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成果及论文

* Corresponding Author.  These authors contributed equally to this work.


2023

28. Meng Jia, Liang Li, Ruiqi Chen, Junyao Du, Zhe Qiao, Di Zhou, Min Liu, Xiaojie Wang, Jichao Wu, Yusheng Xie, Yu Sun, Yan Zhang, Ziying Wang, Tao Zhang, Huili Hu, Jinpeng Sun, Wei Tang, Fan Yi. Targeting RNA oxidation by ISG20-mediated degradation is a potential therapeutic strategy for acute kidney injury. Molecular Therapy, 2023, 31, 3034-3051.

27. Jie Liu, Shubhadip Mallick, Yusheng Xie, Corentin Grassin, Belén Lucas, Beate Schölermann, Axel Pahl, Rebecca Scheel, Carsten Strohmann, Christoph Protzel, Thorsten Berg, Christian Merten, Slava Ziegler, Herbert Waldmann. Morphological profiling identifies the motor protein Eg5 as cellular target of spirooxindoles. Angewandte Chemie, 2023, 135, e202301955

2022

26. Beate Schölermann, Jana Bonowski, Michael Grigalunas, Annina Burhop, Yusheng Xie, Joseph GF Hoock, Jie Liu, Mark Dow, Adam Nelson, Christine Nowak, Axel Pahl, Sonja Sievers, Slava Ziegler. Identification of Dihydroorotate Dehydrogenase Inhibitors Using the Cell Painting Assay. ChemBioChem, 2022, 23, e202200475.

25. Kaiqi Long, Yang Yang, Zhanfeng Du, Weirong Kang, Wen Lv, Yafei Li, Yusheng Xie, Hongyan Sun, Changyou Zhan, Weiping Wang. H2S-Responsive Small-Molecule Nanocarriers for Drug Delivery to Colorectal Tumors. Advanced Therapeutics. 2022, 5, 2200044.

24. Xiaoyang Cui, Enhua Shi, Jing Li, Yujia Li, Zhe Qiao, Ziying Wang, Min Liu, Wei Tang, Yu Sun, Yan Zhang, Yusheng Xie, Junhui Zhen, Xiaojie Wang, Fan Yi. GPR87 promotes renal tubulointerstitial fibrosis by accelerating glycolysis and mitochondrial injury. Free Radical Biology and Medicine. 2022, 189, 58-70.

23. Liang Li, Wei Tang, Yan Zhang, Meng Jia, Limei Wang, Quanxin Li, Qingsheng Han, Xiuping Peng, Yusheng Xie, Jichao Wu, Ziying Wang, Junhui Zhen, Xiaojie Wang, Min Liu, Yu Sun, Chun Zhang, Fan Yi. Targeting tissue-resident memory CD8+ T cells in the kidney is a potential therapeutic strategy to ameliorate podocyte injury and glomerulosclerosis. Molecular Therapy, 2022, 30, 2746 – 2759.

22. Wei Huang, Bi-Ou Wang, Yun-Feng Hou, Yi Fu, Si-Jia Cui, Jing-Han Zhu, Xin-Yu Zhan, Rong-Kun Li, Wei Tang, Ji-Chao Wu, Zi-Ying Wang, Mei Wang, Xiao-Jie Wang, Yan Zhang, Min Liu, Yu-Sheng Xie, Yu Sun, Fan Yi. JAML promotes acute kidney injury mainly through a macrophage-dependent mechanism. JCI Insight. 2022;7(14):e158571.

21. Xie, Y.; Shubo Du; Zhiyang Liu; Min Liu; Zhiqiang Xu; Xiaojie Wang; Jia Xuan Kee; Fan Yi;* Hongyan Sun;* Shao Q. Yao* Chemical biology tools for protein lysine acylation. Angew. Chem., Int. Ed. 2022, 61, e202200303 (IF: 15.336)

20. Hui, C.; Wang, Z.; Xie, Y.;* Liu, J.* Contemporary synthesis of bioactive cyclobutane natural products. Green Synthesis and Catalysis. 2022, https://doi.org/10.1016/j.gresc.2022.04.006.

2021

21.    Yang, L.; † Chen, S.; † Yi, D.; Chen, Q.; Zhang, J.; Xie, Y.;* Sun, H.* Synthesis and fluorescence properties of red to near-infrared emitting push-pull dyes based on benzodioxazole scaffolds. Journal of Materials Chemistry B 2021, DOI: 10.1039/D1TB01189H

20.    Yang, L.; Xie, Y.;* Chen, Q.; Zhang, J.; Li, L.; Sun, H.* Colorimetric and Fluorescent Dual-Signal Chemosensor for Lysine and Arginine and Its Application to Detect Amines in Solid-Phase Peptide Synthesis. ACS Applied Bio Materials 2021, 4 (8), 6558-6564.

19.    Wang, Z.; Hui, C.; Xie, Y. Natural STAT3 inhibitors: A mini perspective. Bioorganic chemistry 2021, 115, 105169.

 

Before SDU

2021

      18.    Chemical Probes And Methods of Use Thereof. US 17/371,177

      17.    Compound And A Method for Identifying A Protein Using Said Compound. US 17/350,934

16.    Feng, L.; Wang, P.; Feng, Y.; Zhang, J.; Chen, Q.; Xie, Y.; Luo, J.; Xia, J.; Yao, S. Q.; Sun, H. A reversible microarray immobilization strategy based on thiol-quinone reaction. Chinese Chemical Letters 2021.

15.    Yang, L.; Chen, Q.; Gan, S.; Guo, Q.; Zhang, J.; Zhang, H.; Xie, Y.; Xiao, H.; Wang, W.; Sun, H. An activatable AIEgen probe for in-situ monitoring and long-term tracking of ferrous ions in living cells. Dyes Pigm. 2021, 190, 109271.

14.    Xie, Y.; Zhang, J.; Yang, L.; Chen, Q.; Hao, Q.; Zhang, L.; Sun, H.. A dual-function chemical probe for detecting erasers of lysine lipoylation. Front. Chem. Sci. Eng., 2021, DOI: 10.1007/s11705-021-2051-0

13.    Xie, Y.; Yang, L.; Chen, Q.; Zhang, J.; Feng, L.; Chen, J. L.; Hao, Q.; Zhang, L.; Sun, H. Single-step fluorescent probes to detect decrotonylation activity of HDACs through intramolecular reactions. Eur. J. Med. Chem. 2021, 212, 113120.

 

2020

12.    Chen, Q.; Cheng, K.; Wang, W.; Yang, L.; Xie, Y.; Feng, L.; Zhang, J.; Zhang, H.; Sun, H. A pyrene-based ratiometric fluorescent probe with a large Stokes shift for selective detection of hydrogen peroxide in living cells. Journal of Pharmaceutical Analysis 2020, 10 (5), 490-497.

11.    Feng, L.; Xie, Y.;* Au-Yeung, S. K.; Hailu, H. B.; Liu, Z.; Chen, Q.; Zhang, J.; Pang, Q.; Yao, X.; Yang, M.; Zhang, L.; Sun, H. A fluorescent molecular rotor probe for tracking plasma membranes and exosomes in living cells. Chem. Commun. 2020, 56 (60), 8480-8483.

 

2019

10.    Xie, Y.; Chen, L.; Wang, R.; Wang, J.; Li, J.; Xu, W.; Li, Y.; Yao, S. Q.; Zhang, L.; Hao, Q.; Sun, H. Chemical Probes Reveal Sirt2’s New Function as a Robust “Eraser” of Lysine Lipoylation. J. Am. Chem. Soc. 2019, 141 (46), 18428-18436.

 

2018

9.       Lan, M.; Zhao, S.; Xie, Y.; Zhao, J.; Guo, L.; Niu, G.; Li, Y.; Sun, H.; Zhang, H.; Liu, W.; Zhang, J.; Wang, P.; Zhang, W. Water-Soluble Polythiophene for Two-Photon Excitation Fluorescence Imaging and Photodynamic Therapy of Cancer. ACS Appl. Mater. Interfaces 2017, 9 (17), 14590-14595.

 

2016

8.       Xie, Y.; Ge, J.; Lei, H.; Peng, B.; Zhang, H.; Wang, D.; Pan, S.; Chen, G.; Chen, L.; Wang, Y.; Hao, Q.; Yao, S. Q.; Sun, H. Fluorescent Probes for Single-Step Detection and Proteomic Profiling of Histone Deacetylases. J Am Chem Soc 2016, 138 (48), 15596-15604.

7.       Chen, G.; Xie, Y.; Peltier, R.; Lei, H.; Wang, P.; Chen, J.; Hu, Y.; Wang, F.; Yao, X.; Sun, H. Peptide-Decorated Gold Nanoparticles as Functional Nano-Capping Agent of Mesoporous Silica Container for Targeting Drug Delivery. ACS Appl. Mater. Interfaces 2016, 8 (18), 11204-9.

 

2015

6.       Zhang, H.; Xie, Y.; Wang, P.; Chen, G.; Liu, R.; Lam, Y. W.; Hu, Y.; Zhu, Q.; Sun, H. An iminocoumarin benzothiazole-based fluorescent probe for imaging hydrogen sulfide in living cells. Talanta 2015, 135, 149-54.

 

2014

5.       Li, X.; Zhang, H.; Xie, Y.; Hu, Y.; Sun, H.; Zhu, Q. Fluorescent probes for detecting monoamine oxidase activity and cell imaging. Org. Biomol. Chem. 2014, 12 (13), 2033-2036.

4.       Chen, G.; Xie, Y.; Zhang, H.; Wang, P.; Cheung, H.-Y.; Yang, M.; Sun, H. A general colorimetric method for detecting protease activity based on peptide-induced gold nanoparticle aggregation. RSC Adv. 2014, 4 (13), 6560.

 

2012-2010

3.       Li, Y.; * Liu, J.; Xie, Y.; Zhang, R.; Jin, K.; Wang, X.; Duan, C. Nickel-catalyzed C-H direct amination of benzoxazoles with secondary amines. Org. Biomol. Chem. 2012, 10 (18), 3715-20.

2.       Li, Y.; * Xie, Y.; Zhang, R.; Jin, K.; Wang, X.; Duan, C. Copper-catalyzed direct oxidative C-H amination of benzoxazoles with formamides or secondary amines under mild conditions. The Journal of organic chemistry 2011, 76 (13), 5444-9.

1.       Li, Y.;* Li, X.; Wang, H.; Chen, T.; Xie, Y. Efficient Copper-Catalyzed S-Arylation of Thiols with Aryl Bromides and Chlorides. Synthesis 2010, 2010 (21), 3602-3608.