9, 120-133. https://doi.org/10.1016/j.bioactmat.2021.07.021
Tandem Molecular Self-assembly for Selective Lung Cancer Therapy with Two Orders of Magnitude Increase in Efficiency, Debin Zheng, Jingfei Liu, Yinghao Ding, Limin Xie, Yingying Zhang, Yaoxia Chen, Rong Peng, Miao Cai, Ling Wang, Huaiming Wang*, Jie Gao*, Zhimou Yang*, Nanoscale, 2021, 13, 10891-10897. https://doi.org/10.1039/D1NR01174J
A Supramolecular “Trident” for Cancer Immunotherapy, Xinxin Li, Yuhan Wang, Yiming Zhang, Chunhui Liang, Zhenghao Zhang, Yaoxia Yang, Zhi-Wen Hu*, Zhimou Yang*, Advanced Functional Materials, 2021, 31, 2100729. http://dx.doi.org/10.1002/adfm.202100729
Supramolecular nanofibers with superior anti-angiogenesis and antitumor properties by enzyme-instructed self-assembly (EISA), Yaoxia Chen, Wenwen Zhang, Chuihui Liang, Debin Zheng, Yuhan Wang, Xiaoyang Li, Yang Shi, Fuqiang Wang*, Wenhao Dong*, Zhimou Yang*, Chemical Engineering Journal, 2021, 425, 130531. https://doi.org/10.1016/j.cej.2021.130531
An Insulin‐Inspired Supramolecular Hydrogel for Prevention of Type 1 Diabetes, Mohan Liu#, Zhongyan Wang#, Dandan Feng, Yuna Shang, Xinxin Li, Jianfeng Liu*, Zhimou Yang*, 2021, 8, 2003599. http://dx.doi.org/10.1002/advs.202003599
Peptide-based supramolecular hydrogels for local drug delivery, Zhenghao Zhang, Sifan Ai, Zhimou Yang, Xingyi Li, Advanced Drug Delivery, 2021, 174, 482-503. http://dx.doi.org/10.1016/j.addr.2021.05.010
Supramolecular Self‐Assembly‐Facilitated Aggregation of Tumor‐Specific Transmembrane Receptors for Signaling Activation and Converting Immunologically Cold to Hot Tumors, Jun Li, Yuan Fang, Yufan Zhang, Huaimin Wang, Zhimou Yang, Dan Ding*, Advanced Materials, 2021, 2008518. http://dx.doi.org/10.1002/adma.202008518
Supramolecular hydrogels of self-assembled zwitterionic-peptides, Yiming Zhang, Yinghao Ding, Xinxin Li, Debin Zheng, Jie Gao*, Zhimou Yang*, Chinese Chemical Letters, 2021, 32 (11), 3636-3640. https://doi.org/10.1016/j.cclet.2021.04.039
An injectable hydrogel to reverse the adverse microenvironment of diabetic infarcted heart, Si Chen, Xiaoxu Han, Yang Zou, Yuna Shang, Changjun Liu, Xin Jin, Yuan Li, Yuanning Lyu, Zhuodan Zhang, Zhimou Yang*, Wenguang Liu*, Wei Wang*, Materialia, 2021, 15, 100957. https://doi.org/10.1016/j.mtla.2020.100957
Targeting macrophage liver X receptors by hydrogel-encapsulated T0901317 reduces atherosclerosis without effect on hepatic lipogenesis, Chuanrui Ma, Ke Feng, Xiaoxiao Yang, Zhimou Yang, Yuna Shang, Guanwei Fan, Lipei Liu, Shu Yang, Xiaoju Li, Jihong Han, Yajun Duan*, Yuanli Chen*, British Journal of Pharmacology, 2021, 178, 1620-1638. http://dx.doi.org/10.1111/bph.15387
Dual-ligand supramolecular nanofibers inspired by the renin-angiotensin system for the targeting and synergistic therapy of myocardial infarction, Zhangpeng Wen#, Jie Zhan#, Hekai Li, Guanghui Xu, Shaodan Ma, Jianwu Zhang, Zehua Li, Caiwen Ou, Zhimou Yang*, Yanbin Cai*, Minsheng Chen*, Theranostics, 2021, 11(8), 3725-3741. http://dx.doi.org/10.7150/thno.53644
Enzyme-Instructed Self-Assembly Enabled Monomer-Excimer Transition to Construct Higher Ordered Luminescent Supramolecular Assembly for Activity-based Bioimaging, Yuanzhi Zhong, Jie Zhan*, Guanghui Xu, Yumiao Chen, Qin Qin, Xu Liao, Shaodan Ma, Zhimou Yang*, Yanbin Cai*, Angewandte Chemie International Edition, 2021, https://doi.org/10.1002/anie.202014278
Encapsulation of LXR ligand by D-Nap-GFFY hydrogel enhances anti-tumorigenic actions of LXR and removes LXR-induced lipogenesis, Ke Feng, Chuanrui Ma, Yuxin Liu, Xiaoxiao Yang, Zhimou Yang, Yaoxia Chen, Tengyan Xu, Chengbiao Yang, Shuang Zheng, Qi Li, Zhuo Wei, Dan Zhao, Peng Zeng, Jihong Han, Jie Gao*, Yuanli Chen*, Yajun Duan&, Theranostics, 2021, 11(6), 2634-2654. http://dx.doi.org/10.7150/thno.53139
PDGF-mimicking Supramolecular Nanofibers for Ionizing Radiation-induced Injury Repair, Yuna Shang, Hui Liu, Rong Peng, Chunhua Ren, Xin Luo, Chuanrui Ma, Yang Gao, Zhongyan Wang*, Jie Gao*, Jianfeng Liu*, Zhimou Yang*, Chemical Engineering Journal, 2021, 410, 128309. http://dx.doi.org/10.1016/j.cej.2020.128309

2020年
Pathway-dependent supramolecular polymerization of camptothecin derivatives into filaments for chemotherapy and imaging, Chunhui Liang, Yaoxia Chen, Debin Zheng, Tengyan Xu, Guojuan Pu, Yumiao Chen, Ling Wang*, Zhimou Yang*, Huaimin Wang*, Applied materials today, 2020, 21, 100855. https://doi.org/10.1016/j.apmt.2020.100787
Supramolecular Nanofibers Containing Arginine-Glycine-Aspartate (RGD) Peptides Boost Therapeutic Efficacy of Extracellular Vesicles in Kidney Repair, Chuyue Zhang, Yuna Shang, Xiaoiao Chen, Adam C. Midgley, Zhongyan Wang, Dashuai Zhu, Jie Wu, Pu Chen, Lingling Wu, Xu Wang, Kaiyue Zhang, Hongfeng Wang, Deling Kong, Zhimou Yang*, Zongjin Li*, Xiangmei CHen*, ACS Nano, 2020, 14 (9), 12133-12147. https://doi.org/10.1021/acsnano.0c05681
Old dog new tricks: PLGA microparticles as adjuvant for insulin peptide fragment induced immune tolerance against type 1 diabetes, Mohan Liu, Dandan Feng, Xiaoyu Liang, Min Li, Jing Yang, Hai Wang, Liyun Pang, Zhimin Zhou, Zhimou Yang, Deling Kong, Chen Li*, Molecular Pharmaceutics, 2020, 17(9), 3513-3525. https://doi.org/10.1021/acs.molpharmaceut.0c00525
An Ultrashort Peptide-Based Supramolecular Hydrogel Mimicking IGF-1 to Alleviate Glucocorticoid-Induced Sarcopenia, Yuna Shang#, Mingjie Kuang#, Zhonyan Wang, Ying Huang, Lulu Liu, Xige Zhao, Rui Zhang, Yanhong Zhao, Rong Peng, Shenghuan Sun, Qiang Yang*, Zhimou Yang*, ACS Applied Materials & Interfaces, 2020, 12, 34678-34688. https://doi.org/10.1021/acsami.0c09973
Nuclear delivery of dual anticancer drug-based nanomedicine constructed by cisplatinum-induced peptide self-assembly, Tengyan Xu, Chunhui Liang, Debin Zheng, Xiaorong Yan, Yaoxia Chen, Yumiao Chen, Xinxin Li, Yang Shi*, Ling Wang*, Zhimou Yang*, Nanoscale, 2020, 12, 15275-15282. https://doi.org/10.1039/D0NR00143K
Delivery of MSCs with a Hybrid β-Sheet Peptide Hydrogel Consisting IGF-1C Domain and D-Form Peptide for Acute Kidney Injury Therapy, International Journal of Nanomedicine, Hongfeng Wang#, Yuna Shang#, Xiaoniao Chen, Zhongyan Wang, Dashuai Zhu, Yue Liu, Chuyue Zhang, Pu Chen, Jie Wu, Lingling Wu, Deling Kong, Zhimou Yang*, Zongjin Li, Xiangmei Chen*, International Journal of Nanomedicine, 2020, 15, 4311-4324. http://dx.doi.org/10.2139/ssrn.3485132
Preorganization Increases the Self-Assembling Ability and Anti-tumor Efficacy of Peptide-Nanomedicine, Chunhui Liang, Zhongyan Wang, Tengyan Xu, Yaoxia Chen, Debin Zheng, Lushuai Zhang, Wenwen Zhang, Zhimou Yang, Yang Shi*, Jie Gao*, ACS Applied Materials & Interfaces, 2020, 12(20), 22492-22498. https://doi.org/10.1021/acsami.0c02572
β-galactosidase responsive AIE fluorogene for identification and removal of senescent cancer cells, Zhengfeng Gao, Heqi Gao, Debin Zheng, Tengyan Xu, Yaoxia Chen, Chunhui Liang, Ling Wang*, Dan Ding*, Zhimou Yang*, Science China Chemistry, 2020, 63, 398-403. http://dx.doi.org/10.1007/s11426-019-9659-2
Enzyme‐Instructed Self‐Assembly (EISA) and Hydrogelation of Peptides, Jie Gao, Jie Zhan, Zhimou Yang*, Advanced Materials, 2020, 32, 1805798. http://dx.doi.org/10.1002/adma.201805798
A strong CD8+ T cell-stimulating supramolecular hydrogel, Xinxin Li, Youzhi Wang, Siwan Wang, Chunhui Liang, Guojuan Pu, Yaoxia Chen, Ling Wang, Hua Xu*, Yang Shi*, Zhimou Yang*, Nanoscale, 2020,12, 2111-2117. https://doi.org/10.1039/C9NR08916K
Directional molecular sliding movement in peptide hydrogels accelerates cell proliferation, Shuxin Song, Jingyu Wang, Zhifei Cheng, Zhimou Yang, Linqi Shi, Zhilin Yu*, Nanoscale, 2020, 11, 1383-1393. https://doi.org/10.1039/C9SC05808G
A supramolecular protein chaperone for vaccine delivery, Zhongyan Wang, Yuna Shang, Zhaoqi Tan, Xiaoyan Li, Guoliang Li, Chunhua Ren*, Duqiang Wang*, Zhimou Yang, Jianfeng Liu*, Theranostics, 2020, 10(2), 657-670. http://dx.doi.org/10.7150/thno.39132

2019年
Tandem Molecular Self-Assembly Selectively Inhibits Lung Cancer Cells by Inducing Endoplasmic Reticulum Stress, Debin Zheng, Yumiao Chen, Sifan Ai, Renshu Zhang, Zhengfeng Gao, Chunhui Liang, Li Cao, Yaoxia Chen, Zhangyong Hong, Yang Shi, Ling Wang, Xingyi Li*, Zhimou Yang*, Research, 2019, 4, 1-11. http://dx.doi.org/10.34133/2019/4803624
Enhanced cellular uptake and nuclear accumulation of drug-peptide nanomedicines prepared by enzyme-instructed self-assembly, Chunhui Liang, Xiaorong Yan, Renshu Zhang, Tengyan Xu, Debing Zheng, Zhaoqi Zheng, Zhaoqi Tan, Yaoxia Chen, Zhengfeng Gao, Ling Wang, Xingyi Li*, Zhimou Yang*, Journal of Controlled Resease, 2020, 317, 109-117. https://doi.org/10.1016/j.jconrel.2019.11.028
A Supramolecular Hydrogel to Boost the Production of Antibodies for Phosphorylated Proteins, Youzhi Wang#, Xinxin Li#, Yiming Zhang, Ling Wang*, Zhimou Yang*, Chemical Communications, 2019, 55, 12388-12391. https://doi.org/10.1039/C9CC05633E
Selective pericellular hydrogelation by the overexpression of an enzyme and a membrane receptor, Yuhan Wang, Jie Zhan, Yumiao Chen, Sifan Ai, Liantao Li, Ling Wang, Yang Shi*, Junnian Zheng*, Zhimou Yang*, Chemical Communications, 2019, 11, 13714, 13719. https://doi.org/10.1039/C9NR04262H
β-Galactosidase Instructed Supramolecular Hydrogelation for Selective Identification and Removal of Senescent Cells, Tengyan Xu, Yanbin Cai, Xinglong Zhong, Le Zhang, Debing Zheng, Zhengfeng Gao, Xianmei Pan, Fuqiang Wang*, Minsheng Chen*, Zhimou Yang*, Chemical Communications, 2019, 55, 7175-7178. https://doi.org/10.1039/C9CC03056E
Supramolecular protein glue to boost enzyme activity, Yuna Shang, Yue Liao, Zhongju Ye, Zhongyan Wang, Lehui Xiao, Jie Gao*, Qigang Wang*, Zhimou Yang*, Science China Materials, 2019, 62, 1341-1349. http://dx.doi.org/10.1007/s40843-019-9425-6
A novel thermogel system of self-assembling peptides manipulated by enzymatic dephosphorylation, Yuna Shang, Zhongyan Wang, Renshu Zhang, Xinxin Li, Shuhao Zhang, Jie Gao, Xingyi Li*, Zhimou Yang*, Chemical Communications, 2019, 55, 5123-5126. https://doi.org/10.1039/C9CC00401G
Supramolecular Nanofibers with Superior Bioactivity to IGF-1, Yuna Shang#, Deke Zhi#, Guowei Feng, Zhongyan Wang, Duo Mao, Shuang Guo, Ruihua Liu, Lulu Liu, Shuhao Zhang, Shenghuan Sun, Kai Wang*, Deling Kong, Jie Gao*, Zhimou Yang*, Nano Letters, 2019, 19(3), 1560-1569. https://doi.org/10.1021/acs.nanolett.8b04406

2018年
Responsive peptide-based supramolecular hydrogels constructed by self-immolative chemistry, Debin Zheng, Zhengfeng Gao, Tengyan Xu, Chunhui Liang, Yang Shi*, Ling Wang*, Zhimou Yang*, Nanoscale, 2018, 10, 21459-21465. https://doi.org/10.1039/C8NR07534D
Supramolecular Nanofibers of Drug‐Peptide Amphiphile and Affibody Suppress HER2+ Tumor Growth, Chunhui Liang, Lushuai Zhang, Wene Zhao, Linlin Xu, Yaoxia Chen, Jiafu Long, Fuqiang Wang*, Ling Wang*, Zhimou Yang*, Advanced Healthcare Materials, 2018, 7, 1800899. https://doi.org/10.1002/adhm.201800899
A Supramolecular Hydrogel for Spatial-Temporal Release of Auxin to Promote Plant Root Growth, Yaoxia Chen, XInjing Li, Jing Bai, Fang Shi, Tengyan Xu, Qingqiu Gong*, Zhimou Yang*, Chemical Communications, 2018, 54, 11721-11724. https://doi.org/10.1039/C8CC05999C
Fast Naked-eye Detection of Zinc Ion by Molecular Assembly-assisted Polymerization of Diacetylene, Yiming Zhang#, Yu-Chen Pan#, Youzhi Wang, Dong-Sheng Guo*, Jie Gao*, Zhimou Yang*, Nanoscale, 2018, 10, 18829-18834. https://doi.org/10.1039/C8NR05578E
Bifunctional Supramolecular Hydrogel Alleviates Myocardial Ischemia/Reperfusion Injury by Inhibiting Autophagy and Apoptosis, Yi Deng#, Guoqin Chen#, Min Ye, Yingyan He, Zehua Li, Xianbao Wang, Caiwen Ou*, Zhimou Yang*, Minsheng Chen*, Journal of Biomedical Nanotechnology, 2018, 14(8), 1458-1470. https://doi.org/10.1166/jbn.2018.2582
Folic Acid-Derived Hydrogel Enhances the Survival and Promotes Therapeutic Efficacy of iPS Cells for Acute Myocardial Infarction, Hekai Li, Jie Gao, Yuna Shang, Yongquan Hua, Min Ye, Zhimou Yang*, Caiwen Ou*, Minsheng Chen*, ACS Applied Materials & Interfaces, 2018, 10(29), 24459-24468. https://doi.org/10.1021/acsami.8b08659
An aldehyde-terminal peptide-based supramolecular hydrogel for controlled delivery of amine drugs, Youzhi Wang, Yiming Zhang, Xinxin Li, Can Li, Zhimou Yang*, Ling Wang*, 2018, 13, 3460-3463. http://dx.doi.org/10.1002/asia.201800708
Anticancer Supramolecular Hydrogel of D/L-Peptide with Enhanced Stability and Bioactivity, Chunhua Ren, Yang Gao, Jinjian Liu, Yumin Zhang, Guojuan Pu, Lijun Yang, Fan Huang, Cuihong Yang, Zhimou Yang*, Jianfeng Liu*, Journal of Biomedical Nanotechnology, 2018, 14(6), 1125-1134. https://doi.org/10.1166/jbn.2018.2564
Supramolecular Nanofibers of Curcumin for Highly Amplified Radiosensitization of Colorectal Cancers to Ionizing Radiation, Huae Xu, Tingting Wang, Chengbiao Yang, Xiaolin Li*, Guan Liu, Zhimou Yang, Pankaj Kumar Singh, Sunil Krishnan*, Dan Ding*, Advanced Functional Materials, 2018, 28, 1707140. http://dx.doi.org/10.1002/adfm.201707140
Narrowing the diversification of supramolecular assemblies by preorganization, Zhongyan Wang#, Chunhui Liang#, Yuna Shang, Shuangshuang He, Ling Wang, Zhimou Yang*, Chemical Communications, 2018, 54, 2751-2754. https://doi.org/10.1039/C8CC01082J
Kinetic Control over Supramolecular Hydrogelation and Anticancer Property of Taxol, Xiaoli Zhang, Youzhi Wang, Yongquan Hua, Jinyou Duan, Minsheng Chen, Ling Wang, Zhimou Yang*, Chemical Communications, 2018, 54, 755-758. https://doi.org/10.1039/C7CC08041G
Tandem Molecular Self‐Assembly in Liver Cancer Cells, Jie Zhan, Yanbin Cai, Shuangshuang He, Ling Wang, Zhimou Yang*, Angewandte Chemie International Edition, 2018, 57, 1813-1816. http://dx.doi.org/10.1002/anie.201710237

2017年
Cancer vaccines using supramolecular hydrogels of NSAID-modified peptides as adjuvants abolish tumorigenesis, Zhongyan Wang, Chunhui Liang, Fang Shi, Tao He, Changyang Gong, Ling Wang, Zhimou Yang*, Nanoscale, 2017, 9, 14058-14064. https://doi.org/10.1039/C7NR04990K
Single Dose of Protein Vaccine with Peptide Nanofibers As Adjuvants Elicits Long-Lasting Antibody Titer, Chengbiao Yang, Fang Shi, Can Li, Youzhi Wang, Ling Wang*, Zhimou Yang*, ACS Biomaterials Science & Engineering, 2018, 4(6), 2000-2006. https://doi.org/10.1021/acsbiomaterials.7b00488
Enzyme-assisted peptide folding, assembly and anti-cancer properties, Chunhui Liang, Debin Zheng, Fang Shi, Tengyan Xu, Cuihong Yang, Jianfeng Liu, Ling Wang*, Zhimou Yang*, Nanoscale, 9, 11987-11993. https://doi.org/10.1039/C7NR04370H
Potentiating Immune Response of MUC1-based Antitumor Vaccine Using Peptide-Based Nanovector as a Promising Vaccine Adjuvant, Yonghui Liu, Youzhi Wang, Fan Yu, Zhenqing Zhang, Zhimou Yang, Wenpeng Zhang*, Peng George Wang, Wei Zhao*, Chemical Comumunications, 2017, 53, 9486-9489. https://doi.org/10.1039/C7CC04386D
A Mixed Component Supramolecular Hydrogel to Improve Mice Cardiac Function and Alleviate Ventricular Remodeling after Acute Myocardial Infarction, Guoqin Chen, Jinliang Li, Mingcai Song, Zhiye Wu, Wenzhu Zhang, Zhongyan Wang, Jie Gao*, Zhimou Yang*, Caiwen Ou*, Advanced Functional Materials, 2017, 27, 1701798. http://dx.doi.org/10.1002/adfm.201701798
Supramolecular silk from a peptide hydrogel, Jie Zhan, Yanbin Cai, Shenglu Ji, Yuna Shang, Jie Gao*, Zhimou Yang*, Materials Chemistry Frontiers, 2017, 1, 911-915. https://doi.org/10.1039/C6QM00233A
Supramolecular Hydrogels of Indole-Capped Short Peptides as Vaccine Adjuvants, Zhongyan Wang, Yanbin Cai, Linan Yi, Jie Gao*, Zhimou Yang*, Chinese Journal of Chemistry, 2017, 35, 1057-1062. http://dx.doi.org/10.1002/cjoc.201600813
A Glycyrrhetinic Acid-Modified Curcumin Supramolecular Hydrogel for liver tumor targeting therapy, Guoqin Chen, Jinliang Li, Yanbin Cai, Jie Zhan, Jie Gao, Mingcai Song*, Yang Shi*, Zhimou Yang, Scientific Reports, 2017, 7, 44210. http://dx.doi.org/10.1038/srep44210
Spatiotemporal Control of Supramolecular Self-Assembly and Function, Jie Zhan, Yanbin Cai, Shenglu Ji, Shuangshuang He, Yi Cao, Dan Ding, Ling Wang, Zhimou Yang*, ACS Applied Materials & Interfaces, 2017, 9(11), 10012-10018. https://doi.org/10.1021/acsami.7b00784
In situ generated D‐peptidic nanofibrils as multifaceted apoptotic inducers to target cancer cells, Xuewen Du, Jie Zhou, Huainin Wang, Junfeng Shi, Yi Kuang, Wu Zeng, Zhimou Yang, Bing Xu*, Cell Death & Disease, 2017, 8, e2614. http://dx.doi.org/10.1038/cddis.2016.466
Supramolecular ‘Trojan Horse’ for Nuclear Delivery of Dual Anticancer Drugs, Yanbin Cai, Haosheng Shen, Jie Zhan, Mingliang Lin, Liuhan Dai, Chunhua Ren, Yang Shi, Jianfeng Liu*, Jie Gao*, Zhimou Yang*, Journal of the American Chemistry, 2017, 139(8), 2876-2879. https://doi.org/10.1021/jacs.6b12322 Selectively Inducing Cancer Cell Death by Intracellular Enzyme-Instructed Self-Assembly (EISA) of Dipeptide Derivatives, Jie Li, Junfeng Shi, Jamie E. Medina, Jie Zhou, Xuewen Du, Huaimin Wang, Cuihong Yang, Jianfeng Liu, Zhimou Yang, Daniela M. Dinulescu*, Bing Xu*, Advanced Healthcare Materials, 2017, 6, 16001400, http://dx.doi.org/10.1002/adhm.201601400
Gd(III)-induced Supramolecular Hydrogelation with Enhanced Magnetic Resonance Performance for Enzyme Detection, Yongquan Hua, Guojuan Pu, Caiwen Ou, Xiaoli Zhang, Ling Wang, Jiangtao Sun*, Zhimou Yang*, Minsheng Chen*, Scientific Reports, 2017, 7, 40172. http://dx.doi.org/10.1038/srep40172