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成果及论文
  1. Xu Y, Ruggero D. A tRF nucleator for Nucleolin in cancer metastasis. Mol Cell. 2022; 82(14): 2536–2538.

  2. Xu Y, Huang P, Wang Y, Xue L, Devericks E, Nguyen H, Yu X, Oses-Prieto J, Burlingame A, Miglani S, Goodarzi H, Ruggero D. ERα is a non-canonical RNA binding protein sustaining tumor cell survival and drug resistance. Cell 2021; 184, 5215–5229 

    Cell专题评述https://doi.org/10.1016/j.cell.2021.09.012

  3. Wang Y; Li X; Ge J; Liu M; Pang X; Liu J; Luo C; Xu Y*; Zhao Q*. The methyltransferase PRMT1 regulates γ-globin translation. J. Biol Chem. 2021; 296 10047. *= 共通讯 

  4. Kovalski J#*Xu Y#*, Ruggero D*. Examining Myc-Dependent Translation Changes in Cellular Homeostasis and Cancer. The Myc Gene: Methods and Protocols, Second Edition. Springer; ISBN: 1071614754. *= 共通讯 

  5. Xu Y; Ruggero D*. The role of translation control in tumorigenesis and its therapeutic implications. Annu. Rev. Cancer Biol. 2020; 4:437-57.

  6. Wei J, Wang YH, Lee CY, Truillet C, Oh DY, Xu Y, Ruggero D, Flavell RR, VanBrocklin HF, Seo Y, Craik CS, Fong L, Wang CI, Evans MJ. An Analysis of Isoclonal Antibody Formats Suggests a Role for Measuring PD-L1 with Low Molecular Weight PET Radiotracers. Mol Imaging Biol. 2020; 22(6):1553-1561.

  7. Xu Y#, Poggio M#, Jin HY, Shi Z, Forester CM, Wang Y, Stumpf CR, ..., Ruggero D. Translation control of the immune checkpoint in cancer and its therapeutic targeting. Nat. Med. 2019; 25(2):301-311. 

    F1000 Prime二度推荐,评价分别为Exceptional和Very Good 

    NCI Newshttps://www.cancer.gov/news-events/cancer-currents-blog/2019/translation-inhibitor-immune-checkpoint-protein 

    Cancer Discovery 2019; 9: 317       

  8. Fish L, Navickas A, Culbertson, B, Xu Y, Nguyen HCB, Zhang S, Hochman M, Okimoto R, Dill BD, Molina H, Najafabadi HS, Claudio Alarcón, Ruggero D, Goodarzi H. Nuclear TARBP2 drives oncogenic dysregulation of RNA splicing and decay. Mol Cell 2019; 5;75(5):967-981.e9 

  9. Xu Y, Zhang H, Nguyen V, Angelopoulos N, Nunes J, Reid A, Buluwela L, Magnani L, Stebbing J, Giamas G. LMTK3 Represses Tumour Suppressor-Like Genes through Chromatin Remodeling in Breast Cancer. Cell Rep. 2015; 4;12(5):837-49.

  10. Xu Y, Zhang H, Lit LC, Grothey A, Athanasiadou M, Kiritsi M, Lombardo Y, Frampton AE, Green AR, Ellis IO, Ali S, Lenz HJ, Thanou M, Stebbing J and Giamas G. The kinase LMTK3 promotes invasion in breast cancer through GRB2-mediated induction of integrin beta(1). Sci Signal. 2014; 7(330):ra58.

  11. Zhang H#Xu Y#, Papanastasopoulos P, Stebbing J, Giamas G. Broader implications of SILAC-based proteomics for dissecting signaling dynamics in cancer. Expert Rev Proteomics. 2014 Dec;11(6):713-31.  

  12. Xu Y, Zhang H and Giamas G. Targeting lemurs against cancer metastasis. Oncotarget. 2014; 5(14):5192-5193.

  13. Liu TY, Huang HH, Wheeler D, Xu Y, Wells JA, Song YS, Wiita AP. Time-Resolved Proteomics Extends Ribosome Profiling-Based Measurements of Protein Synthesis Dynamics. Cell Syst. 2017 Jun 28;4(6):636-644.e9. 

  14. Stebbing J, Zhang H, Xu Y, Grothey A, Ajuh P, Angelopoulos N, Giamas G. Characterization of the Tyrosine Kinase-Regulated Proteome in Breast Cancer by Combined use of RNA interference (RNAi) and Stable Isotope Labeling with Amino Acids in Cell Culture (SILAC) Quantitative Proteomics. Mol Cell Proteomics. 2015; 14(9):2479-92. 

  15. Stebbing J, Zhang H, Xu Y, Lit LC, Green AR, Grothey A, Lombardo Y, Periyasamy M, Blighe K, Zhang W, Shaw JA, Ellis IO, Lenz HJ, Giamas G. KSR1 regulates BRCA1 degradation and inhibits breast cancer growth. Oncogene. 2015; 16;34(16):2103-14.

  16. Zhang H, Angelopoulos N, Xu Y, Grothey A, Nunes J, Stebbing J, Giamas G. Proteomic profile of KSR1-regulated signaling in response to genotoxic agents in breast cancer. Breast Cancer Res Treat. 2015; 151(3): 555-68. 

  17. Stebbing J, Filipovic A, Lit LC, Blighe K, Grothey A, Xu Y, Miki Y, Chow LW, Coombes RC, Sasano H, Shaw JA and Giamas G. LMTK3 is implicated in endocrine resistance via multiple signaling pathways. Oncogene. 2013; 32(28):3371-3380. 

  18. Zhang H, Xu Y, Filipovic A, Lit LC, Koo CY, Stebbing J and Giamas G. SILAC-based phosphoproteomics reveals an inhibitory role of KSR1 in p53 transcriptional activity via modulation of DBC1. Br J Cancer. 2013; 109(10):2675-2684. 

  19. Xu H, Wei Y, Zhang Y, Xu Y, Li F, Liu J, Zhang W, Han X, Tan R and Shen P. Oestrogen attenuates tumour progression in hepatocellular carcinoma. J Pathol. 2012; 228(2):216-229. 

  20. Yang W, Lu Y, Xu Y, Xu L, Zheng W, Wu Y, Li L and Shen P. Estrogen represses hepatocellular carcinoma (HCC) growth via inhibiting alternative activation of tumor-associated macrophages (TAMs). J Biol Chem. 2012; 287(48):40140-40149.

  21. Angelopoulos N, Stebbing J, Xu Y, Giamas G Zhang H. Proteomic profile of KSR1-regulated signaling in response to genotoxic agents in breast cancer. Data in Brief. 2016; 7: 740-746.