代表论文
2024
90. Yin, R.; Wan, P.; Guo, Z.; Yi, X.; Zhang, P.; Shen, W.*; Chen, L.; Xiao, C.*; Chen, X.*, Enzyme-responsive oncolytic polypeptide for tumor therapy. Acta Biomaterialia 2024, 181, 415-424. https://www.sciencedirect.com/science/article/pii/S1742706124002277
89. Guo, Z.; Huang, T.; Yin, R.; Tian, Y.; Wan, P.; Yi, X.; Li, G.; Zhang, P.*; Xiao, C.*; Chen, X.*, Cationic Spherical Polypeptides with Immunogenic Cell Death Inducing Activity for Oncolytic Immunotherapy. CCS Chemistry 2024, 0 (0), 1-14. https://www.chinesechemsoc.org/doi/full/10.31635/ccschem.024.202303793
88. Luo, F.; Li, M.; Chen, Y.; Song, S.; Yu, H.; Zhang, P.*; Xiao, C.*; Lv, G.*; Chen, X., Immunosuppressive enzyme-responsive nanoparticles for enhanced accumulation in liver allograft to overcome acute rejection. Biomaterials 2024, 306, 122476. https://www.sciencedirect.com/science/article/pii/S0142961224000103
87. Yan, Y.; Zhang, X.; Ren, K.*; Xiao, C.*, On-demand dissolvable hydrogel dressings for promoting wound healing. Journal of Polymer Science 2024, 62 (11), 2456-2483. https://onlinelibrary.wiley.com/doi/full/10.1002/pol.20230859
86. Liu, J.; Zhang, X.; Xiao, C.*; Chen, X.*, A Drug-Mineralized Hydrogel Orchestrated by Spontaneous Dynamic Mineralization. Advanced Functional Materials 2024, 34 (12), 2311844. https://onlinelibrary.wiley.com/doi/full/10.1002/adfm.202311844#
85. Liu, Y.; Lin, F.; Wu, C.; Liu, W.; Wang, H.*; Xiao, C.*; Chen, X.*, In Situ Reaction-Generated Aldehyde-Scavenging Polypeptides-Curcumin Conjugate Nanoassemblies for Combined Treatment of Spinal Cord Injury. ACS Nano 2024, 18 (10), 7346-7362. https://pubs.acs.org/doi/full/10.1021/acsnano.3c08662
84. Zhu, Y.; Man, T.; Tian, Y.; Zhang, X.; Liu, J.; Chen, L.*; Xiao, C.*, Dynamic C═C Bond-Based Recyclable Thermosetting Polymers Formed by Knoevenagel Condensation. Macromolecules 2024, 57 (5), 1962-1969. https://pubs.acs.org/doi/full/10.1021/acs.macromol.3c02351
83. He, X.; Yu, J.; Yin, R.; Huang, Y.; Zhang, P.*; Xiao, C.*; Chen, X.*, An AIEgen and Iodine Double-Ornamented Platinum(II) Complex for Bimodal Imaging-Guided Chemo-Photodynamic Combination Therapy. Small 2024, 20 (23), 2309894. https://onlinelibrary.wiley.com/doi/full/10.1002/smll.202309894#
82. He, X.; Yu, J.; Yin, R.; Zhang, P.*; Xiao, C.*; Chen, X.*, A Nanoscale Trans-Platinum(II)-Based Supramolecular Coordination Self-Assembly with a Distinct Anticancer Mechanism. Advanced Materials 2024, 36 (19), 2312488. https://onlinelibrary.wiley.com/doi/full/10.1002/adma.202312488#
81. Liu, H.; Shen, W.*; Liu, W.; Yang, Z.; Yin, D.*; Xiao, C.*, From oncolytic peptides to oncolytic polymers: A new paradigm for oncotherapy. Bioactive Materials 2024, 31, 206-230. https://www.sciencedirect.com/science/article/pii/S2452199X23002475
80. He, P.*; Ren, X.; Zhang, Y.; Tang, B.; Xiao, C.*, Recent advances in sulfur dioxide releasing nanoplatforms for cancer therapy. Acta Biomaterialia 2024, 174, 91-103. https://www.sciencedirect.com/science/article/pii/S174270612300715
2023
79. Zhang, X.; Zhang, P.*; Xiao, C.*; Chen, X., ROS-Responsive Self-Degradable DNA Nanogels for Targeted Anticancer Drug Delivery. ACS Macro Letters 2023, 12 (10), 1317-1323. https://doi.org/10.1021/acsmacrolett.3c00442
78. Zhang, X.; Ren, K.*; Xiao, C.*; Chen, X., Guanosine-driven hyaluronic acid-based supramolecular hydrogels with peroxidase-like activity for chronic diabetic wound treatment. Acta Biomaterialia 2023, 172, 206-217. https://doi.org/10.1016/j.actbio.2023.10.014
77. Zhang, Y.; Liu, X.; He, P.*; Tang, B.; Xiao, C.; Chen, X.*, Thiol-Responsive Polypeptide Sulfur Dioxide Prodrug Nanoparticles for Effective Tumor Inhibition. Biomacromolecules 2023, 24 (9), 4316-4327. https://doi.org/10.1021/acs.biomac.3c00767
76. Yi, X.; Wan, P.; Shen, W.; Zhang, X.; Zhang, P.*; Xiao, C.*, Synthetic lipo-polylysine with anti-cancer activity. Biomaterials Science 2023, 11 (19), 6611-6618. https://doi.org/10.1039/D3BM01099F
75. Liu, J.; Zhang, Z.; Yan, Y.; Zhang, X.; Xiao, C.*; Chen, X.*, Microrod crystals formed via Rhein-mediated mineralization. Chemical Communications 2023, 59 (67), 10169-10172. https://doi.org/10.1039/D3CC02527F
74. Liu, Y.; Zhang, X.*; Xiao, C.*; Liu, B.*, Engineered hydrogels for peripheral nerve repair. Materials Today Bio 2023, 20, 100668. https://doi.org/10.1016/j.mtbio.2023.100668
73. Liu, Y.; Lin, F.; Zhang, T.; Wu, C.; Liu, W.; Wang, H.*; Xiao, C.*; Chen, X.*, Toxic aldehyde-scavenging polypeptides mitigate secondary injury after spinal cord injury. Science China Materials 2023. https://link.springer.com/article/10.1007/s40843-022-2409-4
72. Zhang, X.; Yan, W.*; Song, Z.; Asif, S.; Hussain, I.*; Xiao, C.*; Chen, X., DNA Nanogel for Cancer Therapy. Advanced Therapeutics 2023, 6 (4), 2200287. https://doi.org/10.1002/adtp.202200287
71. Zhang, T.; Wang, Y.; Li, R.; Xin, J.; Zheng, Z.; Zhang, X.; Xiao, C.*; Zhang, S.*, ROS-responsive magnesium-containing microspheres for antioxidative treatment of intervertebral disc degeneration. Acta Biomaterialia 2023, 158, 475-492. https://doi.org/10.1016/j.actbio.2023.01.020
70. Zhang, P.; Zhu, Y.; Xiao, C.*; Chen, X.*, Activatable dual-functional molecular agents for imaging-guided cancer therapy. Advanced Drug Delivery Reviews 2023, 195, 114725. https://doi.org/10.1016/j.addr.2023.114725
2022
69. Luo, F.; Yu, Y.; Li, M.; Chen, Y.; Zhang, P.*; Xiao, C.*; Lv, G.*, Polymeric nanomedicines for the treatment of hepatic diseases. Journal of Nanobiotechnology 2022, 20 (1), 488. https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-022-01708-y
68. Wan, P.; Guo, W.; Wang, Y.; Deng, M.*; Xiao, C.*; Chen, X., Photosensitizer-Polypeptide Conjugate for Effective Elimination of Candida albicans Biofilm. Advanced Healthcare Materials 2022, 11 (16), 2200268. https://doi.org/10.1002/adhm.202200268
67. Luo, F.; Xu, W.; Zhang, J.; Liu, R.; Huang, Y.; Xiao, C.*; Du, J.*, An Injectable Nanocomposite Hydrogel Improves Tumor Penetration and Cancer Treatment Efficacy. Acta Biomaterialia 2022, 147, 235-244. https://doi.org/10.1016/j.actbio.2022.05.042
66. Wan, P.; Guo, W.; Duan, Y.; Deng, M.*; Xiao, C.*, Photosensitizer-Polypeptide Conjugate with Synergistic Antibacterial Efficacy. Macromolecular Bioscience 2022, 22 (7), 2200105. https://doi.org/10.1002/mabi.202200105
65. Guo, W.; Liu, W.; Wan, P.; Wang, H.*; Xiao, C.*; Chen, L.*; Chen, X., Cationic Amphiphilic Dendrons with Anticancer Activity. ACS Biomaterials Science & Engineering 2022, 8 (5), 2121-2130. https://doi.org/10.1021/acsbiomaterials.2c00181
64. Wan, P.; Wang, Y.; Guo, W.; Song, Z.; Zhang, S.; Wu, H.; Yan, W.; Deng, M.*; Xiao, C.*, Low-Molecular-Weight Polylysines with Excellent Antibacterial Properties and Low Hemolysis. ACS Biomaterials Science & Engineering 2022, 8 (2), 903-911. https://doi.org/10.1021/acsbiomaterials.1c01527
63. Sun, S.; Wang, D.; Yin, R.; Zhang, P.; Jiang, R.*; Xiao, C.*, A Two-In-One Nanoprodrug for Photoacoustic Imaging-Guided Enhanced Sonodynamic Therapy. Small 2022, 18 (26), 2202558. https://doi.org/10.1002/smll.202202558
62. Guo, W.; Wang, Y.; Wan, P.; Wang, H.; Chen, L.*; Zhang, S.; Xiao, C.*; Chen, X.*, Cationic amphiphilic dendrons with effective antibacterial performance. Journal of Materials Chemistry B 2022, 10 (3), 456-467. https://pubs.rsc.org/en/content/articlehtml/2022/tb/d1tb02037d
2021
61. Zhang, T.; Lin, F.; Liu, W.; Liu, Y.; Guo, Z.; Xiao, C.*; Zhuang, X.; Chen, X., Reactive oxide species-scavenging lipid-polymer nanoparticles for neuroprotection after spinal cord injury. Applied Materials Today 2021, 24, 101109. https://doi.org/10.1016/j.apmt.2021.101109
60. Ding, X.; Wang, Y.; Liu, J.; Zhang, P.; Li, G.*; Sun, T.*; Xiao, C.*, Injectable In Situ Forming Double-Network Hydrogel To Enhance Transplanted Cell Viability and Retention. Chemistry of Materials 2021, 33 (15), 5885-5895. https://doi.org/10.1021/acs.chemmater.1c00635
59. Zhang, Y.; He, P.; Zhang, P.; Yi, X.; Xiao, C.*; Chen, X.*, Polypeptides–Drug Conjugates for Anticancer Therapy. Advanced Healthcare Materials 2021, 10 (11), 2001974. https://doi.org/10.1002/adhm.202001974
58. Ding, X.; Li, G.; Zhang, P.; Jin, E.; Xiao, C.*; Chen, X., Injectable Self-Healing Hydrogel Wound Dressing with Cysteine-Specific On-Demand Dissolution Property Based on Tandem Dynamic Covalent Bonds. Advanced Functional Materials 2021, 31 (19), 2011230. https://doi.org/10.1002/adfm.202011230
57. Zhang, P.; Li, M.; Xiao, C.*; Chen, X.*, Stimuli-responsive polypeptides for controlled drug delivery. Chemical Communications 2021, 57 (75), 9489-9503. DOI https://doi.org/10.1039/D1CC04053G
56. Zhang, Y.; Zhang, H.; He, P.*; Yi, X.; Liu, X.; Xiao, C.*, A PEGylated alternating copolymeric prodrug of sulfur dioxide with glutathione responsiveness for Irinotecan delivery. Journal of Materials Chemistry B 2021, 9 (1), 187-194. DOI https://doi.org/10.1039/D0TB02097D
55. Lin, X.; Xiao, C.*; Ling, L.; Guo, L.; Guo, X.*, A dual-mode reactive matrix for sensitive and quantitative analysis of carbohydrates by MALDI-TOF MS. Talanta 2021, 235, 122792. https://doi.org/10.1016/j.talanta.2021.122792
54. Guo, L.; Xiao, C.*; Li, J.; Lin, X.; Zhao, N.; Wang, X.; Dong, L.; Guo, X.*, Re-exploring α-Cyano-4-Hydroxycinnamic Acid as a Reactive Matrix for Selective Detection of Glutathione via MALDI-MS. Journal of the American Society for Mass Spectrometry 2021, 32 (12), 2837-2841. https://doi.org/10.1021/jasms.1c00261
53. Wang, Y.; Shen, W.; Liu, S.; Zhu, G.; Meng, X.; Mao, K.; Wang, J.; Yang, Y.-G.; Xiao, C.*; Sun, T.*, The Host-Defense-Peptide-Mimicking Synthetic Polypeptides Effectively Enhance Antitumor Immunity through Promoting Immunogenic Tumor Cell Death. Macromolecular Bioscience 2021, 21 (9), 2100171. https://doi.org/10.1002/mabi.202100171
52. An, L.; Zhang, P.; Shen, W.; Yi, X.; Yin, W.*; Jiang, R.*; Xiao, C.*, A sulfur dioxide polymer prodrug showing combined effect with doxorubicin in combating subcutaneous and metastatic melanoma. Bioactive Materials 2021, 6 (5), 1365-1374. https://doi.org/10.1016/j.bioactmat.2020.10.027
2020
51. Zhang, P.; Zhang, Y.; Ding, X.; Shen, W.; Li, M.; Wagner, E.; Xiao, C.*; Chen, X.*, A Multistage Cooperative Nanoplatform Enables Intracellular Co-Delivery of Proteins and Chemotherapeutics for Cancer Therapy. Advanced Materials 2020, 32 (46), 2000013. https://doi.org/10.1002/adma.202000013
50. Shen, W.; Zhang, Y.; Wan, P.; An, L.; Zhang, P.; Xiao, C.*; Chen, X.*, Antineoplastic Drug-Free Anticancer Strategy Enabled by Host-Defense-Peptides-Mimicking Synthetic Polypeptides. Advanced Materials 2020, 32 (36), 2001108. https://doi.org/10.1002/adma.202001108
49. Zhang, Y.; Shen, W.; Zhang, P.; Chen, L.*; Xiao, C.*, GSH-triggered release of sulfur dioxide gas to regulate redox balance for enhanced photodynamic therapy. Chemical Communications 2020, 56 (42), 5645-5648. DOI https://doi.org/10.1039/D0CC00470G
48. Ding, X.; Li, G.; Zhang, P.; Xiao, C.*, Constructing Thermally Reversible Dynamic Hydrogels via Catalysis-Free Knoevenagel Condensation. ACS Macro Letters 2020, 9 (6), 830-835. https://doi.org/10.1021/acsmacrolett.0c00330
47. Zhang, T.; Yao, J.; Tian, J.; Deng, M.; Zhuang, X.*; Xiao, C.*, Synthesis of polypeptide bearing 1,4-dithiane pendants for ROS-responsive drug release. Chinese Chemical Letters 2020, 31 (5), 1129-1132. https://doi.org/10.1016/j.cclet.2019.07.010
46. Zhang, P.; Yang, H.; Shen, W.; Liu, W.; Chen, L.; Xiao, C.*, Hypoxia-Responsive Polypeptide Nanoparticles Loaded with Doxorubicin for Breast Cancer Therapy. ACS Biomaterials Science & Engineering 2020, 6 (4), 2167-2174. https://doi.org/10.1021/acsbiomaterials.0c00125
45. Zhang, P.; Zhang, Y.; Ding, X.; Xiao, C.*; Chen, X., Enhanced nanoparticle accumulation by tumor-acidity-activatable release of sildenafil to induce vasodilation. Biomaterials Science 2020, 8 (11), 3052-3062. https://doi.org/10.1039/D0BM00466A
2019
44. Chen, X.; Xiao, C.*; Chen, X.*, Synthesis of PEGylated Salicylaldehyde Azine via Metal-free Click Chemistry for Cellular Imaging Applications. Chemical Research in Chinese Universities 2019, 35 (5), 929-936.
43. Song, L.; Zhang, B.; Gao, G.; Xiao, C.*; Li, G.*, Single component Pluronic F127-lipoic acid hydrogels with self-healing and multi-responsive properties. European Polymer Journal 2019, 115, 346-355. https://doi.org/10.1016/j.eurpolymj.2019.03.051
42. Ding, X.; Wang, Y.; Li, G.*; Xiao, C.*; Chen, X., Iminoboronate ester cross-linked hydrogels with injectable, self-healing and multi-responsive properties. Acta Polymerica Sinica 2019, 50 (5), 505-515. http://www.gfzxb.org/thesisDetails#10.11777/j.issn1000-3304.2019.19015&lang=zh
41. Ding, X.; Li, G.*; Xiao, C.*; Chen, X., Enhancing the Stability of Hydrogels by Doubling the Schiff Base Linkages. Macromolecular Chemistry and Physics 2019, 220 (3), 1800484. https://doi.org/10.1002/macp.201800484
40. Chen, X.; Yang, H.; Xiao, C.*; Chen, X.*, Facile Synthesis of Resveratrol Nanogels with Enhanced Fluorescent Emission. Macromolecular Bioscience 2019, 19 (2), 1800438. https://doi.org/10.1002/mabi.201800438
39. Zhang, Y.; He, P.; Liu, X.; Yang, H.; Zhang, H.; Xiao, C.*; Chen, X.*, A PEGylated alternating copolymer with oxidation-sensitive phenylboronic ester pendants for anticancer drug delivery. Biomaterials Science 2019, 7 (9), 3898-3905. https://doi.org/10.1039/C9BM00884E
38. Bao, X.; Si, X.; Ding, X.; Duan, L.*; Xiao, C.*, pH-responsive hydrogels based on the self-assembly of short polypeptides for controlled release of peptide and protein drugs. Journal of Polymer Research 2019, 26 (12), 278. https://link.springer.com/article/10.1007/s10965-019-1953-8
37. Wang, S.; Xiao, C.*; Guo, L.; Ling, L.; Li, M.; Li, H.; Guo, X.*, Rapidly quantitative analysis of γ-glutamyltranspeptidase activity in the lysate and blood via a rational design of the molecular probe by matrix-assisted laser desorption ionization mass spectrometry. Talanta 2019, 205, 120141. https://doi.org/10.1016/j.talanta.2019.120141
36. Yao, J.; He, P.*; Zhang, Y.; Zhang, H.; Zhang, P.; Deng, M.*; Xiao, C.*, PEGylated polylysine derived copolymers with reduction-responsive side chains for anticancer drug delivery. Polymer International 2019, 68 (10), 1817-1825. https://doi.org/10.1002/pi.5892
35. Ling, L.; Xiao, C.*; Wang, S.; Guo, L.; Guo, X.*, A pyrene linked peptide probe for quantitative analysis of protease activity via MALDI-TOF-MS. Talanta 2019, 200, 236-241. https://doi.org/10.1016/j.talanta.2019.03.055
34. Ling, L.; Xiao, C.*; Ma, Y.; Jiang, L.; Wang, S.; Guo, L.; Jiang, S.; Guo, X.*, 2-Phenyl-3-(p-aminophenyl) Acrylonitrile: A Reactive Matrix for Sensitive and Selective Analysis of Glycans by MALDI-MS. Analytical Chemistry 2019, 91 (14), 8801-8807. https://doi.org/10.1021/acs.analchem.9b01434
33. Guo, L.; Xiao, C.*; Wang, S.; Gao, T.; Ling, L.; Guo, X.*, Quantitation of Glutathione by Quinoline-5, 8-Dione-Based Tag Strategy Using MALDI Mass Spectrometry. Journal of the American Society for Mass Spectrometry 2019, 30 (4), 625-633. https://doi.org/10.1007/s13361-019-02135-4
2018
32. Zhang, Y.; He, P.; Liu, X.; Zhang, H.; Yang, H.; Xiao, C.*; Chen, X.*, Synthesis of PEGylated alternating copolymer bearing thioether pendants for oxidation responsive drug delivery. European Polymer Journal 2018, 107, 308-314. https://doi.org/10.1016/j.eurpolymj.2018.09.004
31. Shen, W.; He, P.; Xiao, C.*; Chen, X.*, From Antimicrobial Peptides to Antimicrobial Poly(α-amino acid)s. Advanced Healthcare Materials 2018, 7 (20), 1800354. https://doi.org/10.1002/adhm.201800354
30. Wu, C.; Xiao, C.*; Chen, X.*, Application of Frustrated Lewis Pairs in Polymerization. Chinese Journal of Applied Chemistry 2018, 35 (9), 1013.
29. Li, Y.; Yang, H.; Yao, J.; Yu, H.; Chen, X.; Zhang, P.*; Xiao, C.*, Glutathione-triggered dual release of doxorubicin and camptothecin for highly efficient synergistic anticancer therapy. Colloids and Surfaces B: Biointerfaces 2018, 169, 273-279. https://doi.org/10.1016/j.colsurfb.2018.05.025
28. Shen, W.; Liu, W.; Yang, H.; Zhang, P.; Xiao, C.*; Chen, X.*, A glutathione-responsive sulfur dioxide polymer prodrug as a nanocarrier for combating drug-resistance in cancer chemotherapy. Biomaterials 2018, 178, 706-719. https://doi.org/10.1016/j.biomaterials.2018.02.011
27. Song, L.; Zhang, B.; Jin, E.; Xiao, C.*; Li, G.*; Chen, X., A reduction-sensitive thermo-responsive polymer: Synthesis, characterization, and application in controlled drug release. European Polymer Journal 2018, 101, 183-189. https://doi.org/10.1016/j.eurpolymj.2018.02.022
26. Xiao, C.; Ding, J.; He, C.; Chen, X., Glycopolypeptides: Synthesis, self-assembly and biomedical applications. ACTA POLYMERICA SINICA 2018, (1), 45-55.
25. Yang, H.; Shen, W.; Liu, W.; Chen, L.*; Zhang, P.*; Xiao, C.*; Chen, X., PEGylated Poly(α-lipoic acid) Loaded with Doxorubicin as a pH and Reduction Dual Responsive Nanomedicine for Breast Cancer Therapy. Biomacromolecules 2018, 19 (11), 4492-4503. https://doi.org/10.1021/acs.biomac.8b01394
24. Yan, Y.; Cao, Y.; Xiao, C.*; Li, Y.; Xiang, X.; Guo, X.*, 5′-(CGA)n sequence-assisted pH-controlled assembly of supramolecular DNA nanostructure. Royal Society Open Science 5 (8), 180123. https://doi.org/10.1098/rsos.180123
23. Du, Y.; Yan, W.*; Lian, H.; Xiang, C.; Duan, L.*; Xiao, C.*, 2,2′-Dithiodisuccinic acid-stabilized polyion complex micelles for pH and reduction dual-responsive drug delivery. Journal of Colloid and Interface Science 2018, 522, 74-81. https://doi.org/10.1016/j.jcis.2018.03.049
22. Wang, S.; Xiao, C.*; Jiang, L.; Ling, L.; Chen, X.; Guo, X.*, A high sensitive and contaminant tolerant matrix for facile detection of membrane proteins by matrix-assisted laser desorption/ionization mass spectrometry. Analytica Chimica Acta 2018, 999, 114-122. https://doi.org/10.1016/j.aca.2017.11.018
21. Ling, L.; Li, Y.; Wang, S.; Guo, L.; Xiao, C.*; Chen, X.; Guo, X.*, DBDA as a Novel Matrix for the Analyses of Small Molecules and Quantification of Fatty Acids by Negative Ion MALDI-TOF MS. Journal of the American Society for Mass Spectrometry 2018, 29 (4), 704-710. https://doi.org/10.1007/s13361-017-1881-y
2017
20. Zhang, T.*; Xiao, C.*; Zhuang, X.*; Chen, X., Synthesis of phenylboronic ester-linked Y-shape polymer via passerini reaction for ROS-responsive drug delivery. Journal of Controlled Release 2017, 259, e126.
19. Jin, E.; Zhang, Z.; Lian, H.; Chen, X.; Xiao, C.*; Zhuang, X.; Chen, X.*, Injectable electroactive hydrogels based on Pluronic® F127 and tetraaniline copolymer. European Polymer Journal 2017, 88, 67-74. https://doi.org/10.1016/j.eurpolymj.2017.01.013
18. Zhang, T.; Chen, X.; Xiao, C.*; Zhuang, X.*; Chen, X., Synthesis of a phenylboronic ester-linked PEG-lipid conjugate for ROS-responsive drug delivery. Polymer Chemistry 2017, 8 (40), 6209-6216. https://doi.org/10.1039/C7PY00915A
17. Lian, H.; Du, Y.; Chen, X.; Duan, L.*; Gao, G.; Xiao, C.*; Zhuang, X., Core cross-linked poly(ethylene glycol)-graft-Dextran nanoparticles for reduction and pH dual responsive intracellular drug delivery. Journal of Colloid and Interface Science 2017, 496, 201-210. https://doi.org/10.1016/j.jcis.2017.02.032
16. Liu, W.; Gu, R.; Zhu, Q.*; Xiao, C.*; Huang, L.; Zhuang, X.; Zhang, J.; Liu, L.; Ma, B.; Yang, H.; Ma, J.; Hu, Z.; Tang, C.*; Zhao, S.*; Chen, X., Rapid fluorescence imaging of spinal cord following epidural administration of a nerve-highlighting fluorophore. Theranostics 2017, 7 (7), 1863-1874. https://www.thno.org/v07p1863.htm
15. Hu, Y.; Deng, M.; Yang, H.; Chen, L.*; Xiao, C.*; Zhuang, X.; Chen, X., Multi-responsive core-crosslinked poly (thiolether ester) micelles for smart drug delivery. Polymer 2017, 110, 235-241. https://doi.org/10.1016/j.polymer.2017.01.019
14. Wang, S.; Xiao, C.*; Li, Y.; Ling, L.; Chen, X.; Guo, X.*, A Surface Pattern on MALDI Steel Plate for One-Step In-Situ Self-Desalting and Enrichment of Peptides/Proteins. Journal of the American Society for Mass Spectrometry 2017, 28 (3), 428-433. https://doi.org/10.1007/s13361-016-1584-9
13. Ling, L.; Xiao, C.*; Jiang, L.; Wang, S.; Li, Y.; Chen, X.; Guo, X.*, A cool and high salt-tolerant ionic liquid matrix for preferential ionization of phosphopeptides by negative ion MALDI-MS. New Journal of Chemistry 2017, 41 (20), 12241-12249. https://doi.org/10.1039/C7NJ01706E
2016
12. Wang, S.; Xiao, Z.; Xiao, C.*; Wang, H.; Wang, B.; Li, Y.; Chen, X.; Guo, X.*, (E)-Propyl α-Cyano-4-Hydroxyl Cinnamylate: A High Sensitive and Salt Tolerant Matrix for Intact Protein Profiling by MALDI Mass Spectrometry. Journal of the American Society for Mass Spectrometry 2016, 27 (4), 709-718. https://doi.org/10.1007/s13361-015-1325-5
11. Zhang, Y.; Ding, J.; Li, M.; Chen, X.; Xiao, C.*; Zhuang, X.; Huang, Y.; Chen, X.*, One-Step “Click Chemistry”-Synthesized Cross-Linked Prodrug Nanogel for Highly Selective Intracellular Drug Delivery and Upregulated Antitumor Efficacy. ACS Applied Materials & Interfaces 2016, 8 (17), 10673-10682. https://doi.org/10.1021/acsami.6b00426
2015
10. Xiao, C.; Ding, J.; Zhuang, X.; Chen, X.*, PEG-based thermo-responsive poly (β-thioether ester) for ROS-triggered drug delivery. Journal of controlled release : official journal of the Controlled Release Society 2015, 213, e22. https://doi.org/10.1016/j.jconrel.2015.05.033
9. Xiao, C.; Ding, J.; Ma, L.; Yang, C.; Zhuang, X.; Chen, X.*, Synthesis of thermal and oxidation dual responsive polymers for reactive oxygen species (ROS)-triggered drug release. Polymer Chemistry 2015, 6 (5), 738-747. https://doi.org/10.1039/C4PY01156B
2014
8. Xiao, C.; Cheng, Y.; Zhang, Y.; Ding, J.; He, C.; Zhuang, X.; Chen, X.*, Side chain impacts on pH-and thermo- responsiveness of tertiary amine functionalized polypeptides. Journal of Polymer Science Part A-Polymer Chemistry 2014, 52 (5), 671-679. https://doi.org/10.1002/pola.27048
2013
7. Ding, J.; Xu, W.; Zhang, Y.; Sun, D.; Xiao, C.*; Liu, D.; Zhu, X.*; Chen, X.*, Self-reinforced endocytoses of smart polypeptide nanogels for “on-demand” drug delivery. Journal of Controlled Release 2013, 172 (2), 444-455. https://doi.org/10.1016/j.jconrel.2013.05.029
6. Zhang, J.; Xiao, C.*; Wang, J.; Zhuang, X.; Chen, X., Photo cross-linked biodegradable hydrogels for enhanced vancomycin loading and sustained release. Chinese Journal of Polymer Science 2013, 31 (12), 1697-1705. https://link.springer.com/article/10.1007/s10118-013-1358-9
5. Xiao, C.; Ding, J.; Li, Y.; Zhuang, X.; He, C.; Chen, X.*, Physical interaction induced self-assembly of glycopeptide and doxorubicin at physiological pH as promising hepatoma-targeted nanomedicine. Journal of Controlled Release 2013, 172 (1), e23-e24. https://doi.org/10.1016/j.jconrel.2013.08.055
4. Ding, J.; Zhao, L.; Li, D.; Xiao, C.*; Zhuang, X.*; Chen, X., Thermo-responsive “hairy-rod” polypeptides for smart antitumor drug delivery. Polymer Chemistry 2013, 4 (11), 3345-3356. https://doi.org/10.1039/C3PY00144J
2010
3. Xiao, C.; Zhao, C.; He, P.; Tang, Z.; Chen, X.*; Jing, X., Facile Synthesis of Glycopolypeptides by Combination of Ring-Opening Polymerization of an Alkyne-Substituted N-carboxyanhydride and Click "Glycosylation". Macromolecular Rapid Communications 2010, 31 (11), 991-997. https://doi.org/10.1002/marc.200900821
2009
1. Xiao, C.; Tian, H.; Zhuang, X.; Chen, X.*; Jing, X., Recent developments in intelligent biomedical polymers. Science in China Series B: Chemistry 2009, 52 (2), 117-130. https://link.springer.com/article/10.1007/s11426-008-0151-z
2006
1. Xiao, C.; Wang, Y.; Du, J.; Chen, X.; Wang, J.*, Kinetics and Mechanism of 2-Ethoxy-2-oxo-1,3,2-dioxaphospholane Polymerization Initiated by Stannous Octoate. Macromolecules 2006, 39 (20), 6825-6831. https://doi.org/10.1021/ma0615396
