代表性论文：

1. Min Li, Yinan Zhao, Jiao Sun, Huiying Chen, Zhanbiao Liu, Kexin Lin, Pengfei Ma, Wenjun Zhang, Yuhong Zhen, Shufen Zhang, Shubiao Zhang*. pH/Reduction Dual-responsive Hyaluronic Acid-podophyllotoxin Prodrug Micelles for Tumor Targeted Delivery. Carbohydrate Polymers, 2022, 288: 119402

2. Rui Wang, Yang Xuan, Yinan Zhao, Wei Wang, Pengfei Ma, Benzhi Ju, Yuhong Zhen, Shubiao Zhang*. Cationic Nanoparticulate System for Codelivery of MicroRNA-424 and Podophyllotoxin as a Multimodal Anticancer Therapy. Molecular Pharmaceutics, 2022, 19, 2092-2104

3. Yang Xuan, Yating Gao, Meng Guan, Shubiao Zhang*. Application of ‘Smart’ Multifunctional Nanoprobes in Tumor Diagnosis and Treatment. Journal of Materials Chemistry B, 2022, 10, 3601  

4. Meng Guan, Yang Xuan, Yating Gao, Yining Liu, Shubiao Zhang*. Synthesis of Ag@GQD and Their Application in Photoacoustic Imaging and Chemical/photothermal Combination Therapy and Bacteriostasis. Journal of Materials Science, 2022, 57: 7056-7067  

5. Yu Zou, Yuhong Zhen, Yinan Zhao, Huiying Chen, Rui Wang, Wei Wang, Pengfei Ma, Defu Zhi, Benzhi Ju, Shubiao Zhang*. pH-Sensitive, Tail-modified, Ester-linked Ionizable Cationic Lipids for Gene Delivery. Biomaterials Advances, 2022,139: 12984

6. Lingyu Han, Jiao Sun, Peter A. W., Jixin Yang, Shubiao Zhang*. Octenyl-succinylated inulins for the delivery of hydrophobic drug, International Journal of Biological Macromolecules, 2022, 221: 1112-1120

7. Rui Wang, Yinan Zhao, Zhenlong Huang, Yaxin Zhou, Wei Wang, Yang Xuan, Yuhong Zhen, Benzhi Ju,* Shutao Guo,* and Shubiao Zhang*. Self-Assembly of Podophyllotoxin-Loaded Lipid Bilayer Nanoparticles for Highly Effective Chemotherapy and Immunotherapy via Downregulation of Programmed Cell Death Ligand 1 Production. ACS Nano, 2022, 16: 3943−3954

8. Yu Zou, Quan Zhou, Yinan Zhao, Defu Zhi, Huiying Chen, Rui Wang, Benzhi Ju, Shubiao Zhang*. Structure-Activity Relationships of pH-Responsive and Ionizable Lipids for Gene Delivery. International Journal of Pharmaceutics, 2022, 617: 121596  

9. Min Li , Ling'e Zhang, Yang Xuan, Defu Zhi , Wei Wang, Wenjun Zhang, Yinan Zhao, Shufen Zhang, Shubiao Zhang*. pH-Sensitive Hyaluronic Acid-Targeted Prodrug Micelles Constructed via a One-Step Reaction for Enhanced Chemotherapy. International Journal of Biological Macromolecules, 2022, 206: 489-500 

10. Jiao Sun, Lingyu Han, Shubiao Zhang*. Hyaluronic Acid Prodrug Micelles for Tumour Therapy. Journal of Drug Targeting, 2022, 30(1): 22-30.   

11. Yinan Zhao, Tianyi Zhao, Yingnan Cao, Jiao Sun, Quan Zhou, Huiying Chen, Shutao Guo, Yifeng Wang, Yuhong Zhen, Xingjie Liang, Shubiao Zhang*. Temperature-Sensitive Lipid-Coated Carbon Nanotubes for Synergistic Photothermal Therapy and Gene Therapy. ACS Nano, 2021, 15 (4), 6517-6529.

12. Yang Xuan, Meng Guan, Shubiao Zhang*.Tumor Immunotherapy and Multi-Mode Therapies Mediated by Medical Imaging of Nanoprobes. Theranostics, 2021, 11 (15), 7360-7378.

13. Yang Xu, Ziqi Chen, Zunkai Xu, Yanyan Du, Jianghao Han, Xiaoyong Yuan, Shubiao Zhang, Shutao Guo. Intra-Articular Injection of Acid-Sensitive Stearoxyl-Ketal-Dexamethasone Microcrystals for Long-Acting Arthritis Therapy. Asian Journal of Pharmaceutical Sciences, 2021, 16 (2), 213-221.

14. Ze Liang, Linying Du, Enxia Zhang, Yinan Zhao, Wei Wang, Pengfei Ma,  Meng yuan Dai, Qi Zhao, Hong Xu, Shubiao Zhang, Yuhong Zhen. Targeted-Delivery of Sirna Via a Polypeptide-Modified Liposome for the Treatment of Gp96 Over-Expressed Breast Cancer. Materials Science & Engineering C-Materials for Biological Applications, 2021, 121, 111847.

15. Min Li, Yinan Zhao, Wenjun Zhang, Shufen Zhang, Shubiao Zhang*. Multiple-Therapy Strategies Via Polysaccharides-Based Nano-Systems in Fighting Cancer. Carbohydrate Polymers, 2021, 269, 118323.

16. Min Li, Jiao Sun, Wenjun Zhang, Yinan Zhao, Shufen Zhang, Shubiao Zhang*. Drug Delivery Systems Based on Cd44-Targeted Glycosaminoglycans for Cancer Therapy. Carbohydrate Polymers, 2021, 251, 117103.

17. Mengke Jia, Haina Hu, Xiaoqing Xiong, Lihua Lyu, Hongjuan Zhao, Shubiao Zhang*, Jun Hou. Investigation on the Construction, Photophysical Properties and Dyeing Mechanism of 1,8-Naphthalimide-Based Fluorescent Dyes Suitable for Dyeing Wool Fibers in Supercritical CO2. Dyes And Pigments, 2021, 190, 109343.

18. Defu Zhi, Ting Yang, Tingyu Zhang, Mei Yang, Shubiao Zhang*, Ryan F Donnelly. Microneedles for Gene and Drug Delivery in Skin Cancer Therapy. Journal of Controlled Release, 2021, 335, 158-177.

19. Shuang Fu, Yinan Zhao, Jiao Sun,YTin gang, Defu Zhi, Enxia Zhang, Fangli Zhong,Yuhong Zhen, Shufen Zhang, Shubiao Zhang*. Integrin Alphavbeta3-Targeted Liposomal Drug Delivery System for Enhanced Lung Cancer Therapy. Colloids and Surfaces B-Biointerfaces, 2021, 201, 111623.

20. Ze Liang, Linying Du, Enxia Zhang, Yinan Zhao, Wei Wang, Pengfei Ma, Mengyuan Dai, Qi Zhao, Hong Xu, Shubiao Zhang*, Yuhong Zhen*. Targeted-Delivery of Sirna Via a Polypeptide-Modified Liposome for the Treatment of Gp96 Over-Expressed Breast Cancer. Materials Science & Engineering C-Materials for Biological Applications, 2021, 121: 111847.

代表性科研奖励：

1.《转基因产品微流控芯片筛查与新品系鉴定关键技术及标准化应用》，辽宁省科学技术进步奖二等奖，2022年；

2. 《新型阳离子脂质及基因递送研究》，辽宁省自然科学二等奖，2021年。

代表性科研项目：

1. 国家重点研发计划，农食产品质量控制及分级国际标准研究，280万；

2. 国家自然科学基金青年基金项目，典型纳米粒子的细胞毒性及其与信号通路蛋白作用机制研究，24万；

3. 辽宁省民生科技计划项目，新型siRNA递送系统的创制，20万；

4. 大连市科技创新基金项目，基于新冠病毒的mRNA疫苗构建及其免疫反应研究，50万。